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PubMedDate not supplied

Indiana residents polled on insurance, malpractice.

The Indiana State Medical Association contracted with The Gallup Organization, Inc. of Princeton, N.J., to conduct a statewide assessment of Indiana households regarding attitudes and behaviors toward health care services and issues. Telephone interviews of 1,010 randomly selected adult heads of households were conducted in August 1991. At the 91% level of confidence, the maximum expected error range for a sample of 1,010 respondents is +/- 3.1%. Data were analyzed across key demographics including respondent age, race and geographic location. In addition, counties were classified as urban, rural or "mixed" (those in which a substantial metropolitan area was set in an overall rural area).

Attitude of Health Personnel↗
PubMed1992

Iguana-associated salmonellosis--Indiana, 1990.

During 1990, the Indiana State Board of Health's Disease Control Laboratory reported isolates of a rare Salmonella serotype, S. marina, from two infants residing in different Indiana counties. This report summarizes epidemiologic and clinical information about these two cases.

Animals↗
PubMed1991

Practice randomization and clinical research. The Indiana experience.

Thoughtful preparation of a research laboratory is an early step in designing a program for scientific investigation. The Division of General Internal Medicine at Indiana University has maintained a "laboratory" for outpatient clinical investigation for more than 15 years. In this report, we describe the structure and function of the General Medicine Practice in the Regenstrief Health Center on the campus of the Indiana University School of Medicine in Indianapolis. Specifically, we discuss the ongoing random allocation of subjects, the local resources for data management and tracking of patients' use of clinical services, and how combining this information system into a randomized primary care system has fostered successful ventures in clinical investigation.

Health Services Research↗
PubMed1989

Gastropod intermediate hosts of Parelaphostrongylus tenuis (Nematoda: Metastrongyloidea) from northwestern Indiana.

Thirteen species of terrestrial gastropods from the Kingsbury State Fish and Wildlife Area, Indiana, were examined for the presence of third-stage larvae (L3s) of the meningeal worm, Parelaphostrongylus tenuis, during the summers of 1987 and 1988. Three (Deroceras laeve, Discus cronkhitei, and unidentified species of Cochlicopa [= Cionella]) were infected. Prevalence of infection was low, 1.1% and 2.7% in 1987 and 1988, respectively. The highest prevalence was 5.5% in Cochlicopa spp.; however, most of the larvae from this host were recently molted second-stage larvae (L2s). Attempts to identify foci of infection based on vegetation cover, soil pH, and replaceable calcium levels in the soil were unsuccessful. This is the first report of P. tenuis from Indiana.

Animals↗
PubMedDate not supplied

Analysis of orthodontic treatment by pediatric dentists and general practitioners in Indiana.

This investigation analyzed the extent of orthodontic services currently being provided by pediatric dentists and general practitioners in Indiana. All 71 Indiana pediatric dentists primarily in private practice and 500 general practitioners were mailed a survey/questionnaire. Sixty-two percent of the pediatric dentists and 17.9 percent of the general practitioners surveyed provided comprehensive orthodontic treatment, results much higher than those of previous surveys of pediatric dentists and general practitioners. Pediatric dentists were found to provide significantly more comprehensive orthodontic treatment and spend significantly more time providing orthodontic treatment than general practitioners, especially those in communities of less than 25,000. Sixty-three percent of the practitioners surveyed had taken some type of continuing education in orthodontics. These practitioners spent significantly (p less than 0.001) more time treating orthodontic conditions, and treated more complex cases than those who had not taken such courses.

Adult↗
PubMed1970

The Indiana Biomedical Information Program.

In 1966, the Indiana University School of Medicine Library became part of a statewide teletype network. Biomedical personnel throughout Indiana may use the resources of the Library by requesting either specific books and articles or bibliographic searches through local public libraries which relay the requests to the School of Medicine Library. All transactions except reference questions receive twenty-four-hour service. The popularity of such a facility is indicated by the fact that 472 identified borrowers used it during the twenty-five months between its inception and December 31, 1968. Over half of the borrowers have used it repeatedly, and as many as 358 transactions have occurred in a single month. The largest group of borrowers consists of practicing physicians. It is felt that the enthusiastic response to the service justifies its continuation and expansion.

Indiana↗
PubMed1980

Pesticides and PCB residues in the Black Creek Watershed, Allen County, Indiana--1977-78.

The aquatic environment of a small agricultural drainage in northeastern Indiana was surveyed during 1977-78 for pesticide and PCB contamination. A total of 45 water, sediment, and fish samples from Black Creek watershed, Allen County, Indiana were analyzed for seven pesticides and PCBs. Low levels of dieldrin (mean 0.023 micrograms/g) and DDE (mean 0.016 micrograms/g) were found in all fish samples, but were not detected in water or sediment samples. PCB concentrations in fish were five times greater (0.102 micrograms/g) than were organochlorine pesticide concentrations. Two of seven water samples contained PCBs at 0.4 micrograms/liter and 0.2 micrograms/liter. Only the herbicide 2,4,5-T occurred in surface water samples during low stream discharge, at concentrations of 0.2--7.7 micrograms/liter. Atrazine, alachlor, carbofuran, and malathion were not detected in any samples.

Animals↗
PubMedDate not supplied

A one-year review of the Eye Injury Registry of Indiana.

In the first year of operation, the Eye Injury Registry of Indiana collected data on 171 severe eye injuries and categorized them according to the circumstances of the injury, severity of tissue disruption and visual function. Many preventable causes of injury were documented. By understanding the contributors of accidental injury, prevention strategies can be implemented. This collaborative project should continue to provide useful information specific to Indiana concerning the root causes of eye injury.

Adolescent↗
PubMedDate not supplied

A survey of expanded duties usage in Indiana: a pilot study.

PURPOSE: The information presented in this pilot study was obtained as part of a 1990 survey of Indiana dentists. This portion of the study determined the number and types of expanded duties delegated to dental hygienists and the relationship of this information to their employer's year of graduation. METHODS: A 10% random sample of Indiana dentists was sent a questionnaire that asked each practitioner's specialty and year of graduation from dental school. In addition, the number of dental hygienists and assistants employed in the practice and the frequency of selected expanded function procedures they performed were determined. Statistical treatment of the survey data was accomplished by frequency tabulations on procedures delegated; principal component analysis applied to a select number of measures; and Student's t-test to variables related to office environment (total years experience, total staff, percentage employing dental hygienists, percentage employing full-time dental hygienists, number of procedures employed, and graduation year of dentist). The level of significance selected for the t-test analysis was .05. RESULTS AND CONCLUSIONS: Seventy-four questionnaires were returned out of 231 mailed (32% response rate). Of the expanded functions listed on the survey, the procedures most widely delegated to dental hygienists were amalgam polishing and sealant placement. The placement of resin and amalgam restorations was rarely performed by dental hygienists. Based on a principal component analysis, two office environments were defined. Type A offices had dentists with a mean graduation date of 1965.9. Type B offices had dentists with a mean graduation date of 1977.8, significantly larger staff sizes, and employed a higher percentage of full-time dental hygienists. Moreover, dental hygienists employed in Type B offices also performed a greater number of expanded function procedures than did dental hygienists in Type A offices.

Dental Assistants↗
PubMedDate not supplied

Tobacco use by Indiana children and adolescents.

Data from a five-year, longitudinal survey of cigarette smoking and smokeless tobacco use by Indiana children and adolescents are presented. A four-page, self-contained questionnaire was used to collect anonymous information from more than 240,000 students in grades six through 12. Indiana students reported prevalence levels 20% to 50% higher than levels reported in comparable national surveys. Perceived risk of physical or psychological harm was the single best statistical predictor of whether or not a student would choose to use tobacco. Tobacco use was statistically linked to increased use of illicit drugs. Physicians can play a powerful role in influencing a patient's perception of the risks associated with cigarette smoking.

Adolescent↗
PubMed1995

Competency-based education at the Indiana University School of Dentistry.

This article discusses competency-based education at Indiana University School of Dentistry (IUSD). Competency-based education is not a new concept in health education, but is relatively new to dental education. The authors hope that this article will help Indiana dentists understand a process that will radically alter the way we teach dentistry at IUSD.

Clinical Competence↗
PubMed1995

A report on Indiana PANDA. Prevention of Abuse and Neglect through Dental Awareness.

Since originally surveying Indiana dentists' knowledge of child abuse and neglect in 1990, numerous efforts have been made to help dental professionals improve their ability to identify and report instances of abuse. This article explains the purpose for the 1995 follow-up survey and why dental professionals' assistance is needed to complete the surveys. A second survey is scheduled for distribution six months after the Prevention of Abuse and Neglect through Dental Awareness (PANDA) efforts have been implemented to determine if those efforts are far having an effect throughout Indiana.

Child↗
PubMed1991

Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58.

Gerstmann-Sträussler-Scheinker (GSS) disease is a familial neurological disorder pathologically characterized by amyloid deposition in the cerebrum and cerebellum. The GSS amyloid is immunoreactive to antisera raised against the hamster prion protein (PrP) 27-30. This is a proteinase K-resistant glycoprotein of 27-30 kd that is derived from an abnormal isoform of a neuronal glycoprotein of 33-35 kd designated PrPSc and is a molecular marker of amyloid fibrils isolated from animals with scrapie and humans with related disorders. We have purified and characterized proteins extracted from amyloid plaque cores isolated from two patients of the Indiana kindred of GSS disease. We found that the major component of GSS amyloid is an 11 kd degradation product of PrP, whose N-terminus corresponds to the glycine residue at position 58 of the amino acid sequence deduced from the human PrP cDNA. In addition, amyloid fractions contained larger PrP fragments with apparently intact N-termini and amyloid P component. These findings suggest that the disease process leads to proteolytic cleavage of PrP, generating an amyloidogenic peptide that polymerizes into insoluble fibrils. The N-terminal cleavage of PrP in GSS disease occurs at a tryptophan-glycine peptide bond identical to that cleaved by proteinase K in vitro to generate PrP 27-30 from hamster PrPSc at codon 90. Since no mutations of the structural PrP gene have been found in the Indiana family of GSS disease, it is conceivable that factors other than the primary structure of PrP play a crucial role in the process of amyloid formation and the development of clinical neurologic dysfunction.

Amino Acid Sequence↗
PubMed1996

Present experience with the Indiana pouch.

The Indiana pouch was developed as a modification of the Glichrist procedure in 1984. The need for full detubularization of the reservoir was recognized early and was achieved by an ileal patch on the cecal reservoir or by an antimesenteric incision of the cecal segment with folding and transverse closure, the efferent limb and continence mechanism were modified to promote ease of catheterization and improved continence. These modifications gave markedly better results with lower reoperation rates. A group of 81 patients with a minimum of 2 years of follow-up are reported herein. The most recent modification uses absorbable GIA and TA55 staples to detubularize and close the reservoir. This stapling technique has been employed in 20 patients and has resulted in decreased operating times without any significant increase in complications. In its current form, the Indiana pouch meets all the criteria for a satisfactory continent cutaneous reservoir and has a favorable reoperation rate as compared with other pouches.

Cecum↗
PubMed1990

Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease.

In the Indiana kindred of Gerstmann-Sträussler-Scheinker disease, neurofibrillary tangles (NFT) with paired helical filaments (PHF) are numerous, widespread and consistently present in the cerebral cortex and several subcortical nuclei. Such tangles share antigenic determinants with those of Alzheimer disease; in fact, they are recognized by Alz50, anti-PHF and anti-ubiquitin antibodies. Thus, NFT with structural and immunocytochemical similarities are present in two distinct forms of amyloidosis of the central nervous system, i.e. the Indiana kindred of Gerstmann-Sträussler-Scheinker disease and Alzheimer disease.

Aged↗
PubMed1991

Modified Indiana pouch.

The modified continent Indiana pouch is based upon the terminal 8 to 12 cm. of ileum and 26 to 30 cm. of right colon. Our modifications include complete detubularization of the colonic segment with an easier appendectomy, a transcolonic ureteral reimplantation that is technically simple and reinforced plication of the ileocecal junction. This procedure was performed in 70 patients (ages 27 to 85 years) with followup ranging between 3 and 24 months. There have been 5 hospitalizations for urinary tract infections or gastrointestinal complications. Open surgical revision (4%) has been necessary for incontinence in 1 case, for a redundant ileal limb and difficult catheterization in 1, and for ureteral stenosis in the mid portion of the left ureter in 1. A revision procedure is pending for inadequate reservoir volume. Endoscopic meatotomy of ureterocolonic junction strictures has been necessary in 2 cases. All patients are continent day and night with easy catheterization of volumes ranging between 400 and 800 cc. The modified Indiana pouch should be considered for any patient requiring cutaneous urinary diversion because of a low complication and revision rate, and an excellent continence rate.

Adult↗