Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “MASTECTOMY”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,243 records · Page 69Linked to original sources
PubMed1985

Efficacy of physical therapy for patients who have undergone mastectomies. A prospective study.

This study was undertaken to determine if differences existed between a group of 49 patients who had undergone mastectomies and who received postoperative physical therapy and a group of 41 similar patients who did not. Preoperative and postoperative data were obtained for each patient from goniometric measurements of shoulder abduction, flexion, and external rotation; upper extremity circumferential measurements; and patient self-report on 10 functional assessment items. While age was controlled, an analysis of variance was used to test the effects of physical therapy and the side of surgery in relation to the dominant hand. No clinically significant differences were found between the groups for circumferential data. Goniometric measurements demonstrated that, postoperatively, the group receiving physical therapy had better shoulder range of motion and less difficulty with all functional assessment items. The results suggest that patients receiving postmastectomy physical therapy achieve better functional outcomes than those who do not.

Arm↗
PubMed1996

Kaposi's sarcoma on a lymphedematous arm after mastectomy.

Two patients with Kaposi's sarcoma developing in an area of lymphedematous arm postmastectomy are reported. The Kaposi's sarcoma occurred after latent periods of 26 and 7 years following radical and modified-radical mastectomy, respectively, in the edematous tissue of the ipsilateral arm. The cutaneous nodules were purple in color and ranged in size from a few millimeters to > 1 cm in diameter. The results of routine laboratory tests were all within normal limits. Human immunodeficiency virus (HIV) antibody and cytomegalovirus (CMV) antigen, using enzyme-linked immunosorbent assay (ELISA), were negative.

Aged↗
PubMed1998

Estrogen-receptor status of patients who underwent mastectomy for breast cancer with a disease-free interval of not less than 8 years.

The authors present a series of 1,226 patients who underwent total or partial mastectomy for breast cancer, who for a period of no less than 8 years from surgery did not have a relapse or relapsed only after 8 years. The patients were evaluated for estrogen-receptor (ER) content of the primary tumor. In the group of 237 patients who relapsed, only 8.8% (21 of 237) were ER negative; in the group of 989 patients without a relapse, 24.1% (239 of 989) were ER negative. The difference was significant (p < 0.001). Therefore, the absence of hormone receptors (ER negative) indicates a favorable prognosis after a period of 8 years. For comparison, ER content in the group of patients who relapsed before 8 years was evaluated; the results showed a different prognosis from the ER-negative patients in this group. Because the behavior of ER-negative tumors in the cancer-affected breast is similar to that of non-hormone-dependent carcinomas arising in other parts of the body (which generally are considered cured after a long disease-free interval from surgery), we conclude that this repudiates the theory that confers to breast cancer the character of a systemic disease.

Breast Neoplasms↗
PubMed1999

The safety and efficacy of prophylactic ondansetron in patients undergoing modified radical mastectomy.

UNLABELLED: We aimed to evaluate the antiemetic efficacy, safety, and clinical utility of prophylactic ondansetron administered at the end of the surgery for the prevention of postoperative nausea and vomiting (PONV) in a homogenous population of 54 women undergoing modified radical mastectomy (MRM). A standard general anesthetic and perioperative analgesic technique were used. After surgery, patients received either saline placebo or ondansetron 4 mg IV. Episodes of PONV, as well as rescue antiemetic requirements, were recorded for the first 24 h after surgery. The 24-h incidence of PONV (33.3% vs 81.5%; P = 0.0010) was significantly lower in the ondansetron group. The severity of PONV, evaluated by the number of emetic episodes per patient (1.59+/-1.90 vs 0.29+/-0.66; P = 0.0029), and the rescue antiemetic requirement (59.2% vs 14.8%; P = 0.0019) was significantly lower, in the ondansetron group. Patient satisfaction scores and number needed to prevent PONV (2.07) were significantly better and therapeutically more favorable in the ondansetron group. The incidence of adverse events such as headache, dizziness, and increased liver enzyme levels (number needed to harm = infinity) was similar in both groups. Administered at the end of the surgery in adult female patients undergoing general anesthesia for MRM, ondansetron 4 mg is effective and safe in preventing PONV. We recommend the clinical practice of routine prophylactic ondansetron to prevent PONV after MRM, as it significantly improves perioperative patient satisfaction and outcome. IMPLICATIONS: We evaluated the antiemetic efficacy, safety, and routine use of prophylactic ondansetron, a "gold standard" antiemetic, in women undergoing radical breast surgery who were at a high risk of postoperative vomiting. We analyzed more meaningful "true" and "therapeutic" outcome measures, and we conclude that prophylactic ondansetron is safe and effective and that its routine use is justified.

Adult↗
PubMed1981

Sexual identity and prophylactic mastectomy.

The psychological adjustment of women following prophylactic mastectomy with reconstruction has not been evaluated. This study reviews this problem in 9 women chosen at random from the practice of two surgeons. The sexual identity of the women and its effect upon the outcome of their surgery was of particular interest. The surgeon's perception of problems of adjustment and the difference in the patient's and surgeon's evaluation of operative results were considered. The study included interviews with a psychiatrist, a questionnaire for the surgeon, and a subjective evaluation of operative results by both patient and surgeon. A high degree of psychopathology, particularly depression, was encountered. Most women had a relatively weak sexual identity preoperatively. In most instances the surgeon was not alerted to the patient's troubled feelings. Though psychopathology was evident, it does not seem to indicate that the patient will have difficulty accepting the results of surgery. We suggest that women who deny their sexuality might adjust to this surgery more easily. Psychiatric consultation appears to aid patient management.

Breast Neoplasms↗
PubMed1982

Nipple-areola reconstruction after mastectomy.

Hypopigmentation, fibrosis, and the risk of autotransplantation of malignant cells have resulted in diminished enthusiasm for preserving the nipple-areolar complex after mastectomy. Adequate color match for areola reconstruction can be obtained with a full-thickness medial groin graft after breast mound symmetry has been achieved. Both a single-stage and a two-stage technique are described for nipple reconstruction. These techniques use existing approaches with some modification, and provide nipple-areolar complexes that are symmetrical, have satisfactory color match, and provide good nipple projection. Most important, the contralateral nipple-areolar complex is not violated. It can be dealt with as deemed best in terms of cancer prophylaxis.

Breast↗
PubMed1983

The use of autologous blood in patients undergoing subcutaneous mastectomy or reduction mammaplasty.

Adverse reactions are reported following 2% of transfusions. Posttransfusion viral hepatitis may occur in 8% of patients receiving homologous blood. Plastic surgery procedures, such as reduction mammaplasty and subcutaneous mastectomy, are associated with moderate blood loss that may require transfusion. Over a five-year period we offered autologous blood transfusions to 88 patients scheduled for such surgery. Approximately ten days before their operation, 72 patients each donated 450 ml of blood, which was then available for transfusion during surgery. When admitted for surgery, the patients' mean reduction in hemoglobin was 6.9%. Their average calculated blood loss was 930 ml, with a net loss of 483 ml after receiving their own blood. No complications occurred. Only 2 of these patients required an additional unit of homologous blood. Six of the 16 patients who did not donate blood preoperatively required homologous blood transfusions. The use of safe autologous blood was enthusiastically accepted by the surgical and anesthesia staff, blood bank personnel, and the patients.

Blood Transfusion, Autologous↗
PubMed1983

Subcutaneous mastectomy: current state of the art.

Subcutaneous mastectomy, although widely performed, is still considered by some to be controversial. Appropriate indications for the procedure and alternatives, as well as points of technique, complications, and secondary surgery are presented. The incidence of cancer to date in a large number of patients has been extremely low (less than 0.5%). It is the opinion of the author that under the appropriate circumstances the procedure is a good one, offering the promise in most instances of a satisfactory to excellent result.

Adult↗
PubMed1985

Pressure ulcer of the breast after subcutaneous mastectomy and reconstruction with prosthesis.

A 28-year-old woman underwent bilateral subcutaneous mastectomy and immediate reconstruction with silicone gel-filled prostheses. Three months after surgery, she developed an acute pressure sore on one side, owing to prolonged pressure of the insensitive breast against a hard surface. This complication is presented, the literature on the subject is reviewed, and brief considerations and recommendations are made.

Adult↗
PubMed1987

Thermography after subcutaneous mastectomy and reconstruction with silicone gel prosthesis: a pilot study.

Patients with subcutaneously placed silicone gel prostheses, for reconstruction after subcutaneous mastectomies, often complain of cold breasts as well as of slow regaining of warmth after cooling. We have used thermography in 7 such women and in 7 healthy women of the same age group as controls. Thermography has also been used in 3 women after repositioning of the subcutaneously placed prostheses to a submuscular position in order to study any possible changes in temperature. In 2 cases thermography also was found to aid in the diagnosis of a suspected subcutaneous displacement of a submuscular prosthesis; the technique has an advantage over mammographic examination, since thermography is a simple, less expensive, and safer method.

Bioprosthesis↗
PubMed1990

Nipple centralization for the correction of breast deformity from segmental mastectomy.

A breast deformed by lateral tissue deficiency and severe lateral displacement of the nipple, caused by the treatment of an early breast cancer with segmental mastectomy and radiotherapy, was corrected by a modification of techniques used commonly for mastopexy. The nipple and areola were moved medially on a central pedicle to create the illusion that the missing lateral tissues had been restored. Simultaneously, the opposite breast was reduced to improve symmetry. The result was a normalization of breast appearance without the need for distant tissue. It is possible that modifications of this approach could be used to treat similar deformities in other quadrants of the breast as well.

Adult↗
PubMed1999

Skin-sparing mastectomy with Sun flap closure.

Skin-sparing mastectomy lends itself to immediate reconstruction with autologous tissue, allowing a one-stage reconstruction (a nipple-areolar complex is made at the time of the initial surgery). It has been difficult to obtain equally pleasing results when immediate reconstruction with a skin-sparing technique is performed with expanders. The authors describe a modification of previously described techniques that enhance the aesthetic result of expander/implant reconstruction. This modification is called the sun flap closure.

Humans↗
PubMed2001

Results of immediate breast reconstruction after skin-sparing mastectomy.

Skin sparing mastectomy (SSM) removes the breast, nipple-areolar complex, previous biopsy incisions, and skin overlying superficial tumors. Preservation of the native skin envelope facilitates immediate breast reconstruction. The procedure has been adopted for the treatment of breast cancer. All cases of SSM and immediate breast reconstruction performed by the senior author (G.W.C.) from January 1, 1993, through December 12, 1997, were reviewed. Patient demographics, cancer staging, treatment, types of surgery performed, and postoperative outcomes were examined. Aesthetic outcomes were measured using four 3-point subscales. A total of 100 patients underwent 118 SSMs during the study period. The American Joint Committee on Cancer staging was as follows: stage 0, 27 patients; stage I, 25 patients; stage II, 39 patients; stage III, 7 patients; stage IV, 3 patients; recurrent, 2 patients; and cystosarcoma phylloides, 1 patient. The mean follow-up was 42.7 months. Local recurrence occurred in 2 patients (2.7%). Reconstructive methods included the transverse rectus abdominis musculocutaneous flap (N = 82; pedicled, 73; free, 9), the latissimus flap (N = 18), and tissue expansion (N = 20). Two patients underwent contralateral delayed reconstruction. The aesthetic results achievable with the three methods were similar. The failure rate was higher for expander reconstruction (10%) than those observed for transverse rectus abdominis musculocutaneous (4.9%) and latissimus (5.6%) flaps. SSM can be used in the treatment of invasive breast cancer without compromising local control. The aesthetic results of the three methods were similar, but tissue expander reconstruction had a higher failure rate.

Adult↗
PubMed2001

Reconstruction with the latissimus dorsi flap after skin-sparing mastectomy.

The latissimus dorsi musculocutaneous island flap was once the standard for breast reconstruction. With the increased use of tissue expanders and the development of the transverse rectus abdominis musculocutaneous flap for autologous tissue breast reconstruction, use of the latissimus dorsi has decreased. To reassess the role of the latissimus dorsi musculocutaneous flap in breast reconstruction, a retrospective review was performed to evaluate women who had skin-sparing mastectomy followed by immediate reconstruction with a latissimus dorsi flap and permanent implants. The postoperative aesthetic results and donor site morbidity, including contour deformity and scarring, were examined. Satisfactory results were obtained in 17 of 18 patients. Complications were noted in 5 patients, and all were minor. Using the latissimus dorsi musculocutaneous flap and a permanent breast prosthesis for immediate reconstruction is successful because it provides sufficient muscular coverage of the implant. In addition, it provides a good aesthetic result using a single-stage procedure. Illustrative cases are presented.

Adult↗
PubMed1981

Modified radical mastectomy with immediate reconstruction for carcinoma of the breast.

Fifty patients undergoing immediate reconstruction of the breast following modified radical mastectomy for carcinoma were characterized by their clinical findings and the pathologic features of their tumors. Evidence of nipple--areolar involvement by tumor was noted in five patients. This high incidence mitigates against nipple--areolar transplantation. In ten patients the breast contained multifocal tumor or intraductal carcinoma away from the primary tumor, thus emphasizing the importance of careful evaluation of the total tissue specimens. Four patients have had recurrence of tumor. The detection of the recurrence was not hindered by the presence of the prosthesis. In these four patients immediate reconstruction of the breast did not appear to adversely affect the natural history of the breast cancer. We suggest that when appropriate and thorough surgical extirpation followed by reconstruction is undertaken as a team effort among the general and plastic surgeons, pathologist and clinical psychologist, the optimal clinical and cosmetic results may be achieved. However, conclusive statements regarding the long-term implications of immediate reconstruction awaits additional follow-up.

Adult↗
PubMed1981

Total mastectomy with complete axillary dissection.

A technique for total mastectomy with complete axillary dissection, which uses division of the insertion of the sternal portion of the pectoralis major muscle, preservation of its innervation, reconstruction after completion of the dissection and resection of the pectoralis minor muscle has been evaluated for 115 consecutive procedures. This modification facilitates a thorough axillary dissection, while preserving the cosmetic and functional benefits of the Patey operation.

Adult↗
PubMed1984

A personal experience with Halsted's radical mastectomy.

This is a summary of Haagensen's experience with radical mastectomy over a 51-year period at the Columbia Presbyterian Medical Center. His prospective, experimental study includes 1036 patients with a follow-up of 47 years. These data are unequalled for any single method of treatment for breast carcinoma.

Breast Neoplasms↗