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Diagnostic imaging of diseases affecting the mandible with the use of computed panoramic radiography.

Computed panoramic radiography was performed on patients with bone cyst, osteomyelitis, gingival cancer, and fibrous dysplasia, respectively, to determine the best imaging procedure for disease processes affecting the mandible. Gradational enhancement images for detection of density changes and frequency enhancement images for detecting changes in the margin and texture were effective in aiding the diagnosis of diseases of the mandible with the use of computed panoramic radiography.

Bone Resorption↗

Diffuse sclerosing osteomyelitis of the mandible: a new concept of its etiology.

Diffuse sclerosing osteomyelitis of the mandible is a disease of unknown etiology. The clinical and radiographic findings suggest an infectious origin, but bacteriologic and histologic findings do not support this concept. Analysis of clinical symptoms, localization of the condition, and posttreatment findings in a group of 27 patients suggest a chronic tendoperiostitis due to muscular overuse as an etiologic factor in diffuse sclerosing osteomyelitis of the mandible. This hypothesis was supported by the initial results of muscle relaxation treatment in 13 of these patients.

Adolescent↗

Hemophilic pseudotumor of the mandible. Report of a case.

Hemophilic pseudotumor of bone is a rarely encountered lesion associated with hemophilia. To date, only eight cases in the mandible have been reported in the literature. A rare case occurring in the mandible of a 2 1/2-year-old child required the fabrication of a customized wound obturator for postoperative wound care after surgical curettage. The literature is reviewed and the obturator described.

Child, Preschool↗

Osteomyelitis of the mandible as a result of sickle cell disease. Report and literature review.

Only five cases of osteomyelitis of the mandible as a result of sickle disease have been published. We report another case, which uniquely affected not only the osseous portion of the mandible, including the condyle, but also the adjacent musculature. Radical resection of the involved hard and soft tissue was necessary to cure the patient. Two possible etiologies are discussed. The first states that the sickle cell crisis caused a tissue anoxia in which this tissue became secondarily infected; the second states that the preexisting infection triggered or augmented the sickling phenomena.

Adult↗

Diffuse sclerosing osteomyelitis (chronic tendoperiostitis) of the mandible. An 11-year follow-up report.

Diffuse sclerosing osteomyelitis of the mandible is a disease that is characterized by a protracted course of recurrent pain, swelling of the cheek, and trismus. The cause of the lesion has been obscure for a long period of time. Recent research, however, pointed out that this disease is likely to be caused by overuse of the jaw musculature (chronic tendoperiostitis) and can be treated accordingly. The protracted course of the disease and the difficulty of treatment with an eventual positive outcome are illustrated by a case report of a 65-year-old man with an 11-year history of diffuse sclerosing osteomyelitis (chronic tendoperiostitis) of the mandible.

Aged↗

Changes in masseter inhibitory reflex responses in patients with diffuse sclerosing osteomyelitis of the mandible.

Masticatory inhibitory mechanisms were studied in 10 patients treated for diffuse sclerosing osteomyelitis of the mandible. Their masseter inhibitory reflex responses were provoked electrically by mental nerve stimulation during maximal clenching of the teeth. The masseter inhibitory reflex was normal in two patients and significantly abnormal in eight patients. The two patients with a normal masseter inhibitory reflex were free of complaints, whereas, of the eight patients with an abnormal masseter inhibitory reflex, two were free of complaints and six had moderate to severe symptoms. In three patients, spasms and involuntary bursts of electromyographic activity were found. The abnormal masseter inhibitory reflex consisted of a loss of early and late components in four patients or a loss of the late component with a normal early one in four patients. These findings seem to support the hypothesis that diffuse sclerosing osteomyelitis of the mandible is a chronic tendoperiostitis caused by muscle overuse. It is suggested that this overuse is caused by central hyperexcitability of trigeminal motoneurons.

Adolescent↗

Central hemangioma of the mandible.

Central hemangioma of the mandible is a relatively rare condition; when it occurs, the clinical and radiographic presentation are often nonspecific. A proper diagnosis can be made with a high level of clinical suspicion, and imaging studies such as angiography can confirm the suspicion that a vascular lesion exists and can contribute valuable information to the preoperative data base. We report three cases of central hemangioma of the mandible demonstrating the variability of signs and symptoms and review the various treatment alternatives in the literature. We suggest that the treatment of choice for this entity is surgery, including reconstruction as necessary.

Adult↗

Is diffuse sclerosing osteomyelitis of the mandible part of the synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome? Analysis of seven cases.

Diffuse sclerosing osteomyelitis of the mandible has been described as a localized disease of unknown origin. We offer evidence that mandibular involvement in the recently described synovitis acne pustulosis hyperostosis osteitis syndrome exactly fits the accepted description for diffuse sclerosing osteomyelitis of the mandible. The clinical, radiologic, and pathologic findings in seven such cases are presented and discussed.

Acne Vulgaris↗

Myxoma of the mandible.

Myxoma is a rare bone tumor of the jaws. The exact aetiology and pathogenesis of this tumor still remains obscure. The tumor is frequently seen in young adults and in the mandible. Enucleation or local curetting have been recommended in the literature as the treatments of choice, although some authors have suggested more radical procedures because of the recurrences. In this paper a case of myxoma of the mandible and a review of the literature is presented.

Child↗

Alternatives in the management of aneurysmal bone cysts of the mandible.

Aneurysmal bone cyst (ABC) is an unusual expansile lesion of bone which may arise within the mandible on rare occasions. This lesion may arise with very few signs or symptoms. Surgical treatment consists of complete excision or curettage. The recurrence rate may be high in lesions which are incompletely excised. Three cases of aneurysmal bone cysts in children will be presented, demonstrating the wide variation of clinical presentation. One case required an extensive mandibular resection, necessitating the first reported microvascular mandible reconstruction for this entity in a pediatric patient.

Adolescent↗

Ewing's sarcoma of mandible.

Ewing's sarcoma is a highly malignant tumour which develops from the medullary tissue of bones. It accounts for four to five per cent of all primary bone tumours (Ackerman et al., 1968; Dahlin, 1978) and usually presents as a solitary lesion in patients below the age of 30 years. It is most commonly situated in a long bone of the upper and lower extremities, pelvis, ribs and vertebrae. We describe the clinico-pathological features and management of a 19 year old male patient who developed Ewing's sarcoma of the mandible, an uncommon site of origin. It is hoped that the improvement in prognosis of this tumour observed in other sites due to aggressive chemotherapy will also pertain for Ewing's sarcoma within the mandible. This case illustrates the difficulties of management at this anatomic site.

Adult↗

Osteomyelitis of the mandible in sickle cell homozygous patients in Nigeria.

Osteomyelitis of the mandible is a very rare complication of sickle cell disease. Three cases of chronic osteomyelitis of the mandible complicating sickle cell disease were seen over a period of 9 years at the University of Benin Dental Hospital, Benin City, Nigeria. A brief review of the current understanding of the pathogenesis of sickle cell disease is given with a suggested non-radical approach to sequestrectomy.

Adolescent↗

Intermaxillary fixation compared to miniplate osteosynthesis in the management of the fractured mandible: an audit.

The hospital records of 30 patients with isolated fractured mandibles treated by intermaxillary fixation (IMF) were compared to 30 patients treated by miniplate osteosynthesis. The treatment variables assessed were the period of hospitalisation, the operating time, the use of intensive care or nurse specialing services, the number of outpatient visits, and the cost of materials. The cost of each facility was calculated from six sources, so that the average cost of each method of treatment could be determined. The results showed that the average cost for managing a fractured mandible with IMF was 1000 pounds if the intensive therapy unit (ITU) was used and 919 pounds if ward specialing services (a single nurse looking after the patient) were used. This compared with an average cost of 794 pounds for miniplate osteosynthesis. The extra cost of the materials if miniplates were used could be discounted by the longer period of hospitalisation, the use of ITU or nurse specialising services, and the greater number of outpatient visits that were required for patients treated with IMF. In addition the use of IMF significantly increased the time patients spent off work.

Absenteeism↗

Ewing's sarcoma of the mandible: a case report.

The authors report the case of an 8-year-old boy with a Ewing's sarcoma localized to the mandible. The therapeutic modalities consisting of induction chemotherapy, surgical removal of the involved portion of the mandible with reconstruction using a parascapular osteo-cutaneous free flap, and maintenance chemotherapy are described. Emphasis is placed on the importance of performing a wide resection and the use of a multidisciplinary team approach in the treatment of these unusual tumours.

Cell Nucleolus↗

Intraosseous leiomyoma of the mandible: report of a case.

A rare case of intraosseous leiomyoma of the mandible is reported. This is the fourth recorded case involving the mandible. The literature is reviewed and the amenability of the lesion to simple local excision is highlighted.

Actins↗

Open-packing method for the severely comminuted fractured mandible due to missile injury.

A new approach is introduced to treat a severely comminuted fractured mandible due to missile injury, whereby denuded bony pieces are re-incorporated into the defect. These are then immobilized by open-packing with iodoform ribbon gauze. The pack is changed regularly every 10-14 days until the cavity is completely obliterated with healthy granulation tissue by which time the mandible shows good consolidation with re-alignment of all displaced bony fragments. The method is simple, safe, does not need an expert surgeon and avoids the need for a future bone graft. Iodoform packs were used in different sites of the facial skeleton and none of our patients showed signs of sensitivity to iodoform or to iodine toxicity.

Adult↗

Fluoride in mandibles and antlers of roe and red deer from different areas of England and Scotland.

Fluoride concentrations were measured in mandibles of 112 male roe deer (Capreolus capreolus) aged 1-6 years, from 5 localities in England and Scotland; also in bone from sections cut in series from orbit to antler-top of 10 other roe deer. Fluoride concentrations in mandibles were mostly within values expected from unpolluted areas, but approached those expected from moderately polluted areas at the upper end of their range, which extended from 43 to 901 microg g(-1). There were large variations in mandibular fluoride content between individual animals within each age group, and an upward trend of fluoride content with increasing age. There were also considerable differences in mandibular fluoride content between localities. No gradient in fluoride concentration was evident between the upper part of the skull and various points along the antler in 9 roe deer. A tenth animal showed an increase of 65% in fluoride concentration between the skull and the top of the antler, with exceptionally high values ranging from 1220 to 2010 micro g(-1). For 3 red deer (Cervus elaphus), no significant differences in fluoride concentrations were found between trabecular and cortical antler bone.

Journal Article↗

Metastatic adenocarcinoma from the colon to the mandible.

Published reports of metastatic adenocarcinoma from the colon or rectum to the mandible are extremely rare. Only eight cases had been reported from 1884 to the time this article was written. A case is presented where a metastatic lesion was found to be histologically similar to the known primary tumor in the cecum. The patient first noted dental pain, isolated to his mandibular left second bicuspid, 10 months after a primary tumor was diagnosed. Subsequently, the tooth was extracted, and it was only after the extraction site failed to heal that a biopsy was performed which confirmed a metastatic lesion. Retrospective study of the preextraction radiograph confirmed the presence of a suspicious area in the osseous structure of the mandible at the time of extraction. It must be emphasized that in patients with a positive history of malignancy, metastatic disease must be considered in the differential diagnosis of oral and dental symptoms, and that need for biopsy should be considered with all surgical procedures, including simple extractions.

Adenocarcinoma↗