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The identification of temporomandibular joint disease through the masticatory cycle.

The purpose of this study was to determine, by analyzing the masticatory cycle, the presence of TMJ disease prior to initiating any orthodontic treatment. Masticatory data from 80 pre-orthodontic patients were recorded in the frontal and sagittal planes and then analyzed and compared with the pre-established healthy masticatory data of Maruyama et al. 40% of the sample group presented with signs and/or symptoms of masticatory dysfunction and/or temporomandibular joint abnormalities (TMJA). Using Student's t test we found significant differences in the means for all seven parameters measured. Patients with TMJA exhibited significantly slower closing, occlusal and total cycle times, but faster opening. It was usually possible to determine which joint was compromised by the disease from the data.

Female↗

Nutraceutical therapies for degenerative joint diseases: a critical review.

There is growing recognition of the importance of nutritional factors in the maintenance of bone and joint health, and that nutritional imbalance combined with endocrine abnormalities may be involved in the pathogenesis of osteoarthritis (OA) and osteochondritis dissecans (OCD). Despite this, dietary programs have played a secondary role in the management of these connective tissue disorders. Articular cartilage is critically dependent upon the regular provision of nutrients (glucose and amino acids), vitamins (particularly vitamin C), and essential trace elements (zinc, magnesium, and copper). Therefore, dietary supplementation programs and nutraceuticals used in conjunction with non-steroidal, anti-inflammatory drugs (NSAIDs) may offer significant benefits to patients with joint disorders, such as OA and OCD. This article examines the available clinical evidence for the efficacy of nutraceuticals, antioxidant vitamin C, polyphenols, essential fatty acids, and mineral cofactors in the treatment of OA and related joint disorders in humans and veterinary species. This article also attempts to clarify the current state of knowledge. It also highlights the need for additional targeted research to elucidate the changes in nutritional status and potential alterations to the expression of plasma membrane transport systems in synovial structures in pathophysiological states, so that current therapy and future treatments may be better focused.

Amino Acids↗

Therapies for peripheral joint disease in psoriatic arthritis. A systematic review.

Traditional drug treatments for psoriatic arthritis (PsA) include nonsteroidal antiinflammatory agents (NSAID) and disease modifying antirheumatic drugs (DMARD), although the evidence base for their effectiveness is not well established. This review was compiled from a comprehensive literature search of electronic bibliographic databases for all English publications that were systematic reviews, metaanalyses, randomized controlled trials, controlled trials, and observational studies. The evidence supports NSAID for symptom relief, although data are lacking for COX-2-specific agents. No evidence exists to support systemic corticosteroids or corticosteroids by intraarticular injection, although the latter are commonly used in clinical practice. Among traditional DMARD, grade 1B evidence supports sulfasalazine, cyclosporine, and leflunomide for symptom relief, with lower-grade evidence for methotrexate. None of them slows radiographic progression. Grade 1B evidence supports improvement in symptoms, physical function, quality of life, and radiographic progression with anti-TNF antagonists (etanercept, infliximab, and adalimumab). The relative lack of evidence poses challenges in developing algorithms for treatment of peripheral arthritis in PsA.

Anti-Inflammatory Agents, Non-Steroidal↗

[Thermography in the complex examination of patients with temporomandibular joint diseases].

The authors describe the usage of thermovisual investigation for diagnostic and treatment control purposes in patients with the temporomandibular joint pathology. In chronic arthritis exacerbations, traumatic arthritis and arthroses the joint thermographic images are different. Thermometry was performed at distinct points of parotidmusticulatory, submandibular and cervical regions. Normal and pathological thermal gradients were found between symmetrical facial sites.

Adolescent↗

Preliminary study of joint disease in poultry by the analysis of synovial fluid.

Samples of synovial fluid and synovial membrane were obtained from the hock joints of several groups of broilers, including lame birds and two strains of broilers raised on different feeding regimens and given different drug treatments (carprofen or placebo). There were more significant differences between the groups on the basis of the analysis of the synovial fluid samples than the synovial membrane samples. Experimental birds fed ad libitum had the highest median red blood cell counts and median ghost cell counts of all of the groups, but there were no differences between the groups in the thickness of the synovial lining cell layer or the degree of cellular infiltrate in the synovial membrane. The synovial fluid from the broilers and lame birds fed ad libitum was more turbid, suggestive of intra-articular pathology, and the large numbers of heterophils in samples from the lame birds indicated an inflammatory arthropathy. The birds fed ad libitum which were treated with carprofen had more cells in the synovial fluid than the birds given the placebo. A large number of the samples of synovial fluid from the ad libitum-fed broilers contained blood.

Animal Husbandry↗

Bone and joint diseases around the world. Arthritis--the greatest health, disability, and civil rights challenge: a UK and international perspective.

The Bone and Joint Decade provides the opportunity for arthritis to be put firmly on political agendas worldwide. Greater political priority is crucial for everybody with arthritis, no matter where they live. People are "patients" for part of their lives, and people all the time, bringing to attention the need to address issues such as social exclusion, access to services, and negative attitudes and practices in society. The term "disability" is not synonymous with "inability," and should be embraced by people with arthritis. As a concept the term can be empowering to individuals, bonding those who face similar problems, including social exclusion and discrimination. When it is stripped of negative connotations, disability can also offer a positive identity. In the UK, the Disability Discrimination Act 1995 was the product of 25 years of campaigning by people who strongly believed that such discrimination should be illegal. The Act is not perfect and important parts have still to be implemented, but it exists as a resource for people with arthritis who may face discrimination. Only a minority of nations have disability discrimination legislation. Law alone will not end discrimination. If people with arthritis do not identify with being disabled then many people who meet the legal definition will continue to face unnecessary discrimination daily. A moral responsibility exists to help make the term one that attracts rather than deters those whom we seek to represent.

Arthritis↗

Destructive joint disease following replantation of digits of the hand.

Microsurgical techniques now often allow the repair of severed digits. After noticing destructive joint changes in a patient who underwent such repair, the authors examined the postoperative radiographs of 27 other patients who underwent repair of severed digits at the University Hospital, London, Ontario, between 1984 and 1987. They found five patients who were similarly affected. The mechanism of destruction is not known, but the authors believe that osteonecrosis plays a role or that the cause may be neurovascular.

Adolescent↗

Degenerative temporomandibular joint disease: surgical treatment and long-term results.

PURPOSE: In this study, the long-term evaluation after surgical treatment of temporomandibular joint with manifested degenerative changes and internal derangement is described. The surgical procedure, including extensive exploration and remodeling of the joint, with interposition of lyophilized human costochondral cartilage, is described. MATERIALS AND METHODS: Thirty-two cases (37 joints) were evaluated at a mean follow-up time of 3.1 and 8.6 years after the surgical treatment. RESULTS: A significant reduction of dysfunction and pain symptoms was achieved in most cases.

Adolescent↗