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At least 1,243 records · Page 69Linked to original sources
PubMed1983

Fractures of the central and third tarsal bones in horses.

The case histories and follow-up data for 11 horses with slab fractures of the central or 3rd tarsal bones were examined for information pertaining to the diagnosis, which was difficult to identify, treatment, which was proven ineffective, and the prognosis, which was shown to be poor for return to racing. The purpose of the study was to define the results that could be obtained by nonoperative methods, in an attempt to determine whether surgical treatment was advisable. Nine of the horses were Standardbreds and 2 were Thoroughbreds; all horses were 2 to 4 years old and were being exercised at race speed when the injury occurred. The diagnosis usually was made at the referral examination, some time after injury. Distention of the tibiotarsal joint usually developed following fracture of the central tarsal bone. In some fractures, local anesthetic injection or multiple radiographic views were required for diagnosis. Not all fracture planes were demonstrable radiographically. Prolonged rest was ineffective in restoring athletic soundness. Lag screw fixation was used in 1 horse, the only horse in the series that raced successfully after injury.

Animals↗
PubMedDate not supplied

Skeletal abnormalities in domestic chicken.

In 14,891 necropsies performed on domestic poultry during January 1976 to October 1977, two cases of skeletal abnormalities were found. One was a tarsometatarsal spur in an adult female chicken, and the other was a crossed-beak associated with microphthalmia.

Animals↗
PubMed1982

Relationship of complement to experimental arthritis induced in rats with streptococcal cell walls.

Experimental arthritis developed in rats injected intraperitoneally with aqueous suspensions of peptidoglycan-polysaccharide complexes (PG-APS) isolated from group A streptococcal cell walls. Reduction of serum complement by pretreatment with cobra venom factor (COV) reduced acute joint inflammation over the first 3 days following injection of PG-APs. Thereafter, the course of the disease was not different in the COV-treated rats. The serum levels of complement were depressed below detectable levels by 24 hr in rats injected only with cell walls, but rebounded to normal levels or above 3 days after injection. In rats injected with COV before cell walls, the complement levels also increased 3 days after injection of cell walls, in contrast to sustained depressed levels in rat injected only with COV. The correlation between severity of joint inflammation and serum complement levels at day 3 was positive in COV-treated rats. The quantity of cell wall per joint at day 3 correlated with the severity of joint disease. However, COV treatment did not alter the amount of cell wall localized in joint tissue. Therefore, although complement does appear to have a role in early joint inflammation, its effect is not upon the transport of cell wall into joint tissue.

Animals↗
PubMedDate not supplied

Osseous development and tibial dyschondroplasia in five lines of turkeys.

Tibiotarsi and femurs from five genetic lines of turkeys from 8 to 39 weeks of age were examined to define the characteristics of normal bones. Bone lengths and body weights are presented. Tibial dyschondroplasia (TD) frequently was detected on gross examination and by high-detail radiography. The incidence of TD peaked at 12 weeks of age, when 79% of the toms were affected. This incidence rate dropped until the age of closure of the proximal tibial physis (22 to 24 weeks in toms) but remained 5 to 15%. Deformities of the tibiotarsi were frequently associated with TD in older toms. The incidence of TD and tibiotarsal deformities was highest in toms of the heaviest line.

Age Factors↗
PubMed1995

Alteration of spleen lymphocyte populations in rats with arthritis induced by muramyl dipeptide analogue or complete adjuvant.

To examine the involvement of lymphocytes in the development of MDP-Lys(L18)-induced arthritis (MIA) in rats and the exacerbation of MIA by cyclosporin A (CsA), we analysed the spleen lymphocyte subset using monoclonal antibodies and flow cytometry during the development of arthritis and compared the results with those found in adjuvant-induced arthritis (AIA). Subcutaneous injection of MDP-Lys(L18) 4 mg/kg to male Lewis rats for 14 days caused very slight and quite clear increases in tarsal joint thickness on days 8 and 15, respectively. This increase was significantly enhanced by co-administration of CsA 10 mg/kg on both of these days. Adjuvant intracutaneously injected once increased the thickness only on day 15, and this was completely inhibited by CsA. The populations of CD4+ and CD8+ cells were increased and decreased, respectively, increasing the CD4+/CD8+ ratio, from day 8 in MIA. CsA enhanced the MDP-Lys(L18)-induced changes in these populations and caused additional decreases in the number of CD5+ cells. Only the CD4+ cell population was increased on day 15 in AIA, and this increase was inhibited by CsA. These results suggest that the spleen lymphocyte subsets in MIA have a different role from those in AIA, and that the contribution of enhancement of the subset changes to the exacerbating effect of CsA on MIA.

Acetylmuramyl-Alanyl-Isoglutamine↗
PubMed1994

Serum- and bone-mineral status of ostriches with tibiotarsal rotation.

Tibiotarsal rotation in ostrich chicks is a serious problem that accounts for considerable financial loss to ostrich farmers. Serum- and bone-mineral analyses of 20 ostrich chicks with tibiotarsal rotation were compared with serum- and bone-mineral analyses of eight normal ostrich chicks of comparable age, sex and body mass, and raised under identical conditions. The serum-zinc values were significantly higher and the bone-calcium and phosphorus values significantly lower in the affected group than in the group of normal ostrich chicks. The results indicated poor mineralization of bone with subsequent reactive osteoid formation.

Animals↗
PubMed1995

Tourniquet-induced hypertension in an ostrich.

Surgery was performed on a 3-year-old 110-kg male ostrich (Struthio camelus) to remove a sequestrum from the dorsal aspect of the left tarsometatarsal bone. A pneumatic tourniquet was positioned proximal to the surgical site and inflated to 600 mm of Hg. Systolic blood pressure increased 35% over 105 minutes while the tourniquet was inflated. Systolic blood pressure decreased 31.5% within 30 seconds after removal of the tourniquet pressure. Recovery from anesthesia and surgery was routine. The tourniquet-induced hypertension in this ostrich was similar to that reported for human beings and horses.

Animals↗
PubMed1995

Influence of radiographically detectable orthopedic changes on racing performance in standardbred trotters.

The tarsocrural, metacarpophalangeal, and metatarsophalangeal joints of 753 Standardbred yearlings were radiographed. On the basis of radiographic findings, the horses were allotted into 4 groups. Group-1 horses had osteochondrosis in the tarsocrural joints. Group-2 horses had palmar/plantar bony fragments in the metacarpo- and metatarsophalangeal joints. Group-3 horses had radiographic changes in the metacarpo- and metatarsophalangeal joint region, such as bony fragments located at the dorsoproximal end of the proximal phalanx, osteochondrosis of the sagittal ridge of the third metacarpus/metatarsus, ununited proximoplantar tuberosity of the proximal phalanx, or nonarticular, osteolytic and productive changes in the proximal sesamoid bones. Group-4 horses did not have radiographic changes. The number of race starts and race earnings (categorized) of the horses in groups 1, 2, and 3 were compared with those of the horses in group 4, using a multivariate regression analysis. Horses in groups 1, 2, and 3 had significantly fewer starts and somewhat lower earnings compared with the horses in group 4.

Animals↗