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Role of intraoperative manometry in renal artery compression by a pheochromocytoma.

A case of renal artery stenosis due to compression by a neurofibrous cord (histologically a pheochromocytoma) and resolved by the débridment of the vessel and angioplasty with a patch in the saphenous vein, is reported. After the compression has been relieved, the vessel appeared normal at inspection and palpation (pulsation); the manometric control, recorded distally and proximally to the area of compression by the pheochromocytoma showed a significant gradient of pressure that led to the exploration of the vessel, partially obstructed by a recent thrombus. These lesions were not detectable solely on inspection and palpation. It is stressed that a restored normal aspect after removal of the extrinsic pressure on the renal artery may not represent an equivalent optimal restoration of function. Only manometric control or rate of flow measurements are able to assess the efficacy of surgical reconstruction.

Adrenal Gland Neoplasms↗

[Evaluation of the effect of flunitrazepam on the lower esophageal sphincter in man with intraluminal manometry].

The effect of Flunitrazepam on the human lower oesophageal sphincter is evaluated. Pressure in the LOS and GOR using the Acid Reflux Test was evaluated in 22 surgical cases at rest (after ingestions of a placebo and Flunitrazepam). The results obtained indicate that the LOS pressure variations induced by flunitrazepam significantly increase the probability of GOR.

Esophagogastric Junction↗

[Results of anorectal manometry for the determination of age- and sex-dependent pressure differences].

Manometric findings in 88 anorectal healthy probands are reported. Basal (PAC) and maximal squeeze (PAC max) pressures in the anal canal as well as rectal pressure at rest (PAR) and the pressure increase in the anal canal after dilatation of the ampulla recti (delta PAC) were registered with a 2 balloon catheter and statistically analysed in the 52 male and 36 female probands, divided in three age groups (group I under 40 years, group II 40-60 years and group III over 60 years). PAC showed for all three groups a statistically significant difference for men and women as well as a statistically significant decrease with age in both sex groups. PAC max, PAR and PAC decreased statistically significantly with age in both sex groups whereas in the three age groups, men and women showed nearly equal values. These age- and sex correlated differences in the anorectal pressure profile must be considered in the evaluation of the continence function.

Adolescent↗

Manometry with needle cholangiography. A new technique.

A new method of cholangiomanometry developed on the basis of operative needle cholangiography is described. The pressure of the common bile duct is recorded during continuous infusion using two different speeds. The procedure is complemented by pressure controlled injections of a contrast medium and by fentanyl test to study the function of the sphincter of Oddi.

Cholangiography↗

[Significance of manometry in the functional diagnosis of anal continence].

Using small size catheters with perfusion of 2 ml water/min. quantitative and reproductive measurements are possible without irritation of the anal canal. With our technique of measurement we could characterize the anal function both for physiological and pathological conditions of continence. The influences of sphincter saving operations on the anal continence in the rectal surgery were analysed.

Anal Canal↗

A clinical trial with pre- and post-treatment manometry comparing pneumatic dilation with bouginage for treatment of Chagas' megaesophagus.

The physiologic similarities between the megaesophagus of Chagas' disease and idiopathic achalasia are well documented. Therefore, it would seem reasonable that comparisons of controlled trials of therapy for the more common Chagas' megaesophagus could be applied to idiopathic achalasia, where the paucity of cases makes such a controlled comparison difficult. We had the opportunity to study 18 patients with achalasia secondary to Chagas' disease. All of the patients were from the mid central states of Brazil, all had symptoms of dysphagia and radiographic documentation of dilated esophagus and abnormal peristalsis (Rezende Groups II and III), as well as positive serologic evidence of Chagas' disease. Perfused intraluminal manometric studies were performed on all patients. Resting sphincter pressures ranged from 20-35 mm./Hg., mean of 25 (normal 5-12 mm./Hg.) with aperistalsis. Patients were randomly dilated with either bouginage (44-55 ff catheter) or pneumatic dilator (4-4.5 kg./6.5 cm.2 x 2 min.). Although all patients reported symptomatic improvement several days after either procedure, repeat manometric tracings demonstrated no change in the sphincter pressure in the bouginage group. The pneumatically dilated group, however, demonstrated a decrease in sphincter pressure to normal levels (mean 12 mm./Hg.). Follow-up studies one year after the procedure confirmed the persistence of normal sphincter pressure in the pneumatically dilated group but no change, as well as return of initial symptoms, in the bouginage group.

Adult↗

A new simplified technique for pediatric anorectal manometry.

Using a new simple technique that is well tolerated and rapid for assessing anal sphincter functions in pediatric patients with fecal incontinence and constipation, 86 patients with varying degrees of anorectal dysfunction were tested. A microtip pressure transducer was used for recording anal sphincter responses to rectal balloon distension. Results were obtained within 15 to 30 minutes. In 17 patients, the internal anal sphincter showed no response or positive spike to balloon distension, consistent with the manometric diagnosis of aganglionic megacolon. These findings were confirmed by absence of ganglion cells on rectal biopsy. Sixty-nine children had normal internal sphincter relaxation to rectal distension. Ganglion cells were present in nine biopsy specimens. In the remaining 60 patients, no further workup of aganglionosis was necessary. There were no false-positive or false-negative results. This technique has proved to be effective for initial evaluation of infants and children with constipation and encopresis.

Adolescent↗