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Theoretical nuclear database for high-energy, heavy-ion (HZE) transport.

Theoretical methods for estimating high-energy, heavy-ion (HZE) particle absorption and fragmentation cross-sections are described and compared with available experimental data. Differences between theory and experiment range from several percent for absorption cross-sections up to about 25%-50% for fragmentation cross-sections.

Cosmic Radiation↗

Cosmological implications of the Machian principle.

The famous idea of Ernst Mach concerning the non-absolute but relational character of particle inertia is taken up in this paper and is reinvestigated with respect to its cosmological implications. From Thirring's general relativistic study of the old Newtonian problem of the relativity of rotations in different reference systems, it appears that the equivalence principle with respect to rotating reference systems, if at all, can only be extended to the system of the whole universe, if the mass of the universe scales with the effective radius or extent of the universe. A reanalysis of Thirring's derivations still reveals this astonishing result, and thus the general question must be posed: how serious this result has to be taken with respect to cosmological implications. As we will show, the equivalence principle is, in fact, fulfilled by a universe with vanishing curvature, i.e. with a curvature parameter k = 0, which just has the critical density rho (crit) = (3H)(2)/8piG, where H is the Hubble constant. It turns out, however, that this principle can only permanently be fulfilled in an evolving cosmos, if the cosmic mass density, different from its conventional behaviour, varies with the reciprocal of the squared cosmic scale. This, in fact, would automatically be realized, if the mass of each cosmic particle scales with the scale of the universe. The latter fact, on one hand, is a field-theoretical request from a general relativistic field theory which fulfills H. Weyl's requirement of a conformal scale invariance. On the other hand, it can perhaps also be concluded on purely physical grounds, when taking into account that as source of the cosmic metrics only an effective mass density can be taken. This mass density represents the bare mass density reduced by its mass equivalent of gravitational self-binding energy. Some interesting cosmological conclusions connected with this fact are pointed out in this paper.

Astronomical Phenomena↗

The use of a syncytium model of the crystalline lens of the eye as a new tool to study the light flashes phenomenon seen by astronauts.

A syncytium model to study some electrical properties of the eye is proposed to study the phenomenon of anomalous light flashes (LF) perceived by astronauts in orbit. The crystalline lens is modelled as an ellipsoidal syncytium with a variable relative dielectric constant. The corresponding mathematical model is a boundary value problem for a system of two coupled elliptic partial differential equations in the two unknown syncytial electrical potentials. A numerical method to compute an approximate solution of this mathematical model is used, and some numerical results are shown. The model can be regarded as a new tool to study the LF phenomenon. In particular, the energy lost in the syncytium by a transversing cosmic charged particle is calculated and the results obtained with the syncytium model are compared with those obtained using the previously available Geant 3.21 simulation program. In addition, the interaction of antimatter-syncytium is studied, and the Creme96 computer program is used to evaluate the cosmic ray fluxes encountered by the International Space Station in its standard mission.

Aerospace Medicine↗

On the connection between hard cosmic ray flux variations and changes in cardiovascular disease in Vilnius city.

A predictive correlation between hard cosmic ray flux (HCRF) near the Earth's surface and sudden increases in the number of cases of cardiovascular disease (CVD) was studied in Vilnius city. Gamma spectrometers were used to measure HCRF. Changes in the total number of impulses registered by these devices were taken as the physical parameter for prediction of an increase in the number of CVD cases. For quantitative assessment of CVD dynamics two empirical criteria for HCRF were proposed: (1) a consistent fall in the HCRF by 200 or more impulses for 4 or more hours per day; (2) the difference (no less than 15 impulses per hour) between the average number of impulses registered in 2 (subsequent and previous) days. The periods analyzed were those when the number of CVD cases exceeded the average monthly level by 10% and 15%. HCRF fluctuations were used as an indirect indicator of variations in the geomagnetic field, and a leap in CVD cases was predicted 1-3 days following a change in the HCRF according to the two criteria mentioned above. The predictive reliability of an increase in CVD cases within 2-3 days exceeded 80%, and within 1-2 days 70%. No essential difference in predictive reliability was observed when the number of CVD cases exceeded the average monthly level by 10% or 15%. Geomagnetic field variations contribute only insignificantly to leaps in the number of CVD cases, which are evoked by the sum effects of other factors. The results of the present study should be regarded as preliminary.

Cardiovascular Diseases↗

Chromosome aberration and environmental physical activity: Down syndrome and solar and cosmic ray activity, Israel, 1990-2000.

The possibility that environmental effects are associated with chromosome aberrations and various congenital pathologies has been discussed previously. Recent advances in the collection and computerization of data make studying these potential associations more feasible. The aim of this study was to investigate a possible link between the number of Down syndrome (DS) cases detected prenatally or at birth yearly in Israel over a 10-year period compared with the levels of solar and cosmic ray activity 1 year before the detection or birth of each affected child. Information about 1,108,449 births was collected for the years 1990-2000, excluding 1991, when data were unavailable. A total of 1,310 cases of DS were detected prenatally or at birth--138 in the non-Jewish community and 1,172 in the Jewish population. Solar activity indices--sunspot number and solar radio flux 2,800 MHz at 10.7 cm wavelength for 1989-1999--were compared with the number of DS cases detected. Pearson correlation coefficients (r) and their probabilities (P) were established for the percentage of DS cases in the whole population. There was a significant inverse correlation between the indices of solar activity and the number of cases of DS detected--r=-0.78, P=0.008 for sunspot number and r=-0.76, P=0.01 for solar flux. The possibility that cosmophysical factors inversely related to solar activity play a role in the pathogenesis of chromosome aberrations should be considered. We have confirmed a strong trend towards an association between the cosmic ray activity level and the incidence of DS.

Chromosome Aberrations↗

Cosmogenic and nucleogenic isotopic changes in Mars: their rates and implications to the evolutionary history of Martian surface.

We present calculations of rates of production of several nuclides in the Martian atmosphere and in the regolith due to nuclear interactions of cosmic ray and radiogenic particles and consider their implications to the evolutionary history of Mars. Nuclides selected are those which, considering their chemical properties, may be useful as tracers for delineating the past histories of the Martian atmosphere and regolith. Calculations are presented for different assumed atmospheric pressures. The regolith production rates for the present thin Martian atmosphere (approximately 20 g cm-2) are expected to be fairly robust because they are based primarily on observed cosmogenic effects in the Moon, for which semiempirical estimates of nuclide production rates have been provided earlier by Reedy (1981). Uncertainties which arise in the calculations of nuclide production rates for an earlier hypothetical Martian atmosphere of approximately 300-500 g cm-2 thickness are discussed. Compared to cosmic ray production rates, the nucleogenic production rates are smaller by several orders of magnitude. However, the nucleogenic production extends to much deeper levels, whereas the cosmogenic production is essentially confined to the top 750-1000 g cm-2 depth. Important examples of nucleogenic production are discussed. Isotopes of neon and argon appear to be very promising for delineating relative magnitudes of a number of planetary processes related to the temporal changes in the thickness of the atmosphere, as well as their release from the regolith. However, quantification of the processes would require higher-precision isotopic data for the atmosphere and also direct measurements of isotopic ratios in the Martian regolith, along with supplementary information on changes in the isotopic compositions of hydrogen, carbon, and nitrogen, which are affected by a variety of mechanisms of escape of gases from the atmosphere. Cosmogenic effects are minimal in these cases. We show that although we can at present draw but limited inferences, the planet Mars presents a unique opportunity to use cosmogenic nuclides as tools to delineate the evolutionary history of the planet as a whole, as well as its regolith and the atmosphere. This arises because of two factors: minimal degassing of the planet, and a fairly intense chemical weathering history of the upper surface. Consequently, an appreciable fraction of some of the isotopes of volatile elements is contributed by nuclear reactions.

Argon↗

Hydrocarbon nucleation and aerosol formation in Neptune's atmosphere.

Photodissociation of methane at high altitude levels in Neptune's atmosphere leads to the production of complex hydrocarbon species such as acetylene (C2H2), ethane (C2H6), methylacetylene (CH3C2H), propane (C3H8), diacetylene (C4H2), and butane (C4H8). These gases diffuse to the lower stratosphere where temperatures are low enough to initiate condensation. Particle formation may not occur readily, however, as the vapor species become supersaturated. We present a theoretical analysis of particle formation mechanisms at conditions relevant to Neptune's troposphere and stratosphere and show that hydrocarbon nucleation is very inefficient under Neptunian conditions: saturation ratios much greater than unity are required for aerosol formation by either homogeneous, heterogeneous, or ion-induced nucleation. Homogeneous nucleation will not be important for any of the hydrocarbon species considered; however, both heterogeneous and ion-induced nucleation should be possible on Neptune for most of the above species. The relative effectiveness of heterogeneous and ion-induced nucleation depends on the physical and thermodynamic properties of the particular species, the abundance of the condensable species, the temperature at which the vapor becomes supersaturated, and the number and type of condensation nuclei or ions available. Typical saturation ratios required for observable particle formation rates on Neptune range from approximately 3 for heterogeneous nucleation of methane in the upper troposphere to greater than 1000 for heterogeneous nucleation of methylacetylene, diacetylene, and butane in the lower stratosphere. Thus, methane clouds may form slightly above, and stratospheric hazes far below, their saturation levels. When used in conjunction with the results of detailed models of atmospheric photochemistry, our nucleation models place realistic constraints on the altitude levels at which we expect hydrocarbon hazes or clouds to form on Neptune.

Atmosphere↗

Respective role of microgravity and cosmic rays on Paramecium tetraurelia cultured aboard Salyut 6.

Paramecium tetraurelia cultured aboard Salyut 6 have shown in increase in cell growth rate, cell volume, water content and changes in electrolyte content. Additional experiments, carried out in balloon flight and on earth, showed that the stimulating effect observed on cell proliferation is related to exposure to cosmic rays. Other changes seem to be due to a direct effect of microgravity on cell. Mechanism of gravity action on cell is discussed.

Animals↗

Assessment of Space Station design and operation through Bioastronautics.

The paper reviews the main elements and major issues affecting human productivity and discusses some selected factors which might not be sufficiently identified and/or considered from the Bioastronautics point of view at the present stage of planning Space Station design and operation.

Aerospace Medicine↗

Medical concerns for exploration-class missions.

The Space Exploration Initiative will challenge life scientists with a diverse set of crew medical risks. The varied sources of this cumulative risk are identified and briefly discussed in terms of risk assessment and preliminary plans for risk management. The roles of Space Station Freedom and other flight programs are discussed in the context of exploration medical objectives; and the significant differences between Space Station era (second generation) and exploration medical support systems (third generation) are reviewed.

Aerospace Medicine↗

Real time dose rate and LET spectrum aboard MIR station during 1992.

Since the end of July 1992, the NAUSICAA system, a low gas pressured tissue equivalent proportional counter, recorded in real time the dose equivalent rate, the absorbed dose rate, the quality factor and the Linear Energy Transfer spectra, aboard the Russian orbital station MIR. The results since the ANTARES mission are presented. Some parameters like the proton flux, the previous solar cycles, the location of the NAUSICAA system inside the station and the South Atlantic Anomaly crossing seem to have an influence on these results. The total dose equivalent (H) during the ANTARES mission (between 1992 July the 30th and August the 10th) was 12 mSv and the total absorbed dose (D) 6.4 mGy with a quality factor (Q) equal to 1.9. The NAUSICAA system gives a good knowledge of LET spectra for the first time in space dosimetry.

Atlantic Ocean↗

Effects of sublethal irradiation with helium ions (300 MeV/nucleon) on basic hematological parameters of mice.

The aim of the experiment was to obtain new knowledge on the biological effectiveness of high-energy (300 MeV/nucleon) helium ions, which represent a part of the spectrum of cosmic rays. Male (CBA x C57BL)F1 mice, 4 months old, were exposed to a dose of 4 Gy helium ions (exposure rate 0.05 Gy/min). As a comparative standard irradiation the same dose of 4 Gy of 137Cs gamma-rays (exposure rate 0.07 Gy/min) was used. Material sampling was performed 6-8 h, 4 days and 9 days after irradiation for both experimental groups mentioned above. There were 7 animals in each group including the control group of non-irradiated mice. Eight basic hematological parameters of peripheral blood, bone marrow, spleen and thymus were studied. On day 4 after the irradiation with helium ions, the values of leukocyte counts in peripheral blood, bone marrow cellularity and spleen cellularity were reduced to about 10% of the respective control values while the decline after irradiation with gamma-rays amounted to about 50%. These and other results presented reflect a high relative biological effectiveness of 300 MeV/nucleon helium ions.

Animals↗

Dosimetric measurements in manned missions.

Detector packages consisting of thermoluminescence detectors (TLDs), nuclear emulsions and plastic nuclear track detectors were exposed in different sections of the MIR space station, inside the Spacelab during the IML1 mission, and inside Spacelab module and tunnel during the D2 mission. This report concentrates on total dose measurements with TLDs during these mission. The results are discussed and compared to results of former missions and to calculations. Finally, dose equivalents and mean quality factors for each mission are presented which are derived from the TLD results and results obtained from the other detector systems. Dose equivalents range between 200 microSvd-1 and 700 microSvd-1.

Aerospace Medicine↗

Introduction.

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Adaptation, Physiological↗