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Governments' perceptions and policies of population redistribution in East and South East Asia.

"This paper is based on the results of the Third Inquiry among Governments on Population and Development carried out in 1977 by the UN Secretariat. It reports on perceptions and policies concerning international migrations, spatial distribution of the national population, internal migration and settlement patterns in fourteen South East and East Asian countries. "It appears that nearly all countries under consideration were concerned with the spatial distribution of population both as a factor related to problems caused by excessive natural increase and as a problem on its own right. The majority of countries were prepared to pursue policies affecting basic trends in internal migration. Most governments declared their willingness to alter patterns of rural or both rural and urban settlement. Only two countries were interested in increasing emigration; the remaining ones were satisfied with the existing levels of international migration."

Asia↗

Health status, health problems and practices among refugees from the Middle East, Eastern Europe and Southeast Asia.

Recent refugees from Poland, Romania, Iraq, and Vietnam were extensively interviewed to assess their health, health care utilization, and health services use barriers. 277 recent arrivals from these countries and 63 previously arrived Laotians comprised the 1983-1985 sample from the Detroit metropolitan area. Results from a 195-item bilingual questionnaire indicated good overall health and little evidence of serious physical health symptoms. Dental health was the area of greatest reported need. Prenatal care and mental health services were additional areas of need noted by researchers. Barriers to health service utilization were primarily language related. There were major differences in both health problems and health service utilization among the 4 groups surveyed.

Americas↗

Detection of HIV type 1 env subtypes A, B, C, and E in Asia using dried blood spots: a new surveillance tool for molecular epidemiology.

Global surveillance of HIV-1 subtypes for genetic characterization is hampered by the biohazard of processing and the difficulties of shipping whole blood or cells from many developing country regions. We developed a technique for the direct automated sequencing of viral DNA from dried blood spot (DBS) specimens collected on absorbent paper, which can be mailed unrefrigerated in sturdy paper envelopes with low biohazard risk. DBS were collected nonrandomly from HIV-1-infected, mostly asymptomatic, patients in five Asian countries in 1991, and shipped via airmail or hand carried without refrigeration to Bangkok, and then transshipped to North America for processing. After more than 2 years of storage, including 6 months at ambient temperatures, proviral DNA in the DBS was amplified by nested PCR, and a 389-nucleotide segment of the C2-V3 env gene region was sequenced, from which 287 base pairs were aligned and subtyped by phylogenetic analysis with neighbor-joining and other methods. From southern India, there were 25 infections with subtype C and 2 with subtype A. From Myanmar (Burma), we identified the first subtype E infection, as well as six subtype BB, a distinct cluster within subtype B that was first discovered in Thailand and that has now appeared in China, Malaysia, and Japan. From southwest China, one BB was identified, while a "classical" B typical of North American and European strains was found in Indonesia. From Thailand, five DBS of ambiguous serotype were identified as three B, one BB, and one E. A blinded control serotype E specimen was correctly identified, but a serotype BB control was not tested. Most HIV-1 in southern India appears to be env subtype C, with rare A, as others have reported in western and northern India. The subtypes BB and E in Myanmar, and the BB in China, suggest epidemiological linkage with these subtypes in neighboring Thailand. DBS are a practical, economical technique for conducting large-scale molecular epidemiological surveillance to track the global distribution and spread of HIV-1 variants.

China↗