Orbital entomophthoramycosis in an infant: recovery following surgical debridement, combination antifungal therapy and use of hyperbaric oxygen.
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Zoosporic and conidial fungi species and environmental factors in 5 various sites of the Podlasie stretch of the river Bug were studied. Samples of water were collected in October 1999 and April 2000 for hydrochemical analysis and the order to determine the number of fungal species. Buckwheat-seeds, hemp-seeds, cellophane and snake exuviae were used as bait during the exposure in laboratory. Sixty-four zoosporic fungus species and forty-six conidial species were found in various sites of the Podlasie stretch of the river Bug. 8 species were recorded for the first time from Poland.
Zoosporic and conidial fungi species and environmental factors in 10 various sites of River Narew in the Narew National Park were studied. Samples of water were collected in autumn 1999 and spring 2000 for hydrochemical analysis and the order to determine the number of fungal species. Buckwheat-seeds, hemp-seeds, cellophane and snake exuviae were used as bait during the exposure in laboratory. 198 lower aquatic fungus species were found in various sites of River Narew. 13 species were recorded for the first time from Poland.
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Conidiobolomycosis is a subcutaneous mycosis of the facial midline affecting primarily adult males. It is caused by the saprophytic fungus, Conodiobolus coronatus, present in soils and dried vegetables, characteristic of intertropical regions. C. coronatus belongs to the class Zygomycetes, order Entomophthorales; it is a fungus composed of thick, short hyphae that grows at temperatures between 30 degrees C and 37 degrees C and causes nasal granulomas. The histologic findings are described of a case of conidiobolomycosis in a 31-year-old male, born and resident in the Urabá region of Colombia. He presented with a mid-facial deformity of the nose and upper lip edema, and polypoid images in the maxillary sinuses with destruction of the nasal septum. The biopsy revealed a diffuse inflammatory lesion located in the deep dermis and in the hypodermis corresponding to a necrotizing granuloma. Associated eosinophils and the presence of the Splendore-Hoeppli phenomenon were noted in the vacant central zone which apparently corresponded to location of the fungal hyphae. They did not stain with HE stain, but reacted to the PAS and Grocott staining techniques and appeared as rigid, thick-walled hyphae, centrally twisted and with cone-shaped endings.
Subcutaneous mycoses caused by the family Entomophthoraceae is very rare type of disease and is being reported sporadically from various Tropical countries including India. Here we report 8 cases of rhinoentomophthoromycosis caused by Conidiobolous coronatus and 7 cases of chronic subcutaneous phycomycosis caused by Basidiobolus ranarum. Cases were detected during a span of 9 years between 1991 to 1999, from 9 districts in and around Kolkata (Eastern India). Former type of lesions were detected among 20 to 65 age group of healthy individuals, predominantly males (7:1). In the latter type, male-female ratio was 2:5, and except for one all cases belonged to below 20 years age group of healthy individuals. Several cases were detected only after examination of repeat biopsy samples. With high degree of clinical suspicion, right approach is needed for laboratory confirmation of diagnosis.
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