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Results for “MENINGOCELE”

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At least 1,207 records · Page 67Linked to original sources
PubMed1978

So-called hairy polyps or teratoid tumors of the nasopharynx.

Two new cases of hairy polyp of the nasopharynx, one with congenital atresia of the left carotid artery, are added to 111 cases that have already been reported. Unlike trigerminal neoplastic teratomas, the hairy polyps are derived from two germ cells, the ectoderm and mesoderm. They are composed of a conglomeration of disorganized and disorderly tissues that form a sessile to a pedunculated mass that is attached to the nasopharynx. They are strictly developmental anomalies in early embryogenesis with very limited growth potential. We discuss their clinical features, diagnosis, and development. In an evaluation of any nasopharyngeal mass in the newborn, consideration should be given as to whether the mass arises in the nasopharynx or is an extracranial extension of glioma or encephalocele.

Adolescent↗
PubMed1992

The utility of magnetic resonance imaging in the diagnosis of intranasal meningoencephaloceles.

We present three patients in whom the diagnosis of intranasal meningoencephalocele was made by magnetic resonance imaging. The initial clinical evaluation and computed tomographic examinations of these patients failed to distinguish between chronic inflammation and intranasal meningoencephalocele. Although both computed tomography and magnetic resonance imaging are used to distinguish between normal, inflammatory, and neoplastic tissue in the nasal cavity and paranasal sinuses, limitations do exist and these are the focus of our communication. A clear understanding of the efficacy of these radiographic modalities will enhance surgical planning and can preclude severe complications.

Encephalocele↗
PubMed2000

Prenatal sonographic detection of a lipomeningocele as a sacral lesion.

We present a case of a lipomeningocele in a newborn. Prenatal sonography revealed dysraphia and a 3.8 x 4.3 cm, semisolid, echogenic mass that was continuous with the sacral area and bulged posteriorly under the skin. The mass was diagnosed after birth as a lipomeningocele based on the results of MRI. This diagnosis was confirmed histologically.

Adult↗
PubMed1990

Aminopterin-like syndrome sine aminopterin associated with translocation involving chromosomes 5 and 10.

We studied a baby born with physical features suggestive of the aminopterin syndrome, but without exposure of the mother to aminopterin during pregnancy. G-banded chromosomes from peripheral blood lymphocytes had a normal 46,XX pattern. However, in 50 skin fibroblasts there was a normal female karyotype in 5 cells and 45 cells showed an apparently balanced reciprocal translocation involving the long arm of chromosome 5 (band q35) and the long arm of chromosome 10 (band q22). The relation of this mosaicism to the abnormal phenotype is unclear.

Abnormalities, Multiple↗
PubMed1993

Evidence for multi-site closure of the neural tube in humans.

Four separate initiation sites for neural tube (NT) fusion have been demonstrated recently in mice and other experimental animals. We evaluated the question of whether the multisite model vs. the traditional single-site model of NT closure provided the best explanation for neural tube defects (NTDs) in humans. Evidence for segmental vs. continuous NT closure was obtained by review of our recent clinical cases of NTDs and previous medical literature. With the multi-site NT closure model, we find that the majority of NTDs can be explained by failure of fusion of one of the closures or their contiguous neuropores. We hypothesize that: Anencephaly results from failure of closure 2 for meroacranium and closures 2 and 4 for holoacranium. Spina-bifida cystica results from failure of rostral and/or caudal closure 1 fusion. Craniorachischisis results from failure of closures 2, 4, and 1. Closure 3 non-fusion is rare, presenting as a midfacial cleft extending from the upper lip through the frontal area ("facioschisis"). Frontal and parietal cephaloceles occur at the sites of the junctions of the cranial closures 3-2 and 2-4 (the prosencephalic and mesencephalic neuropores). Occipital cephaloceles result from incomplete membrane fusion of closure 4. In humans, the most caudal NT may have a 5th closure site involving L2 to S2. Closure below S2 is by secondary neurulation. Evidence for multi-site NT closure is apparent in clinical cases of NTDs, as well as in previous epidemiological studies, empiric recurrence risk studies, and pathological studies. Genetic variations of NT closures sites occur in mice and are evident in humans, e.g., familial NTDs with Sikh heritage (closure 4 and rostral 1), Meckel-Gruber syndrome (closure 4), and Walker-Warburg syndrome (2-4 neuropore, closure 4). Environmental and teratogenic exposures frequently affect specific closure sites, e.g., folate deficiency (closures 2, 4, and caudal 1) and valproic acid (closure 5 and canalization). Classification of NTDs by closure site is recommended for all studies of NTDs in humans.(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗
PubMed1985

A congenital meningocoele in prehistoric Australia.

This report concerns a congenital meningocoele in a young adult Aboriginal female from north-western New South Wales, Australia. The fact that this individual reached adulthood throws new light on the attitude of these nomadic people towards such conditions. Evidence of this kind may prompt also a re-evaluation by prehistorians and anthropologists of the popularly held belief that all such malformations were automatically eliminated by infanticide. The discovery of this form of pathology helps provide new information not only on past cultural attitudes towards disease, but its frequency and geographical incidence, and adds to our knowledge concerning the range of pathological conditions suffered by prehistoric societies worldwide.

Australia↗
PubMed1996

Surgical management of superficial siderosis following cervical nerve root avulsion.

Neurosensory hearing loss, ataxia, spastic paraparesis, sphincter dysfunction, somatosensory disturbances, and cognitive effects are associated with superficial siderosis of the central nervous system caused by chronic intrathecal bleeding. We describe superficial siderosis that developed more than a decade following traumatic brachial nerve root avulsion. While cerebrospinal fluid analysis indicated chronic intrathecal bleeding, angiography did not localize a specific source. Surgical intervention that included repair of a meningeal diverticulum and venous cauterization resulted in overall reduction, but not complete elimination, of central nervous system bleeding.

Brachial Plexus↗