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Tourism's impacts on natural resources: A positive case from China.

Tourism development may result in negative impacts on natural resources owing to overuse and mismanagement. However, tourism may also play positive roles in natural resource conservation, which has rarely been verified in practice, although some researchers have demonstrated this in theory. In this article, taking the Jiuzhaigou Biosphere Reserve as a case study area, we conducted an analysis for the environmental impacts from tourism development based on social survey and interpretation of remote sensing images. The results show that the natural environment was not degraded and some indicators are even improving because all the residents have participated in tourism and given up farming and hunting. It is concluded that it is possible to use tourism as a way to balance natural resource conservation and economic development under the preconditions of making effective policies to encourage and help local people participate in tourism business and to benefit from it.

China↗

Urbanization and the loss of resource lands in the chesapeake bay watershed.

We made use of land cover maps, and land use change associated with urbanization, to provide estimates of the loss of natural resource lands (forest, agriculture, and wetland areas) across the 168,000 km2 Chesapeake Bay watershed. We conducted extensive accuracy assessments of the satellite-derived maps, most of which were produced by us using widely available multitemporal Landsat imagery. The change in urbanization was derived from impervious surface area maps (the built environment) for 1990 and 2000, from which we estimated the loss of resource lands that occurred during this decade. Within the watershed, we observed a 61% increase in developed land (from 5,177 to 8,363 km2). Most of this new development (64%) occurred on agricultural and grasslands, whereas 33% occurred on forested land. Some smaller municipalities lost as much as 17% of their forest lands and 36% of their agricultural lands to development, although in the outlying counties losses ranged from 0% to 1.4% for forests and 0% to 2.6% for agriculture. Fast-growing urban areas surrounded by forested land experienced the most loss of forest to impervious surfaces. These estimates could be used for the monitoring of the impacts of development across the Chesapeake Bay watershed, and the approach has utility for other regions nationwide. In turn, the results and the approach can help jurisdictions set goals for resource land protection and acquisition that are consistent with regional restoration goals.

Agriculture↗

Privileged knowledge and social change: effects on different participants of using geographic information systems technology in natural resource management.

The use of geographic information systems (GIS) technology in natural resource management has expanded rapidly: It is the preferred tool of spatial data analysis addressing large landscapes and is typically the presentation medium for conveying landscape-scale scientific findings to all kinds of audiences. In a case study using the Coastal Landscape Analysis and Modeling Study in western Oregon, it was found that the use of GIS to analyze and display natural resource data in that project produced a variety of responses among different participants and participant groups. The findings offer insights into the workings of groups attempting public involvement in natural resource management.

Conservation of Natural Resources↗

Early development of systems analysis in natural resources management from man and nature to the miami conservancy district.

Contemporary approaches to natural resources and environmental decision-making typically draw on a "systems" perspective to assess and improve management strategies. This paper describes the early genesis of the systems analysis approach. It concentrates on a period between the mid-19th to early 20th centuries. During the early part of this period, George Marsh's Man and Nature and related works laid out an approach to problem-solving that recognized the relationship among physically disperse elements in the environment, the need to balance benefits against costs, the potential for using quantitative modeling to understand management options, and the importance of integrating human and natural components into solutions. In the early 20th century, the Miami Conservancy District project brought this approach to fruition with its use of complex simulation and optimization modeling, detailed cost-benefit analysis, and its linking of economics, engineering, science, and law into a far-reaching solution to a complex water resources problem. The objective of this paper is to describe the early development and application of this conceptual approach to problem-solving. An examination of the origins of natural resources systems analysis can broaden one's perspective of the contemporary field to understand its roots as a philosophy for environmental problem-solving.

Conservation of Natural Resources↗

Mechanical ventilation in critically ill cancer patients: outcome and utilisation of resources.

Intensive care is increasingly being used in the management of cancer patients. It is important that a disproportionate share of special care resources is not expended on futile care of terminally ill patients. A requirement for mechanical ventilation has been stated to affect survival in cancer patients. The objectives of this study were to determine our hospital utilisation of ICU facilities and the prospects of a successful outcome in cancer patients with a need for ventilatory support. The Norwegian Radium Hospital is a 400-bed cancer hospital with a 12-bed combined postoperative and intensive care unit (PO/ICU). For each patient admitted to the PO/ICU, patient data including diagnosis, therapeutic interventions, use of resources and outcome are entered in a computerised database. We reviewed all 10,051 patients admitted during a 5-year period, focusing on the patients receiving ventilatory support. There were 347 patients who were treated with mechanical ventilation, 228 patients only for a short period postoperatively after extensive surgery. A further 119 patients (mean age 68 years, mean SAPS 33.5) were treated with mechanical ventilation for more than 24 h or died during treatment in the ICU; 65 patients (55%) were admitted after elective surgery, 24 (20%) after surgical emergencies and 30 (25%) after medical emergencies. Metastatic disease was present in 59% of them. These 119 patients comprised 1.18% of all patients admitted to the PO/ICU, but utilised 28% of all resources. They included 34 patients (29%) who died during the ICU stay, while 69 patients (58%) were still alive after 6 months. The ICU mortality in different groups was: surgical patients 24%, gynaecological patients 9%, oncological patients 63%. The mortality in the age group >70 years was 15%. The role of ICU facilities, including mechanical ventilation, is important for optimal supportive care in cancer patients. Our results indicate that this treatment modality should not generally be restricted in critically ill cancer patients. The quality of life of the patients who survived should be of interest to those involved in further medical and ethical decisions concerning the level of care in the ICU.

Adolescent↗

Resource implications of febrile neutropenia in cancer patients. An international collaborative study.

No previous study has compared countries with respect to differences in clinical practice and resource use of cancer patients with febrile neutropenic episodes (FNE). The purpose of this international, cross-sectional pilot study conducted in tertiary care centers across Europe, Brazil and Australia was to evaluate the resource use attributable to febrile neutropenia in different countries. A total of 17 centers from eight countries provided 128 patients. The leading malignant disorders were hematological malignancies (n = 47), lymphomas (n = 27), and breast cancer (n = 26). The median length of duration of FNE was 4 days (interquartile range, 3-8). The incidence density of antimicrobial exposure was 4.691 days of antimicrobial therapy per 1,000 days of FNE. There were 23 patients who received a total of 280 days of G-CSF therapy. On average, 5 (+/-5.4) blood samples per patient were drawn and cultured. The most common diagnostic radiographic test was the chest X-ray, with a total of 224 such examinations performed in 82 patients. We conducted an international cross-sectional study on resource implications of febrile neutropenia in cancer patients. The records of the febrile neutropenic patients included in this study reflect clinical practice in a heterogeneous, international patient population, treated with modern supportive care and early empiric antibiotics by clinicians at different levels of expertise.

Adult↗

The contribution of Acadia PRIMENet research to science and resource management in the National Park Service.

Acadia National Park was one of the 14 sites included in the Park Research and Intensive Monitoring of Ecosystems network (PRIMENet). For eight years the EPA monitored ultraviolet (UV) radiation at this site, with the National Park Service (NPS) sponsoring a total climate and air monitoring station. Under the auspices of PRIMENet, research projects were initiated that investigated the effects of UV on amphibians, determined watershed mass balances, and developed a model of deposition along an elevational gradient. The monitoring data and research results have been used by park management to protect vegetation and water resources from ozone and deposition. These data are now being used to develop a "vital signs" monitoring program under the NPS' Inventory and Monitoring Program. These data sets have been used in regional, national and international programs to protect human health and resources from air pollution. Public outreach has been accomplished through web site resources and via the Schoodic Education and Research Center.

Air Pollution↗

Equity, access and resource allocation: planning hospital services in New Zealand.

The desire to limit the growth of expenditure in the Western world has seen increased attempts to reallocate resources in the name of equity and efficiency. This paper reviews recent moves in New Zealand to achieve an equitable financing and distribution of hospital resources. While a more equal distribution of resources is likely to result from the recent reforms, redistributive policies of the type being implemented in New Zealand, which leave the basic structure of the health care system intact, may have only a marginal impact on improvements in access to care and health status.

Cost Control↗

Medicinal plant genetic resources and international cooperation: the Brazilian perspective.

Brazil is a gene rich country, host to 24% of known primate species, between 10 and 15 million species of insects, and 22% of the world's higher plant species. The debate over how and by whom these resources should be protected has intensified over the last few years due to a growing awareness of the links between sustainable utilization of natural resources, conservation of biodiversity, and economic development. Within this context the pharmaceutical exploitation of natural products for drug development has a prominent place. For a significant portion of Brazilian society, fair cooperation is welcome and can facilitate drug discovery. Nevertheless, the complexity of the consequences of patenting and utilization of natural resources calls for a thorough cost/benefit analysis in order to promote policies that can ensure significant and long term benefits for the country.

Brazil↗

Allocation of critical care resources: entitlements, responsibilities, and benefits.

Determination of allocation of limited critical care resources appears to be an inevitable development. Criteria proposed to assign such limited resources among patients are not defined. It has been argued that allocation of critical care resources could be based on the principals of patient entitlements to health care, responsibilities of the physician to the critically ill patient, and beneficence. However, based on an analysis of the philosophical tenants of the Hippocratic Oath, there is little to support the concept of "sin" taxes or patient triage on the basis of judgment on the moral merit of the patient.

Critical Care↗

Survey of California emergency departments about practices for management of suicidal patients and resources available for their care.

STUDY OBJECTIVE: To determine the resources available and current practices for the treatment of patients with suicidal ideation or attempts in California emergency departments (EDs). METHODS: We conducted a mail and e-mail survey of the directors of all 346 EDs in the state of California. Data collected included identification of hospital and respondent, type of hospital, presence of separate psychiatric ED, total number of ED patients and number of ED patients with suicidal ideation or attempts who were treated per week, mental health personnel on call to evaluate suicidal patients, criteria for patient disposition, available disposition options, delays in patient care, changes desired in the ED treatment of suicidal patients, and adequacy of community resources for suicidal patients. RESULTS: Two hundred twenty-three of 346 (64.5%) ED directors responded to the survey. Overall, the mean estimate of the proportion of ED visits by suicidal patients was 1.7%. Though evaluation of patients with suicidal ideation by a mental health professional was the usual practice, 51 respondents (23%) reported that they occasionally send patients with suicidal ideation home without such an evaluation, and 8.5% reported this was done more than 10% of the time. No single type of mental health professional, including psychiatrist, social worker, county or private psychiatric evaluation team, psychiatric nurse, or psychologist, was available for evaluation of suicidal patients in more than 50% of respondent EDs. In the majority of EDs, psychiatric evaluations were performed by either mobile county or private psychiatric evaluation teams or social workers on call to the ED. Psychiatrists were reported to evaluate the majority of suicidal patients in only 10% of EDs. Only 27% of respondents had the ability to admit patients to a psychiatric service at their hospital. When patients needed to be transferred, the estimated mean wait for these transfers was 7 hours. Seventy-one percent of respondents reported needing improved access to mental health personnel for evaluation of suicidal patients; 61% reported needing improved access to mental health personnel for patient disposition. CONCLUSION: In California EDs, there are limited mental health services for suicidal patients. Regional solutions to emergency and nonemergency mental health problems are needed, including improved access to mental health personnel for ED evaluation, disposition, and follow-up of suicidal patients and community mental health resources for patient referrals.

Adolescent↗

Remote consultations and HIV/AIDS continuing education in low-resource settings.

BACKGROUND: Telemedicine is a way to support physicians working in resource-poor settings, providing remote consultations and continuing medical education on HIV/AIDS care. METHODS: A hybrid E-mail/web support telemedicine service was created in 2003 at the Institute of Tropical Medicine, Antwerp, Belgium, with a discussion forum hosting more than 170 healthcare professionals from 40 different countries, generally resource constrained. Interesting posts and recurring questions from this discussion forum have been elaborated as case studies or frequently asked questions, available on the website for consultation. Education and support are also provided through interactive quizzes, user-friendly guidelines, and policy documents with a particular focus on HIV/AIDS care in developing countries. RESULTS: From April 2003 to March 2005, 342 questions were sent from over 17 countries in Africa, Asia, and South America. The vast majority of these questions (93%) were patient-oriented, with only 7% being general questions. Of the patient-oriented questions, 49% were related to antiretroviral therapy, and 44% were related to the diagnosis and treatment of opportunistic infections. CONCLUSIONS: Telemedicine is a cheap and effective method of providing clinical support and continuing education to healthcare workers treating HIV-positive patients in resource-poor settings.

Developing Countries↗

Multi-criteria natural resource management with preferentially dependent decision criteria.

The traditional assumption with multi-criteria natural resource management models is that the values of the decision alternatives with respect to one criterion can be assessed independently of the values of the decision alternatives with respect to other criteria. In practice, however, the assumption of independent decision criteria is not always realistic. For example, the importance of the amount of old forests to biodiversity may depend on the amount of dead wood. This paper shows how multi-criteria natural resource management problems can be analysed in a case involving dependent decision criteria. The proposed models are based on pair-wise comparisons of items in the ratio scale and statistical regression analysis of the pair-wise comparisons data. The basic idea behind the dependent models is to ask the decision maker (e.g. forest owner) to assess the decision alternatives or their characteristics simultaneously with respect to dependent decision criteria. The separate models for discrete and continuous cases are given, which enable the number of potential management alternatives to vary from a few to infinite. The models proposed allow a more realistic description of the decision problem in multi-criteria natural resource management.

Biodiversity↗

Long-term dynamics in land resource use and the driving forces in the Beressa watershed, highlands of Ethiopia.

Land degradation in the Ethiopian highlands is considered to be one of the major problems threatening agricultural development and food security in the country. However, knowledge about the forces driving the long-term dynamics in land resources use is limited. This research integrates biophysical information with socio-economic processes and policy changes to examine the dynamics of land resource use and farmers' livelihoods in the Beressa watershed for over 40 years during the second half of the 20th century. It was found that there have been substantial dynamics in land resource use in the area. The natural vegetation cover has been extensively cleared, although most of the cleared areas have since been replaced with plantations. Grazing land has expanded remarkably at the expense of cropland and bare land. However, the expansion of cropland was minimal over the 43-year period despite a quadrupling of the population density. Yields have not increased to compensate for the reduction in per capita cropland, and the soil quality appears to be not that good. Though the farmers perceived it otherwise, the long-term rainfall pattern has improved. In response to soil degradation, water shortage, socio-economic and policy changes, farmers have tended to gradually change from annual cropping to tree planting and livestock production to cope with the problems of soil degradation, water scarcity and smaller farms. Income diversification through the sale of wood and cattle dung is becoming a major livelihood strategy. Apparently, however, little attention has been paid to investments in soil and water conservation (SWC) and local soil fertility amendments. In particular, increased erosion and related high nutrient losses in sediments, as well as the removal of potentially available soil nutrients through the sale of manure threatens to damage agricultural sustainability in the area.

Agriculture↗

Country development does not presuppose the loss of forest resources for traditional medicine use.

There are challenges in using ethnobotany as a research technique. Foremost, there is a generational loss of traditional medicine knowledge and a loss of plant resources as raw material for medicinal use. These losses are frequently attributed to the development and modernization of cultures. However, recent work has reported that the loss of languages, a classic marker of traditional knowledge, does not correlate with the relative development status of a country. By analyzing datasets regarding the relative development status of countries and land use patterns, I show that the loss of natural resources for traditional medicine use does not correlate with the relative development status of a country. This work implies that with proper governance, it is possible for countries to develop while preserving the natural resources utilized in traditional medicine.

Conservation of Natural Resources↗

Resource use of elderly emergency department patients with alcohol-related diagnoses.

This study evaluates resource use associated with alcohol-related admissions through the emergency department (ED) by older adults. Data from 11 states were extracted from the Healthcare Cost and Utilization Project State Inpatient Databases. The study results revealed that the presence of a secondary alcohol-related diagnosis significantly increased resource use (37-119% for length of stay and 126-343% for charges; p < .05) associated with the top 10 International Classification of Diseases, Ninth Revision, Clinical Modification Clinical Classifications Software diagnoses. They also showed that admissions with an alcohol-related primary diagnosis had lower associated charges (2,172 dollars; p < .05) and longer lengths of stay (0.3 days; p < .05) than other types of ED admissions. Proper linkages to substance abuse treatment services should be instituted and coupled with medical treatment to limit the additional resource use burden of alcohol-related admissions.

Age Factors↗

Optimal conservation strategy in fluctuating environments with species interactions: resource-enhancement of the native species versus extermination of the alien species.

Alien species are often a major threat to native species. We consider optimal conservation strategies for a population whose viability is affected both by an alien species (such as a competitor, a predator, or a pathogen) and by random fluctuations of the environment (e.g. precipitation, temperature). We assume that the survivorship of the native population can be improved by providing resources such as food and shelter, and also by an extermination effort that decreases the abundance of the alien species. These efforts decrease the extinction probability of the native population, but they are accompanied by economic costs. We search for the optimal strategy that minimizes the weighted sum of the extinction probability and the economic costs over a single year. We derive conditions under which investment should be made in both resource-enhancement and extermination, and examine how the optimal effort levels change with parameters. When the optimal strategy includes both types of efforts, the optimal extermination effort level turns out to be independent of the density and economic value of the native species, or the variance of the environmental fluctuation. Furthermore, the optimal resource-enhancement effort is then independent of the density of the alien species. However, the parameter dependencies greatly change if one of the efforts becomes zero. We also examine the situation in which the impact of the alien species is uncertain. The optimal extermination effort increases with the uncertainty of this impact except when the cost of extermination is very high.

Animals↗

DORSSAA: Drug-Target interactOmics Resource Based on Stability/Solubility Alteration Assay.

Advancements in high-throughput techniques such as Thermal Proteome Profiling and the high-throughput Proteome Integral Solubility Alteration assay have revolutionized our understanding of drug-protein interactions. Despite these innovations, the absence of an integrative platform for cross-study analysis of stability and solubility alteration data represents a significant bottleneck. To address this gap, we introduce Drug-target interactOmics Resource based on Stability/Solubility Alteration Assay (DORSSAA), an interactive and expandable web-based platform for the systematic analysis and visualization of proteome stability and solubility alteration assay datasets. Currently, DORSSAA features 1,135,985 records spanning 38 cell lines and organisms, 135 compounds, and 40,742 protein targets. Through its user-friendly interface, the resource supports comparative drug-protein interaction analysis and facilitates the discovery of actionable therapeutic targets. Through two case studies, methotrexate target profiling in A549 cells and combinatorial-therapy drug-target interactions in leukemia cell lines, we demonstrate DORSSAA's utility for identifying protein-drug interactions across diverse experimental contexts. This resource empowers researchers to accelerate drug discovery and enhance our understanding of protein behavior. Compared with data repositories and interaction databases, DORSSAA provides direct protein-level evidence of mechanisms of action with strict statistical control for each study. This enables more reliable identification of drug targets, off-target effects, and potential drug combinations.

Humans↗