Consumer behavior analysis for improved dental services marketing.
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Choice Behavior↗
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Assessment of functional impairment following permanent middle cerebral artery occlusion in a non-human primate species.
The purpose of the present study was to examine and quantify the functional consequence of a focal cerebral ischaemic lesion in a primate species, the marmoset. Following craniotomy and retraction of the frontal and temporal lobes, the middle cerebral artery was permanently occluded by means of electrocoagulation. Three and eight weeks after surgery, various behavioural tests were used to give a quantifiable measure to the neurological deficits produced. These tests required the monkeys to reach into tubes for foodbits, retrieve rewards from the steps of two designs of 'staircases', respond to one of two simultaneously presented rewarded tubes, remove adhesive labels attached to their feet, and respond to sensory stimuli. Unilateral motor impairment of the contralateral forelimb and neglect of contralateral tactile stimuli were seen in all subjects, and spatial neglect was also present in some monkeys. Subsequent histological analysis revealed unilateral cortical damage in all subjects with varying amounts of injury to the caudate and the putamen in some animals. These results demonstrate the potential for the use of this species in future investigations to examine the effect of neuroprotective treatment on functional outcome after a focal ischaemic insult.
Animals↗
Memory impairment in obese Zucker rats: an investigation of cognitive function in an animal model of insulin resistance and obesity.
The genetically obese Zucker rat is a widely investigated model of pathological changes associated with type 2 diabetes. To assess cognitive function, obese and lean Zucker rats were tested on a variable-interval delayed alternation test of learning and memory. There were no group differences in learning the alternation rule or at short intervals, but obese rats were impaired at longer intervals where performance is hippocampus dependent. Plasma membrane association of the insulin sensitive glucose transporter, GLUT4, was reduced in the hippocampus of obese rats in the absence of changes in total GLUT4 and insulin receptor expression. These results parallel those of human studies in pointing to the susceptibility of the hippocampus and related structures to the adverse environment of diabetes mellitus.
Analysis of Variance↗
Patterns of alcohol, cigarette and illicit drug use in English adolescents.
AIMS: The aim of this study was to describe associations between alcohol, tobacco and illicit drug use in adolescents and demographic factors associated with substance use. DESIGN, SETTING, SUBJECTS: The study was a classroom survey of the total population of pupils (n = 5383, ages 11-16) in six schools selected from different locations around England. MEASURES: Respondents were asked confidentially about their use and extent of use of alcohol, cigarettes and illegal drugs. FINDINGS: The prevalence of regular substance use within the sample rose from 30.4% at age 11 to 83.9% at age 16. The prevalence of alcohol use did not differ between girls and boys, but smoking was more prevalent in girls and illegal drug use was more prevalent in boys. Alcohol was used more frequently than any other substance, or combination of substances, and alcohol use almost invariably accompanied the use of other substances: exclusive use of cigarettes or illegal drugs was negligible. In addition, high levels of alcohol intoxication were associated with increased use of both illegal drugs and cigarettes. Overall, around half the drinkers (46.8%) preferred alcopops to other types of alcoholic drink; this figure was greater in girls (56.4%) than in boys (37.1%), but fell sharply with age (62.9% at age 11; 37.7% at age 16), particularly in boys. Preference for spirits increased with age, and was particularly marked in girls (28.4% in girls vs. 18.5% in boys at age 16). Spirits drinkers were more likely to use cigarettes and drugs, and had been more frequently drunk, than either beer/wine or alcopops drinkers; these measures also tended to be higher in alcopop drinkers than in beer/wine drinkers, particularly among 11-13-year-old girls. CONCLUSION: The use of both tobacco and illicit drugs appears to be strongly associated with alcohol use, which is more prevalent, and the risk of smoking and illicit drug use is particularly high in adolescents who report high levels of drunkenness. Our results are consistent with a simple threshold model of substance abuse in which alcohol occupies a low threshold position relative to the higher threshold of cigarettes and illegal drugs. Smoking, drug use and drunkenness were lowest in beer/wine drinkers, intermediate in alcopop drinkers, and highest in spirits drinkers.
Adolescent↗
Inter-ethnic differences in youth tobacco language and cigarette brand preferences.
OBJECTIVE: To describe and understand variations in cigarette brand preferences between adolescents from varying ethnic and gender groups around the US. DESIGN: A qualitative study where adolescents, both smokers and nonsmokers, were interviewed individually in depth. SETTING: Schools and recreation centers in four sites: urban Maryland (Baltimore), urban Texas (Houston), rural Alabama and rural New Mexico. PARTICIPANTS: 121 adolescent volunteers 13-19 years of age, representing African American, white, American Indian and Hispanic ethnic groups, from both genders. RESULTS: Considerable geographic and ethnic variation exists in terminology used by youth to refer to cigarettes and to their use. Clear patterns in brand preference by ethnic group were found that follow patterns of targeted marketing by ethnicity. White teens preferred Marlboro brand cigarettes, while African-American teens who smoke preferred Newports. Hispanic and American Indian teens were more likely to smoke Marlboro or Camel cigarettes. Hispanic teens were most likely to mention low price as a reason for choosing a particular brand or to state that the brand does not matter. Tobacco advertisements targeting ethnic groups and the use of promotional items to encourage teen smoking were also recognized as factors influencing brand preferences. CONCLUSIONS: These findings have implications for the design of intervention programs aimed at curbing teen smoking. When working with teens who already smoke, using youth language to target messages at perceived characteristics of commonly used brands may be more effective and meaningful than talking about cigarette use in general. Another implication of this work is to shed light on what impact an advertising ban would have on teen brand preferences, brand loyalty, and prevalence of smoking.
Adolescent↗
Neuropsychological effects of risperidone in children with pervasive developmental disorders: a blinded discontinuation study.
OBJECTIVE: Little is known about the neuropsychological effects of risperidone in children with pervasive developmental disorders. METHOD: Twenty-four children (aged 5-17 years) with pervasive developmental disorders and co-morbid disruptive behavior who responded favorably to open-label treatment with risperidone as part of a previously described controlled discontinuation study completed two different computerized attention tasks at baseline, weeks 4, 8, and 24 of open-label treatment, and, at 8 weeks after random assignment to either placebo or risperidone. The primary efficacy measures were response latencies to visually presented stimuli requiring two different types of attention-controlled processing, i.e., focused and divided attention. RESULTS: About half of the clinical responders did not produce valid performance measures. These could be shown to be of younger mental age and less adaptive as measured by the Vineland Behavior Scales. For the valid task performers divided attention (serial search in working memory) was shown to regress in the placebo group (n = 7), while in the risperidone group (n = 7) there was further improvement. No such group difference was found for focused attention. CONCLUSIONS: The study suggests a beneficial effect of risperidone after several months of treatment, enhancing divided attention in children with pervasive developmental disorders.
Adolescent↗
Role of angiotensin II and the subfornical organ in the pharmacological actions of ethanol.
AIMS: The current study was designed to evaluate if angiotensin II mediates the hypothermic effects of ethanol, and to determine if the effects of angiotensin are mediated centrally. We also tested the hypothesis that the subfornical organ (SFO) is a site responsible for the alterations in body temperature and aerial righting reflex mediated by ethanol and for the modulation of ethanol consumption in rats. METHODS: Male Sprague-Dawley rats were used in a series of experiments to evaluate the role of both peripheral and central administration of losartan, a selective angiotensin type 1 receptor antagonist on ethanol-induced hypothermia. Subsequent studies were undertaken in SFO-lesioned rats to evaluate the effects of SFO-lesion on alcohol intake, the thermal response to alcohol and angiotensin, and the aerial righting reflex. RESULTS: Selective antagonism of the angiotensin II type 1 receptor, administered either peripherally or centrally, attenuated not only the fall in colonic temperature but also attenuated the transient rise in tail skin temperature that was associated with administration of ethanol. The thermal responses to both angiotensin and ethanol were similarly attenuated in SFO-lesioned rats. Likewise the aerial righting reflex, which has previously been shown to be impaired by losartan treatment, was also significantly attenuated in SFO-lesioned animals. Alcohol intake, as determined by a 48 h, two-bottle preference test also revealed that SFO-lesioned animals consumed significantly less alcohol (ethanolic beer) than did controls. CONCLUSION: Collectively, the results demonstrate that ethanol-induced temperature responses are mediated by the renin-angiotensin system and that this interaction is mediated centrally. In addition, the results demonstrate that the SFO is a site that mediates several neurobiological effects of ethanol, possibly via the renin-angiotensin system.
Angiotensin II↗
The cAMP-protein kinase A signal transduction pathway modulates ethanol consumption and sedative effects of ethanol.
Ethanol and other drugs of abuse modulate cAMP-PKA signaling within the mesolimbic reward pathway. To understand the role of the cAMP-PKA signal transduction in mediating the effects of ethanol, we have studied ethanol consumption and the sedative effects of ethanol in three lines of genetically modified mice. We report that mice with the targeted disruption of one Gsalpha allele as well as mice with reduced neuronal PKA activity have decreased alcohol consumption compared with their wild-type littermates. Genetic reduction of cAMP-PKA signaling also makes mice more sensitive to the sedative effects of ethanol, although plasma ethanol concentrations are unaffected. In contrast, mice with increased adenylyl cyclase activity resulting from the transgenic expression of a constitutively active form of Gsalpha in neurons within the forebrain are less sensitive to the sedative effects of ethanol. Thus, the cAMP-PKA signal transduction pathway is critical in modulating sensitivity to the sedative effects of ethanol as well as influencing alcohol consumption.
Adenylyl Cyclases↗
Body build stereotypes and self-identification in three age groups of females.
Body build stereotypes of three age groups (6, 15, and 19 years old) of average weight and "heavy" female students were studied. First, the students were asked to circle one adjective from each of 28 antonym pairs, which was "most like" themselves. Concurrently, side-view figures of a female endormorph, an ectomorph, and a mesomorph were shown to each student. The figures were of the approximate age of the student. She was asked to point to one of the figures which "best fit" the adjectives in each of the 18 antonym pairs as they were read aloud. Lastly, each student was asked to choose one of the figures which "most looked" like themselves and the one which they would most want to "look like". Thus, discrepancies could be detected between one's self description and one's description of others with a very similar physique. The hypothesis that females would have similar physique preferences and aversions as those of males in a previous study (3) was confirmed. Females preferred the mesomorph figure (p less than .001) and at least favored the endomorph figure (p less than .001). The ectomorph figure was viewed less negatively than the endomorph figure (p less than .01). The youngest group showed more preference towards the endomorph and ectomorph figures then did the two older groups. "Heavy" physique students rejected the behavioral stereotypes descriptive of themselves even though they earlier had associated the very same stereotypes to the physique most like their own.
Adolescent↗
[Asymmetry of movement direction as a tactic in the feeding behavior of rats].
The sign and degree of spatial-motor asymmetry in rats were studied in conditions both of spontaneous or signalled choice in an U-maze and spontaneous multiple choice in a radial labyrinth. It was shown that during investigation of a new environment, motor asymmetry in rats was feebly expressed in all conditions of experiments, irrespective of the labyrinth scheme and experimental procedures. In the process of training, adequate behaviour was formed and in some conditions a distinctly expressed spatial asymmetry appeared, while in other cases it was absent. Apparently, while investigating an "unknown" situation (where rats can move rightwards and leftwards), the strategy of "displacement" is characteristic of them. Later the rate of asymmetry manifestation depends on concrete spatial and temporal characteristics of already "familiar" surroundings.
Animals↗
Reframing: a strategy to improve care of manipulative patients.
The use of reframing as a means of increasing nurses' choices in their behavioral responses to manipulative patients and an example of how the process might be used to influence nurses' perceptions are discussed. Perceptions influence nurses' behavioral responses. As individuals, nurses become accustomed to approaching new situations with familiar behaviors, and they lose sight of alternative responses. Choices will expand through the process of reframing, an intervention commonly utilized in therapy situations and a method for challenging the attitudes, values, and responses of a person. Simply defined, reframing is changing a person's interpretation of a given situation and therefore changing his or her behavioral response to it. Expanding nurses' choices is a step toward providing improved patient care.
Attitude of Health Personnel↗
Health behavior: issues, contradictions and dilemmas.
American medicine faces many contradictions and dilemmas. This is especially the case with regard to preventive health behavior. This paper explores the effects of several issues, contradictions and dilemmas on the American experience with primary preventive health behavior. These issues include: individualism, victim blaming, therapeutic nihilism, the over abundance of health information, America as a culture of risk takers, and the dilemma of the jungle vs the zoo. Four types of health behavior are defined. The first type of health behavior is the primary prevention of disease, defect, injury or disability. The second type is detection of asymptomatic disease, injury and defect. Third, is the promotion of enhanced levels of health, wellness and quality of life. And the fourth, at a more societal level, protective behaviors to make environmental transactions safe from disease, injury, defect and disability. These four types of health behavior are each explored in relation to societal values, technology and economics to determine which of these facilitate or impede health behavior at both the individual and societal levels.
Choice Behavior↗
Three-month-olds' visual preference for faces and its underlying visual processing mechanisms.
This study was aimed at investigating the face preference phenomenon and its underlying mechanisms at 3 months of age. Using an eye-tracker apparatus, Experiment 1 demonstrated that 3-month-olds prefer natural face images to unnatural ones, replicating and extending previous evidence obtained with schematic facelike stimuli. Experiments 2 and 3 showed that the general mechanisms that induce face preference in newborns could not explain the same phenomenon at 3 months of age, when infants are attracted by perceptual cues more specific to faces. This suggests that signs of a process of cognitive specialization are already present in 3-month-olds' visual behavior toward faces.
Choice Behavior↗
Does aggression cause a preference for viewing media violence?
Virtually all of the research concerned with media violence has attempted to determine whether the viewing of violence is associated with or causes aggression. Little experimental research has been directed at understanding why persons view media violence. The present research experimentally tested the hypotheses that physical aggression and fantasy aggression would lead to a preference for viewing violence. In Experiment 1, undergraduate men and women were induced to express aggressive, nonaggressive, or no fantasies and were then given an opportunity to select film clips for viewing. The films chosen by men contained more violence than those chosen by women. In addition, aggressive fantasies in males, compared to nonaggressive fantasies, increased the preference for viewing violence. Experiment 2, using only males, replicated the results of the first study and also found that men who were given an opportunity to aggress physically, compared to those who had no such opportunity, were more likely to choose to view films containing violent content. These results provide an additional perspective on the relationship between the observation of violence and the expression of aggression by suggesting that the causal effects are bidirectional: Just as the viewing of violence may increase aggression, so, too, aggressive behavior may increase the preference for viewing violence.
Aggression↗
The cognitive impact of past behavior: influences on beliefs, attitudes, and future behavioral decisions.
To study the processes by which past behavior influences future behavior, participants were led to believe that without being aware of it, they had expressed either support for or opposition to the institution of comprehensive exams. Judgment and response time data suggested that participants' perceptions of their past behavior often influenced their decisions to repeat the behavior. This influence was partly the result of cognitive activity that influenced participants' cognitions about specific behavioral consequences and the attitude they based on these cognitions. More generally, however, feedback about past behavior had a direct effect on participants' attitudes and ultimate behavioral decisions that was independent of the outcome-specific cognitions. Results are discussed in terms of their implications for biased scanning of memory, dissonance reduction, self-perception, and the use of behavior as a heuristic.
Adult↗
Peer influence on risk taking, risk preference, and risky decision making in adolescence and adulthood: an experimental study.
In this study, 306 individuals in 3 age groups--adolescents (13-16), youths (18-22), and adults (24 and older)--completed 2 questionnaire measures assessing risk preference and risky decision making, and 1 behavioral task measuring risk taking. Participants in each age group were randomly assigned to complete the measures either alone or with 2 same-aged peers. Analyses indicated that (a) risk taking and risky decision making decreased with age; (b) participants took more risks, focused more on the benefits than the costs of risky behavior, and made riskier decisions when in peer groups than alone; and (c) peer effects on risk taking and risky decision making were stronger among adolescents and youths than adults. These findings support the idea that adolescents are more inclined toward risky behavior and risky decision making than are adults and that peer influence plays an important role in explaining risky behavior during adolescence.
Adolescent↗
Explaining sex differences in managerial career satisfier preferences: the role of gender self-schema.
Using survey data from 400 managers, the authors examined whether gender self-schema would explain sex differences in preferences for status-based and socioemotional career satisfiers. Female gender self-schema, represented by femininity and family role salience, completely mediated the relationship between managers' sex and preferences for socioemotional career satisfiers. However, male gender self-schema, represented by masculinity and career role salience, did not mediate the relationship between managers' sex and preferences for status-based career satisfiers. As expected, male managers regarded status-based career satisfiers as more important and socioemotional career satisfiers as less important than female managers did. The proposed conceptualization of male and female gender self-schemas, which was supported by the data, enhances understanding of adult self-schema and work-related attitudes and behavior.
Career Choice↗
Dopamine antagonists do not block conditioned place preference induced by paced mating behavior in female rats.
The authors assessed the behavioral effects of dopamine (DA) receptor antagonists, Cis (Z) flupentixol and S(+)-raclopride L-tartrate, on conditioned place preference (CPP) induced by paced mating behavior. Ovariectomized female rats of the Wistar strain were used. The administration of amphetamine (1 mg/kg) induced a clear CPP that was completely blocked by the DA antagonists flupentixol (0.25 mg/kg) or raclopride (0.125 mg/kg). These doses had no effect on motor coordination. Female rats that mated in a pacing chamber developed a clear CPP. Neither flupentixol nor raclopride blocked the reward state induced by paced mating behavior. These results indicate that DA is not involved in the reward state induced by paced mating behavior in female rats.
Animals↗