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Analysis of a correlation-based model for the development of orientation-selective receptive fields in the visual cortex.

We analyse a model for the development of orientation-selective receptive fields of simple cells in a locally connected network of cortical neurons. The Hebbian learning rule that underlies the development is described by a linear differential equation. The structure of the emerging cortical map can be predicted by deriving the eigenfunctions corresponding to the leading eigenvalues of the associated matrix. We show that the receptive fields have the typical form of a wavelet. Mathematically, receptive fields are given by a Hermitian polynomial with Gaussian cut-off and a phase factor. Both the phase of the wavelet and the orientation are changing periodically along the surface of the cortical map as suggested by previous simulation studies and as also found in experiments. In order to get orientation-selective receptive fields, the spatial correlation function of the inputs that drive the development must have a zero crossing.

Algorithms↗

Quantification of ECG late potentials by wavelet transformation.

Late potentials of preprocessed ECG recordings from patients with sustained ventricular tachycardia and healthy control subjects are investigated by the wavelet transformation. The advantages of this non-stationary signal processing method are discussed in comparison with FFT spectrograms of artificial test signals. The energy distribution plots of these wavelet transformed test signals demonstrate the superiority in detection accuracy and frequency resolution compared with the corresponding spectrograms. For this reason a quantitative discrimination between the two clinical groups of patients and healthy subjects was performed by calculating the scalograms of the wavelet transformed ECG signals in the time-frequency plane. The energy in the frequency band of 100-300 Hz during the last time segment of the QRS complex yielded best classification results.

Action Potentials↗

Automatic measure of the split in the second cardiac sound by using the wavelet transform technique.

This paper is concerned with the identification and automatic measure of the split in the second heart sound (S2) of the phonocardiogram signal (PCGs) for normal or pathological case. The second heart sound S2 consists of two acoustic components A2 and P2, the former is due to the closure of the aortic valve and the latter is due to the closure of the pulmonary valve. The aortic valve usually closes before the pulmonary valve, introducing a time delay known as "split". A automatic technique based on the discrete wavelet transform (DWT) and the continuous wavelet transform (CWT) is developed in this paper to measure the split of the second cardiac sound (S2) for the normal and pathological cases of the PCG signals. To quantify the splitting, the two components in S2 (i.e. A2 and P2) are identified and, the delay between the two components can be estimated. It is shown that the wavelet transform can provide best information and features of the split of S2 and the major components (A2 and P2) and consequently aid in medical diagnosis.

Aortic Valve↗

Quantitative EEG and effect of hypothermia on brain recovery after cardiac arrest.

In this paper, we provide a quantitative electroencephalogram (EEG) analysis to study the effect of hypothermia on the neurological recovery of brain after cardiac arrest. We hypothesize that the brain injury results in a reduction in information of the brain rhythm. To measure the information content of the EEG a new measure called information quantity (IQ), which is the Shannon entropy of decorrelated EEG signals, is developed. For decorrelating EEG signals, we use the discrete wavelet transform (DWT) which is known to have good decorrelating properties and to show a good match to the standard clinical bands in EEG. In measuring the amount of information, IQ shows better tracking capability for dynamic amplitude change and frequency component change than conventional entropy-based measures. Experiments are carried out in rodents (n = 30) to monitor the neurological recovery after cardiac arrest. In addition, EEG signal recovery under normothermic (37 degrees C) and hypothermic (33 degrees C) resuscitation following 5, 7, and 9 min of cardiac arrest is recorded and analyzed. Experimental results show that the IQ is greater for hypothermic than normothermic rats, with an IQ difference of more than 0.20 (0.20 +/- 0.11 is 95% condidence interval). The results quantitatively support the hypothesis that hypothermia accelerates the electrical recovery from brain injury after cardiac arrest.

Algorithms↗

Wavelet decomposition of cardiovascular signals for baroreceptor function tests in pigs.

In this paper, the discrete wavelet transform (DWT) was applied to analyze the fluctuations in RR interval and systolic arterial pressure (SAP) recorded from eight alpha-chloralose anesthetized pigs. Our aim was to characterize the autonomic modulation before and after cardiac autonomic blockade and during baroreflex function tests. The instantaneous power of decomposed low-frequency (LF) and high-frequency (HF) components was used for a time-variant spectral analysis. Our results suggested that transient events and changes in autonomic modulation were detected with high temporal resolution. A nonlinear relationship between RR interval and SAP during pharmacologically induced changes in blood pressure was found, when the superimposed effect of respiratory sinus arrhythmia was removed. In addition, the baroslopes were nearly linear when both the LF and HF components were removed using DWT decomposition.

Algorithms↗

Aspects of signal-dependent noise characterization.

An automated method is presented for analyzing signal-dependent noise. Signal-dependent noise is present in many types of data-acquisition processes and has been investigated by other researchers with various methods. Regardless of the noise analysis methods, often the starting point is based on a particular signal-dependent noise model, which also forms the basis for our study. The approach determines whether the estimated noise variance is dependent on the signal by approximating the functional relation within the constraints of the assumed signal-noise model. The method relies on the Fourier attributes of the signal and noise and uses the wavelet expansion for separating these components. The technique does not rely on the underlying noise and signal probability distributions. Two-dimensional simulations as well as mammography data are used to illustrate the merits of the approach.

Journal Article↗

Progressive quantized projection approach to data hiding.

A new image data-hiding technique is proposed. The proposed approach modifies blocks of the image after projecting them onto certain directions. By quantizing the projected blocks to even and odd values, one can represent the hidden information properly. The proposed algorithm performs the modification progressively to ensure successful data extraction without the need for the original image at the receiver side. Two techniques are also presented for correcting scaling and rotation attacks. The first approach is an exhaustive search in nature, which is based on a training sequence that is inserted as part of the hidden information. The second approach uses wavelet maxima as image semantics for rotation and scaling estimation. Both algorithms have proved to be effective in correcting rotation and scaling distortion.

Algorithms↗

Image registration using the Walsh transform.

This paper presents a new algorithm which can be used to register images of the same or different modalities, e.g., images with multiple channels, such as X-rays, temperature or elevation, or simply images of different spectral bands. In particular, a correlation-based scheme is used, but instead of gray values, it correlates numbers formulated by different combinations of the extracted local Walsh coefficients of the images. Each image patch is expanded in terms of Walsh basis functions. Each Walsh basis function can be thought of as measuring a different aspect of local structure, e.g., horizontal edge, corner, etc. The coefficients of the expansion, therefore, can be thought of as dense local features, estimating at each point the degree of presence of, for example, a horizontal edge, a corner with contrast of a certain type, etc. These coefficients are normalized and used as digits in a chosen number system which allows one to create a unique number for each type of local structure. The choice of the basis of the number system allows one to give different emphasis to different types of local feature (e.g., corners versus edges), and, thus, the method we present forms a unified framework in terms of which several feature matching methods may be interpreted. The algorithm is compared with wavelet and contour based approaches, using simulated and real images. The two images are assumed to differ from each other by a rotation and a translation only.

Algorithms↗

Analysis and modeling of broadband airgun data influenced by nonlinear internal waves.

To investigate acoustic effects of nonlinear internal waves, the two southwest tracks of the SWARM 95 experiment are considered. An airgun source produced broadband acoustic signals while a packet of large nonlinear internal waves passed between the source and two vertical linear arrays. The broadband data and its frequency range (10-180 Hz) distinguish this study from previous work. Models are developed for the internal wave environment, the geoacoustic parameters, and the airgun source signature. Parabolic equation simulations demonstrate that observed variations in intensity and wavelet time-frequency plots can be attributed to nonlinear internal waves. Empirical tests are provided of the internal wave-acoustic resonance condition that is the apparent theoretical mechanism responsible for the variations. Peaks of the effective internal wave spectrum are shown to coincide with differences in dominant acoustic wavenumbers comprising the airgun signal. The robustness of these relationships is investigated by simulations for a variety of geoacoustic and nonlinear internal wave model parameters.

Journal Article↗

Modulating effect of respiration on atrioventricular conduction time assessed using PR interval variation.

Respiratory sinus arrhythmia (RSA) is the variation of heart rate (or RR interval) in phase with respiration and has been extensively studied. However, the effect of respiration on atrioventricular conduction delay (and hence PR interval length) has not yet received much attention. This work reports on measurements of respiration and associated RR and PR variability, in 11 subjects, assessed through surface electrocardiogram measurements, for both paced and spontaneous respiration in the supine position. A wavelet-based approach was used to extract RR and PR intervals. The accuracy of RR and PR interval measurement was consistent with previously published work. Respiratory atrioventricular conduction delay variability (RCV) was assessed using three techniques: spectral, peak-to-trough and cosinor methods. All measures showed statistically significant variations in PR interval due to respiration during paced respiration at 6 min(-1). Of the three measures, cosinor analysis was most reliable in highlighting RCV. Using this measure, statistically significant RCV was seen in ten out of the 11 subjects during paced respiration. The magnitude of the variability was estimated as +/- 5.9% of the mean PR interval. In spontaneous respiration, statistically significant RCV was seen in approximately half of the subjects, with an estimated variability of +/- 1.5%. As a control, statistically significant values for RSA were also obtained from the same data, which agreed with previously published measurements. It was concluded that respiration does indeed modulate atrioventricular conduction delay, deep breathing in the supine position accentuates this effect, and cosinor analysis provides a reliable means for quantifying this effect.

Adult↗

Dissociated changes of somatosensory evoked low-frequency scalp responses and 600 Hz bursts after single-dose administration of lorazepam.

Electrical stimulation of upper limb nerves allows one to record two types of scalp responses, that is conventional low-frequency somatosensory evoked potentials (SEPs), and bursts of high-frequency (about 600 Hz) wavelets. To further clarify the functional meaning of both types of responses, we investigated whether changes of GABAergic drive could cause significant modifications of conventional as well as high-frequency SEPs. We recorded median nerve SEPs from six healthy volunteers before and after a single oral administration of lorazepam. In order to explain scalp SEP distribution before and after lorazepam administration, we performed the brain electrical source analysis of raw data. After lorazepam administration, conventional scalp SEPs showed a significant amplitude decrease of all cortical components including the primary N20/P20 response, while the subcortical P14 response remained substantially unchanged. Similarly, dipolar analysis showed a significant strength decrease of all cortical dipoles, whereas the strength of both subcortical dipoles (possibly located at the level of the brainstem and thalamus, respectively) remained unchanged. By contrast, no significant changes of high-frequency SEPs were induced by drug intake. Therefore, our findings suggest that the inhibitory effect induced by lorazepam mainly affects intracortical circuitry. Tonic increase of the inhibitory drive, possibly mediated by GABAA receptors, can account for the reduced activity of first order deep spiny neurons generating the primary N20/P20. Conversely, intrinsic firing properties of the cell population generating high-frequency SEP responses are unaffected by the increase of GABAergic drive. This finding lends further substance to the hypothesis that conventional and high-frequency SEPs are generated by different cell populations.

Adult↗

Single-trial event-related potentials with wavelet denoising.

The application of a recently proposed denoising implementation for obtaining event-related potentials (ERPs) at the single-trial level is shown. We study its performance in simulated data as well as in visual and auditory ERPs. For the simulated data, the method gives a significantly better reconstruction of the single-trial event-related responses in comparison with the original data and also in comparison with a reconstruction based on conventional Wiener filtering. Moreover, with wavelet denoising we obtain a significantly better estimation of the amplitudes and latencies of the simulated ERPs. For the real data, the method clearly improves the visualization of both visual and auditory single-trial ERPs. This allows the calculation of better averages as well as the study of systematic or unsystematic variations between trials. Since the method is fast and parameter free, it could complement the conventional analysis of ERPs.

Artifacts↗

Can ultrasound predict histological findings in regenerated cartilage?

OBJECTIVE: To evaluate regenerated articular cartilage quantitatively by introducing an ultrasonic probe into the knee joint under arthroscopy and analysing the A-mode echogram by means of wavelet transformation. METHODS: Three experimental rabbit models (spontaneous repair model, large cartilage defect model, treatment model) were examined using our ultrasonic evaluation system and a histological grading scale. From resulting wavelet map, the percentage of maximum magnitude was selected as the quantitative index of the ultrasonic evaluation system. RESULTS: The percentage maximum magnitude in the spontaneous repair model was 61.1%, that in the large defect model was 29.8% and that in the treatment model was 36.3%. There was modest correlation between the percentage maximum magnitude and the histological grading scale (r = -0.594) CONCLUSION: Our findings indicate that ultrasound analysis can predict the microstructure of regenerated cartilage.

Animals↗

Effect of CT image compression on computer-assisted lung nodule volume measurement.

PURPOSE: To evaluate the effect of two-dimensional wavelet-based computed tomographic (CT) image compression according to the Joint Photographic Experts Group (JPEG) 2000 standard on computer-assisted assessment of nodule volume. MATERIALS AND METHODS: This HIPAA-compliant study was approved by the research board at the authors' institution; patients' informed consent was not required. Fifty-one nodules in 23 patients (seven men, 16 women; mean age, 59 years; age range, 39-75 years) were selected on low-dose CT scans that were compressed to levels of 10:1, 20:1, 30:1, and 40:1 by using a two-dimensional JPEG 2000 wavelet-based image compression method. Nodules were classified according to size (< or = 5 mm or > 5 mm in diameter), location (central, peripheral, or abutting pleura or fissures), and attenuation (solid, calcified, or subsolid). Regions of interest were placed on the original images and transposed onto compressed images. Nodule volumes on original (noncompressed) and compressed images were measured by using a computer-assisted method. A mixed-model analysis of variance was conducted for statistical evaluation. RESULTS: Nodule volumes averaged 388.1 mm3 (range, 34-3474 mm3). There were three calcified, 33 solid noncalcified, and 15 subsolid nodules (13 with ground-glass attenuation). Average volume decreased with increasing compression level, to 383 mm3 (10:1), 370 mm3 (20:1), 360 mm3 (30:1), and 354 mm3 (40:1). No significant difference was identified between measurements obtained on original images and those compressed to a level of 10:1. Significant differences were noted, however, between original images and those compressed to a level of 20:1 or greater (P < .05). Compression level significantly interacted with nodule size, location, and attenuation (P < .001). The effect of compression was greater for nodules with ground-glass attenuation than for those with higher attenuation values. The difference in mean volumes between original images and those compressed to a level of 20:1 was 34.9 mm3 for nodules with ground-glass attenuation, compared with 8.3 mm3 for higher-attenuation nodules, a 4.2-fold difference. CONCLUSION: Nodule volumes measured on images compressed to a level of 20:1 differed significantly from those measured on noncompressed images, especially for nodules with ground-glass attenuation. This difference could affect the assessment of nodule change in size as measured with computer-assisted methods.

Adult↗

Comparison of the fast Fourier transform and continuous wavelet transform for examining mechanomyographic frequency versus eccentric torque relationships.

The purpose of this study was to compare the eccentric torque-related patterns for mechanomyographic (MMG) center frequencies (mean power frequency (MPF), median frequency (MDF), and average instantaneous mean power frequency (AIMPF)) determined by the fast Fourier transform (FFT) and continuous wavelet transform (CWT). Eight adults (mean+/-S.D. age=22.5+/-2.4 years) performed submaximal to maximal, eccentric isokinetic muscle actions of the biceps brachii on a Cybex 6,000 dynamometer. The mean MMG MPF, MDF, and AIMPF values for both the absolute and normalized data from 10 to 100% eccentric peak torque (PT) were highly intercorrelated at r=0.908-0.985. Linear models provided the best fit for the absolute MMG MPF (r=0.873), MDF (r=0.831), and AIMPF (r=0.924), as well as normalized MMG MPF (r=0.869), MDF (r=0.816), and AIMPF (r=0.920) versus percentage eccentric PT relationships. There were no significant differences (p>0.05) among the linear slope coefficients for the MMG MPF, MDF, and AIMPF versus percentage eccentric PT relationships for either the absolute or normalized data. These results suggested that Fourier or wavelet transform procedures can be used to examine the patterns of MMG responses during eccentric muscle actions of the biceps brachii.

Adult↗

Comparison of Fourier and wavelet transform procedures for examining mechanomyographic and electromyographic frequency versus isokinetic torque relationships.

The purpose of this study was to compare the isokinetic torque-related patterns for mechanomyographic (MMG) and electromyographic (EMG) center frequency [wavelet center frequency (CF), mean power frequency (MPF), and median frequency (MDF)] determined by the fast Fourier transform (FFT) and discrete wavelet transform (DWT). Ten adults [mean +/- SD age = 22.0 +/- 3.4 yrs] performed submaximal to maximal, isokinetic muscle actions of the biceps brachii on a Cybex II dynamometer. For both MMG and EMG, the CF, MPF, and MDF values were intercorrelated at (r = 0.91-0.98). Quadratic models provided the best fit for the absolute and normalized CF, MPF, and MDF versus isokinetic torque relationships for MMG (R2 = 0.67-0.83) and EMG (R2 = 0.72-0.90). The similarities among the CF, MPF, and MDF patterns suggested that Fourier or wavelet transform procedures can be used to examine the patterns of MMG and EMG responses during dynamic muscle actions.

Adult↗

Determination of carotid disease with the application of STFT and CWT methods.

In this study, Doppler signals were recorded from the output of carotid arteries of 40 subjects and transferred to a personal computer (PC) by using a 16-bit sound card. Doppler difference frequencies were recorded from each of the subjects, and then analyzed by using short-time Fourier transform (STFT) and the continuous wavelet transform (CWT) methods to obtain their sonograms. These sonograms were then used to determine the relationships of applied methods with medical conditions. The sonograms that were obtained by CWT method gave better results for spectral resolution than the STFT method. The sonograms of CWT method offer net envelope and better imaging, so that the measurement of blood flow and brain pressure can be made more accurately. Simultaneously, receiver operating characteristic (ROC) analysis has been conducted for this study and the estimation performance of the spectral resolution for the STFT and CTW has been obtained. The STFT has shown a 80.45% success for the spectral resolution while CTW has shown a 89.90% success.

Carotid Artery Diseases↗

A fast and efficient hybrid fractal-wavelet image coder.

The excellent visual quality and compression rate of fractal image coding have limited applications due to exhaustive inherent encoding time. This paper presents a new fast and efficient image coder that applies the speed of the wavelet transform to the image quality of the fractal compression. Fast fractal encoding using Fisher's domain classification is applied to the lowpass subband of wavelet transformed image and a modified set partitioning in hierarchical trees (SPIHT) coding, on the remaining coefficients. Furthermore, image details and wavelet progressive transmission characteristics are maintained, no blocking effects from fractal techniques are introduced, and the encoding fidelity problem common in fractal-wavelet hybrid coders is solved. The proposed scheme promotes an average of 94% reduction in encoding-decoding time comparing to the pure accelerated Fractal coding results. The simulations also compare the results to the SPIHT wavelet coding. In both cases, the new scheme improves the subjective quality of pictures for high-medium-low bitrates.

Algorithms↗