Cervical cancer in Pacific Island Polynesians.
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Studies were performed on 13 Polynesian children who suffered from recurrent respiratory disease characterised by cough, wheeze, tachypnoea and radiological opacities. Only one was substantially underweight. Most had iron deficiency anaemia. Serum IgG levels were high with a less definite trend to raised IgA and IgM levels. Precipitating antibodies to cow's milk protein were found in 6 out of 10 children tested who were currently on cow's milk feeds. The proportion of rosette-forming lymphocytes was reduced in 8 of the 12 tested. The Mantoux test using using 10 TU of PPD was negative in 7 out of 10 children who had had BCG in the newborn period. The likelihood of cow's milk contributing to the respiratory disease in these children is discussed.
The prevalence of enamel crazing was determined from the maxillary incisors and canines of 1,109 Tongan residents aged 5-20 years, 1,417 Cook Island residents aged 6-20 years, 520 French Polynesian residents aged 10-15 years, and 92 New Zealand-born and -resident Polynesians aged 11-18 years. Crazing occurred in 22 percent of Tongans, 7 percent of Cook Islanders, but not in French Polynesians or New Zealand-born Polynesians. Cracks become clinically apparent at about 8 years of age; were more common in males than females; and became more common with increasing age. The central incisors were the most commonly affected of the maxillary anterior teeth. Cross-sections of teeth with crazing viewed by light and scanning electron microscopy appeared similar to other stained cracks. The indications are that crazing is a post-eruptive change caused by trauma from local environmental factors resulting in stress fractures. The significance of crazing on enamel structure and strength is unknown, but it is probably minor without long-term disadvantages. The prevalence of crazing may prove useful in anthropology as an indicator of the use of teeth as tools and in assessing the "modernisation" of a population.
The normal values for glucose, urea, uric acid and creatinine in serum have been determined in a selected Polynesian population. The results are similar for obese or non-obese subjects as well as for the people living in Papeete. A comparison between these data and the French standard values reveals significant differences in regard to glucose, urea and uric acid.
In a sample of Maoris, the association between a five year incidence of coronary heart disease (CHD) and standard risk factors is examined. Prediction of new cases of CHD is attempted, and systolic blood pressure is found to be the most important predictor in both males and females. Approximately half the new cases are not predicted by the best sets of discriminatory variables.
A review was undertaken of all cases of tuberculous meningitis seen in Wellington since 1962. It showed, in conjunction with an earlier study, a steady decline in the incidence of the disease since 1940. There was a relatively high incidence in Maori and Pacific Island Polynesians. Good outcome was seen in 17/28 (61%). Poor recovery was associated with delayed treatment, confusion or stupor at presentation, and male sex. The diagnosis is not excluded by a normal peripheral white count, ESR, chest x-ray or cerebrospinal fluid.
An anthropometric study was conducted on a sample of preschool children from Mangaia, Cook Islands, and a comparison made with similar measurements made on Caucasian children aged two and four years. At two years there were no differences in height, weight, or fatness as measured by skinfold thicknesses between the populations. By four years, the Mangaian children were shorter, lighter and fatter. It is proposed that this disparity in somatic growth is a result of subtle nutritional deficits in the Mangaian children.
Eosinophilic meningitis is due to infestation of the nervous system by the larvae of Angiostrongylus cantonensis. The infection is from infected prawns and slugs. In a study of 54 patients from Tahiti the leading symptoms were headaches, neck stiffness, limb pains and sometimes a facial palsy. The diagnosis is made by examination of the CSF when the leucocytes are usually over 100/mm3 and over half are eosinophilic cells. The blood eosinophil count is often raised, above 400/mm3. The disease is self-limiting and there is no known specific treatment.
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The purpose of this study is to establish a baseline of information about pre-school Polynesian children hospitalised with wheezing attacks. During a one year study period at Wellington Hospital, 19 percent of the acute paediatric admissions under five years were Polynesians with wheezing respiratory disease. Seventy percent of these admissions were in children under 18 months of age, and 38 percent of the children were readmitted during the year. These and other variables are compared to European children hospitalised with wheezing. We conclude that young Polynesian children in New Zealand are especially prone to a different pattern of asthma from European children.
Tokelau children have been examined for scabies infestation in three groups--those living in their home atolls--those living in New Zealand in 1972-73, and those living in New Zealand in 1975. There was less infestation in Tokelau than in New Zealand. In 1975 the rate of infestation in New Zealand had increased since 1972. The manifestation of the mite in children in New Zealand varied from the classical descriptions, in that the mite itself, and its burrows, were seldom found, and the skin lesions were more often seen on the body than on the wrists and hands. A treatment regime which was found satisfactory is described. It was found essential to treat the entire family at the same time.
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One hundred fifty Polynesians from five different island groups (Samoans, Maoris, Niueans, Cook Islanders, and Tongans) were surveyed for the presence of an Asian-specific length mutation of mitochondrial (mt) DNA by using enzymatic amplification with thermostable Taq DNA polymerase. Ninety-three percent of Polynesians exhibited this 9-bp deletion, including 100% of Samoans, Maoris, and Niueans. The same deletion was also found in 8% of Tolais from New Britain and in 14% of coastal New Guineans. A deletion frequency of 82% in Fijians confirmed their ethnic affinity to Polynesians. In contrast, the deletion was absent in 30 New Guinea highlanders and 31 Australian aborigines, the only exception being an aborigine who also had the Southeast Asian triplicated zeta-globin gene rearrangement in his nuclear DNA. These data support the theories claiming that an independent group of pre-Polynesian ancestors who colonized into the Pacific were ultimately derived from east Asia.
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Asian Pacific Americans are one of the smallest but fastest growing minority groups in the United States. Between 1970 and 1980, this population increased 142 percent, from 1.5 million to 3.7 million. This dramatic growth is due largely to a change in U.S. immigration policies in the mid-1960s and the continuous influx of refugees from Southeast Asia since 1975. Despite such sharp increase, Asian Pacific Americans remain one of the most poorly understood minorities, and their health care needs have received relatively little attention. Health policy makers, planners, and service providers need to have a better understanding of the population characteristics of Asian Pacific Americans in order to address their needs properly. Asian Pacific Americans are largely recent immigrants and refugees. They are extremely heterogeneous and bipolar in socioeconomic status and health indices. Because of their small numbers until the last two decades, many health workers have had little exposure to this minority, their culture, and health problems. Health workers need to be sensitive to the ethnocultural barriers that confront recent arrivals; be aware of the genetic disorders, infectious diseases, and mental health problems common in this population; and realize that anatomical and physiological differences may require attention in certain surgical procedures and medical management. Neglecting the health care needs of Asian Pacific Americans is not simply a violation of the principle of equality for all, but also an imprudent act that increases the mortalities and morbidities and health care costs of the nation.