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PubMed2004

[Neonatal intensive care unit--therapeutical success and what next?].

The increasing number of successfully treated newborns with disturbances of the adaptive period can measure effectiveness of neonatal intensive care units (NICU). The authors summarized some health problems of the former NICU patients. Central nervous system (CNS) of the premature, especially low (LBW) and very low birth weight (VLBW) infant, is in serious danger of improper development. The lack of neurological disturbances in early infancy does not exclude further pathological events and such patients require long-term observation and follow-up. High-risk newborns are of great need of precise imaging and diagnosis of CNS, which should be performed before discharge. Early stimulation and developmental care program are the crucial points in the management of newborns with neurological abnormalities. Sensorial problems, especially the rate of vision and hearing impairments, can be significantly reduced when prophylactic schedule is applied. Both, etiological factors leading to respiratory insufficiency and some iatrogenic effects of the therapy, can influence respiratory system. Symptoms of different intensity--from sneezing caused by nasal mucous membrane edema to the severe forms of bronchopulmonary dysplasia (BPD)--may last for a long time and influence the child's general condition. The surgical closure of Botall's duct (persistent ductus arteriosus--PDA) usually normalizes the circulatory system. In serious heart defects or isolated shunt-type defects, the compensation of the circulatory system can easily be disturbed. Digestive tract problems belong to the two main groups: first--connected with the prematurity and immature interstitial functioning (necrotizing enterocolitis, digestive and absorption abnormalities, hepatic cholestasis), and second--caused by congenital defects requiring immediate surgical intervention. Despite different types of the diseases, the treatment and care have to be focused on necessary for the growing organism, optimal nutrients and calories uptake. Disturbances of social development, improper behavior, adaptation and emotional problems are mainly presented in VLBW patients and those with organic defects of the central nervous system.

Humans↗
PubMed1979

Edwin Chadwick, the market ideology, and sanitary reform: on the nature of the 19th-century public health movement.

This article is an attempt to place the origin of sanitary legislation in England, and its chief proponent, Edwin Chadwick, in the overall dynamics of 19th-century social development. It examines the public health movement in light of the transition of English society into the domination of the market ideology, and the effect that this had on health. Emphasis is placed on explaining the utilitarian movement, of which Chadwick was an instrumental part, and its role in promoting the market system through the enactment of the New Poor Law in 1834. The article suggests that the enactment of sanitary reform in the 1848 Public Health Act was the unplanned reaction to the detrimental effects that the market ideology had on health in the industrial centers. The main intent of this article is to go beyond the prevailing belief that sanitary reform was a humane contribution of publicly spirited men. It concludes that this state intervention was materially necessitated: it was forced by the contradictions inherent in the market system.

England↗
PubMed1999

Serum autoantibodies to brain in Landau-Kleffner variant, autism, and other neurologic disorders.

OBJECTIVE: Etiologically unexplained disorders of language and social development have often been reported to improve in patients treated with immune-modulating regimens. Here we determined the frequency of autoantibodies to brain among such children. DESIGN: We collected sera from a cohort of children with (1) pure Landau-Kleffner syndrome (n = 2), (2) Landau-Kleffner syndrome variant (LKSV, n = 11), and (3) autistic spectrum disorder (ASD, n = 11). None had received immune-modulating treatment before the serum sample was obtained. Control sera (n = 71) were from 29 healthy children, 22 with non-neurologic illnesses (NNIs), and 20 children with other neurologic disorders (ONDs). We identified brain autoantibodies by immunostaining of human temporal cortex and antinuclear autoantibodies using commercially available kits. RESULTS: IgG anti-brain autoantibodies were present in 45% of sera from children with LKSV, 27% with ASD, and 10% with ONDs compared with 2% from healthy children and control children with NNIs. IgM autoantibodies were present in 36% of sera from children with ASD, 9% with LKSV, and 15% with ONDs compared with 0% of control sera. Labeling studies identified one antigenic target to be endothelial cells. Antinuclear antibodies with titers >/=1:80 were more common in children with ASD and control children with ONDs. CONCLUSION: Children with LKSV and ASD have a greater frequency of serum antibodies to brain endothelial cells and to nuclei than children with NNIs or healthy children. The presence of these antibodies raises the possibility that autoimmunity plays a role in the pathogenesis of language and social developmental abnormalities in a subset of children with these disorders.

Antibodies, Antinuclear↗
PubMed1996

The influence of peer affiliation and student activities on adolescent drug involvement.

This study examined the importance of students' academic performance level and extracurricular activities as predictors of drug involvement relative to peer influence. Social development theory provided the theoretical rational for the study. Data were obtained from 2,229 randomly selected students in the eighth, tenth, and twelfth grades from seventeen school districts in northeastern Ohio. At all three grade levels, involvement in extracurricular activities and academic level were significantly correlated with students' gateway and hard drug use. Consistent with prior research, the strongest correlate of gateway and hard drug use across all grade levels was affiliation with drug-using friends. Having a job after school was marginally related to self-reported gateway drug use at grade level ten. Multiple regression analysis revealed that extracurricular involvement and academic performance level make small, but unique contributions to the prediction of adolescents' gateway drug use beyond affiliation with drug-using peers at all three grade levels. The findings of this study suggest that students' academic performance and extracurricular involvements are significantly related to adolescent gateway and hard drug use, but have less predictive significance relative to peer relationships.

Achievement↗
PubMed1986

[Chronic alcoholism--alcohol sequelae--causes of death].

In this study 444 chronic alcoholic patients, hospitalized at the beginning of this study, were followed up for 4 to 7 years (31). During this time 101 patients died (23.2%), with whom severeness of disease as well as the extent of social depravation could be identified as factors influencing mortality. Beginning in January of 1982 we investigated mortality of the population of a village with a similar socio-cultural background (working situation, rural population, wine-growing area). As it was possible to cooperate with the local general practitioner, who has been living and working in this village since 1946, knowing all the troubles and sorrows, we could get data of each person having died. We collected data on each dead of this village until we had 101 definitely not alcohol addicted cases as control group. For getting this number of cases we had to investigate data of 116 dead, because 15 of them met the diagnostic criteria for chronic alcoholism. Sociodemographic data, social development, diseases and causes of death were recorded in all groups of investigation. In the group of formerly hospitalized chronic alcoholic patients we found a preponderance of men as well as a significantly shorter life-time (alcoholic group: 50 +/- 9.8 years, control group 73.9 +/- 12.5 years). Besides alcohol misuse other factors influencing mortality could be elaborated (e. g. stressing or discriminating working situation, incontinuous and/or unsatisfying partnership, additional criminal acts etc.) separating the chronic alcoholic group (with former hospitalisation) from the control group in a significant way. Concerning the disease leading to death, chronic alcoholic patients more frequently had suffered from liver damage (with break of oesophagus blood vessels) as well as from auto-destructive behaviour patterns (like suicide, masked accidents) compared to the non-alcoholic group. This control group died significantly more frequent because of cardio-vascular diseases, often accompanied by cerebral deficits.

Adult↗
PubMed2004

[Comparing students in inclusive education to those in special schools: the view of parents of children with learning disabilities].

The paper presents the results of a survey of 755 parents of learning disabled children with certified special needs who either attended classes within regular education or special schools. All parents were involved in the decision on the school placement of their children. The experiences of 547 parents of learning disabled students in inclusive classes were contrasted with those of 207 parents of children in special schools. Besides a rather high satisfaction with previous school experiences of their children a number of differences between the two groups of parents could be observed. Parents of students in special schools viewed their children as rather little challenged by their educational requirements whereas those in inclusive education found their children to be overtaxed. The social development of the students in inclusive education was judged as more positive and, generally, a higher rate of parents of learning disabled students in inclusive classes were satisfied with their choice of the educational setting. Although the requirements for parental support concerning studying were higher in inclusive classes this cannot solely explain the differences of experiences with school. In a second step, satisfied parents were compared to dissatisfied parents. It could be found that the group of dissatisfied parents had to make their choice on the educational setting of their children under less favourable conditions and many could not accept that their child had been classified as having special needs. This applied to parents of students in inclusive education as well as to parents of children in special schools. Additionally, parents of students with German as a second language reported to be discontented more frequently. No significant discrepancies could be found between different grades or federal states with different quotas of inclusive education.

Attitude↗
PubMed2002

The anterior attention network: associations with temperament and neuroendocrine activity in 6-year-old children.

The capacity to effortfully control or regulate behavior is of central importance in social development. Individual differences in effortful control have been hypothesized to reflect biologically based, temperamental variation among children. Posner and Rothbart (1994, 1998) have argued that the anterior attention system, which includes areas of the midprefrontal cortex, underlies effortful control capabilities. Furthermore, components of the anterior attentional system are believed to be involved in the regulation of reactive, emotion-related system, such as the hypothalamic-pituitary-adrenocortical system. We assessed 58 six-year-old children's performance on neuropsychological tasks that have been found in functional imaging studies to involve the anterior brain regions which Posner (1995) describes as comprising the anterior attentional system. We then related performance on these tasks to delay of gratification tasks and parent report of temperament and behavior problems as well as home and laboratory cortisol levels. Results provide some support for Posner and Rothbart's model and suggest a relationship between the anterior attentional system and cortisol regulation. However, these data also illustrate the multifaceted nature of effortful control and the need for care when attempting to understand the neural systems involved in the effortful regulation of behavior.

Attention↗
PubMed1980

Cultural determinants of achievement, aggression, and psychological distress.

We present a cross-cultural exploration of the interrelationships among six concepts: achievement (ie, cultural attainment), aggression, psychological distress, competition, interpersonal intensity (strength of passionate attachments), and social synergy (patterned behavior that simultaneously benefits both individual and society). Of interest is the proposition that levels of achievement, aggression, and psychological distress are partly determined by corresponding levels of competition and interpersonal intensity; however, in the presence of high levels of social synergy, aggression and psychological distress are lowered without affecting the level of achievement. We have tested the implied linear relationships, using blind ratings (of five variables assessed from ethnographic extracts) obtained from ten cross-cultural scholars, and a Social Development Index (from Tatje and Naroll) to indicate achievement. A sample of 58 societies was employed in correlation and multivariate analysis of variance.

Achievement↗
PubMed1997

Affiliative relationships between adult males and immature group members in naturally occurring ringtailed lemurs (Lemur catta).

Affiliative relations between adult males and immature group members were studied in three naturally occurring groups of ringtailed lemurs (Lemur catta) over a 12-month period at Beza-Mahafaly Reserve, southwestern Madagascar. No statistically significant difference was found in rates of affiliative interactions between adult males and older immatures (juveniles and adolescents) over reproductive seasons. However, some of the adult males in two focal groups increased their rates of affiliative behaviors with older immatures during the lactation and subsequent 1993 postmigration periods. Female involvement with infants during lactation season, the increasing independence of juveniles and adolescents, and length of male tenure may be factors contributing to such a pattern. Neither adult males nor immatures were significantly responsible for the initiation and maintenance of proximity in male-immature dyadic interactions. Neither dominance rank nor age-class of the adult male affected their rates of affiliative behavior with immatures. The majority of focal males exhibited an interest in infants and occasionally participated in alloparental care. It is suggested that adult males can benefit from affiliative relations with immatures in terms of opportunities for greater spatial centrality in the group, which can lead to enhanced predator protection and greater opportunities to develop affiliative relationships with females. Immatures can benefit from affiliation with males in relation to enhanced predator detection and protection, alloparental care, and opportunities to develop social skills.

Age Factors↗
PubMed1998

Reflections on prevention in dieting-induced disorders.

OBJECTIVE: The purpose of this article is to reflect on current approaches to the prevention of anorexia nervosa and bulimia nervosa. METHOD: The literature on preventing those disorders was examined within the context of the published literatures concerned with preventive interventions for adolescent drug-taking and alcohol-related behaviors. RESULTS: Our review revealed that those involved in preventing eating disorders maintain the traditional distinction between primary and secondary prevention, although the fruitfulness of that categorization is now uncertain. DISCUSSION: It is argued that interventions for dieting-induced disorders ought to be generic, and target the gamut of transitional risk behaviors among adolescents. Programs for dieting, cigarette smoking, alcohol use, and safe sex within the health and social development curricula in schools must be sustained by comprehensive efforts within the broader context of societal and systemic change.

Adolescent↗
PubMed2003

Predictive, concurrent, prospective and retrospective validity of self-reported delinquency.

BACKGROUND: The self-report method is widely used to measure offending. Previous studies suggest that it is generally valid, but that its validity may be lower for blacks than for whites. AIM To assess the validity of self-reported offending in relation to court referrals, and to investigate how it varies with types of offences, sex and race. METHOD: Annual court and self-report data were collected between ages 11 and 17 for eight offences in the Seattle Social Development Project, which is a prospective longitudinal survey of 808 youths. RESULTS: Self-reports predicted future court referrals. Predictive validity was highest for drug offences, for males and for whites, and lowest for females and Asians. The probability of youths with a court referral reporting offences and arrests was highest for drug offences, for males, for whites and for blacks. Retrospective ages of onset agreed best with prospective ages for drug offences, Asians and whites. More Asians than blacks or whites failed retrospectively to report offences that had been reported prospectively. CONCLUSIONS: The validity of self-reports of offending was high, especially for drug offences, for males and for whites. Contrary to prior research, validity was high for black males. It was lowest for Asian females. Sex and race differences in validity held up after controlling for socioeconomic status. Differential validity probability did not reflect police bias.

Adolescent↗
PubMed2002

Quantification of plasma and egg 4,4'-dinitrocarbanilide (DNC) residues for the efficient development of a nicarbazin-based contraceptive for pest waterfowl.

Urbanization and associated landscaping has increased the abundance of year-round habitat for waterfowl, resulting in vegetation damage, loss of recreational activities, air transportation mishaps and health hazards. As part of a research program to develop socially acceptable techniques for management of pest bird populations, we are evaluating nicarbazin as a contraceptive in pest and surrogate avian species. As reproductive studies with Canada Geese (Branta canadensis) are tedious due to the difficulty of conducting controlled field studies and/or breeding geese in captivity, we evaluated the effects of oral nicarbazin administration on the production and hatchability of chicken eggs. Blood plasma and egg DNC concentrations were correlated to contraceptive efficacy. Subsequent studies are being conducted with geese to determine the diet nicarbazin concentration required to produce the desired blood and plasma DNC concentrations. This approach permits the expeditious evaluation of formulations and dosing regimes by simply monitoring blood DNC concentrations in target species.

Animal Feed↗
PubMed2000

Diffusion of foraging innovations in the guppy.

The way in which novel learned behaviour patterns spread through animal populations remains poorly understood, despite extensive field research and the recognition that such processes play an important role in the behavioural development, social interactions and evolution of many animal species. We conducted a series of controlled diffusions of foraging information in replicate experimental populations of the guppy, Poecilia reticulata. We presented novel foraging tasks over 15 trials to mixed-sex groups, made up of food-deprived and nonfood-deprived adults (experiment 1) or small, young fish and old, large adults (experiment 2). In these diffusions, knowledge of a route to a feeder could spread through the group by subjects learning from others, discovering the route for themselves, or, most likely, by some combination of these social and asocial learning processes. We found a striking sex difference, with novel foraging information spreading at a significantly faster rate through subgroups of females than of males. Females both discovered the goal and learned the route more quickly than males. Food-deprived individuals were faster at completing the tasks over the 15 trials than nonfood-deprived guppies, and there was a significant interaction between sex and size, with a sex difference in adults but not young individuals. There was also an interaction between sex and hunger level, with food deprivation having a stronger effect on male than female performance. We suggest that information may diffuse in a similar nonrandom or 'directed' manner through many natural populations of animals. Copyright 2000 The Association for the Study of Animal Behaviour.

Journal Article↗
PubMed1989

Long-term follow-up of children and juveniles with arachnoid cysts.

In the vast literature on intracranial arachnoid cysts, communication of long-term follow-up is rare. Therefore, we studied the case histories of 60 children and juveniles operated on in our hospital since 1951. The most favorable cases were patients with temporal cysts: 93% recovered fully or with only slight deficits. In other locations (frontal, parietal, occipital, infratentorial), the percentages for a favorable course were lower. The reason cannot be attributed to the operation procedures. Independent of the surgical procedure, there were no postoperative deaths after 1969. Long-term follow-up revealed that, depending on the location of the arachnoid cyst, a high percentage (62%-93% of patients) had normal physical and social development with satisfactory quality of life.

Adolescent↗
PubMed1990

An examination of the differential relationship of marital discord to parents' discipline strategies for boys and girls.

Previous research has tentatively indicated that coercive, ineffective parenting might have a mediating role in the differential impact of marital discord on boys and girls. To further explore this role, we examined the relationship between children's perceptions of marital discord and their evaluations of parental discipline techniques. Ninety-one children aged 8 to 13 years (mean age: 11 years 4 months) were split into high, moderate, and low perceived marital discord on the basis of their responses to the Children's Perceptions Questionnaire (Emery & O'Leary, 1982). The children rated how coercive they believed both mothers and fathers would and should be in three discipline situations. Children with high marital discord indicated that both mothers and fathers would and should use more coercive behavior than did children with low marital discord. The effects of marital discord were stronger for boys than for girls. All children also believed that fathers would and should be more coercive than mothers. Results are discussed in relation to the effects of marital discord on children's social development with regard to sex of the child.

Adolescent↗
PubMed1993

Lesbian, gay, and bisexual youth in community settings: personal challenges and mental health problems.

Studied 194 lesbian, gay, and bisexual youth aged 21 and younger who attended programs in 14 community centers to determine the personal challenges they face due to their sexual orientation and their responses to these stresses. First awareness of sexual orientation typically occurred at age 10, but disclosure to another person did not occur until about age 16. There was much variability in sexual behavior, and many youths reported both same-sex and opposite-sex sexual experiences. Although most had told at least one family member about their sexual orientation, there remained much concern about family reactions. Suicide attempts were acknowledged by 42% of the sample. Attempters significantly differed from nonattempters on several milestones of sexual orientation development, social aspects of sexual orientation, parents' knowledge of sexual orientation, and mental health problems.

Adaptation, Psychological↗
PubMed1996

Cholesterol screening in childhood: results of a 9-year follow-up study in Swiss and Italian children in Switzerland.

Mass screening for blood cholesterol as part of routine preventive health care of children continues to be discussed in several countries. Results of longitudinal studies underline the importance of the predictive value of cholesterol levels assessed during childhood. Some countries have changed their recommendations during the past years to blood cholesterol screening for obese children only or for children of high risk families. In the Kindergarten-study Basel, a follow-up study on somatic, psychic and social development of Swiss and immigrant schoolchildren, cardiovascular risk factors were assessed at the ages of 5, 10 and 14 years. The age-specific levels of total and LDL-cholesterol found in our study were slightly higher and HDL-cholesterol lower than, for example, those found in the Bogalusa Heart Study. For total cholesterol no significant tracking correlations over the 5 and 9 year periods were found. Tracking of LDL- and HDL-cholesterol differed between nationalities and sexes. The total cholesterol/HDL-cholesterol index tracked slightly better. Italian girls showed the best 9-year tracking for HDL-cholesterol (r = 0.56). The differences between this and other studies can only partially be explained by different sampling and laboratory methods. Individual changes in cholesterol levels between the ages of 5 and 14 were marked. Sexual maturation was found to be of minor influence. Body mass index was the most consistent risk factor in our population. Changes of sex or growth hormone levels during puberty, but also changes of nutritional habits or physical activity might influence the individual cholesterol levels. Before recommendations on mass screening of cholesterol in children are made, the different longitudinal patterns of changes in cholesterol levels, and subpopulation-specific changes of nutritional habits and physical activity, should be discussed. The results of the Kindergarten study Basel suggest that attention should be paid to screening for obesity and to health education regarding nutrition and physical activity.

Adolescent↗
PubMed1992

Schizoaffective disorders with and without onset in the puerperium.

The premorbid and sociodemographic features, long-term course and long-term outcome (on average 23.8 resp. 26.8 years after onset of illness) were compared in 30 female schizoaffective patients with onset of their illness during the puerperium and 60 female schizoaffective patients with onset at other times. The majority of premorbid and sociodemographic variables as well as course parameters were similar in the two groups. Most of the few differences (in age at first manifestation, marital state at onset, presence of stable heterosexual relationship before onset, acuteness of onset, presence of life events) are closely connected with the inclusion and exclusion criteria applied for the puerperal disorders (exclusion of patients with preexisting illness or psychiatric symptoms during pregnancy, inclusion only if onset was within 6 weeks of parturition). The puerperal schizoaffective disorders began more frequently with a schizomanic episode and less frequently with a schizodepressive episode than did the non-puerperal schizoaffective disorders, a finding which perhaps reflected the "pathoplastic" role of the puerperium on psychotic disorders. Several significant differences were found regarding the long-term outcome (frequency of persistent alterations, level of global functioning and disability, non-achievement of the expected social development, loss of autarky), confirming earlier findings that puerperal disorders generally have a better outcome than other psychotic disorders.

Adolescent↗