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At least 1,207 records · Page 67Linked to original sources
PubMed2005

The prevalence of psychological and psychiatric sequelae of cancer in the elderly - how much do we know?

INTRODUCTION: Ageing is the greatest single risk factor for cancer but there is a dearth of systematically reviewed data on the psychological and psychiatric sequelae in elderly cancer patients. The aim of this paper is to review the current literature on these issues. MATERIALS AND METHODS: Multiple searches using Medline (1970 to 2003), PsycInfo (1970 to 2003), CINAHL (1982 to 2003), EMBASE Psychiatry (1992 to 2003) and Cochrane Research Database were carried out. Additional searches were made using the reference lists of published papers and chapters. RESULTS: Most of the studies were cross-sectional in nature. The few longitudinal studies had fairly short follow-up periods. Overall, the available evidence suggests that up to a third of elderly cancer patients may experience psychological distress. The psychological impact of cancer on the elderly was less adverse or similar compared with younger patients. There were only limited studies that specifically addressed the prevalence of psychiatric disorders in elderly cancer patients, which suggested that the prevalence for clinically significant depression could range from 3% to 25%. Organic mental disorders were more prevalent in the older group. CONCLUSIONS: This review suggests that the psychological impact of cancer is less negative in the elderly compared to younger patients. As for the prevalence of psychiatric disorders in elderly cancer patients, this review suggests that it is an unanswered question with a dearth of published data, with most work either based only on clinical or hospital samples or not solely on the elderly.

Aged↗
PubMedDate not supplied

Surgical treatment of sequelae of fractures of the proximal third of the humerus. The role of osteotomies.

Between 1996 and 2003 a total of 19 humeral head osteotomies were performed to treat post-traumatic malunion of the proximal humerus. Mean age was 46 years, ranging from 17 to 71 years. The period of time between traumas and surgeries ranged from 6 to 22 months. Osteotomy procedure was as follows: one after two-part fracture of the greater tuberosity, three after two-part fracture of the surgical neck, five after three-part fracture of the greater tuberosity, eight after four-part fracture, two after complex head splitting fracture, one after two-part fracture with anterior dislocation. Three different types of osteotomies were performed: osteotomy of the humeral neck for varus deformity, isolated osteotomy of the greater tuberosity, and a new osteotomy technique (two-plane and three-plane osteotomy) for three- and four-fragment fracture sequelae. At the time of follow-up evaluation, all 19 patients were questioned regarding pain and function. Excellent results in 14 patients and satisfactory results in 5 were obtained. None of the patients required revision surgery. Findings were recorded using the Constant rating scale. All patients had had significant pain relief after shoulder osteotomy. Range of motion was increased in all patients treated by osteotomy. The success of osteotomy in these cases was based on: patient selection, extensive preoperative evaluation, surgical technique and postoperative rehabilitation.

Adolescent↗
PubMed2006

Prospective evaluation of hepatitis B, C and HIV infections as possible sequelae of antineoplastic treatment in paediatric sarcoma patients: a report from the Late Effects Surveillance System.

Cancer therapy and supportive measures entail the risk of infection with hepatitis B (HBV), hepatitis C (HCV) or human immunodeficiency virus (HIV). The objective of this analysis was to establish the incidence of infections with these viruses during antineoplastic treatment in our paediatric sarcoma patients, who are being followed-up within the Late Effects Surveillance System (LESS), which prospectively registers sequelae of therapy for Ewing's-, soft tissue- and osteosarcoma in patients treated in Germany, Austria and Switzerland within the trials EICESS-92/EURO-E.W.I.N.G.-99, CWS-96/CWS-2002P and COSS-96. We studied 264 eligible relapse-free paediatric patients [median age at diagnosis 14.3 (IQR 11.1-16.4) years], treated from January 7, 1998 until April 24, 2004. According to the LESS protocol, serological examinations for HBV, HCV and HIV were scheduled 4 weeks and 6 months after cessation of antineoplastic treatment. The median follow-up was 20.6 (IQR 12.4-26) months. None of the patients was reported to have acquired HBV, HCV or HIV during antineoplastic treatment. Blood donor screening and prophylactic measures employed in Germany, Austria and Switzerland to prevent infections of cancer patients with HBV, HCV and HIV seem to be very effective, having fully prevented new infections in this large cohort of paediatric sarcoma patients.

Adolescent↗
PubMed2006

[Noninvasive positive pressure ventilation in patients with acute exacerbations of pulmonary tuberculosis sequelae].

To clarify whether noninvasive positive pressure ventilation (NPPV) is effective in patients with acute exacerbations of pulmonary tuberculosis sequelae (PTS), 50 PTS patients (66 episodes) without long-term domiciliary noninvasive ventilation were studied, retrospectively. The average values (SD) of their pulmonary function tests and arterial blood gases were as follows; %predicted VC = 31.4 (8.4)%, pH = 7.29 (0.06), PaCO2 = 91.8 (19.7) mmHg, and PaO2 = 64.2 (20.3) mmHg. The probability of avoiding endotracheal intubation and recovering from an acute exacerbation with NPPV (NPPV success rate) was 92% as a whole. NPPV success rates according to the causes of deterioration were as follows; 96% in 26 episodes with only a simple right heart failure, 93% in 29 episodes with airway infectious diseases, 75% in eight episodes with pneumonia and/or acute respiratory distress syndrome. Moreover, the NPPV success rate of eight episodes in coma or semicoma was 88%. Most patients were treated in respiratory wards rather than intensive care units. Out of 46 patients who recovered from an acute exacerbation, 41 finally received domiciliary NPPV. In facilities where staff are well-trained for an acute NPPV, patients with exacerbations of PTS can be treated as successfully with NPPV as patients with COPD.

Aged↗
PubMed1991

[A comparative evaluation of methods for treating the sequelae of fractures and dislocations of the bones of the hand].

A comparative clinical investigation of effectiveness of different methods of treatment of sequelae of injuries of the hand bones and joints in 159 patients was carried on. Traditional methods of treatment and devices for external fixation were used. An analysis of long-term results of treatment of 145 patients has shown that methods of external fixation by compressive-distraction and hinge-distraction devices are most effective.

Adult↗
PubMed2006

Post-operative sequelae of lower third molar removal: a literature review and pilot study on the effect of Covomycin D.

Pain, swelling and dry socket formation commonly follow third molar surgery. The objective was to investigate the effect of intrasocket Covomycin D, an antibiotic/anti-inflammatory medication, on pain, swelling and dry socket following lower third molar removal. Nineteen subjects had bilateral lower third molars removed. The patients were blinded to the side of medication; the opposite side acted as the control; post-operatively a pain visual analogue scale was completed, the side of the worst swelling and the incidence of dry socket noted. The data was analysed using the Wilcoxons matched pairs signed ranks test. Results showed that the pain score was lower for the medicated side in 11 patients on day one and in 16 patients over the six day post-operative period (p < 0.6). The swelling was less on the medicated side in fourteen patients. Three dry sockets developed in non-medicated sockets. In conclusion this study shows that the use of intra-socket Covomycin D favourably influences post-operative sequelae following lower third molar removal.

Administration, Topical↗
PubMed2006

Incidence of male childhood sexual abuse and psychological sequelae in disaster workers exposed to a terrorist attack.

This study documents the prevalence of male childhood sexual abuse (CSA) and psychological sequelae in a sample of disaster workers deployed to the World Trade Center (WTC) site following the September 11, 2001 terrorist attack. There are limited data on male CSA and its psychological impact, especially on a large non-treatment seeking sample. As part of a mandatory medical screening program, workers were assessed with well-validated and widely used clinician interview and self-report measures following their involvement in the restoration of services to Ground Zero and surrounding areas of lower Manhattan. Frequency of CSA measured by the Traumatic Events Interview (TEI) was 4.3% (n = 92). Clinician interview and self-report data were analyzed using t-tests, revealing statistically significant relationships (but not clinically meaningful scores) between CSA and scores on the CAPS, PCL, BDI, STAXI, and SDS. Further analyses revealed that individuals endorsing CSA were three-times more likely to score high (vs. low) on the BDI and CAPS. Since disaster workers traditionally summon images of strength and mastery, professionals may overlook CSA and symptoms of depression and PTSD in this population.

Adult↗
PubMed1975

The effect of dengue virus infection on the clinical sequelae of Japanese encephalitis: a one year follow-up study in Thailand.

In order to determine if prior dengue virus infection reduces the severity of Japanese encephalitis (JE), we examined 127 patients hospitalized during the 1970 JE epidemic in the Chiangmai and Lampang Valleys of northern Thailand. Patients were studied during the first 30 days after onset of JE; 120 of these patients were examined one year later for residual neurologic sequelae. About 21% of patients had serological evidence of a prior dengue virus infection. Morbidity and mortality in patients with and without prior dengue virus experience were compared. These comparisons were made within two age groups to exclude differences due to age alone;

Adolescent↗
PubMed1991

[A case report of a patient with sequelae of SMON and painful tonic seizure].

We reported a case with sequelae of SMON and painful tonic seizure (PTS). The patient was a 50-year-old woman. Onset of SMON was when she was 28 years old. She has been suffering from decreased sensation and dysesthesia below C8 cord level to a severe degree, gait disturbance to a moderate degree and visual disturbance to a slight degree. Since January 1990, she experienced stereotyped tonic seizures of all extremities and trunk without consciousness disturbance, preceded by tingling sensation ascending from bilateral distal legs, several times a day. During hospitalization, epilepsy, tetany and multiple sclerosis were ruled out and its seizures were completely depressed by oral administration of a small amount of carbamazepine. PTS which is said to be characteristic of multiple sclerosis is seldom found in SMON patients. This is a very important and interesting case to suggest a certain relation between the mechanism of PTS and the cord lesions of SMON.

Female↗
PubMed1991

[Neurological sequelae caused by surgical procedures during adenoidectomy under anesthesia].

A five-year old boy with good risk was anesthetized with nitrous-oxide and halothane under orotracheal intubation for adenoidectomy and tubing of bilateral middle-ear cavities. Patient was on supine position with extension of neck. A mouth-gag was applied and the pharynx was packed with gauze. After long unskilled surgical procedures, severe neurological complications which were initiated with severe arrhythmias and followed by signs of paralysis of bilateral IX, X, XI, XII cranial nerves at their nuclei in medulla oblongata, were observed during the post-anesthetic period. The patient was saved with neurological sequelae of the cranial nerves and is alive after 6 years from the incident. The causes of this complications were discussed.

Adenoidectomy↗
PubMed1991

[Neuropsychological sequelae after electric accidents].

No investigations have been found in the literature which document how many individuals develop neuropsychological and neuropsychiatric dysfunctions following electric shock. Three cases are reviewed in this article where patients developed neuropsychological dysfunction after electric accidents. The first case report describes a man who developed an amnestic syndrome followed by personality changes and diffuse anxiety after an electric accident. The two other case reports are comparable to the post-concussional syndrome. The patients had difficulty in concentration, psychosomatic symptoms and anxiety reactions. On the basis of the case reports described here, it is important to emphasize that manifest or discrete neurological, neuropsychological and neuropsychiatric dysfunctions may occur as sequelae of electric shock. It is therefore of significance to submit patients of this type to neurological examination and neuropsychological and personality psychological investigations in order to reveal possible neurological and psychological disturbances.

Accidents, Occupational↗
PubMed1991

Psychological sequelae in stroke patients.

The psychological sequelae of depression, anxiety and dementia are discussed as they affect the stroke sufferer. The author discusses the management options available to deal with these problems.

Anxiety Disorders↗
PubMed1991

[Neuropsychological sequelae in children treated for brain tumor].

Treatment modalities of childhood brain tumors are associated with adverse neuropsychologic sequelae that may be manifested years after therapy. Based on recent published studies, the authors review the etiological factors, the symptoms and the evolutive features of these disorders and their management.

Brain Neoplasms↗
PubMed1991

[Surgical treatment of sequelae of injuries of the thoracolumbar spine].

The authors describe surgical techniques used in 48 patients with sequelae of injuries of the thoracolumbar spine and the achieved results. Twenty-one patients were treated by an anterior operation, 14 by posterior operation and 13 a combination of both. The anterior operation involved 1) simple stabilization by autografts or 2) release, correction of the kyphosis and fusion and 3) elimination of the affected body of the vertebra and replacement by a massive allograft. If reliable stability was not achieved, instrumentation was added. In posterior operation they always stabilized the spine by instrumentation and added fusion. In the remaining patients they combined the posterior and anterior operation. The anterior operations were, if necessary, supplemented by decompression, when using the posterior approach they decompressed by the posterolateral route. As to complications which called for re-operation, instrumentation failed once and twice a pseudoarthrosis was repaired. Pain disappeared or receded substantially in 86%. Of 30 patients with a partial nervous lesion 14 (47%) improved, in two slight deterioration occurred.

Adolescent↗
PubMed1991

Assessing risk for pelvic inflammatory disease and its sequelae.

To assess the risk for pelvic inflammatory disease (PID), a practitioner must evaluate the likelihood that a woman has PID or will be exposed to a sexually transmitted disease causing PID. Successful risk assessment depends on accurate information about variables influencing risk of PID. To determine the current state of knowledge about PID risk variables, we examined data in published reports. Data on each risk variable were scrutinized to discern which link(s) in the PID risk chain it affects (acquisition of a sexually transmitted disease, development of PID, or development of PID sequelae) and whether it is a risk marker or a risk factor. Most PID risk variables, particularly sexual behaviors, are associated with acquisition of a sexually transmitted disease, rather than development of PID itself. With the exception of age, demographic and social indicators of risk appear to be risk markers, while contraceptive practices appear more often to be risk factors than risk markers. Additional data are needed for most PID risk variables confidently to categorize them as risk factors. Enough information is available, however, to begin assessing risk for PID, so that appropriate counseling can ensue and timely diagnosis can be made.

Age Factors↗
PubMed1991

[Latissimus dorsi muscle flap for autologous myoplasty in children with sequelae to obstetric paralysis of the Duchenne-Erb type].

Within 1987-1989, surgical correction of sequelae to obstetrical paralysis of an upper extremity of the Duchenne-Erb type was accomplished in 26 children. In 11 cases, the operations of transposition and lengthening of the adductor brachial muscles were supplemented with a non-free transfer of a thoracico-dorsal flap on a neurovascular bundle to the position of a musculus deltoideus. With the aim of active functional influencing on a myotransplant at the early postoperative period, the neural stimulation and adaptive bioregulation with the outer feedback were used. For control, the continuous electroneuromyography was used. A good functional result was obtained.

Adolescent↗
PubMed1991

Morphological sequelae of intracameral hydrogen peroxide after inhibition of glutathione synthesis.

The morphological sequelae of intracameral injections of hydrogen peroxide on the corneal endothelium were examined under different conditions. In animals pretreated with either intravenous 3-aminotriazole (3AT) alone, to suppress catalase activity, or intravitreal buthionine sulfoximine alone (BSO), to inhibit gamma-glutamyl synthetase activity, the endothelium was normal. The intracameral administration of 10 microliters of 10 mM hydrogen peroxide caused no response after 3AT and some small morphological but not physiological changes after BSO pretreatment. The intracameral injection of 10 microliters of 25 mM hydrogen peroxide caused no additional change in 3AT pretreated rabbits, but caused substantial morphological and physiological changes in BSO pretreated rabbits. The correlation between the present morphological changes and those seen earlier in physiological studies is excellent. The data confirm that the glutathione redox system may be more important than catalase in maintaining the integrity of the corneal endothelium at low aqueous humor concentrations of hydrogen peroxide while catalase assumes greater importance at higher peroxide concentrations.

Amitrole↗
PubMed1991

Sequelae after infection with Trichinella spiralis: a prospective cohort study.

It is still a matter of debate whether or not infection with Trichinella spiralis is followed by long lasting sequelae. A common source epidemic of trichinosis which occurred in Bitburg, FRG, in October 1982 gave us the opportunity of performing a controlled cohort study (171 patients and 51 controls). 145 patients and 44 controls completed the 3 year follow-up. Complaints persisted in 36% of patients aged less than 30 years and in 100% of patients aged greater than 50 years. Complaints in order of frequency were: muscular complaints 84%, ocular complaints 63%, cardiac complaints 48%, cephalgia 43%, neurological complaints 35%, gastrointestinal complaints 18%, m fatigue and weakness 18%, oedema 12% and fever less than 1%. IgG antibodies to T. spiralis were still present in all but 5 patients 3 years after infection. IgM antibodies were either low or absent. In our patients the frequency and pattern of complaints and the correlation to the specific antibody response provide evidence that trichinosis causes long-lasting disease. Yet, from our data we were unable to draw conclusions as to the causative pathophysiological mechanisms.

Adolescent↗