Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Compulsive Personality Disorder”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,243 records · Page 69Linked to original sources
PubMedDate not supplied

[Pharmacotherapy in personality disorders: methodological issues and results].

The pharmacotherapy of personality disorders is less developed than are psychological treatments in this area, but they are a logical prolongation of psychobiological models of personality and temperament, and respond to the need of many clinicians in front of difficult patients. The assessment of drugs effects in personality disorders includes some important conceptual and methodological issues. Categorical or dimensional instruments evaluating baseline personality and under-treatment changes are now available. Such studies are necessary of long duration, with difficult patients, and use specific outcome criteria. The results obtained in the field of pharmacotherapy of personality disorders can be classified according to DSM IV axis-II categorization. In anxious personalities (cluster C), some isolated studies suggest a favourable effect of antidepressants on obsessive-compulsive dimension, on avoidant personality disorder, and on inhibition and trait-anxiety, especially when serotoninergic agents are used. Few studies have been conducted in cluster A personality disorders, and some are in favour of the interest of low doses of antipsychotic drugs in this group. Most studies have been conducted in cluster B, and especially in antisocial and borderline personality disorders. Partial positive results have been obtained using various classes of drugs for dealing with aggression and impulsive behaviors, including lithium, beta-blockers, carbamazepine, valproate, antipsychotic drugs, and also SSRIs. Self-harm and suicidal behaviors seem to be partially but significantly improved by antidepressants and low doses of antipsychotics. Opioid antagonisms may be helpful for these indications in the future. Other symptom-oriented strategies for psychopharmacology have been conceptualized, focused on depressive personality, emotional lability, cognitive and perceptual disturbances, or interpersonal sensitivity. Overall, the pharmacotherapy of personality disorder remains to date one of the less explored in psychiatry research. Nevertheless, it may lead in the future to the development of effective treatments, in complement to psychotherapy, for actually severe, chronic, and disabling disorder.

Antidepressive Agents↗
PubMed2004

Positive schizotypal symptoms predict treatment outcome in obsessive-compulsive disorder.

Previous research has suggested that the presence of schizotypal personality disorder may represent a risk factor for treatment failure in obsessive-compulsive disorder (OCD). Relying on a dimensional approach, the present study investigated whether the predictive importance of schizotypal personality is shared by all of its features to the same extent or whether it is confined to a subset of symptoms. Fifty-three patients underwent multi-modal cognitive-behavioral therapy with or without adjunctive antidepressive medication. Therapy response was defined as a 35% decline of the Y-BOCS total score. At baseline assessment, patients were asked to fill out the schizotypal personality questionnaire, the perceptual aberration scale and the Beck depression inventory. Stepwise regression analysis and group comparisons conducted with the schizotypal and depression scales revealed that elevated scores in the positive schizotypal scales, especially perceptual aberrations, were highly predictive for treatment failure. Responders to treatment and non-responders did not significantly differ on other variables or on scores in two scales which measured response biases. The study provides evidence that positive schizotypal symptoms are antecendents for treatment failure in OCD. It needs to be evaluated whether these at-risk individuals benefit from additional intervention, such as the adminstration of low-dose atypical neuroleptics and specifically tailored behavorial intervention.

Adult↗
PubMed2001

Autistic traits in obsessive-compulsive disorder.

In contrast to other non-psychotic psychiatric populations, subjects with obsessive-compulsive disorder (OCD) are more prone to have personality disorder from cluster A (the odd and eccentric cluster). The present study aims at further investigating the relationship between these and other personality traits in OCD subjects and their relation to high functioning autism (HFA) and Asperger disorder. Sixty-four subjects with OCD were included. Personality traits were assessed with the Karolinska Scales of Personality (KSP), and personality disorders with DSM-adapted questionnaires. In addition, autistic traits were assessed in 29 videotaped subjects, by 3 independent raters. Twenty percent of the subjects with OCD were identified as also having autistic traits. These subjects scored higher on KSP scales measuring muscular tension, psychasthenia, and inhibition of aggression and lower on socialization as compared with OCD subjects without autistic traits. Additionally, subjects with autistic traits fulfilled criteria for anxious personality disorders and paranoid personality disorders significantly more often than subjects without autistic traits. We propose that OCD is often related to HFA and Asperger disorder. Self-report questionnaires may be useful in establishing the diagnosis. However, those with the most obvious autistic features seem to be less able to identify these traits in themselves.

Adolescent↗
PubMed2003

Psychiatric comorbidity in anorexia and bulimia nervosa: nature, prevalence, and causal relationships.

Eating disorders are complex, multifactorially determined phenomena. When individuals with eating disorders present for treatment with comorbid conditions, case conceptualization is further complicated and, as a result, it may be difficult to determine optimal psychological or pharmacological treatment. This article reviews the evidence of the association between eating disorders (anorexia nervosa [AN] and bulimia nervosa [BN]) and Axis I depression, obsessive-compulsive disorder (OCD), substance abuse, and Axis II personality disorders, for the purposes of increasing awareness about the different options for case conceptualization. Although other diagnoses comorbid with eating disorders are of interest to clinicians (e.g., posttraumatic stress disorder [PTSD] and social phobia), their comprehensive review is currently premature due to a lack of empirical scrutiny. Finally, future directions for research, including suggestions for the use of particular assessment tools and more sophisticated research designs, are discussed.

Anorexia↗
PubMed1992

Compulsive personality traits affecting aeronautical adaptability in a naval aviator: a case report.

This is a case report of a male naval aviator who demonstrated compulsive personality traits which adversely affected the performance of his duties as a pilot trainee, and later, as a naval flight officer. The Diagnostic and Statistical Manual of the American Psychiatric Association (DSM-III-R) uses the term obsessive-compulsive to describe two conditions. A review of terminology is undertaken to present the reader with the distinguishing features of the personality disorder versus the anxiety disorder. The anxiety disorder, obsessive-compulsive disorder, is incompatible with safe performance of aviation duties. Obsessive-compulsive personality, on the other hand, describes a point on a continuum where useful, adaptive compulsive traits may become abnormally exaggerated and maladaptive, thus interfering with the aviator's normal routine, occupational functioning, relationships with others, and aviation safety.

Adaptation, Psychological↗
PubMed1998

Dimensions of perfectionism across the anxiety disorders.

To explore the role of perfectionism across anxiety disorders, 175 patients with either panic disorder (PD), obsessive compulsive disorder (OCD), social phobia, or specific phobia, as well as 49 nonclinical volunteers, completed two measures [Frost, R. O., Marten, P., Lahart, C., & Rosenblate, R., (1990). The dimensions of perfectionism. Cognitive Therapy and Research, 14, 449-468; Hewitt, P. L., & Flett, G. L., (1991). Perfectionism in the self and social contexts: Conceptualization, assessment and association with psychopathology. Journal of Personality and Social Psychology, 60, 456-470.] that assess a total of nine different dimensions of perfectionism. Relative to the other groups, social phobia was associated with greater concern about mistakes (CM), doubts about actions (DA), and parental criticism (PC) on one measure and more socially prescribed perfectionism (SP) on the other measure. OCD was associated with elevated DA scores relative to the other groups. PD was associated with moderate elevations on the CM and DA subscales. The remaining dimensions of perfectionism failed to differentiate among groups. The clinical implications of these findings are discussed.

Adult↗
PubMed1998

Reported sexual abuse and subsequent psychopathology among women attending psychology clinics: the mediating role of dissociation.

OBJECTIVE: While there is now a good clinical research base that outlines the links between reported sexual abuse and psychological symptoms and disorders, there is less of an understanding of the psychological processes mediating that relationship. This study assessed the role of dissociation as a mediator between reported sexual abuse and a range of psychopathological characteristics. DESIGN: A patient-series design was used. METHOD: Participants were an unselected sample of 45 women attending clinical psychology services. Each woman was interviewed regarding a reported history of sexual abuse, and completed standardized measures of general psychopathology, borderline personality disorder characteristics and dissociation. RESULTS: Sexual abuse per se was associated with the extent of depression, somatization, compulsive behaviour, phobic symptoms and borderline personality disorder characteristics. In each case, dissociation served as a complete mediator in that link. However, the same mediating relationship was not found when attempting to explain the greater psychopathological impact of more 'severe' forms of abuse (childhood experiences; intra-familial abuse). CONCLUSION: These findings suggest that the effective of clinical work with these psychopathological features would be enhanced if dissociation symptoms were addressed in women with a reported history of sexual abuse. However, the importance of that therapeutic target may be unrelated to the severity of the psychological disturbance.

Adult↗
PubMed1993

Effect of personality disorders on the treatment outcome of axis I conditions: an update.

The authors review recent studies that assess the impact of personality pathology on the treatment outcomes of axis I disorders. Studies reported include both structured treatment trials and surveys of the outcome of naturalistic treatment. Personality diagnosis in each of the studies reviewed was established by a structured diagnostic instrument. In some of the studies examined, personality traits, not categorical personality diagnoses, are reported in relation to treatment outcome. The authors describe 17 studies published within the past 3 years, and discuss them in relation to a previous review that covered 21 earlier studies. Consistent with previous investigations, recent studies continue to describe an adverse impact of personality pathology on the treatment outcome of a wide range of axis I disorders. The authors examine new studies that describe the effect of specific aspects of personality dysfunction on outcome measures of axis I disorders. New developments in this area include the predictive importance of both personality traits and disorders as well as possible specificity of traits in predicting outcome in some circumstances.

Antipsychotic Agents↗
PubMed1990

Basic character inventory personality traits among patients with major depression, anxiety disorders and mixed conditions.

Two hundred and seventy-two mainly nonpsychotic psychiatric outpatients between 19 and 59 years of age were divided into various clinical groups according to DSM-III: pure major depression, major depression in combination with various anxiety disorders, pure anxiety disorders and a group with other mental disorders. The groups were compared as to differences in personality traits assessed by means of the Basic Character Inventory. The mixed major depression/non-panic anxiety disorder group appeared to be the most deviant with more oral-neurotic personality traits in addition to obsessive traits, while the pure major depressive disorder and the pure anxiety disorder group were less disturbed. Especially cases with non-panic-anxiety features in addition to major depression were those which manifested a neurotic obsessive personality structure. These findings imply that it is important to distinguish between major depression cases with and without various anxiety disorders.

Adult↗
PubMedDate not supplied

Emergence and the cognitive neuroscience approach to psychiatry.

In this paper, I introduce the philosophical notion of strong emergence and argue that it is almost exclusively applied to properties related to (conscious) subjective experience. Contrary to the still common attitude of refraining anxiously from these topics, I argue that we have a promising scientific approach to them: the cognitive neurosciences. I list a spectrum of interesting, potentially strongly emergent properties already investigated, and discuss the example of volition in more detail. Psychiatric disorders, like antisocial personality disorder, schizophrenia, and obsessive compulsive disorder, open new ways for understanding aspects of volition such as willed action, decision making, and agency. I conclude that the notion of strong emergence is only a preliminary label which, however, might be understood as a challenge for empirical scientists to explain and understand phenomena related to subjectivity and consciousness.

Antisocial Personality Disorder↗
PubMed1991

Neuropsychiatric aspects of stroke.

Neuropsychiatric disorders following stroke are common, and pathologic involvement of specific regions or functional systems results in behavioral syndromes similar to idiopathic psychiatric syndromes. Depression occurs in up to half of all stroke patients and is most frequently associated with left anterior cortical and subcortical infarctions. Mood changes interfere with cognitive, functional and social recovery. Treatment with heterocyclic antidepressants, stimulants, and electroconvulsive therapy is efficacious in most patients. Mania, delusions, hallucinations, personality alterations, obsessive-compulsive disorder, and changes in sexual behavior are less common but have also been described in post-stroke patients. Each behavioral syndrome is associated with a specific pattern of brain involvement. Investigation of these phenomena contributes to understanding the cerebral basis of psychiatric disorders.

Brain Damage, Chronic↗
PubMed2000

Prevalence of personality disorders among combat veterans with posttraumatic stress disorder.

Many combat veterans with PTSD have co-occurring symptoms of other forms of psychopathology; however, there have been limited studies examining personality disorders among this population. The few extant studies typically have assessed only two or three personality disorders or examined a small sample, resulting in an incomplete picture and scope of comorbidity. This study assessed all DSM-III-R personality disorders in 107 veterans in a specialized, inpatient unit. Using the Structured Clinical Interview for DSM-III-R Personality Disorders, 79.4% of the participants were diagnosed with at least one personality disorder: 29.9% received only one diagnosis, 21.5% had two, 15.9% had three, and 12.1% had four or more. The most frequent single diagnoses were Avoidant (47.2%), Paranoid (46.2%), Obsessive-Compulsive (28.3%), and Antisocial (15.1%) personality disorders.

Cluster Analysis↗
PubMed2004

Orthorexia nervosa: a preliminary study with a proposal for diagnosis and an attempt to measure the dimension of the phenomenon.

AIM: To propose a diagnostic proceeding and to try to verify the prevalence of orthorexia nervosa (ON), an eating disorder defined as "a maniacal obsession for healthy foods". MATERIALS AND METHODS: 404 subjects were enrolled. Diagnosis of ON was based on both the presence of a disorder with obsessive-compulsive personality features and an exaggerated healthy eating behaviour pattern. RESULTS: Of the 404 subjects examined, 28 were found to suffer from ON (prevalence of 6.9%). The analysis of the physiological characteristics, the social-cultural and the psychological behaviour that characterises subjects suffering from ON shows a higher prevalence in men and in those with a lower level of education. The orthorexic subjects attribute characteristics that show their specific "feelings" towards food ("dangerous" to describe a conserved product, "artificial" for industrially produced products, "healthy" for biological produce) and demonstrate a strong or uncontrollable desire to eat when feeling nervous, excited, happy or guilty.

Adult↗
PubMed2002

[Frontotemporal dementia].

Frontotemporal dementia is a rare form of progressive intellectual deterioration. Its most prominent clinical features are alterations in personality, motivation, and social conduct whereas memory and orientation remain largely unimpaired. Several underlying neurodegenerative processes may be distinguished which are confined to the cerebral cortex in most cases but occasionally involve the basal ganglia and rarely the anterior horn cells. Most frequently, histopathological examination reveals a non-specific loss of neurons accompanied by reactive gliosis. In a minority of cases, globose intraneuronal inclusions and achromatic ballooned neurons are seen. These peculiar morphological changes are called "Pick bodies" and "Pick cells" after the neurologist Arnold Pick who worked in Prague. It can be difficult to identify frontotemporal dementia because its major symptoms mimicnon-organic psychiatric disorders including mania, obsessive-compulsive disorder, schizophrenia, depression or personality disorder. Another problem of diagnosis is that all clinical instruments that are available for assessing cognition, activities of daily living, and non-cognitive symptoms have been tailored to the prototypic dementia in Alzheimer's disease and are less sensitive to the psychopathology of frontal lobe diseases. The burden that frontotemporal dementia imposes on caregivers is also completely different from the one encountered by families of patients with the more prevalent dementias. In the present contribution we summarize the current evidence on epidemiology, aetiology, and risk factors of frontotemporal dementia. Clinical symptoms and course will be illustrated by a case example. We will also provide guidelines for diagnosis and discuss treatment options.

Aged↗
PubMed1990

Reversible and irreversible monoamine oxidase inhibitors in other psychiatric disorders.

In addition to being effective in depressive disorders, monoamine oxidase inhibitors (MAOIs) have been shown to be effective in controlled studies of patient with panic disorder with agoraphobia, social phobia, atypical depression or mixed anxiety and depression, bulimia, posttraumatic stress disorder (PTSD) and borderline personality disorder. Uncontrolled case reports have noted MAOI efficacy in obsessive-compulsive disorder (OCD), trichotillomania, dysmorphophobia and avoidant personality disorder. Reversible inhibitors of MAO-A (RIMAs) appear safer than the classical irreversible MAOIs since they have less potential to increase blood pressure. They have not been studied as yet, however, in most of the conditions responsive to MAOIs. If RIMAs are found effective in these disorders, they would probably achieve wider use than MAOIs because they are safer and tend to cause fewer side effects.

Antidepressive Agents↗