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PubMedDate not supplied

Computer courses in the undergraduate nursing curriculum in Turkey.

This study surveys computer courses in undergraduate nursing schools in Turkey. To accomplish this, the investigator gave an assignment to first-year students at the Ege University School of Nursing as part of a computer course in 2003-2004. The assignment consisted of having students use their computer skills and do research on the Internet to obtain information about computer classes at other Turkish nursing schools. The objective of this assignment was to correspond by e-mail with first-year students at these institutions. Because of this assignment, at least 70 contacts were established, and information has been exchanged between nursing students at 45 different universities in Turkey. This study shows that one method used by undergraduate nursing schools in Turkey to educate their students in modern nursing practices is to integrate computer courses in their curricula, thereby providing students important practical technology skills.

Adaptation, Psychological↗

PubMed2001

Update on the development of emergency medicine as a specialty in Turkey.

Emergency medical care, both prehospital and hospital-based, is currently provided by general practitioners in over 90% of the emergency departments in Turkey. In the early 1990s, government and university leaders recognized that Turkey needed to improve its emergency medical care system, and they chose to adapt the mature and tested Anglo-American model of emergency medicine (EM). EM was declared to be an independent specialty by the Ministry of Health in 1993. The first paramedic school and the first EM residency programme (36 months in length) were opened at the Dokuz Eylul University in 1993 and 1994, respectively. In 1995, the Emergency Medicine Association of Turkey (EMAT) was established. Today, there are 14 EM residency programmes around the country, and these are trying to design a common curriculum. The connection between departments is improving with annual meetings organized by EMAT. In addition, EMAT is developing international collaboration in the Middle East region. The Turkish government is trying to promote EM specialist physicians and paramedics in the national emergency care system.

Curriculum↗

PubMed2006

Characterization of bovine and human group B streptococci isolated in Turkey.

In the study, group B streptococci (GBS) isolated from bovines and humans in and around Van, eastern Turkey, were serotyped, and their haemagglutination and lectin-agglutination properties were also determined. This study is the first epidemiological survey of GBS serotypes performed in Turkey. A total of 148 GBS isolates, 76 from bovine milk and 72 from women attending a maternity polyclinic, were examined by co-agglutination, slide haemagglutination and slide lectin-agglutination tests. By the co-agglutination test, 34 (44.7%) of bovine isolates and 49 (68%) of human isolates could be serotyped. In bovine isolates, type VII (11.8%), III (10.5%), Ic (6.5%) and VIII (3.9%) were the most frequently detected serotypes. The most frequent human serotypes were Ic (33.3%), IV (8.3%), VIII (6.9%), V (5.5%) and R (5.5%). In the haemagglutination test using rabbit erythrocytes, 23 (33.3%) bovine and 15 (23.4%) human isolates were found to be positive. The bovine GBS isolates showed a significant positive agglutination reaction with Dolichos biflorus lectin (30.4 %), whereas the human GBS isolates were found to be positive for Arachis hypogea (18.8%) and Canavalia ensiformis (37.5%) lectins. The treatment of GBS with trypsin was also found to be important for the demonstration of the haemagglutination and lectin-agglutination properties of GBS. The results of the study provide data on serotype distribution and the formulation of a possible GBS vaccine in Turkey, and the lectin-agglutination tests may also be useful for differentiating bovine and human GBS strains.

Agglutination Tests↗

PubMed1992

Structure determination of turkey egg-white lysozyme using Laue diffraction data.

The three-dimensional structure of turkey egg-white lysozyme (TEWL) has been solved and refined at 2.5 A resolution using X-ray data collected by the Laue method. This is the first protein structure determination undertaken using Laue diffraction data. A re-examination of the existing structure of TEWL was necessary when attempts to refine an atomic model based on the C alpha positions in the Protein Data Bank (entry 1LZ2) failed. The correct orientation and position of the turkey lysozyme molecules within the crystallographic unit cell were determined by molecular replacement using a refined model of the homologous hen egg-white lysozyme crystal structure. After modification of the model to reflect the differences in amino-acid sequence between the chicken and turkey enzymes, the structure was subjected to crystallographic refinement using the simulated-annealing refinement technique and conventional least-squares refinement. This yielded a final residual of R = 20.7%. This crystal form is of potential interest for time-resolved crystallographic studies since the amino-acid residues involved in catalysis (Asp52 and Glu35) are accessible to solvent and not blocked by crystal contacts.

Animals↗

PubMed1997

The prevalence of allergic diseases in primary school children in Edirne, Turkey.

BACKGROUND: Allergic diseases present a major health burden for children as shown by the rising morbidity and increased mortality from asthma. Information on the prevalences of allergic disorders and contributing factors as well will help to establish feasible measures to change this trend, and more efficient assignment of the limited health resources. OBJECTIVE: To assess the prevalences of asthma and other allergic diseases and the contribution of various risk factors in primary school children in Edirne, Turkey. METHODS: Children aged 7 to 12 in primary schools in the municipality and 24 villages of Edirne were surveyed via a questionnaire completed by the parents. The cumulative (lifetime) and current (last 12 months) prevalences of allergic diseases and the presence of passive smoking, atopic family history, animal contact and breast-feeding in infancy were determined. RESULTS: A total of 5412 children (70.1% from the metropolitan and 29.9% from the rural area) were enrolled. The cumulative and current prevalences of all allergic diseases were 24.6% and 9.9% respectively. The cumulative (lifetime) prevalences of bronchial asthma, wheezing, allergic rhinitis and atopic dermatitis were 16.4%, 18.9%, 12.3% and 2.2%, and the current (last 12 months) prevalences were 5.6%, 5.8%, 4.5% and 0.9% respectively. Three-fourths of the children were exposed to tobacco smoke at home. Atopic heredity appeared the most prominent risk factor for any allergic disorder. Neither age, breast-feeding nor place of habitation affected the occurrence of allergic disorders. Animal contact was a significant risk factor for asthma and wheezing (adjusted odd ratios (OR) and 95% confidence intervals (CI) for current prevalences are 1.38 (CI = 1.04-1.83) and 1.35 (CI = 1.02-1.78) respectively), exposure to indoor tobacco smoke for wheezing (OR = 1.52, CI = 1.10-2.09), and male gender for asthma (OR = 1.50, CI = 1.16-1.93). Current prevalences for all allergic diseases were significantly lower than those previously reported in Ankara, Turkey. CONCLUSIONS: Allergic diseases are a major health burden for primary school children in Edirne, Turkey. Although atopic heredity appears to be the foremost important risk factor, reduction of exposure to indoor tobacco smoke and animal contact, especially for those with atopic family history, are important preventive measures. The impact of environmental exposures on distinguishing prevalences of allergic diseases in Ankara and Edirne should be further investigated.

Asthma↗

PubMed1984

Adrenocorticotropin. 57. Synthesis and biological activity of ostrich and turkey hormones.

Synthesis of ostrich and turkey corticotropin (ACTH) has been accomplished by the solid-phase method. Each was identical to the natural hormone in high performance liquid chromatography. Relative potencies in a lipolytic assay in isolated rabbit fat cells were: human ACTH, 100; ostrich ACTH, 53; turkey ACTH, 28. In isolated rat fat cells relative lipolytic potencies were: human ACTH, 100; ostrich ACTH, 2; turkey ACTH, 13. It was concluded that lipolytic potency is sensitive to alterations in structure throughout the entire length of the ACTH sequence in the rat fat cell assay.

Adipose Tissue↗

PubMed1990

[The growth of the skeleton, body mass and muscle fiber diameter of the turkey (Meleagris gallopavo) from hatching to the 224th day].

Growth of body mass, femur, tibiotarsus, and tarsometatarsus length as well as the diameter of muscle fibers in the M. pectoralis were measured in (Large White) female turkeys between birth and day 224. Growth-specific approximations were established with the Janoschek function as modified by Sager (1978) and with the Logistic function. While the Janoschek function fairly described the growth of the turkey, the Logistic function throughout gave beginning values that were too high and theoretical end values that were too low. Of the five growth parameters that were measured, the diameter of the muscle fibers showed its maximal rate of growth first on day 21. The following decrease in growth rate took the following sequence: length of tarsometatarsus, femur, and tibiotarsus, diameter of muscle fibers, body mass. 99% of growth had occurred in the tarsometatarsus length on day 109, femur length on day 117, tibiotarsus length on day 138, diameter of muscle fibers on day 166, and the body mass on day 231. A comparison of this growth with that of other domestic fowl showed close relationships between the way turkeys and chickens grow.

Animals↗

PubMed2006

Effects of glypican-1 on turkey skeletal muscle cell proliferation, differentiation and fibroblast growth factor 2 responsiveness.

The heparan sulfate proteoglycan, glypican-1, is a low affinity receptor for fibroblast growth factor 2 (FGF2). Fibroblast growth factor 2 is a potent stimulator of skeletal muscle cell proliferation and an inhibitor of differentiation. Heparan sulfate proteoglycans like glypican-1 are required for FGF2 to transduce an intracellular signal. Understanding the role of glypican-1 in the regulation of FGF2-mediated signaling is important in furthering the understanding of the biological processes involved in muscle development and growth. In the current study, a turkey glypican-1 expression vector construct was transfected into turkey myogenic satellite cells resulting in the overexpression of glypican-1. The proliferation, differentiation, and responsiveness to FGF2 were measured in control and transfected cell cultures. The overexpression of glypican-1 in turkey myogenic satellite cells increased both satellite cell proliferation and FGF2 responsiveness, but decreased the rate of differentiation. The current data support glypican-1 modulation of both proliferation and differentiation through an FGF2-mediated pathway.

Animals↗

PubMed2005

Effects of giardiasis on school success, weight and height indices of primary school children in Turkey.

BACKGROUND: Giardia intestinalis, the most common parasite in the world, causes several adverse effects on school children, with the prevalence rate ranging between 7.3% and 28% (mean 13.8%) in Turkey. The aim of the present study was to investigate possible adverse effects of G. intestinalis on success at school, and the mean weight and height of primary school children in Sivas, Turkey. METHODS: Five primary schools from central Sivas, Turkey, had a number of students from different socioeconomic conditions and regions. The stool specimens were examined by light microscopy for giardiasis using saline-Lugol and/or zinc sulfate flotation method. Three groups in the present study include the symptomatic giardiasis group (SG), which included children with giardiasis along with abdominal pain and/or diarrhea, the asymptomatic giardiasis group (ASG) without any symptom and the non-parasitic (NPG) group without any parasites. RESULTS: While 599 (34.6%) out of 1730 children were parasitic, 192 (11.1%) had only G. intestinalis. Ninety-eight (5.7%) of 192 were SG (with diarrhea and/or abdominal pain and 94 (5.4%) were ASG. The weights and heights were lower in the children with giardiasis than the children without any parasite. There was a significant difference between the giardiasis group and NPG when the numbers of persons living in the house were compared. While there were no significant difference between the giardiasis group and NPG when the sexes were compared, success at school and economical levels were found to be significantly different between these groups. CONCLUSION: There was a higher prevalence of giardiasis in primary school children and their physical and mental conditions were affected adversely. Giardia infections in particular have adverse effects on success at school.

Body Height↗

PubMed2006

Intervention studies for prevention of pressure ulcers in Turkey: a literature review.

AIM: To examine critically the literature published in the Turkish language (1955-2004) related to risk assessment tool(s), their application to nursing care and prevention of pressure ulcers (PrUs). Specific objectives were to identify the advantages of risk assessment and prevention of PrUs in hospital; to establish the most valid and reliable methods available to evaluate the effectiveness of PrU prevention programmes; to determine methodological problems encountered by researchers and explore how these were overcome; and to present the findings so they could be used to develop a valid and reliable audit tool based upon the empirical evidence. METHODS: All journals and convention booklets published in Turkey related to nursing between the years 1955-2004 were examined. Because many journals in Turkey are not yet available by electronic means, the published Turkish articles were all examined by hand. A total of 3031 articles in 17 nursing journals and 36 congress books (convention booklets) were examined. Five articles were found to meet the study criteria and were taken into the study and evaluated. CONCLUSION: There is a need to determine valid and reliable assessment methods, and the results need to be recorded on standard forms. In addition, it is important to increase the motivation of nursing personnel who give direct patient care to use the tools available in order to prevent the development of PrUs. From the review findings it is apparent that in Turkey, there is a dearth of research evidence upon which to base practice in the sphere of PrU prevention, and further research is urgently required.

Humans↗

PubMed1996

Refugees of Turkish origin: "coerced immigrants" to Turkey since 1945.

"While several studies (in both Turkish and English) have been made on migration to the Ottoman Empire from the Caucasus and the Balkans during the nineteenth century...very little systematic and comprehensive research on migration has been undertaken on the period since the establishment of the Turkish Republic. This article, which aims to partially fill the gap, is divided into three parts: the issue of national refugees (refugees of Turkish origin) in relation to Turkey's overall refugee policy; Turkey's policy towards national refugees; and the volume and causes of refugee migration to Turkey since 1945." (SUMMARY IN FRE AND SPA)

Asia↗

PubMed2006

Seroprevalence of herpes simplex virus type 1 and type 2 in Turkey.

BACKGROUND: Herpes simplex virus (HSV) infections are among the most common infectious diseases in humans. The prevalence of herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) varies widely across the world. HSV-2 infection is the primary cause of genital herpes. It is highly prevalent in human populations in many parts of the world, and is the most common cause of genital ulcer disease worldwide. In spite of the large prevalence and growing incidence of herpes simplex infection (HSV-1 and HSV-2), relatively few data have been published regarding the seroprevalence of herpes simplex infection, while no data exist regarding the Turkish population. METHODS: We aimed to investigate the prevalence of HSV-1 and HSV-2 in selected populations in Turkey. A cross-sectional study was conducted involving 2082 serum samples of 725 adults, 300 pregnant women, 200 blood donors, 483 sex workers and 110 patients with genital warts and 264 hotel staff in Istanbul, Turkey. All serum samples were assessed for HSV1 and HSV-2 IgG antibodies using an HSV-type specific, enzyme-linked immunosorbent assay (ELISA). RESULTS: The prevalence of HSV-2 and HSV-1 antibodies was 4.8 and 85.3% in sexually active adults; 5.5 and 96% in blood donors; 5 and 98% in pregnant women, 17.3 and 93.6% in patients with genital warts; 8.3 and 97.3% in hotel staff; and 60% and 99% in sex workers. CONCLUSION: These results confirm a higher prevalence of HSV infection than estimated, especially in high risk groups in Turkey. The high prevalence of HSV infection underlines the need for education among these populations.

Adolescent↗

PubMed1980

Effects of feeding schedules on diurnal periodicity of Leucocytozoon smithi gametocytes in the peripheral blood of domestic turkeys.

Eighteen domestic turkeys naturally infected with Leucocytozoon smithi Laveran & Lucet were maintained on restricted feeding schedules under conditions of either continuous light or natural light (light 13 h:darkness 11 h) photoperiods. Peripheral gametocyte numbers of L. smithi in all turkeys were determined every 2 h over a 36-h period. Peripheral gametocyte numbers of turkeys maintained under continuous light and restricted to either a 10-h feeding period (9:30 p.m. to 7:30 a.m.) once a day or a 2-h feeding period twice a day (7:30 a.m. to 9:30 p.m. and 7:30 p.m. to 9:30 p.m.) increased at or near the time of feed availability. Under natural photoperiod, gametocyte periodicity was not affected by restricting feed availability to the dark phase of the light-dark cycle. Mean parasite numbers were highest during the light phase when feed was not available, and lowest during the dark period when feed was accessible.

Animals↗

PubMed2004

Financing of dental services in Turkey: opinions and expectations of dentists, residents, and patients.

OBJECTIVES: This study investigates the attitudes of dentists, residents, and patients on the financing of dental services in Turkey. METHODS: In this descriptive study, randomly selected groups of 860 dentists, 641 patients, and 866 residents from 9 provinces of Turkey were interviewed. Their agreement on various statements on financing issues of dental services were recorded and analyzed. RESULTS: Eighty-two percent of the dentists, 83.8 percent of the patients, and 76.4 percent of the residents agreed that "governments should finance all dental services." The majority of the dentists (83.6%), patients (74.7%), and residents (84.4%) stated that patients should pay a copayment for their dental treatment. CONCLUSION: Survey results indicate that the current financing system of dental services in Turkey is not satisfactory either for the providers or for the users.

Adult↗

PubMed2026

Serotypic and Genomic Diversity of Vibrio anguillarum in Rainbow Trout Farms in Turkey: Implications for Vibriosis Control and Vaccine Candidate Selection.

Outbreaks of vibriosis caused by Vibrio anguillarum are a persistent constraint on rainbow trout (Oncorhynchus mykiss) aquaculture. However, information on the population structure of field strains in Turkey has been lacking. Here, we report the first systematic serotypic, proteomic, and genomic characterization of 23 V. anguillarum isolates collected over 10 years from rainbow trout farms located in six major aquaculture regions of Turkey. Serological analyses based on microagglutination, supported by ELISA characterization of hyperimmune sera, identified a clear predominance of serotype O1, whereas isolate V12 exhibited a non-agglutinating, atypical O-antigen profile. Protein profiling (SDS-PAGE) and immunoblotting showed largely conserved whole-cell protein patterns among the isolates, but distinct immunogenic bands at 14, 18, and 40 kDa were detected in isolates V18 and V21. Long-read whole-genome sequencing revealed that most Turkish isolates grouped within the global O1 clade, while V12, V25, and V28 isolates occupied more distant branches. Comparative genomics demonstrated a conserved core virulence gene set (RTX toxins, siderophore and iron-uptake systems, motility and adhesion factors, Type VI secretion system), with strain-dependent variation in accessory loci such as anguibactin and T6SS-I. Experimental infections of rainbow trout demonstrated significant differences in virulence among isolates (p < 0.05), with the V18 isolate showing high, the V15 intermediate, and the V12 low-mortality rates. By elucidating the relationship among the serotype, immunogenic protein profiles, virulence gene repertoires, and in vivo pathogenicity, this study provides a comprehensive overview of the antigenic and genomic diversity of Vibrio anguillarum isolates from Turkey. Notably, the identification of V18 and V21 as promising candidate strains for further vaccine evaluation, characterized by high virulence and unique immunogenic features, provides a scientific foundation for the development of serotype-specific vaccination strategies to mitigate vibriosis-associated losses in aquaculture.

Animals↗

PubMed1989

Sodium lactate delays toxin production by Clostridium botulinum in cook-in-bag turkey products.

Comminuted raw turkey, containing 1.4% sodium chloride, 0.3% sodium phosphate, and 0 (control), 2.0, 2.5, 3.0, or 3.5% sodium lactate, was inoculated with a 10-strain mixture of proteolytic type A and B Clostridium botulinum spores. The inoculated turkey was vacuum packaged and cooked by immersion in heated water to an internal temperature of 71.1 degrees C. Samples were incubated at 27 degrees C for up to 10 days. Five samples per treatment were examined for botulinal toxin at specific intervals. Sodium lactate exhibited an antibotulinal effect which was concentration dependent. Processed turkey containing 0, 2.0, 2.5, 3.0, or 3.5% sodium lactate was toxic after 3, 4 to 5, 4 to 6, 7 or 7 to 8 days, respectively. Subsequent studies with a broth medium revealed that lactate, not the sodium ion, was the principal factor in delaying botulinal-toxin formation.

Animals↗

PubMed2001

Prevalence of Campylobacter spp., Escherichia coli, and Salmonella serovars in retail chicken, turkey, pork, and beef from the Greater Washington, D.C., area.

A total of 825 samples of retail raw meats (chicken, turkey, pork, and beef) were examined for the presence of Escherichia coli and Salmonella serovars, and 719 of these samples were also tested for Campylobacter spp. The samples were randomly obtained from 59 stores of four supermarket chains during 107 sampling visits in the Greater Washington, D.C., area from June 1999 to July 2000. The majority (70.7%) of chicken samples (n = 184) were contaminated with Campylobacter, and a large percentage of the stores visited (91%) had Campylobacter-contaminated chickens. Approximately 14% of the 172 turkey samples yielded Campylobacter, whereas fewer pork (1.7%) and beef (0.5%) samples were positive for this pathogen. A total of 722 Campylobacter isolates were obtained from 159 meat samples; 53.6% of these isolates were Campylobacter jejuni, 41.3% were Campylobacter coli, and 5.1% were other species. Of the 212 chicken samples, 82 (38.7%) yielded E. coli, while 19.0% of the beef samples, 16.3% of the pork samples, and 11.9% of the turkey samples were positive for E. coli. However, only 25 (3.0%) of the retail meat samples tested were positive for Salmonella. Significant differences in the bacterial contamination rates were observed for the four supermarket chains. This study revealed that retail raw meats are often contaminated with food-borne pathogens; however, there are marked differences in the prevalence of such pathogens in different meats. Raw retail meats are potential vehicles for transmitting food-borne diseases, and our findings stress the need for increased implementation of hazard analysis of critical control point (HACCP) and consumer food safety education efforts.

Animals↗

PubMed2004

Development of a nucleoprotein-based enzyme-linked immunosorbent assay using a synthetic peptide antigen for detection of avian metapneumovirus antibodies in Turkey sera.

Avian metapneumoviruses (aMPV) cause an upper respiratory tract disease with low mortality but high morbidity, primarily in commercial turkeys, that can be exacerbated by secondary infections. There are three types of aMPV, of which type C is found only in the United States. The aMPV nucleoprotein (N) amino acid sequences of serotypes A, B, and C were aligned for comparative analysis. On the basis of the predicted antigenicity of consensus sequences, five aMPV-specific N peptides were synthesized for development of a peptide antigen enzyme-linked immunosorbent assay (aMPV N peptide-based ELISA) to detect aMPV-specific antibodies among turkeys. Sera from naturally and experimentally infected turkeys were used to demonstrate the presence of antibodies reactive to the chemically synthesized aMPV N peptides. Subsequently, aMPV N peptide 1, which had the sequence 10-DLSYKHAILKESQYTIKRDV-29, with variations at only three amino acids among aMPV serotypes, was evaluated as a universal aMPV ELISA antigen. Data obtained with the peptide-based ELISA correlated positively with total aMPV viral antigen-based ELISAs, and the peptide ELISA provided higher optical density readings. The results indicated that aMPV N peptide 1 can be used as a universal ELISA antigen to detect antibodies for all aMPV serotypes.

Animals↗