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A case of recurrent cementifying fibroma of the maxilla has been presented. When the lesion was excised in 1948, it was reportedly well delineated from surrounding bone. There was no delineation of the tumor from the surrounding bone at the time of the operation in 1972.
A 3 1/2-year-old girl presented with a lytic lesion in the diametaphyseal region of the right fibula. In addition to plain roentgenography, radiological evaluation consisted of bone scintigraphy and computed tomography. The radiological features suggested a benign lesion. Pathological examination revealed a chondromyxoid fibroma.
Study of physicochemical properties of lipids in the donor blood and blood of patients with fibroma and uterus cancer showed that the progress of pathological processes may lead to the rise of peroxidation and peroxide accumulation, phospholipid balance disturbance, that causes drastic changes in biomembranes. As a result of this the disturbance of the structure and change in the functional activity of the membranes take place.
Chondromyxoid fibroma is a relatively rare benign bone tumor whose histologic and radiologic patterns are well known. In this article, we describe a 16-year-old boy with such a tumor in his left tibia. Scintigraphically, this tumor is represented by a "doughnut sign". This aspect, though not pathognomonic, has been reported sporadically in a few diseases: osteoporosis circumscripta cranii, angioblastic meningioma, cranial coccidioidomycosis, and aseptic necrosis of frontal bone. Because of their sites, it is easy to reject these diagnoses in our patient. The most pertinent differential diagnosis with regard to the clinical, radiological, and scintigraphic aspects in the patient is that of a giant cell tumor.
The authors report the exceptionally rare case of a huge myofibroma of the round ligament. The localization of the myoma was very unusual. It developed from the inguinal insertion of the round ligament; and the fibroma had grown in the abdominal wall between muscle and the peritoneum. Consequently the mass was both abdominal and extra-peritoneal. To our knowledge, such an association has never before been described. In the case described here, the mass was asymptomatic and the patient presented because of her increasing abdominal size. Examination revealed an abdominal mass that almost reached the umbilicus and resembled a four months pregnancy. Ultrasonography showed that the uterus was normal. The mass was a 15 cm by 15 cm tumour of heterogenous structure. As the ovaries were not visualized it was impossible to decide whether the tumour was ovarian, intestinal or peritoneal. Laparotomy was performed with a preliminary diagnosis of a solid ovarian tumour. It was then possible to localize the mass accurately and to define it. Histological examination showed that it was a leiomyoma. Tumours of the round ligament are very uncommon. Among these tumours leiomyomas are the most frequent. Endometriotic tumours come next. Various very rare tumours can also be found. Leiomyoma of the round ligament may arise from each portion of the ligament: abdominal, inguinal or Labium Majus. But both abdominal and extra-peritoneal development from the inguinal insertion of the ligament is rare. They are usually single, and unilateral, and are found by chance.(ABSTRACT TRUNCATED AT 250 WORDS)
An unusual case of ameloblastic fibroma involving two supernumerary teeth in the anterior part of maxilla has been presented here. The radiographic picture mimics a dentigerous cyst where there is a gross migration of one of the involved super-numerary tooth. After the histopathological diagnosis, the lesion was treated with enucleation and curettage.
The authors report 6 cases of fibrous dysplasia (F.D.) of the base of the skull and review the literature. They confirm the impossibility of histological differentiation between ossifying fibroma and monostic dysplasia with cranio-facial sites. They stress the value of CAT scan in the assessment of spread and that of dynamic isotope scan in the differential diagnosis with plaque-shaped hyperostotic meningioma, in the diagnosis of polyostotic forms and in postoperative surveillance. They stress the risk of visual sensorial impairment: visual by stenosis of the optic canals and auditory by stenosis of the E.A.M. Operative indications are influenced by this risk, thereby explaining the need for prolonged surveillance.
The authors report a rare case of complication of aseptic necrosis of a fibroma. In early pregnancy: intraperitoneal rupture resulting in an obstructive syndrome secondary agglutination of small bowel loops. They attempt to explain the mechanism of this complication and stress the fact that surgical treatment is exceptional in complications of necrosis, and a medical treatment is usually sufficient, in most cases.
The clinical and radiological features in a case of a juvenile ossifying fibroma of the skull were studied with CT and MRI. The combination of both imaging modalities allows a precise prediction of tumor components and extension.
Rabbit fibroma virus injected into the dermis of adult rabbit skin evokes an inflammatory, then granulomatous and finally proliferative or tumoral response. About 1 week after injection, the grossly visible nodular lesion reaches its maximum size and regresses, becoming hemorrhagic and necrotic. Unlike vacciiia, the morphogenesis of the RFV has not been validated satisfactorily. The present study shows that RFV-infected cells contain all the evolutive forms that have been identified during the course of vaccinia virus replication. In addition, long, twisting, intracytoplasmic lamellated inclusions were found in infected cells. These lamellae were composed of linear arrays of elongated, electron-dense fibers. When the inclusion was sectioned in a plane perpendicular to the fiber, the latter was found to be covered by projections approximately 160 A long, spaced at intervals of approximately 80-90 A; when sectioned tangentially, the lamellae appeared to be composed of tubules. Evidence is presented showing the similarities between the subunit of the lamellated inclusion and the virus membrane. It seems likely, therefore, that the viral membrane is covered by closely packed tubules approximately 160 A long. The lambellar inclusion is thought to represent abnormal synthesis or excessive formation of viral membranes. In addition to lamellae, which probably indicate some defect in virogenesis, some infected cells contained viral membranes partially or completely encircling the host's cell constituents, or fragments of viral membrane instead of viral matrix. Furthermore, structures resembling virus nucleoid were lying free in the viral or cytoplasmic matrix. The course of viral morphogenesis was correlated with viral multiplication and the kinetics of interferon production at the site of viral inoculation in the rabbit skin.
This study is based on 170 cases of histiocytic fibroma of bone. This is a metaphyseal hamartoma composed of histio-fibroblasts; it is completely benign, and affects children and adolescents. Because of their benign nature and characteristic radiographic appearance, which is almost always diagnostic, these tumours do not require surgery, except in rare forms that give rise to symptoms, or in which tthe radiographic appearances are atypical and clarification of the diagnosis is called for.
A new case of chondromyxoid fibroma of the jaw arising in a 16-year-old white girl is presented. It is possible that unrepresentative biopsy specimens of this condition could be misdiagnosed as myxofibroma, chondrosarcoma, or mesenchymal chondrosarcoma.
An unusual lesion developed in the trapezoid of a 25-year-old man. The tumor had histologic features most consistent with a diagnosis of chondromyxoid fibroma and had not recurred four years after curettage and bone grafting.
Recurrence of an aneurysmal cyst and cementifying fibroma in a 13 year old adolescent required treatment by mandibular resection. Published data on combined aneurysmal cysts and other lesions are reviewed and a new entity, the desmoosteoblastoma of the psammomatous type, discussed.
The features of two cases of central odontogenic fibroma are presented and the literature is reviewed. Controversial issues surrounding this neoplasm are discussed. The cases presented here include the oldest reported patient with this neoplasm and the first instance of its occurrence at a maxillary site. Treatment and follow-up information emphasize the benign nature and slow growth of these lesions.
The parameters of cell-mediated immune responses of adult rabbits infected with Shope fibroma virus (SFV) were characterized by measurement of the size of local draining nodes, number of cells per lymph node, mitogen responses of lymphocytes, and kinetics of virus-specific cell-mediated lymphocytotoxicity (CML). In addition, the cytolytic effector population was characterized. After intradermal injections, tumors appeared within 3-4 days, reached maximum size in 10-12 days, and then regressed completely with 24 days. The size of local popliteal lymph nodes, in particular the diffuse cortex (paracortex), and the number of cells per node increased during tumor growth but then declined as the tumor regressed. Maximum specific CML to SFV-infected kidney cell monolayers (RK-13) occurred 10 days after inoculation of SFV and correlated with the initiation of tumor regression. Adult cytotoxic lymphocytes passed through nylon wool, and most of their activity was removed by treatment with antithymocyte globulin plus complement. Cytotoxic T-cells from SFV tumor-bearing rabbits killed only targets infected with SFV and not targets uninfected or infected with vaccinia virus. Therefore, T-cell-mediated virus-specific CML appeared as a major immune effector mechanism that correlated with tumor regression. However, antibody-dependent cell-mediated and NK cytotoxicity were also demonstrable. The presence of different cell-mediated cytotoxic mechanisms suggested a heterogeneity of effector mechanism.
A resected case of chondromyxoid fibroma of the right fibula in a 31-year-old male is presented. The histology was composed of characteristic lobular features of this tumor with abundant cartilaginous matrix. The ultrastructural study exhibited stellate, ovoid or elongated tumor cells with features of cartilage cells and abundant loose matrix with many fine filamentous structures. The nuclei were often of peculiarly indented contour and revealed thick fibrous lamina. The villous cell processes and intracytoplasmic fine filaments were prominent. No cells suggesting a fibroblast were recognized in this study. From the light microscopical and ultrastructural findings of this case, it is supported that this tumor might be derived from adult cartilage cells most likely related to the epiphyseal cartilage rather than fibroblasts.
Chondromyxoid fibroma involved the spinous process of L2. To our knowledge, this is the first reported occurrence in the lumbar spine.