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At least 1,225 records · Page 68Linked to original sources
PubMed1986

Efficacy and stability of two chlorine-containing antiseptics.

Dakin's solution and a chloroxydizer in a hypertonic sodium chloride solution were tested for bacteriological and clinical effectiveness and stability. No real difference in effectiveness was observed between the two products; however, only the chloroxydizer showed satisfactory stability at 150 days under the test storage conditions.

Anti-Infective Agents, Local↗
PubMed1979

[Antiseptics and aseptics in changing times].

The history of wound healing is a series of errors not to be understood today. Historical aspects of anti- and aseptis are dealt with; the merits of Ignaz Semmelweis, Joseph Lister and Robert Koch are stressed; conclusions for the time being are drawn.

Antisepsis↗
PubMed1985

[Plasmid resistance to antiseptics. Demonstration of methods].

Susceptibility to chlorhexidine, benzalkonium chloride and mercury chloride was studied for 70 Gram negative strains (56 Enterobacteriaceae and 14 Pseudomonas aeruginosa) recovered from humans or animals. Minimal inhibitory concentration (MIC) was determined on solid agar (replica plating) and in a liquid medium (laser nephelometry). For resistant strains, plasmidic mediation was looked for using conjugation. Isolation of lysates by the miniprep analytic method and physicochemical characterization of plasmids by agar electrophoresis were carried out using conjugative strains. MICs obtained using the two methods differed by one dilution at the most. Both methods yielded reproducible results. Regardless of the origin of strains, a resistant population was identified only for mercury chloride. This resistance was plasmid-mediated and transferred singly or associated with resistance to other antibiotics.

Anti-Infective Agents, Local↗
PubMed1985

[Effect of the antiseptic merthiolate and its derivatives on fungi causing deterioration].

The fungistatic activity of merthiolate and its two polymerous derivatives have been investigated using as test cultures fungi producing deterioration. The fungicides sorbtion dynamics by the fungus micelium have been studied, toxicity and inhibition rate of the catalase from different sources have been evaluated. The polymerous derivatives have been found to maintain high fungistatic activity of merthiolate, but possess less toxicity. The sorbtion of the polymerous derivative by the fungal mycelium takes place more effectively than the merthiolate sorbtion. The probable reasons of the high activity of the merthiolate polymerous derivatives are under discussion.

Absorption↗