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At least 1,225 records · Page 68Linked to original sources
PubMed1977

A computer program for calculating different kinds of intraclass correlation coefficients.

A program for calculating different forms of intraclass correlation coefficients is described. Confidence limits as well as unbiased estimates are given for those kinds of coefficients, for which an exact sampling distribution is derivable. Additionally, coefficients based upon Krippendorff's model are computed so that error components responsible for the lack of perfect correlation can be specified.

Computers↗
PubMed1994

[The use of a computer program to study gallbladder motor function].

Gallbladder motility was studied in 30 women by means of an ultrasonographic method. Gallbladder volume was examined during intravenous infusion of ceruletide (15 ng Takus/min in 0.9% NaCl solution). It was several dozen less than the dose given intramuscularly. The volume and ejection fraction were defined by the ellipsoid Dodds method in the computer programme Cardio 500. During the infusion of ceruletide it was possible to identify exactly the dose of the drug in every moment and to correlate it with the gallbladder volume. Contour's analysis in Simpson's method made possible to evaluate the contractility of individual parts of the gallbladder.

Adult↗
PubMed1977

Semiautomatic processing of neurophysiological data: part II--a computer program for data reduction.

This paper describes a program for the processing of trains of nerve or muscle impulses (spikes). The program is designed to allow the efficient use of semiautomatic or manual measuring devices. It will handle up to six different sets of spikes and one cyclic,non-spike event (e.g., changing light intensity or limb position, etc.) Output may include computed interspike intervals and instantaneous frequencies, phase relationships between sets of spikes and between spikes and the non-spike event, and parameters of bursts found in the spike trains. Output is presented numerically and in the form of line-printer graphs,

Action Potentials↗
PubMed1986

A computer program package for restriction map analysis and manipulation.

Programs for the calculation, storage and analysis of restriction maps derived from the analysis of partial digestion products from end labelled DNA (1,2,3) and their correlation with digestion - and hybridisation patterns in total digestions and Southern blot experiments are described. These programs allow direct input of gel patterns from partial or complete digestion experiments using a digitizer tablet, calculation of molecular weights and restriction maps, plotting of maps and actual or predicted fragment patterns and automated identification of overlapping cosmids from partial restriction mapping results. Programs are written in PASCAL and have been implemented on a VAX/VMS system, with a HP-7221T plotter and a digitizing tablet.

Cloning, Molecular↗
PubMed1980

A package of computer programs designed to simulate pharmacokinetic monitoring of drug therapy.

Three programs are presented which have been developed to simulate conditions encountered in the pharmacokinetic adjustment of dosage regimens. The programs include a drug with one-compartment kinetics, whose elimination is dependent on renal function (gentamicin), a drug with two-compartment kinetics (theophylline), and a drug whose elimination follows non-linear Michaelis-Menten kinetics (phenytoin). The programs may be used as an aid to instruction in clinical pharmacokinetics and to develop and test new methods of pharmacokinetic adjustment of dosage regimens.

Computers↗
PubMed1978

BANDSCAN--a computer program for on-line linear scanning of human banded chromosomes.

BANDSCAN, an interactive program for on-line linear scanning of human G-banded chromosomes quantitative analysis is described. This program was written for a Wang 720 C programmable desk calculator associated to the Zeiss scanning photometer MP01. The system can detect up to a maximum of 24 densitometric band peaks found along banded chromosome arms or chromatids, estimate the total arm length and localize bands in terms of their relative positions. The scanning stage under control is always returned to the pre-fixed scanning starting point (centromere) which allows a user to scan the specimen repeatedly at different sensitivities and thus to reject minor bands or suspected chromosome artifacts. This facilitates a better visualization of major bands and chromosome landmarks. A fully formated print-out on band localizations and their relative positions is obtained at the end of each scanning. The possibilities of the application of this program to band mapping of human chromosomes and to the study of small chromosome band aberrations is discussed.

Animals↗
PubMed1980

Automated processing of dynamic properties of intraventricular pressure by computer program and electronic circuit.

A procedure for automatic detection and digital processing of the maximum first derivative of the intraventricular pressure (dp/dtmax), time to dp/dtmax(t - dp/dt) and beat-to-beat intervals have been developed. The procedure integrates simple electronic circuits with a short program using a simple algorithm for the detection of the points of interest. The tasks of differentiating the pressure signal and detecting the onset of contraction were done by electronics, while the tasks of finding the values of dp/dtmax, t - dp/dt, beat-to-beat intervals and all computations needed were done by software. Software/hardware 'trade off' considerations and the accuracy and reliability of the system are discussed.

Analog-Digital Conversion↗
PubMed2006

Computer program for automated sleep depth estimation.

In this article, we present a new implementation of an amplitude-independent method for continuous-scale sleep depth estimation. Having been implemented as an add-on analysis module under commercially available biosignal recording and analysis software, it can be easily applied in clinical routine. The software gives the user full freedom to change all the analysis parameters inside theoretical limits. Computational sleep depth profiles produced by the presented software compare favourably with visual classifications. Future work will concentrate on systematic optimization of analysis parameters, further evaluation of the method with disturbed sleep and application of the method for automated adaptive sleep analysis.

Electronic Data Processing↗
PubMed1979

A computer program for topographic analysis of biomolecular systems.

This program essentially generates a picture of a space filling molecular model. By precise simulation of the intersections between atoms, leaving out the 'hidden line', a good perspective is produced. Additional three dimensional information is provided by simulating reflection spots on the surface. This program has been used to visualise three dimensional surface features of biologically important molecules (e.g., valinomycin). With slight modification the program can be used to visualise enzyme active sites and receptor surfaces. It can also be used to create animated motion pictures of molecular dynamics.

Chemical Phenomena↗
PubMed1976

Description of a computer program for the determination of regional cerebral blood flow.

The regional cerebral blood flow in man was measured, following a short injection 133 Xenon into the internal carotid, by processing the hemispheric clearance curves detected with an Anger gamma-camera. An automatic calculation program is described which permits the estimation of the two compartmental blood flows. The merits of this procedure are discussed.

Cerebrovascular Circulation↗
PubMedDate not supplied

Development of interactive patient-based multimedia computer programs in veterinary orthopedic radiology.

Three computerized multimedia programs on large and small animal veterinary orthopedic radiology were developed and implemented for the radiology curriculum as an alternative to traditional film-based laboratory learning. Programs utilized "hot words" (colored text words that displayed an overlaid image label that highlighted lesions) and interactive quizzes which responded appropriately to selected answers. "Hot words" helped students develop confidence in accurate lesion detection and the interactive quizzes transformed learning from a passive to an active process. Multiple examples were provided for reinforcement and concepts were incorporated from other clinical disciplines for curriculum integration. Programs were written using a presentation software program, Toolbook for DOS based platform, and contained radiographic images made by laser-scanning digitization. Multiple students could simultaneously access the programs through a network server. These pilot programs were implemented successfully and computerized multimedia presentation proved to be well suited to teaching radiology. Development of the programs required attention to a number of hardware, software, time and cost factors.

Computer Communication Networks↗