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At least 1,189 records · Page 66Linked to original sources
PubMed2006

Persistent infection in a dairy herd with an unusual genotype of bovine Cryptosporidium parvum.

On two occasions, we identified Cryptosporidium parvum with an unusual banding pattern after restriction enzyme digestion of Cryptosporidium oocyst wall protein PCR fragments. The samples originated from a single farm with calf diarrhoea. The Cryptosporidium oocyst wall protein PCR fragment sequence revealed a point mutation in one of the recognition sites for RsaI. Our subgenotyping showed that samples from both samplings shared the same MS1 and GP15 alleles. Analysis of the TP14 microsatellite was less sensitive, and results were only obtained from two samples. Both had the same allele. This is, to our knowledge, the first description of a C. parvum with this Cryptosporidium oocyst wall protein genotype. More importantly, the genotype seems to be stable over time since we could detect it again among newborn animals almost 1 year after it was first identified.

Animals↗
PubMed1975

In vivo behavior of a Sindbis virus mutant isolated from persistently infected Aedes aegypti cell cultures.

A mutant of the Sindbis virus SV-S was found to interfere with the regular course of infection by the wild strain of the virus SV-W in A. aegypti mosquitoes and in suckling mice. In mosquitoes, this result was manifested by a reduced titer of SV-W in the presence of SV-S and by a failure of the mosquitoes to transmit SV-W. In the brains of suckling mice, in the presence of SV-S, the growth of sc inoculated SV-W was suppressed, and as a result, the usually lethal course of infection by this virus was converted into a nonlethal one.

Aedes↗