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Results for “DIGITALIS GLYCOSIDES”

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[Mechanism of action of digitalis glycosides].

It appears well established that the inotropic effect of digitalis is due initially to inhibition of the sodium pump (Na-K-ATPase), initiating a cascade effect which in turn increases "diastolic" intracellular Ca2+, which then increases "systolic" intracellular Ca2+ responsible for the inotropic effect.

Calcium↗