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At least 1,225 records · Page 68Linked to original sources
PubMed2006

[Vesicourethral anastomotic stricture after radical prostatectomy secondary to migration of a metal clip].

The frequency of vesicourethral anastomotic stricture after prostatectomy is estimated to be 14%, an average of 3 months after the operation. The authors report the cases of a 61-year-old man undergoing radical prostatectomy for localized prostate cancer. The postoperative course was marked by recurrent urinary retention and several urethrotomies failed to restore spontaneous voiding. A clip was finally visualized and removed by endoscopy. The patient has not experienced any further episodes of retention. This is the first published cases of clip migration responsible for anastomotic stricture after radical prostatectomy. This diagnosis must be considered in the case of repeated postoperative retention.

Anastomosis, Surgical↗
PubMed1991

Tubuloglomerular feedback in one-kidney, one-clip hypertensive rats.

Previous studies have shown that hydropenic one-kidney, one-clip (1-K, 1-C) hypertensive HT rats exhibit impaired autoregulation of glomerular filtration rate (GFR) in response to reduced arterial perfusion pressure. We investigated the possible role of altered tubuloglomerular feedback (TGF) activity in this phenomenon. Uninephrectomized Wistar rats were studied acutely 3 weeks after placing silver clips (0.2 mm) on the renal artery. Experiments were performed in 1-K,1-C HT rats and in uninephrectomized control animals. TGF activity was assessed as changes in proximal tubule stop-flow pressure (SFP) in response to orthograde microperfusion from 0 to 80 nl/min into late proximal tubule segments. Only the highest perfusion rates (approximately 40 nl/min) into late proximal tubule segments resulted in maximal decreases in SFP, indicating a marked rightward shift of overall TGF activity in 1-K,1-C HT rats. Similar responses were observed in the uninephrectomized animals. In contrast, changes of SFP were observed at lower perfusion rates in normal animals and maximal responses were observed at perfusion rates of approximately 20 nl/min. These observations are consistent with the possibility that altered TGF activity contributes to impaired autoregulation of GFR in 1-K,1-C HT rats in response to reduced renal perfusion pressure. In response to treatment with i.v. captopril, the 1-K,1-C HT rats exhibited marked decreases in systemic arterial pressure associated with decreases in SFP and virtually complete inhibition of TGF activity. It is attractive to hypothesize that these alterations in TGF characteristics in the 1-K,1-C HT rats play a significant pathophysiologic role in the acute renal dysfunction observed in response to acute decreases of blood pressure during conditions of augmented angiotensin activity. Additional future studies will allow us to address the precise role for intrarenal angiotensin in these phenomena.

Angiotensin II↗
PubMed1991

The effect of prostaglandin E1 on local cerebral blood flow during cerebral-aneurysm clip ligation.

Prostaglandin E1(PGE1) was administered for deliberate hypotension during general anaesthesia in 27 patients undergoing cerebral-aneurysm clip ligation, and the effect of the drug on local cerebral blood flow was studied. Local cerebral blood flow measurements were made using a thermal-gradient blood flowmeter. Control measurements were made immediately before administration of the drug. Local cerebral blood flow was measured 10, 30, 60 and 120 min after starting the drug infusion and 10, 30 and 60 min after discontinuation. The mean blood pressure was reduced significantly by the administration of PGE1. Urine output was increased after commencement of the drug infusion. Local cerebral blood flow did not change. These results suggest that PGE1 may be an appropriate hypotensive drug for use during cerebral-aneurysm clip ligation, because the cerebral blood flow remains within the normal range and the urine output is increased.

Alprostadil↗
PubMed1990

Baroreceptor resetting facilitates the onset of one-kidney, one clip hypertension.

1. A previous study from our laboratory demonstrated the occurrence of transient tachycardia during the onset of one-kidney, one clip (1K1C) hypertension in conscious rats. In the present study, using electroneurographic recordings in anesthetized rats, we investigated the time course of baroreceptor resetting at the onset (3, 7, 14 and 21 days) of 1K1C hypertension. 2. There was no significant difference between the diastolic pressure of hypertensive animals and the systolic threshold pressure for baroreceptor activation in normotensive control rats (100 +/- 3 vs 92 +/- 5 mmHg), and hypertensive rats 3 (118 +/- 3 vs 112 +/- 5 mmHg), 7 (125 +/- 6 vs 119 +/- 5 mmHg), 14 (135 +/- 11 vs 125 +/- 10 mmHg) and 21 (154 +/- 6 vs 150 +/- 8 mmHg) days after clipping. 3. These data indicate that the baroreceptors were completely reset to the hypertensive levels during the periods studied and also suggest that baroreceptor resetting may play a facilitatory role for the onset of tachycardia and the development of 1K1C hypertension in the conscious animal model.

Analysis of Variance↗
PubMedDate not supplied

Small aneurysm clips for surgery of neck vessels.

Surgery of the internal carotid artery and the extracranial vertebral artery is of a fundamentally preventive nature, and justifiable when intra and postoperative complications (intraoperative stroke, postoperative vessel occlusion, postoperative TIA and/or stroke) remain within very low limits (less than 5% according to major case-series'). To minimize damage to the arterial wall that could cause vessel occlusion and even neurological damage, the authors propose the use of intracranial aneurysm clips for temporary closure of the neck vessels, explaining the methods used for selection of these clips.

Aneurysm↗
PubMed1989

Suprapontine ablation in normal and Doc-salt or one-kidney, one-clip hypertensive rats.

The role of suprapontine areas in the acute maintenance of the hypertension in awake Doc-salt (4 weeks of treatment) or one-kidney, one clip (1K-1C) (4 weeks after clipping) rats was studied. Mean blood pressure (BP) and heart rate (HR) were measured before (15 min) and after (2 hours) removing all brain tissues rostral to the pons. After this procedure no change in BP was found in normal or 1K-1C rats. In Doc-salt rats the BP falls (154 +/- 4 to 110 +/- 5 mmHg; p less than 0.001). HR was increased in normal (351 +/- 10 to 446 +/- 20 beats/min; p less than 0.01) and in 1K-1C rats (350 +/- 10 to 485 +/- 12 beats/min; p less than 0.001). Clonidine injected into the cisterna magna in 1K-1C rats after suprapontine ablation lowered BP (146 +/- 6 to 118 +/- 11 mmHg; p less than 0.05) and HR (515 +/- 17 to 400 +/- 33; p less than 0.05). Pentolinium reduced BP after the suprapontine ablation in normal (116 +/- 4 to 63 +/- 5 mmHg; p less than 0.001), Doc-salt (111 +/- 5 to 53 +/- 3; p less than 0.001) and 1K-1C rats (163 +/- 8 to 59 +/- 6 mmHg; p less than 0.001). These data suggest that suprapontine structures have an important role in the acute maintenance of Doc-salt hypertension. In 1K-1C rats the acute maintenance of hypertension depends on a sympathetic activity originated below the lesion.

Animals↗
PubMedDate not supplied

[The saphenous clip].

The purpose of the saphenous clip is to prevent two major factors in the course of varicose vein disease: the haemodynamic factor and the parietal factor, the latter being the cause of post-surgical recurrences. Positioning of the clip is only imaginable after thorough mapping of the sapheno-femoral junction by Doppler and ultrasonography. They offer a precise and selective surgical indication, preserving healthy vessels. The first results confirm its efficacy on these two essential factors. However, the reflux is not always controlled while recurrences are not always occurring after 4 years.

Adult↗
PubMed1986

Effect of antihypertensive treatment on the left ventricular isomyosin profile in one-clip, two kidney hypertensive rats.

In order to investigate the cardiac effects of antihypertensive therapies in one-clip two-kidney hypertension in rats, we compared the consequences on myosin isoenzyme profile and on left ventricular hypertrophy of two treatments: one was a new converting enzyme inhibitor (S9490), the second a more standard tripletherapy associating clonidine, dihydralazine and furosemide. The two treatments were initiated 4 weeks after clipping and administered during 5 weeks. During the treatment period average systolic blood pressure was 215 +/- 32 mmHg in the hypertensive untreated group (HC2, n = 12) and 144 +/- 13 mm Hg in the CEI group (HT1, n = 13), which is not significantly different from the value found in the sham-operated group (139 +/- 4 mm Hg, C2, n = 13). Blood pressure was lowered only to 173 +/- 18 mm Hg in the group treated with tripletherapy (HT2, n = 12). The left ventricular weight decreased significantly in the CEI-treated group toward values similar to those of the sham-operated animals (2.2 +/- 0.13 mg/g vs. 1.9 +/- 10 mg/g, respectively NS), whereas it did not change in the tripletherapy group when compared to the untreated hypertensive animals despite the fall in blood pressure. In the hypertensive untreated rats the percentage of V1 isoenzyme of cardiac myosin was lower than in the sham-operated group (42.8 +/- 9.0% vs. 57.5 +/- 7.6% P less than .001). In parallel the V3 form of cardiac myosin increased (24.1 +/- 7.4% vs. 15.7 +/- 4.3%, P less than .001).(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1988

Adrenal and vascular renin-like activity in chronic 'two-kidney, one-clip' hypertensive rats.

In order to study the vascular and adrenal renin angiotensin system in the chronic phase (4 months after clipping) of 'two-kidney, one-clip' hypertension in rats, systolic blood pressure, plasma renin activity, and tissue renin-like activity in both aorta and adrenal have been measured. Renin activity in adrenal gland was studied in both the zona glomerulosa (GLO) and the remainder of the gland. Results showed an increase in vascular renin activity in chronic hypertensive rats. Moreover it was found that GLO of hypertensive rats presented a significant increase in renin-like activity compared with controls (349.43 +/- 43.86 versus 167 +/- 34.25 ng AI/g/20 h, p less than 0.01) and the fasciculata-reticular-medullar (FRM) portion also showed greater renin activity (345.16 +/- 64.36 versus 57.90 +/- 4.83 ng AI/g/20 h, p less than 0.01). The higher levels of vascular and FRM renin-like activity in chronic renal hypertension are probably a consequence of plasma renin increase. This hypothesis is supported by the fact that bilateral nephrectomy in normal rats induces a significant decrease in plasma renin activity and both aortic and FRM renin-like activity. On the other hand the GLO renin-like activity could depend on both plasma renin and local synthesis since bilateral nephrectomy induces an increase in the renin-like activity in this tissue. These data support the idea that aortic and FRM renin are, at least in part, due to plasma renin uptake and GLO renin is an autonomic system.

Adrenal Glands↗
PubMed1988

[Cardiovascular effects of peptide inhibitors of the renin-substrate reaction in rats with renovascular hypertension. Goldblatt: 2 kidneys--1 clip].

The antihypertensive effects of 2 different peptidic substrate analogs: AG 84-10 AG 85-12 were investigated in renovascular hypertensive (Goldblatt, 2 kidneys--1 clip) Sprague-Dawley male rats. AG 84-10 (Ac-Pro-Phe-His-Leu-Val-Tyr) is similar to Angiotensinogen 6-13 and AG 85-12 (Ac-Ile-His-Pro-Phe-His-Leu) mimics the C-terminal portion of Angiotensin I. 6 weeks after clipping, hemodynamic profiles of these molecules [Heart rate (HR), mean arterial pressure (MAP), filling parameters, peripheral vascular resistances (PR) and cardiac output (CO)] during 90 minutes, were determined in the anesthetized animals. CO was measured using a thermodilution technique. Parallel radio-immunologic dosages of plasma renin activity were performed. Measurements and calculation of previously defined hemodynamic variables, every 10 minutes, demonstrated that: AG 84-10 exerted an early but transient decrease of MAP and PR, an increase of CO without modification of other hemodynamic parameters. AG 85-12 induced a late and durable decrease of MAP and PR with a significant decrease of heart rate, but without modification of CO and other hemodynamic variables. Example: PR mmHg/ml/mn/kg (mean +/- SD): *p less than 0.05 ** p less than 0.01. (Table: see text). The different levels of plasma renin activity were in accordance with hemodynamic data. So, the 2 peptidic substrate analogs elicited antihypertensive effects with a more efficient action of AG 85-12.

Animals↗
PubMed1979

[Low esophageal stenosis and pyloric obstruction: 2 complications of a Prioton clip].

The authors report a case of digestive hemorrhage due to rupture of oesophageal varices, for which treatment by means of a Prioton oesophageal clip was effective but followed by two rare complications: pyloric stenosis by migration of the balloon of the gastrostomy catheter and retention of the clip which required its removal by oesophagotomy. Analysis of the mechanism of these complications rarely encountered in the literature suggests a method of prevention.

Esophageal Stenosis↗
PubMed1988

Operative cholangiography using a modified disposable vascular clip.

After frequent use of this modified disposable clip, obtaining cholangiograms has been both easy and quick while minimizing trauma to the tissues of the cystic duct. The clip can be used safely through any incision, small or large, and it is a good tool in facilitating the interoperative cholangiogram.

Catheterization↗
PubMed1986

Peripheral haemodynamics after surgical reversal of two-kidney, one clip renal hypertension in rats.

The changes in peripheral haemodynamics and regional resistances were studied during the rapid fall in mean arterial pressure (MAP) after surgical reversal of two-kidney, one clip renal hypertension in rats (RHR). The controls used were sham-declipped RHR and normotensive control rats (NCR). During the 2 h following renal artery declipping or sham-operation, MAP and heart rate (HR) were followed continuously. Finally, the regional blood flows in the kidneys, small intestine and skeletal muscle were determined by the microsphere technique. Declipping caused MAP to fall from 167 +/- 5 to 108 +/- 5 mmHg (n = 10) with a concomitant fall in HR from 424 +/- 11 to 363 +/- 14 beats/min (P less than 0.01). The calculated vascular resistances fell in the intestinal and declipped renal vascular beds by 50-60% compared with sham-operated rats (P less than 0.01). However, vascular resistances remained unchanged in skeletal muscle and in the untouched kidney. This indicates that the reduction in flow resistance varies in the different vascular beds, presumably reflecting a mixture of suppressed sympathetic activity and direct vasodilatory actions induced by mechanisms activated upon reversal of two-kidney, one clip renal hypertension by renal artery declipping.

Animals↗
PubMed1986

[Interruption of the vena cava inferior. A comparative study of the Adams de Weese clip and the Kimray Greenfield filter].

Efficacy of two methods for interruption of inferior vena cava was compared after insertion of 95 Adams de Weese clips by the sub or trans-peritoneal route and of 72 Greenfield filters usually by a jugular approach. Introducing Greenfield's filter to produce caval interruption did not require modification of operative indications. In contrast, it allowed caval blockade to be performed in more elderly patients, generally in a poorer condition, at the price of higher mortality, due more to the clinical circumstances of the interruption rather than the caval blockade itself. Postoperative follow up showed fewer caval thromboses after Greenfield's filter (15%) than after the pericaval clip (35%).

Adult↗
PubMed1987

Spectral analysis of cough sounds recorded with and without a nose clip.

The voluntary cough sounds of healthy volunteers, patients with chronic rhinitis, chronic rhinitis with bronchial asthma and asthma were recorded with and without a nose clip. A gated series of signals of the first cough sound lasting 200 ms was analysed by a system with a 20 ms delay of the first signal. In the case of filtered cough sounds, low-cut digitally, the mean values of averaged spectra of the healthy volunteers showed a first peak around 350 Hz, similar to the expiratory spectra of respiratory sounds. Second and third harmonics were also identified. The mean values of averaged spectra from the patients with airway disease differed significantly in the range of low frequency components. The upper airways work as narrow-band acoustic filters determining the harmonic contents of speech as well as those of cough sounds. To minimize these effects for acoustic analytical purposes, the application of a nose clip is suggested to find the cough harmonics related to those of pulmonary sounds. The voluntary cough sounds contain diagnostic information, but to build up a quantitative, diagnostic, decision-making system, further investigations as well as standardization of recording and analysis are necessary.

Adolescent↗
PubMed1987

The use of vascular clips to minimize blood loss in colpourethropexy.

A serious intraoperative and postoperative complication associated with colpourethropexy as described by Burch and Tanagho and others is hemorrhage. We performed the Tanagho modification of the Burch procedure in 13 patients, as the sole procedure in the treatment of genuine stress incontinence. Vascular clips were used to circumscribe the fat overlying the anterior part of the vaginal wall, thereby allowing en bloc resection of the vascular fat pad. Suspensory sutures of 1-0 Vicryl (polyglactin 910) were placed; no retroperitoneal drains were used. The blood loss was estimated to be less than 50 milliliters in ten instances and less than 75 milliliters in three. The average hospital stay was 4.2 days. All of the patients were given antibiotic prophylaxis and were discharged home with suprapubic drainage of the bladder. There were no intraoperative or postoperative complications. Thus, one of the serious complications of colpourethropexy can be avoided by using vascular clips to facilitate the removal of the periurethral and paravesical fat from the anterior part of the vaginal wall.

Adipose Tissue↗
PubMed1985

[Gallstone formation following transmural migration of a surgical clip in the bile ducts. Case report].

Foreign bodies as a nucleus for precipitation of gall-stones are not frequently observed. The combination of primary immigrated foreign bodies into the bile ducts and following encasing by a gall-stone could be even more rarely found. A case report is presented concerning a patient, in whom a hemo-clip was fixed away from the bile-ducts in connection with a cholecystectomy and revision of the common bile-duct. After hospital admission because jaundice in the PTC was found a prepapillary concrement with a central hemo-clip, which has served as a nucleus for precipitation after transmural immigration.

Cholecystectomy↗