The man behind the eponym. Giulio Bizzozero and his son Enzo.
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This report traces the life of Pierre Masson and mentions some of his investigations. It summarizes Masson's seminal descriptions of glomus tumor and hémangioendothéliome végétant intra-vasculaire (intravascular papillary endothelial hyperplasia), also known as Masson's pseudoangiosarcoma and the Masson lesion. Finally, we reprise Masson's view of the origins of melanocytic nevi and mention Masson's neuronevus. The literature on these subsequent to Masson's articles is not discussed.
Richard L. Sutton described what he termed "periadenitis mucosa necrotica recurrens," now known as major aphthosis or Sutton's ulcer in 1911. He described "leukoderma acquisitum centrifugum" (halo nevus, Sutton's nevus) in 1916. Here, we summarize the 2 publications by Sutton, trace his life story, and comment briefly on these 2 diseases.
This historical review will summarize the report of Francis Senear and Barney Usher on a disease that they called pemphigus erythematodes and which later became pemphigus erythematosus (the Senear-Usher syndrome). It will then outline the lives of these two men. Finally, it will review the literature on that condition and relate the views of various authorities as to whether pemphigus erythematosus is merely pemphigus foliaceus, a variant of pemphigus foliaceus, a syndrome combining features of lupus erythematosus and pemphigus or whether pemphigus erythematosus (Senear-Usher syndrome) is a distinct and separate disease.
In 1948, Lauren V. Ackerman described a neoplasm of the oral mucous membrane, which he thought represented a unique type of squamous cell carcinoma and that is now termed verrucous carcinoma of Ackerman. "Verrucous carcinoma" has also been used as a generic term under which are placed giant condyloma of Buschke-Loewenstein and carcinoma cuniculatum. This report will synopsize the life of Lauren Vedder Ackerman, review the original and subsequent report by Ackerman, and discuss some other reports of oral verrucous carcinoma. Because this review is directed to histopathologists, the histopathology will be emphasized. Other aspects of the neoplasm (eg, clinical picture, incidence, etiopathogenesis, and treatment) will not be discussed, or if so, only briefly. Giant condyloma acuminatum of Buschke-Loewenstein and carcinoma cuniculatum and studies that mention the occurrence of Ackerman's verrucous carcinoma in the pharynx, larynx, and esophagus will be mentioned only in the section on classification.
In a series of papers from 1938 to 1949, Albert Sézary, a French dermatologist and syphilologist, described erythroderma with cellules monstrueuses (monster cells) in the skin and blood, which is now known as Sézary syndrome or Sézary disease. This historical note reprises the life and work of Sézary. It outlines his original reports and his thoughts about the pathogenesis of the disease as a reticulosis, and lists a composite classification of the reticuloses, which includes that of Sézary. We touch briefly on the articles that first used the terms Sézary reticulosis and Sézary syndrome and the changing concepts of the reticuloses and the reticuloendothelial system. We conclude that Sézary syndrome (Sézary disease, Sézary reticulosis) cannot be separated from mycosis fungoides clinically, histopathologically, hematologically, or viscerally and, therefore, is not a disease sui generis. Despite our conclusions, present day consensus defines Sézary disease clinically as a generalized pruritic erythroderma: histopathologically with an epidermal and dermal infiltrate, lymphadenopathy and visceral involvement all containing monster cells (Lutzner/Sézary cells) in the skin, peripheral blood, lymph nodes, and viscera, a disease different and separate from mycosis fungoides.
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