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A comparative analysis of R-R intervals distribution parameters in ECG histograms (modal value, moda amplitude, variation range) in 60 healthy individuals as well as in 35 patients with schizoaffective disorders (ICD-10: F 25.1) was performed. These ECG parameters reflected sympathic and parasympathic influences of vegetative nervous system on the cardiac rhythm. Histograms of RR-intervals distribution parameters had been significantly changed in patients during schizoaffective symptoms development as compared to control group: modal value was shifted toward short interval area, moda amplitude was rised, variation range was narrowed. It means the increasing sympathic influence and decreasing parasympathic nervous system activity. The alternation trend was the same in patients with the prevalence of affective symptoms (affectdominant form of schizoaffective psychosis) or with paranoid predominance (schizodominant form of schizoaffective psychosis). The intensity of these changes was more expressed in patients with affectdominant form of schizoaffective psychosis.
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The authors studied the cardiac rhythm regulation status in 22 patients with chronic noncalculous cholecystitis, 35 patients with chronic calculous cholecystitis and 31 patients with chronic hepatitis. All the patients showed signs of sympathicotonic type of regulation of cardiac rhythm. Upon receiving propranolol (0.04), 67.8% of patients displayed no vegetative regulation, with 3.2% cases demonstrating a paradoxical trend of vegetative reactions.
Lead is a metal widely spread in the natural environment. It is strongly toxic, particularly to the peripheral and central nervous systems. The toxic influence on the cardiovascular system is most pronounced in case of higher exposures, where myocardium and the renal circulation are affected, in consequence of which secondary arterial hypertension can develop. It seems that lead affects the cardiovascular system mainly by changing the peripheral autonomic nervous system and leading to chronic neuropathy. Chronic exposure, even to low doses of lead, can impair conduction in myocardium. In order to assess those changes thoroughly prospective studies involving newly employed workers with occupational exposure to toxic activity of lead will be necessary.
AIM: To assess femoston effects on the cardiovascular system in postmenopause. MATERIAL AND METHODS: Cardiovascular effects of femoston were studied in 20 postmenopausal women with menopausal syndrome. 70% patients had arterial hypertension. Cardiovascular system was examined before the treatment and after three treatment months using 24-h monitoring of arterial pressure, echocardiography, photoplethysmography, conjunctival biomicroscopy, central hemodynamics tests. RESULTS: In the course of femoston treatment menopausal manifestations relieved, arterial pressure was lowering. 3-month treatment has improved parameters of central and peripheral hemodynamics: total peripheral vascular resistance significantly fell, stroke and minute blood volumes, cardiac indexrose, tissue blood flow and microcirculation improved. CONCLUSION: Femoston produces positive changes in cardiovascular system, vascular tone, microcirculation and arterial pressure.
The cardiovascular system is a common target of amyloidosis. This review presents the current clinical and diagnostic approach to amyloidosis, with the emphasis on cardiovascular involvement. It summarises recent nomenclature, classification, and pathogenesis of amyloidosis. In addition, non-invasive possibilities are discussed, together with endomyocardial biopsies in the diagnosis of cardiac amyloidosis. Finally, recent advances in treatment and prognostic implications are presented.