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Referrals by traditional birth attendants in northeast Brazil.

Between October 1980 and July 1981, 1,878 women were attended by traditional birth attendants (TBAs) at four obstetric units in rural areas surrounding the city of Fortaleza in Northeast Brazil. Of these women, 232 (12.4 per cent) were referred to a hospital in Fortaleza for delivery. The most important indicators for referral to hospital were: presence of an antenatal problem, complication of labor, or malpresentation. Based on record review, 65 referred women with none of these conditions were classified as low risk and 42 women not referred were classified as high risk (at least one such condition present). Of 1,878 deliveries, 32 (17 per 1,000) terminated as fetal deaths, and 12 infants died before discharge from hospital or obstetric unit (six per 1,000). The death rate was much higher for the high-risk cases (156 per 1,000 referrals, 95 for nonreferrals). Although some women may have been inappropriately referred while others who should have been were not referred, the system of referral has allowed TBAs to attend uncomplicated deliveries and to refer women with complications.

Adolescent↗

Outcomes of care in birth centers. The National Birth Center Study.

We studied 11,814 women admitted for labor and delivery to 84 free-standing birth centers in the United States and followed their course and that of their infants through delivery or transfer to a hospital and for at least four weeks thereafter. The women were at lower-than-average risk of a poor outcome of pregnancy, according to many but not all of the recognized demographic and behavioral risk factors. Among the women, 70.7 percent had only minor complications or none; 7.9 percent had serious emergency complications during labor and delivery or soon thereafter, such as thick meconium or severe shoulder dystocia. One woman in six (15.8 percent) was transferred to a hospital; 2.4 percent had emergency transfers. Twenty-nine percent of nulliparous women and only 7 percent of parous women were transferred, but the frequency of emergency transfers was the same. The rate of cesarean section was 4.4 percent. There were no maternal deaths. The overall intrapartum and neonatal mortality rate was 1.3 per 1000 births. The rates of infant mortality and low Apgar scores were similar to those reported in large studies of low-risk hospital births. We conclude that birth centers offer a safe and acceptable alternative to hospital confinement for selected pregnant women, particularly those who have previously had children, and that such care leads to relatively few cesarean sections.

Adolescent↗

Twin and singleton births in Ghana--a case-control study.

A retrospective study involving 623 twin and 1246 singleton births was conducted to compare the two groups with regard to selected maternal, fetal and labor and delivery characteristics and outcomes. Maternal age and parity were significantly higher for twins. The risks of preterm delivery, arrival in the labor ward in second stage of labor, cesarean births and postpartum haemorrhage were significantly higher in twin than in singleton births. In vaginal deliveries twin mothers were significantly less likely to have had episiotomies or perineal lacerations. There was no difference in the duration of the third stage of labor or in the incidence of retained placentae. Antepartum haemorrhage was a less likely indication for cesarean delivery among twins, while there was no significant difference in the likelihood of severe pre-eclampsia/eclampsia being an indication. Singleton babies were significantly heavier than twins. The incidences of malpresentation, low birth weight, stillbirths and of admission of live births to the neonatal intensive care unit were significantly higher in twins. There was no difference in the rate of instrumental vaginal delivery, or in the route of delivery of fetuses presenting by the breech. There is the need for detailed study of the incidences of antepartum haemorrhage and hypertensive diseases in twin and singleton pregnancies and of the factors determining the mode of delivery when such complications arise. Labor and delivery should also be examined to determine any differences between the two groups, especially in the first and second stages.

Adult↗

Vaginal delivery in a woman with limb-girdle muscular dystrophy. A case report.

BACKGROUND: Limb-girdle muscular dystrophy is a muscular disease determined genetically. Few papers have been published on this disorder in pregnancy. Several authors reported on delivery by cesarean section because of the risk of dystocia. CASE: A woman with limb-girdle muscular dystrophy had two pregnancies with normal vaginal delivery and follow-up. No obstetric complications related to the disease occurred. CONCLUSION: A trial of labor is possible in patients with limb-girdle muscular dystrophy if no obstetric contraindications exist.

Adult↗

Purtscher's-like retinopathy after childbirth.

Severe bilateral visual loss attributable to multiple retinal arteriolar occlusions occurred in four young women within 24 hours after childbirth. In two patients, labor was complicated by preeclampsia requiring cesarean section. One patient was suffering from pancreatitis. None had connective tissue disease or antecedent trauma. Ophthalmoscopy and fluorescein angiography revealed evidence of multiple superficial peripapillary and macular patches of ischemic retinal whitening simulating Purtscher's retinopathy. By 8 weeks, the white patches were resolving in all eyes and visual acuity had significantly improved in three of the four patients. The pathogenesis of this disorder is unknown but may involve arteriolar obstruction by complement-induced leukoemboli formed during parturition.

Adolescent↗

[Analysis of premature twin pregnancies and deliveries].

Preterm labor is the most frequent complication of twin gestation. Between 1988-1998, 123 twin pregnancies complicated by preterm labor were observed. Complications during pregnancy, mode of delivery, neonatal outcomes, mortality and morbidity were presented. We compared our outcomes to data from current literature.

Adult↗

Trends in cesarean birth and vaginal birth after previous cesarean, 1991-99.

OBJECTIVES: This report presents trends in rates of cesarean delivery and rates of vaginal birth after previous cesarean (VBAC) delivery for 1991-99. Data for the United States showing trends by maternal age, race/ethnicity, and State are presented. Also trends in cesarean rates by selected maternal characteristics, medical risk factors, and complications of labor and/or delivery are shown. A brief explanation of the Healthy People 2010 objective regarding cesarean and VBAC rates for low-risk women is also included. Summary statistics for 2000 based on preliminary data are also included, but most tabular and text information is based on detailed final statistics for 1999. METHODS: Cesarean and VBAC rates were computed based on the information reported on birth certificates. RESULTS: The U.S. cesarean rate dropped 8 percent between 1991 and 1996 (from 22.6 to 20.7 per 100 births) but then increased 6 percent between 1996 and 1999 (to 22.0); preliminary data show that the rate increased again by 4 percent between 1999 and 2000 (to 22.9). The decline between 1991 and 1996 was present for women of all ages but was most pronounced for those under 30 years of age. The decline was greatest for non-Hispanic white women, 10 percent, compared with a 7-percent decline for Hispanic women and only a 1-percent decline for non-Hispanic black women. All groups experienced increases in cesarean rates of about 6 to 7 percent between 1996 and 1999. The increase in cesarean rates between 1996 and 1999 was greatest for women 30 years of age and over. The VBAC rate increased 33 percent between 1991 and 1996 (from 21.3 to 28.3 per 100 births to women with a previous cesarean) but then fell 17 percent between 1996 and 1999 (to 23.4). The dramatic increase in VBAC rates between 1991 and 1996, followed by the subsequent decline, was experienced by women of all ages and for each major race/ethnicity group. Similar trends in cesarean rates were present for nearly all States and for most medical risk factors and complications of labor and/or delivery.

Adult↗

Amnioinfusion survey: prevalence, protocols, and complications.

OBJECTIVE: To determine whether amnioinfusion is associated with labor and delivery complications, and whether complication type and reported incidence are related to infusion method. METHODS: Questionnaires regarding amnioinfusion experience were sent to every academic obstetrics and gynecology department in the United States (78 maternal-fetal medicine fellowship directors or, if the department did not have a fellowship, 206 residency directors). A literature review on amnioinfusion was also performed. RESULTS: Seventy-six percent of fellowship directors and 62% of residency directors responded to our survey, representing 644,910 deliveries per year and at least 22,833 amnionfusions per year. A wide variety of infusion protocols were reported. Forty-nine centers reported at least one associated complication; none was significantly associated with any of the various aspects of the many protocols (P > .05). The mean number (+/- standard error of the mean) of amnioinfusions performed annually was similar between centers that did (261 +/- 48) and did not (154 +/- 29) report complications (P = .06). The literature review suggested that amnioinfusion is efficacious and relatively safe. CONCLUSION: Amnioinfusion is performed nationwide according to widely varying protocols with few associated complications. Neither the method employed nor the number of infusions performed appears to significantly increase the risk of having a complication.

Amnion↗

Precordial Doppler diagnosis of haemodynamically compromising air embolism during caesarean section.

This is a report of a 39-year-old parturient who had a haemodynamically compromising venous air embolism during a repeat Caesarean section under lumbar epidural anaesthesia. The embolism occurred immediately after surgical incision during surgery in the superficial subcutaneous tissues. The diagnosis was made using intraoperative precordial ultrasonic Doppler monitoring which allowed early and successful treatment.

Adult↗

Correction of intraoperative coagulopathy in a patient with neurofibromatosis type I with intravenous desmopressin (DDAVP).

A patient with the genetic condition neurofibromatosis type I and no known coagulopathy undergoing cesarean delivery, had diffuse uterine and surgical site bleeding that was not correctable by oxytocin, methylergonovine and PGF2 alpha. Despite good uterine tone, hemorrhage continued from the uterus and the surrounding tissues, persisting even after surgical ligation of the uterine arteries. With no change in her condition, which was behaving clinically as a coagulopathy, an infusion of desmopressin acetate (DDAVP) was begun. The patient's bleeding promptly resolved shortly after infusion of this agent. A review of relevant literature suggests that platelet reactivity of patients with neurofibromatosis type 1 is attenuated in some in vitro conditions. Thus, there may be some theoretical basis for using DDAVP in patients with neurofibromatosis type 1 who have bleeding problems with no other known source, such as in the case presented here.

Adult↗

Chronic maternal methanol inhalation in nonhuman primates (Macaca fascicularis): reproductive performance and birth outcome.

The present study was designed to characterize maternal reproductive performance and early offspring effects following exposure to methanol (MeOH) vapor in a nonhuman primate model. The two-cohort study design used 48 adult female Macaca fascicularis (24/cohort) monkeys exposed to 0, 200, 600, or 1800 ppm MeOH vapor for approximately 2.5 h/day, 7 days/week prior to breeding and throughout pregnancy. Maternal body weight measurement, clinical observations and health assessments were conducted routinely throughout the study. Menstrual cyclicity was monitored during the pre-breeding and breeding periods and timed matings were conducted with nonexposed males. Females were monitored closely during the last month of pregnancy. At birth, infant physical characteristics were measured and a newborn health assessment was conducted. Methanol exposure did not alter menstrual cycles, the number of breedings to conception or conception rate. A total of 34 live-born infants were delivered (control=8, 200 ppm=9, 600 ppm=8, 1800 ppm=9). One female each in the control and 600-ppm group delivered a stillborn infant and a cesarean section (C-section) was required to deliver a hydrocephalic infant who died in utero in the maternal 1800-ppm group. Although not statistically significant, five MeOH-exposed females were C-sectioned due to pregnancy complications such as uterine bleeding and prolonged unproductive labor. These complications were not observed in the control group. The mean length of pregnancy in the MeOH-exposed groups was significantly decreased by 6 to 8 days when compared to controls. There were no MeOH-related effects on offspring birthweight or newborn health status. The consistent reduction in length of pregnancy observed in the MeOH females may reflect a treatment effect on the fetal neuroendocrine system. Given that the fetal hypothalamic--pituitary-adrenal axis controls pregnancy length in most species, these results suggest a modest but significant effect of MeOH on the biochemical events that control the timing of birth.

Administration, Inhalation↗

Obstetric complications and rheumatic disease.

This article summarizes common fetal and maternal complications of pregnancy and emphasizes special problems in women who have systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, dermatomyositis, polymyositis, and Sjögren's syndrome. Joint management of pregnancies in these women requires an understanding of the obstetric management of the complications. Pathophysiology and treatment options for preterm-labor, preterm premature rupture of membranes, abnormal fetal growth, and hypertensive disorders of pregnancy are reviewed.

Female↗