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At least 1,225 records · Page 68Linked to original sources
PubMed1998

Capillaries with fenestrations around regenerating muscle fibers in the soleus muscle of the dystrophic (dy) mouse.

To investigate the morphological changes in capillaries around regenerating muscle fibers in the dystrophic (dy) mouse, we examined capillaries in the soleus muscles of 30-day-old control and dy mice by electron microscopy. In the control mice, the intramuscular capillaries were continuous. In the dystrophic mice, the muscles contained degenerative muscle fibers and many small muscle fibers regenerating after necrosis; these fibers had centrally located nuclei. The capillaries in the dy mice were mostly continuous, but some had a narrow vascular lumen around regenerating muscle fibers, possibly indicating newly formed capillaries. Moreover, about 20% of the capillaries with a narrow vascular lumen had a small number (less than five) of fenestrae bridged by a single-layered diaphragm. These findings suggest that capillary networks around muscle fibers regenerating after necrosis are remodeled by newly formed capillaries, and some of these capillaries have fenestrae in the endothelium to increase the supply of nutrients and oxygen to the regenerating muscle fibers.

Animals↗
PubMed1996

Aortopulmonary fenestration with pulmonary artery septation for single ventricle and subaortic obstruction.

A neonate with functional single ventricle and severe subaortic obstruction received a palliative procedure that involved a side-to-side anastomosis of the aorta and pulmonary artery, placement of a patch in the main pulmonary artery to divide the systemic and pulmonary circulations, and creation of a small opening in the patch to provide pulmonary blood flow. The patient recently underwent a bidirectional Glenn procedure at 10 months of age. This procedure obviates the need for a modified Blalock-Taussig shunt and may provide a more reliable source of blood to promote growth of both pulmonary arteries.

Anastomosis, Surgical↗
PubMed1983

The use of ligament efficiency to model fenestrations in the internal elastic lamina of cerebral arteries. II--analysis of the spatial geometry.

During uniaxial extension of the latex model, the holes (both marked on the sheet and perforated) demonstrated a distinctive change in their shape, from circular to elliptical. Measurements of the axial and transverse diameters of a consistent row of holes, along with the width of the sample at distinct elongations were converted into an area, ligament efficiency (transverse and axial) and shape factor (eccentricity). Values for the expansion ratio of the holes and necking of the latex sheet were also computed. The perforations expanded more rapidly than with the holes only marked on the solid material, which translated into a more rapid increase for the axial diameter, area and eccentricity, while the axial ligament efficiency decreased more rapidly. The transverse diameter and transverse ligament efficiency remained essentially constant. Necking of the latex sheet was consistent for all of the specimens (both solid and perforated). The relative expansion ratios paralleled the relative changes for the standardized stresses presented in Part I.

Biomechanical Phenomena↗