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At least 127 records · Page 7Linked to original sources

Effect of slow-release ISDN on cardiac function in patients with coronary heart disease during bicycle ergometry.

In 10 patients with coronary heart disease (CHD), the effect of a single doses of slow-release isosorbide dinitrate (ISDN) on cardiac function was investigated. Haemo-dynamics was examined by right heart catheterization and thermodilution measurement of cardiac output. After placebo and after 2 and 6 hours with 40 mg ISDN, the heart rate (HR), cardiac index (CI), pressure values in the pulmonary artery (PASP, PAMP, PAEDP) and in the aorta (AoSP, AoMP, AoEDP) and systemic vascular resistance (SVR) were measured at rest and during bicycle ergometry. At rest, PASP and PAMP were significantly reduced only 6 hours after ISDN. Under exercise conditions, significantly reduced pressure values in the pulmonary artery were found 2 and 6 hours after ISDN. AoSP was likewise reduced 2 and 6 hours after ISDN. HR, CI and SVR showed no significant differences compared with placebo values. Thus, an effective reduction of left ventricular preload and afterload was seen in patients with CHD during bicycle ergometry.

Adult↗

[Bicycle ergometry test and the work incapacity of men 40 to 59].

The purpose of the investigation was to study the relationship between indicators of the bicycle ergometry test and temporary disability degree in males aged 40 to 59 residing in the area of 2 district outpatient clinics in Moscow. Disability (temporary, stable) was studied by a method of standard interviewing. The bicycle ergometry test was applied to each patient using a standard scheme. The investigation showed an inverse ration between physical exercise tolerance and disability degree.

Absenteeism↗

[Intravenous isoproterenol administration for diagnosing ischemic heart disease in women: a comparison with the data from bicycle ergometry and selective coronary angiography].

The significance of the test with intravenous injection of isoproterenol in the diagnosis of coronary heart disease (CHD) was evaluated in comparison with the clinical, bicycle ergometry and selective coronarography data obtained in 65 women. Twenty-four patients presented with stenosing coronary atherosclerosis and 41 patients had normal coronary arteries. On the use of the electrocardiographic signs of myocardial ischemia the sensitivity of the isoproterenol test in the diagnosis of hemodynamically appreciable coronary atherosclerosis was 74%, the specificity 78%. The sensitivity and specificity of bicycle ergometry were 66 and 90%, respectively.

Adult↗

[Comparison of the results of transesophageal electrical stimulation of the left atrium, bicycle ergometry and selective coronary angiography in diagnosing ischemic heart disease].

The clinical picture and results of bicycle ergometry and selective coronarography were compared with data obtained by esophageal electric stimulation of the left atrium in 108 patients with suspected coronary disease. It was demonstrated that esophageal left-atrial electrostimulation could be used as noninvasive load test for coronary disease. Ischemic electrocardiographic changes, induced by esophageal stimulation showed good correlation to the clinical manifestation of angina pectoris and the severity of coronary atherosclerosis. The sensitivity of esophageal stimulation in the diagnosis of hemodynamically-significant coronary atherosclerosis was 82%, its specificity was 76%, the predictive value of positive results was 82%, and the predictive value of negative results, 76%, that is, essentially the same as the respective parameters of bicycle ergometry.

Adolescent↗

[Stress studies with dipyridamole in patients with coronary heart disease in comparison to coronary angiography, myocardial scintigraphy and ergometry findings].

In 102 patients with typical symptoms of angina pectoris who underwent a coronary angiography a Dipyridamol test was performed. The result was a sensitivity of about 84% concerning the coronary heart disease and a specifity of about 93%. In the same test persons the ECG after work showed a sensitivity of about 84% and a specifity of about 57%. Dipyridamol test and bicycle ergometry are methods of the same value for the preinvasive diagnostics of the coronary heart disease which should supplement each other. The higher specifity of the ECG changes in the Dipyridamol test was evident in comparison to the bicycle ergometry. In 85 of our patients the Tl-201-scintigraphy was carried out under Dipyridamol and ergometer stress. For the Tl-201-scintigraphy under Dipyridamol a sensitivity of about 70% and a specifity of about 81,5% was the result. In the Tl-201-scintigraphy under ergometer load a sensitity ob about 84% and a specifity of about 57% was the result. The proportion of exactly positive findings increased with the number of the stenosed vessels under ergometer as well as Dipyridamol intervention. A negative load scintigraphy does not exclude a coronary heart disease, but renders a three-vessel-disease very improbable.

Angina Pectoris↗

[Ergometry in childhood. Normal values and use in paediatric cardiology (author's transl)].

In children with congenital heart disease ergometry may be used to measure cardiovascular performance capacity as well as to obtain detailed studies of the functional capacity of different aspects of the cardiovascular system by measuring various parameters during exercise and, thus, rendering a more complete preoperative or postoperative evaluation and possibly contributing to establishment of an indication for surgery. The direct method for measuring cardiovascular performance capacity is the determination of aerobic capacity. All indirect methods such as the W170 (the physical working capacity at a heart rate of 170 beats/min) permit only a rough estimation of working capacity. Since reliable normal values for aerobic capacity of representative samples of boys and girls in different age groups have not been rigidly established, plausible standard values have been estimated in relation to sex, age and body height from previously published data. Subsequently, maximal values for cardiac output have been calculated for all age groups based on a maximal arteriovenous oxygen difference of 13.5 ml/100 ml and, based on a mean maximal heart rate of 200 beats/min, the respective values for stroke volume during exercise have been calculated. In consideration of the fact that equal percentages of aerobic capacity correspond to equal values of arteriovenous oxygen difference, relationships between oxygen uptake and cardiac output were derived for boys and girls of different age groups. The respective regression lines run parallel to a regression valid for male adults which was derived from the values of Ekblom et al. [7] and is based on the formula Q[l/min] = 5.1 + 5.8 VO2[l/min]. In order to permit comparison independent of sex and age, the cardiac output values at rest and during exercise were corrected by subtracting the respective age-related intercepts. The resulting regression line representing normal values independent of sex and age has the formula: Qcorr[l/min] = 5.8 VO2[l/min]. Of particular clinical relevance in these young patients is that the question of feasibility of participation in school physical education classes can generally be answered. Children with congenital heart disease incurring severe hemodynamic compromise have frequently undergone corrective surgery in the pre-school age and the functional results can be assessed accordingly; in children with cyanotic heart disease in whom either no surgery or only a palliative procedure has been performed, ergometry may document severe hemodynamic derangement in spite of a seemingly bland history.

Adolescent↗

Continuous recording of intra-arterial blood pressure during graded bicycle ergometry and stair climbing in essential hypertension.

Ambulatory intra-arterial blood pressure monitoring was used to record blood pressure during graded exercise on a bicycle ergometer and during stair climbing in 6 normotensive subjects, 19 patients with untreated uncomplicated hypertension and 8 patients with untreated hypertension and ECG evidence of left ventricular hypertrophy. Exercise was performed on the bicycle ergometer at 250, 400, 700 and 1,000 kpm/min and each subject also climbed a maximum of 160 stairs. Bicycle ergometry was associated with an increase in systolic and diastolic blood pressure, and in patients with uncomplicated hypertension the levels of pressure attained were high. Stair climbing produced an increase limited mainly to systolic blood pressure, and in some subjects was followed by a secondary increase in both systolic and diastolic pressure during the recovery period. The blood pressure response to bicycle ergometry and stair climbing was generally similar in normotensive and hypertensive subjects but the increase in pressure was greatest in the patients with uncomplicated hypertension.

Adolescent↗

VersaClimbing elicits higher VO2max than does treadmill running or rowing ergometry.

Collegiate varsity oarswomen and coxswain (N = 11) completed maximal aerobic exercise tests on a treadmill, a rowing ergometer, and a simulated climbing machine. Successful completion of each test was evidenced by a plateau in oxygen consumption in response to increasing work rates. VO2max (l.min-1), and minute ventilation (VE, l.min-1) at VO2max were significantly greater (P < 0.05) during simulated climbing compared to treadmill running and rowing ergometry. Maximal heart rate (beats.min-1) was significantly greater (P < 0.05) during climbing and running than during rowing. Findings indicate that progressive, incremental, whole-body climbing exercise elicits significantly greater VO2max values for collegiate oarswomen and coxswain than does graded treadmill running or progressive rowing ergometry.

Adult↗

The accuracy of the ACSM and a new cycle ergometry equation for young women.

The purpose of this study was to determine the accuracy of the American College of Sports Medicine's (ACSM) equation for estimating the oxygen cost of exercise performed by women on a cycle ergometer. Sixty healthy, young females performed a five-stage submaximal cycle ergometry test. Results indicated the SEE for the predicted oxygen values ranged from 79-156 ml.min-1, with total errors (E) ranging from 107-275 ml.min-1. Correlations between the actual and predicted values ranged from r = -0.22 to r = 0.38. The r, SEE, and E were 0.96, 118, and 172, respectively for all of the power loads combined. A revised equation was developed based upon the actual VO2-power relationship. This equation appears as: VO2 (ml.min-1) = kgm.min-1 x 1.6 ml.min-1 + ((3.5 ml.kg-1.min-1 x kg body weight) + 205 ml.min-1). Cross validation was performed on an independent sample of 40 subjects. All of the SEE and E were lower and all of the correlations were higher at each power load in the validation sample. Since the revised equation is based on an actual VO2-power relationship, it would appear that it provides a more accurate depiction of the cycle ergometry VO2-power relationship for women. These facts support its use.

Adult↗

Validation of a cycle ergometry equation for predicting steady-rate VO2.

The purpose of this study was to validate an equation used for predicting the oxygen cost of leg cycle ergometry. This equation was previously shown to be more accurate than the one of the American College of Sports Medicine (ACSM) and appears as: VO2 (ml.min-1) = kgm.min-1 x 1.9 ml.min-1 + ((3.5 ml.kg-1.min-1 x kg body weight) + 260 ml.min-1). Fifty healthy males, ages 18-38 yr old, performed a six-stage (0, 180, 360, 540, 720, and 900 kgm.min-1) submaximal cycle ergometry test while their oxygen uptake was measured. Results indicated the standard error of estimate for the predicted oxygen consumption values ranged from 80-156 ml.min-1, with correlations between the actual and predicted values ranging from r = 0.35 to r = 0.67. Total errors ranged from 92-160 ml.min-1. All of the standard errors and total errors were lower and all of the correlations, except one, were higher at each power load in the validation sample than the original sample. These statistics support the generalizability and accuracy of the new equation. It would appear that the new equation may make accurate predictions in independent samples and is more precise than the ACSM equation.

Adult↗

Validation of a cycle ergometry equation for predicting steady-rate VO2 in obese women.

The purpose of this study was to determine the accuracy of equations developed by the American College of Sports Medicine and by Latin et al. (Med. Sci. Sports Exerc. 25:970-974, 1993) for estimating the oxygen cost of cycle ergometry in obese women. Fifty-six deconditioned subjects, aged 23-60 yr, performed a three-stage (0, 50, and 100 W) submaximal cycle ergometry test while their oxygen uptake was measured. Results indicated that the ACSM equation significantly (P < 0.05) underestimated oxygen consumption at all three workloads. The Latin equation, by contrast, correctly predicted oxygen consumption at the 50- and 100-W workloads, although not at 0 load. The mean bias for all three workloads was 287.6 ml.min-1 for the ACSM equation and 58.3 ml.min-1 for the Latin equation. These data suggest that the Latin equation is more accurate than the ACSM formula for estimating oxygen consumption of loaded cycling in obese women. However, caution must be used when attempting to predict the caloric cost of unloaded cycling.

Adult↗

Plasma catecholamines, atrial natriuretic peptide and blood lactate responses during upright bicycle ergometry with incremental steps adapted to individual maximal work capacity.

To assess whether hormone and metabolic responses in an upright bicycle exercise test are equivalent for subjects with different physical characteristics if test duration for reaching individual maximal work capacity (PWCmax) is standardized we investigated plasma catecholamines, human atrial natriuretic peptide (hANP) and blood lactate responses in twenty healthy sedentary subjects. Ten male (38.5 +/- 4.7 yrs) and ten female (34.5 +/- 6.4 yrs) healthy volunteers performed two ergometries, a first one with incremental steps of 25 Watts each for two minutes to determine PWCmax, and a second one with incremental steps of PWCmax/6. According to this definition a test duration of 12 min was attained for all subjects for the second ergometry. The results show that the increase of the rate pressure product (RPP) as an index of relative cardiac work is significantly different between the male and female group in the test with constant 25 Watts steps. But with the modified exercise test RPP/time-slopes are nearly identical, identicating equivalent cardiac work due to gender and body surface. Similar results are obtained for plasma catecholamines, hANP and blood lactate. Mean values did not differ in the modified exercise test between the male and female group either in the sub-maximal range or at PWCmax. In conclusion, our data suggest that in a maximal exercise test with equal test duration, and considering individual physical properties for the calculation of incremental steps hormonal and metabolic responses are equivalent. It seems that the designed, modified exercise test provides inter-individual comparisons at least for these investigated parameters. The test may be helpful if catecholamines, hANP or lactate are used as diagnostic parameters in patients.

Adult↗

[Diagnosis of coronary insufficiency using bicycle ergometry].

The bicycle ergometry has proved as screening test for the diagnostics of the latent coronary insufficiency. Taking into consideration well-known prerequisites, indications, contraindications, the criteria of withdrawal and the ECG criteria in coronary insufficiency own results and experiences from an analysis of 1,000 bicycle ergometries are presented and compared with literary data.

Adult↗

Effect of work rate increment on peak oxygen uptake during wheelchair ergometry in men with quadriplegia.

The purpose of this study was to determine the effect of work rate increment on peak oxygen uptake (VO2 peak) during wheelchair ergometry (WCE) in men with quadriplegia due to cervical spinal cord injuries (CSCI). Twenty-two non-ambulatory subjects (aged 20-38 years) with CSCI were divided into two groups based on wheelchair sports classification (n = 12 for IA group and n = 10 for IB/IC group). Subjects underwent three different, continuous graded exercise tests (spaced at least 1 week apart) on an electronically braked wheelchair ergometer. Following a 3-min warmup, the work rate was increased 2, 4, or 6 W.min-1 for the IA group and 4, 6, or 8 W.min-1 for the IB/IC group. Ventilation and gas exchange were measured breath-by-breath with a computerized system. Repeated-measures ANOVA showed no significant difference among the three protocols for VO2 peak in the IA group (P greater than 0.05). The mean (SD) VO2 peak values (ml.kg-1.min-1) were 9.3 (2.4), 9.4 (3.2), and 8.4 (2.6) for the 2, 4, and 6 W.min-1 protocols, respectively. In contrast, the IB/IC group showed a significant difference among the protocols for VO2 peak (P less than 0.05). The mean (SD) VO2 peak values (ml.kg-1,min-1) were 15.1 (4.0), 14.1 (4.4), and 12.7 (4.0) for the 4, 6, and 8 W.min-1 protocols, respectively. Post hoc analysis revealed a difference between the 4 and 8 W.min-1 protocols. Our results suggest that graded exercise testing of men with quadriplegia due to CSCI, using WCE, should employ work rate increments between 2 and 6 W.min-1 and that work rate increments of 8 W.min-1 or greater will result in an underestimate of VO2 peak.

Adult↗

Relationship between the curvature constant parameter of the power-duration curve and muscle cross-sectional area of the thigh for cycle ergometry in humans.

For high-intensity cycle ergometer exercise, the relationship between power output ( P) and its tolerable duration ( t) has been well characterized by the hyperbolic relationship: ( P- theta;(F)). t=W', where theta;(F) has been termed the "critical power" or "fatigue threshold". The curvature constant (W') reflects a constant amount of work which can be performed above theta;(F), and it may be regarded as a muscle energy store. The relationship of this energy store to muscle mass is not known. Therefore, the purpose of this study was to determine the relationships among W', accumulated peak oxygen deficit (accumulated peak O(2)-deficit), and muscle cross-sectional area (CSA) of the thigh for high-intensity cycle ergometry in humans. A group of 17 healthy male subjects (aged 21-41 years) participated in this study. The theta;(F) and W' of the P- t hyperbolic relationship and the accumulated peak O(2)-deficit was calculated by standard procedures. The CSA of muscle, fat and bone in the right thigh were measured using ultrasonography. The mean (SD) of theta;(F), W', accumulated peak O(2)-deficit, and muscle CSA of the thigh were 200.0 (17.8) W, 12.60 (2.94) kJ, 2.29 (0.41) l, and 185.3 (22.6) cm(2), respectively. The muscle CSA of the thigh was positively correlated with W' ( r=0.59, P<0.01) and with accumulated peak O(2)-deficit ( r=0.54, P<0.05). The relationship between W' and accumulated peak O(2)-deficit also showed a positive correlation ( r=0.63, P<0.005). Our results indicated that W' derived from the P- t hyperbolic curve as anaerobic working capacity is related to the CSA of muscle.

Adult↗

Median power frequency of the surface electromyogram and blood lactate concentration in incremental cycle ergometry.

The electromyogram (EMG) median power frequency of the vastus lateralis and flexor digitorum superficialis muscles was measured in 12 subjects during cycle ergometry with step-wise increasing exercise intensities up to 100% of VO2max. Blood lactate concentration was measured to investigate the relationship between changes in lactate concentration and shifts in the EMG median power frequency of exercising vastus lateralis and non-exercising flexor digitorum superficialis muscles. The results indicated that lactate concentration did not systematically affect median frequency: in spite of a considerable increase in blood lactate concentration, no systematic decrease of the median frequency during exercise was found, either for the vastus lateralis or for the flexor digitorum superficialis muscles. Instead of a decrease of the median frequency during exercise, as seen in isometrical protocols, an increase was seen in most subjects. An interesting finding was a decrease of the median frequency of vastus lateralis muscle during recovery in 8 subjects. The present findings showed that the relationship between EMG frequency decrease, lactate accumulation and fatigue, as observed in isometric protocols, cannot be simply applied to dynamic exercise.

Adult↗

The relationship between preferred and optimal positioning during submaximal cycle ergometry.

This study was designed to determine how changes in oxygen uptake (VO2) and heart rate (HR) during submaximal cycle ergometry were determined by changes in cycle geometry and/or lower-limb kinematics. Fourteen trained cyclists [Mean (SD): age, 25.5 (6.4) years; body mass 74.4 (8.8) kg; peak VO2, 4.76 (0.79) 1 x min(-1) peak] were tested at three seat-tube angles (70 degrees, 80 degrees, 90 degrees) at each of three trunk angles (10 degrees, 20 degrees, 30 degrees) using a modified Monark cycle ergometer. All conditions were tested at a power output corresponding to 95% of the VO2 at each subject's ventilatory threshold while pedalling at 90 rpm and using aerodynamic handlebars. Sagittal-view kinematics for the hip, knee, and ankle joints were also recorded for all conditions and for the subjects' preferred positioning on their own bicycles. No combination of seat-tube and trunk angle could be considered optimal since many of the nine conditions elicited statistically similar mean VO2 and HR values. Mean hip angle (HA) was the only kinematic variable that changed consistently across conditions. A regression relationship was not observed between mean VO2 or HR and mean hip angle values (P > 0.45). Significant curvilinear relationships were observed, however, between deltaVO2 (VO2 - minimum VO2) and deltaHA (mean HA - preferred HA) using the data from all subjects (R = 0.45, SEE = 0.13 1 x min(-1)) and using group mean values (R = 0.93, SEE = 0.03 1 x min(-1)). In both cases deltaVO2 minimized at deltaHA = 0, which corresponded to the subjects' preferred HA from their own bicycles. Thus, subjects optimized their VO2 cost at cycle geometries that elicited similar lower-limb kinematics as the preferred geometries from their own bicycles.

Adult↗

First clinical experience with an automatic control system for rotary blood pumps during ergometry and right-heart catheterization.

BACKGROUND: At present, most clinically implanted rotary blood pumps are operated at constant speed and adjusted by the physician. It is generally assumed that an adaptation of pump speed to the patient's physiologic requirements would be beneficial. The data provided in this paper, based on hemodynamic and spirometric data during exercise in which a pre-load-sensitive control was used, lend quantitative support to this assumption. METHODS: An automatic speed control was developed and implemented with Matlab on a dSpace controller board. The system uses pump speed, pump power, and pump flow as its only input signals. It was connected to the clinical hardware of the DeBakey VAD System. The control is pre-load-sensitive and uses an expert system to detect excessive unloading and eventual suction. This system was used to quantify the cardiovascular reaction of patients to both automatically controlled and constant pump speed. A sub-group of 5 patients underwent bicycle ergometry with Swan-Ganz catheterization and spiroergometry. RESULTS: The automatic, closed-loop speed control showed robust and stable performance. It provided an increase in pump flow (+0.94 +/- 0.5 liters/min, p < 0.05) compared with constant-speed mode in response to physical activity. Pulmonary arterial (PAP) and capillary wedge pressure (PCWP) clearly decreased (-7.4 +/- 4.1 mm Hg for PAP and -8.3 +/- 4.2 mm Hg for PCWP, p < 0.05), and venous oxygen saturation moderately increased (+5.2%). CONCLUSION: An automatic speed-control system for rotary blood pumps was developed and demonstrated by spiroergometry to be appropriately responsive to physiologic demand.

Algorithms↗