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Hierarchical classification and the integration of self-structure in late adolescence.

A number of empirical studies have demonstrated that one's self-concept is multi-dimensional in nature, varies according to social context, and shows increased differentiation throughout adolescence. There has been relatively less work, however, examining the integration of multi-dimensional social selves. Rosenberg and Gara's (1985) model of the multidimensional self (a model that utilizes a statistical procedure called "hierarchical classification" or HICLAS) was employed to investigate the integration of social selves during late adolescence. First- and fourth-year college students (n=128) completed a computer program designed to collect data required to construct HICLAS "self-structures". The findings indicated that the social selves of fourth-year college students were more related conceptually and were more differentiated than the social selves of first-year students. The differences between first- and fourth-year students suggested that hierarchical classification procedures could be used to address developmental hypotheses.

Adolescent↗

Clinical consequences of the EI/MCS "diagnosis": two paths.

There are two distinct paths down which patients "diagnosed" with environmental illness/multiple chemical sensitivities (EI/MCS) can travel. Along the first path, beliefs about low-level, multiple chemical sensitivities as the cause of physical and psychological symptoms are instilled and reinforced by a host of factors including toxicogenic speculation, iatrogenic influence mediated by unsubstantiated diagnostic and treatment practices, patient support/advocacy networks, and social contagion. Intrapsychic factors also reinforce this path through the motivational mechanism of factitious malingering, or unconscious primary and secondary gain, mediated through psychological defenses, particularly projection of cause of illness onto the physical environment. The second path involves restructuring distorted beliefs about chemical sensitivities. Explanations of the placebo effect, the physiology of the stress response, and the symptoms of anxiety and panic facilitate the direction of EI/MCS patients onto this path. A decision model is presented to discriminate among toxicogenic and psychogenic explanations of the EI/MCS phenomenon, based on appraisal of reaction and physiologic and cognitive responses during provocation chamber challenges under double-blind, placebo-controlled conditions. These studies have been helpful therapeutically for some patients in selecting the path that leads to wellness. This paper suggests how various therapeutic techniques can be employed with difficult patients. Often, supportive psychotherapy establishes a therapeutic alliance which facilitates cognitive therapy to restructure distorted beliefs. In the process of finding alternative explanations to chemical sensitivities, the etiology of symptoms is related to stressful life events, including childhood experiences which may have disrupted normal personality development and coping capacity. Furthermore, biological and physiological sequelae stemming from early, chronic trauma have been identified which could explain many of the multisystem complaints. The incidence of childhood abuse reported by EI/MCS patients is strikingly high, and it is recollection of trauma that many EI/MCS patients avoid by displacing the psychologic and physiologic adults sequelae onto the physical environment. The reenactment of these experiences may be necessary in the therapy of some affected individuals. Despite the significant therapeutic effort expanded, some patients who are imprisoned by a closed belief system about the harmful effects of chemical sensitivities are resigned to travel down the path which ultimately leads to despair and depression, social isolation, and even death.

Child↗

HIV-1 Vpr does not inhibit CTL-mediated apoptosis of HIV-1 infected cells.

HIV-1 infected persons develop a robust CTL response to HIV antigens, yet HIV-1 is able to evade this host response and successfully replicate. The mechanism(s) of evasion is not completely defined but has been suggested to include resistance of infected cells to CTL-mediated apoptosis. The HIV-1 Vpr protein induces G2 arrest by indirectly inhibiting activation of cyclin B/p34cdc2 kinase. Granzyme B, the principle mediator of CTL-induced apoptosis, prematurely activates this same kinase complex. Therefore, we assessed the susceptibility of HIV-1 infected cells to CTL-mediated apoptosis to determine whether the expression of Vpr protected the infected cells from CTL-induced apoptosis. Antigen-specific CD8(+) CTL were able to induce apoptosis in HIV-1 infected cells and cells labeled with peptide corresponding to the CTL epitope with equivalent efficiency. This demonstrates that neither HIV-1 Vpr nor any other HIV protein directly inhibits CTL effector functions. Furthermore, we confirm that HIV-1 Nef is able to provide partial protection from CTL recognition of infected cells. Thus, the inability of CTL to control HIV-1 infection is likely not due to direct inhibition of CTL-mediated apoptosis.

Apoptosis↗

Stressful life events and co-occurring depression, substance abuse and suicidality among American Indian and Alaska Native adolescents.

Depression, suicidality and substance abuse disorders are examined with special emphasis on the role of stressful life events in predicting severity and patterns of comorbidity among American Indian and Alaska Native adolescents in boarding school environments. Both amount and severity of comorbidity increase with age and specific patterns of comorbidity are associated with gender. Different types and amounts of stressful life events predict specific combinations of comorbidity. These outcomes are interpretable with respect to associated cultural dynamics and the ecology of mental health services delivery for Indian and Native adolescents. Theoretical and methodological issues are discussed in relation to the use of stressful life events in examining cultural factors related to comorbidity among culturally different populations.

Adolescent↗

Toxicity of high-dose ifosfamide in children.

Ifosfamide has been shown to be an active agent in the treatment of several childhood cancers. However, the optimal dose and method of administration remains to be established. The dose/response relationship of ifosfamide suggests that a maximum tolerable, fractionated dose be given, and to reduce hospitalisation this dose should be given in the shortest possible time. A total of 20 patients aged 1-23 years received 124 courses (mean, 6 courses/patient; range, 1-16); 9 subjects had either relapsed or resistant disease, and all of these had previously received cyclophosphamide. A dose of 3 g/m2 ifosfamide was given for 2 (five patients) or 3 (15 patients) successive days. In all, 9 patients received the drug twice daily as a bolus and 11 were given a continuous infusion. All patients received 3 g/m2 mesna per day with ifosfamide and for 12 h there after, and hydration was maintained with 3 l/m2 fluid daily. Myelosuppression occurred in all patients but was mild and reversible, with no toxic deaths. On four occasions in three patients treatment had to be delayed due to myelosuppression. Seven episodes of fever and neutropaenia were successfully treated with antibiotics. The mean glomerular filtration rate in 13 patients at the start of treatment was 104 ml/min per 1.73 m2 and at the end was 92 ml/min per 1.73 m2. In all, 19 patients had microscopic and 1 macroscopic haematuria, with no clinical sequelae. Two patients with grossly impaired renal function following previous cisplatin therapy may have been precipitated into terminal renal failure by the ifosfamide therapy. Only one person developed neurotoxicity, which recurred on further treatment with ifosfamide but was fully reversible. All patients had moderate to severe vomiting, which was controlled with anti-emetics. No abnormalities of liver or cardiac function were detected. We conclude that ifosfamide given by this schedule is safe in patients with normal renal function.

Adolescent↗

[Influence of actual epileptic seizures on performance and personality in epileptic children (author's transl)].

A test battery was administered to 108 brain-damaged epileptic backward children. The purpose of the investigation was to examine the influence of actual seizures (free of seizures or not) on intelligence, visuomotoric gestalt function, sensoric motoric function and personality characteristics. The two-failed t-test, discriminant analyses, regression analyses and factor analyses were computed. Most differences in performance (intelligence, visual perception, motoric function) between the diagnostic groups (free of seizures vs. not free of seizures) were statistically significant (P less than 1%); the differences in personality characteristics, however, were not statistically significant (P greater than 1%). The administered tests differentiated the two groups: 90% of the 108 subjects were correctly classified due to a clinical criterion. Motoric and perseverance variables were the most important variables of the discriminant function. Subjects without seizures scored higher than subjects with epileptic seizures. As a result of factor analyses personality variables and performance variables constituted different factors in most cases. An important exception concerning the group "free of seizures" was the variable "Pathognomic verbalization": this variable and performance variables were part of one factor. In subjects "not free of seizures", however, this variable and other personality variables clustered together in one factor.

Adolescent↗

Parental rearing behaviour and personality characteristics of depressed patients.

Within the framework of a large and ongoing study of depression in its biological, clinical, psychological and social aspects, 141 patients of both sexes in the age range 21 to 65 years participated in a study of parental rearing practices and personality characteristics. The perceived parental rearing behaviour was assessed by means of a specially constructed inventory (EMBU), and the personality characteristics by means of a Swedish personality inventory, the KSP, which had previously been shown to measure relatively stable personality characteristics. Several important correlations emerged between parental rearing practices and personality traits. In particular, power assertive practices and psychological types of discipline (shaming, guilt-engendering) showed significant correlations with aspects of aggression and significant negative correlations with socialization. There was a good agreement between male and female patients in the judgement of the rearing behaviour of their fathers. However, female patients scored their mother as more abusive, whereas male patients scored them as more over-protective. On the whole, the rearing practices of the mothers were judged more negatively than those of the fathers. The findings of this study appear to be consistent with earlier results reported by other authors.

Adult↗

Perceived parental behaviour and psychogenic needs.

A new inventory aimed at the assessment of perceived parental rearing practices (EMBU) and an inventory aimed at assessing psychogenic needs (CMPS) were completed by 152 healthy subjects of both sexes (108 males and 44 females). The series was comprised of 73 conscripts, 57 medical students, 15 vocational therapy students and 7 staff personnel who were 17-46 years old. Several significant correlations were found between dimensions of parental rearing behaviour and personality characteristics, most of them being consistent with earlier findings by other authors. Although statistically significant, the correlation coefficients were mostly low, leaving a large amount of unexplained variance. The findings of this study support the general assumption that the perception of parental rearing practices is an important factor in the shaping of personality make-up but that other, still unexplored factors might have an even greater importance in the determination of habitual personality characteristics.

Adolescent↗

Depressive characteristics of sexually abused children.

Allen and Tarnowski (1988) identified a pattern of depressive characteristics that distinguished physically abused from nonabused children. The present study attempted to extend the generality of these findings to sexually abused children. Sexually abused and nonabused children were compared on measures of depression, hopelessness, and self-esteem. Results indicated that while sexually abused children self-reported more depressive symptoms in comparison to nonabused controls, that these differences were not statistically significant and failed to replicate the findings noted for physically abused children.

Child↗

Personal and family distress in homeless adolescents.

Previous research has indicated that homeless children exhibit high rates of behavioral and emotional problems and come from families characterised by conflict and rejection. Further, some evidence exists to show that family variables may relate to adolescent distress differently for homeless males and females. In this study, 117 homeless adolescents were compared to a sample of non-homeless youths on the self reported incidence of personal and family problems. The homeless children reported the highest incidence of all behavioral and emotional problems, parental marital discord, overprotection, and the lowest levels of parental care and acceptance. Sex effects were not evident in reported levels of personal or family problems. However, substantially more variance in the adolescents level of behavioral and emotional disturbance was predictable from family measures for females than males. Overall, the results point to the importance of incorporating family distress models in the understanding and remediation of adolescent homelessness.

Adolescent↗

Life events: children's reports.

Children 7 to 12 years of age were asked to indicate events they had experienced in the previous three months in a questionnaire devised for the study. Most children were able to complete the questionnaire and reported positive and negative events, the most common themes being personal achievement, illness-related events and problems in relationships. The agreement between parents and child reporting of individual events was uneven and children reported more events than parents. Psychiatrically disturbed children noted an excess of negative and loss events and children attending paediatric clinics reported fewer events, particularly fewer positive happenings, than non-attending primary school children. A child Life Events questionnaire may be of use to explore disturbed and ill children's perception of their lives.

Child↗

Perceived parental rearing, depression and coping behaviour. A pilot study in psychiatric patients.

Within the framework of Perris' vulnerability model of psychopathology the relationships between perceived parental rearing and coping behaviour in adulthood have been investigated. Rejecting and punitive rearing practices of both parents seem to contribute to the formation of intrapsychic, emotion-oriented coping strategies. The results indicate that childhood social experiences, in particular, parent-child relations, both directly affect vulnerability to psychopathological manifestations in later life and indirectly influence the conditions through the aquisition of coping strategies.

Adaptation, Psychological↗

Psychopathology in Dutch young adults: enduring or changeable?

This study reports on stability and change in emotional and behavioral problems in young adults over a 2-year time span. A sample of 528 18- to 22-year-olds from the general population was assessed using the Young Adult Self-Report (YASR) on two occasions. Stability coefficients for the total problem score of the YASR were 0.63 for males and 0.75 for females. Forty-nine percent of the subjects who were initially classified as deviant were still deviant at follow-up. Of all YASR syndromes, the highest stability was for the Anxious/Depressed scale.

Adolescent↗

A strengthening experience? Mental distress during military service. A study of Norwegian army conscripts.

Conscription compels 70% of male Norwegians to invest 1 year of their lives in military training. For 19-to 20-year-old men, the military service is an important arena of secondary socialization. In a cross-sectional study of mental health in army conscripts using the 12-item General Health Questionnaire (GHQ), the case prevalence was 48% (cut-off 2/3). This was remarkably high, given that the study population had been screened for mental disease on several occasions, and a large number of recruits with symptoms of mental disease had been excluded before the survey began. Statistical analyses indicated that the high case prevalence was mainly due to situational factors. Four dimensions were identified: (1) social relations with officers, peers and family, (2) structural factors inherent in the system of obligatory military service, (3) the meaningfulness of daily tasks and (4) financial problems. GHQ caseness was statistically associated with physical inactivity and consumption of junk-food, tobacco, alcohol and cannabis. It is concluded that military service in its present form may have undesirable consequences both for civilian society and for military efficiency. Recruits need help to cope with the complex psychosocial and transactional challenges of military service.

Adaptation, Psychological↗

Cigarette smoking, alcohol, and oral contraceptive use by type A adolescent--the Bogalusa Heart Study.

Type A behavior pattern (TABP) is an independent risk factor for cardiovascular (CV) disease and is characterized by hostile, aggressive, competitive behavior. TABP characteristics and CV risk factors have been found in children and adolescents. TABP has been correlated with adult alcohol consumption, but studies associating Type A and smoking are mixed. The purpose of this study is to investigate the smoking, alcohol use, and oral contraceptive use of Type A children and adolescents. The Hunter-Wolf Type A scale and a health habits questionnaire were evaluated for 2092 children, ages 8-17 years, within the context of a comprehensive biracial epidemiological CV screening in Bogalusa, Louisiana. Global Type A and factor components were evaluated: hostility, eagergy, desire for control, drive, and competitiveness. Correlation coefficients reflected the strongest associations between hostility and smoking and between hostility and drinking for white males. The age at menarche appeared to be correlated with the drive component.

Adolescent↗

Heritability of hostility-related emotions, attitudes, and behaviors.

Hostility-related variables have been categorized as to kinds of emotions, attitudes, and behaviors. Relatively few studies have explored whether genetic factors contribute to individual differences in these variables. Moreover, the majority of this research has involved male subjects. The present study utilized the twin method to evaluate the influence of genetic factors on hostility-related emotions, namely, trait anger and irritability, hostility-related attitudes, namely cynical hostility and suspiciousness, and hostility-related behaviors, namely, physical, verbal, and indirect aggression in adult women. Responses on the measure of trait anger showed evidence of significant heritability. However, evidence for a genetic component to responses on the irritability scale was less clear. There was no support for the notion of a genetic component to the measure of suspiciousness, and the evidence of a genetic contribution for cynical hostility was not significant. It was expected that due to environmental influences for women, only certain forms of aggression would show genetic variance, namely, verbal and indirect as opposed to physical forms. The results were generally congruent with these expectations.

Adult↗

Stability of type A behavior during adolescence, young adulthood, and adulthood.

The stability of Type A behavior was studied in 1737 randomly selected adolescents and young adults. The method used was the AFMS questionnaire, which is based on the Matthews Youth Test for Health and a Swedish version of the Jenkins Activity Survey. Results showed that in males Type A behavior remained at the same degree of stability during adolescence, later adolescence, young adulthood, and adulthood. In girls, Type A behavior showed no stability during adolescence, a high stability during young adulthood, and a slightly lower degree of stability in adulthood.

Adolescent↗