Halogenated 1-(4-aminobenzylidene)indenes.
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Animals↗
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Metal chelate steroid analog. [7-Amino-3-(1,5-dimethylhexyl)dodecahydro-3a,6-dimethyl-1H-benz[e]indene-6-methylamine]bis(ethylenediamine)cobalt(3 plus) trichloride.
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Amines↗
Analogs of 1-(4-dimethylaminobenzylidene)indene. Modifications of the amino group.
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Animals↗
Benzylideneindenes with oxygen attached to the indene ring.
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Animals↗
BENZYLIDENE DERIVATIVES OF INDENE AND CYCLOPENTADIENE.
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Antineoplastic Agents↗
Neurosteroid analogues. 7. A synthetic route for the conversion of 5 beta-methyl-3-ketosteroids into 7(S)-methyl-substituted analogues of neuroactive benz[e]indenes.
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Anesthetics, Intravenous↗
Induction of mammary and other subcutaneous neoplasms in rats by 1-(4-dimethylaminobenzal)-indene.
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Animals↗
Synthesis and stability of 2-methyl-2,4-diaza- and 2-methyl-2,5-diaza-indene (2-methyl-pyrrolo(3,4-b)pyridine and -pyrrolo(3,4-c)pyridine).
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Aza Compounds↗
Biochemical studies of toxic agents. 9. The metabolic conversion of indene into cis- and trans- indane-1: 2-diol.
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Benzene↗
The role of 1,2-epoxyindene in the metabolism of indene in vivo [proceedings].
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Animals↗
[1a(1a alpha,5 beta,9a alpha)]-1,1a,4,5,7,8,9,9a-Octahydro-3-hydroxy-1,1,2,5- tetramethyl-7-methylene-6H-cyclopropa-[3,4]cyclohept[1,2-e] inden-6-one.
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Crystallography, X-Ray↗
Evaluation of anti-allergic effects of 1-substituted 2-n-butyl-methylenedioxy indenes.
The effects of ten 1-substituted 2-n-butyl-5,6-methylenedioxyindenes on mice and guinea pigs were investigated for their allergic reactions in the development of a new anti-allergic drug. Anti-allergic effects were determined by testing the effect of agents on passive cutaneous anaphylaxis (PCA) in mice and Schultz-Dale reaction in guinea pig tracheal muscle. 2-Butyl-1-[N-methyl-N-[2-(N',N'-dimethylamino) ethyl]amino]5,6- methylenedioxyindene (1) indicated the most potent anti-allergic activity. Since our previous experiments indicated that 2-n-butyl 3-dimethyl amino-5,6-methylenedioxyindene (MDI-A) and its derivatives showed a potent anti-allergic effect by interfering with the calcium (Ca) movement in the allergic reaction in guinea pigs, the effect of 1 and MDI-A on allergic reaction and Ca-induced contraction of tracheal muscle in these animals were compared. The present data indicate the superiority of 1 in both reactions.
Animals↗
[Indene and related compounds. V. Ring expansion of 2-nitro-1-indanone oxime with polyphosphoric acid. (Studies on the syntheses of heterocyclic compounds. 173.)].
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Chemical Phenomena↗
[Synthesis of new indene derivatives with -adrenergic blocking properties].
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Adrenergic beta-Antagonists↗
[Determination of residues of hepatchlor (1,4,5,6,7,8,8-hepatachlor-3a,4,7,7a-tetranydro-4,7-methano indene) in olive oil].
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Indenes↗
A new, potent antihistamine: dimethpyr indene. A preliminary report.
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Anti-Allergic Agents↗
[Hygienic evaluation and standardization of naphthoquinone diazine derivatives and indene in water].
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Animals↗
[Synthesis of new indene derivatives].
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Analgesics↗