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PubMedDate not supplied

[Does human distomiasis due to Fasiola gigantica exist in the delta of the Niger river in Mali? (apropos of a serological survey)].

Finding of specific anti-Fasciola antibodies in persons living in the central area of the delta of Niger shows that human fascioliasis is a reality in Mali. Fasciola gigantica, the single species affecting livestock is probably the parasite concerned. We think that this parasitic disease in humans is underestimated, obscured by schistosomiasis which is hyperendemic in the country. Complementary studies are much needed for better identification of the problem.

Adolescent↗
PubMed1986

[Unusual echographic aspects of hepatic distomiasis].

The authors report, a pediatric case of hepatic fascioliasis with an unusual ultrasonographic aspect; that is a hypoechoic intrahepatic nodule with an extrahepatic prolongation through a thickened capsule. This ultrasonographic appearance, which has not been reported in the literature to our knowledge, seems to reflect the parasite migration.

Child↗
PubMed1985

[IgE antibodies in human Fasciola hepatica distomiasis].

In patients infected by Fasciola hepatica, total IgE and specific IgE antibodies have been determined by radioimmunoassays, and IgG, IgA, IgM levels by radial immunodiffusion test (Mancini, 1965). Moreover, total and specific IgE levels have been related to parasite egg burden, age, clinical features and eosinophilia. Elevated total IgE and specific IgE antibodies levels have been found respectively in 76% and 48% of the patients whereas there was no significant variations in other immunoglobulins levels. However, though the amount of total and specific IgE was lower than in other helminthic diseases, it appears to be a significant data of the immune response to parasites as it has been reported and discussed previously. It has been shown a significant relationship between total and specific IgE levels, the number of lines by immunoelectrophoresis, and the results of the indirect haemagglutination and indirect fluorescent antibody techniques; each method appeared to be in equal value to perform the early diagnosis of human Fasciola hepatica. In addition, specific IgE antibodies levels were correlated with eosinophilia specially when it exceeds 15%. This results demonstrate the availability of their measurement in the diagnosis of fascioliasis versus other diseases with marked eosinophilia.

Eosinophilia↗
PubMed1985

[Epidemiologic data on distomiasis due to Fasciola gigantica Cobbold on the island of Madagascar. Infestation of cattle between 1975 and 1981].

Stools examinations of zebus were made in Madagascar between 1975 and 1981 for determining the importance of Fascioliasis gigantica in the six provinces of the island during this time. High percentages of F. gigantica eggs were found in the stools of the different infected zebus-herds of five provinces. No fasciolid infection was noted in 1979 in the cattle of the province of Diego-Suarez. Differences were noted between the infection rate obtained by fecal examination and the rate indicated in the veterinary reports. The significance of these results is discussed.

Animals↗