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At least 1,189 records · Page 66Linked to original sources
PubMed1980

Radionuclide bone image in growing and stable bone island.

A normal radionuclide bone image can facilitate distinction between a bone island and significant pathologic processes, especially an osteoblastic metastasis. This distinction becomes more crucial when growth is detected in an isolated sclerotic bone lesion or if a relatively large sclerotic lesion is detected de novo in patients with a known neoplasm. This report presents three patients with isolated bone islands: two with interval growth, the other with a relatively large stable lesion; all showing a normal radionuclide bone image.

Acetabulum↗
PubMed1981

Aspects of atypical degenerative lesions of vertebrae.

Over the last 20 years, several authors have reported aspects of degenerative disease of the vertebral column with irregularity and sclerosis of the margins of the vertebral bodies [2, 4, 7-9, 13, 15, 17]. Twenty cases of such atypical degenerative vertebral lesions have been studied over a two year period and their radiological characteristics have been compared with vertebral lesions of infective origin and in the rheumatoid disorders.

Adult↗
PubMed1984

Osteopoikilosis: a radiological and pathological study.

Anatomico-pathological and radiological studies of osteopoikilosis were performed in two cases, one involving a femoral head, excised after a fracture of a femoral neck, in an elderly man and the other following biopsy of an iliac crest in a young woman. In both patients wide-spread radiological evidence of the disorder was present as an incidental finding. The radiological appearance of rounded and linear densities corresponded to old and inactive remodelling of spongy trabeculae in epiphyseal and metaphyseal locations. The distribution and appearance of these osteopoikilotic densities suggested them to have been related intimately to mechanical strain on spongy bone trabeculae. The diffuse nature of the lesions, their hereditary character, and their possible association with abnormalities of the skin suggest the existence of a particular terrain in which general metabolic conditions of connective tissue may interact with mechanical stresses in bone. Careful analysis of the findings in osteopoikilosis is desirable in order to provide data concerning the physiopathology of the skeleton and to permit more definitive interpretation of localised areas of bone condensation, including those observed not only in solitary bone islands and such conditions as osteopathia striata, but also those associated with infections and tumours.

Adult↗
PubMed1985

Sclerotic changes of the manubrium sterni.

Six females with nearly identical sclerotic and hyperostotic changes of the manubrium sterni are reported. Malignancies, bacterial inflammatory processes, and Paget disease, which were first suspected, could be excluded. The youngest patients also had sclerotic changes of other bones, including the lumbar spine, the pubic bone, and the clavicle, and may be classified as having "chronic recurrent multifocal osteomyelitis" (CRMO). The two oldest patients had ossification of the costoclavicular ligament(s) and may be classified as having "inter-sterno-costo-clavicular ossification" (ISCCO). One had only hyperostotic and sclerotic changes as seen in "sterno-costo-clavicular hyperostosis" (SCCH). The pathogenesis of these uncommon diseases is unknown, but they are all frequently associated with pustulosis palmo-plantaris and have similar clinical courses and laboratory abnormalities. None of the present patients had HLA-B27. The similarity of the radiological abnormalities of the manubrium sterni suggests that the diseases themselves may be similar, but with different courses depending on age, CRMO being present in children and young adults and ISCCO or SCCH in older adults.

Adult↗
PubMed1985

Osteopathia striata with cranial sclerosis affecting three family members.

Skeletal surveys were performed on a 38-year-old Japanese mother, her son and daughter. The radiographs of both children showed characteristic features of osteopathia striata. However, in the mother, the skull, mandible, and lower extremities were homogeneously sclerotic with no evidence of a striated pattern of sclerosis in her skeleton. Additional features of striated sclerosis of the mandible in patients with osteopathia striata are discussed.

Adult↗
PubMed1988

Osteosclerotic myeloma variants.

We describe three patients with sclerotic multiple myeloma. One patient had diffuse bone sclerosis, one had mixed sclerotic and lytic lesions, and the third had POEMS syndrome. The radiological, clinical, and etiological features of sclerotic myeloma variants are discussed.

Adult↗
PubMed1989

Inflammatory metachronous hyperostosis of the clavicle and femur in children. Report of two cases, one with long-term follow-up.

Two preteenage girls developed painful swelling of the left clavicle. This was followed by painful swelling of the femur, 7 months later in one girl and 8 years later in the other. Radiographic studies showed a predominantly sclerotic process in one patient and destruction associated with cortical thickening in the other. The patients received analgesic medications only, followed by gradual healing with cortical and medullary sclerosis. Long-term follow-up suggests that the condition is self-limited and that, with or without treatment, the bones eventually return to normal. Although the etiology of the lesions remains unknown, the radiographic features suggest an inflammatory reaction.

Biopsy↗
PubMed1982

Computed tomography in the evaluation of 41 cases of Ewing's sarcoma.

Computed tomography (CT) has already proved extremely effective both in cerebral and abdominal pathology. Several recent publications describing first heterogeneous series [1, 2, 7, 11-17], then studies of a single type of lesion [3-6, 8] have illustrated its usefulness in the study of bone lesions. This report deals with 41 cases of Ewing's sarcoma studied by CT at the Institut Gustave Roussy from October 1977 to July 1981, and tries to show both the limitations and indications of this technique for the diagnosis, treatment, and follow-up of Ewing's sarcoma as well as in the diagnosis of any eventual recurrence.

Adolescent↗
PubMed1980

Long-term results after transfixation of an osteochondritis dissecans fragment to the femoral condyle using autologous bone transplants in adolescent and adult patients.

A review is reported covering 16 adolescent and 15 adult patients treated for osteochondritis dissecans of the femoral condyles by reconstruction of the articular surface and transfixation of the fragment in situ using autologous bone transplants and followed up for a period of up to 18 years. Sixty percent of the patients were totally symptom-free, whereas in others the clinical symptoms had consistently decreased. A radiologically estimated total remodelling of the condylar surface with union of fragment to the osseous bed was seen in 90%. The reduction of the fragment was incorrect in 16% of the cases. Resorption of the distal ends of cortical bone transplants in the articular surface of the condyle was total in 87%. No immobilization or removal of bone transplants was needed after surgery and all patients later on returned to their previous work.

Adolescent↗
PubMed1976

[Kienböck's disease. Follow-up studies and therapeutic considerations (author's transl)].

This paper presents a follow-up of patients with Kienböck's disease up to 30 years after their first symptoms. Only the shortening of the radius and the grafting of the lunate with cancellous bone offers some kind of basic therapy. The intercarpal arthrodesis, the arthrodesis of the wrist and the operation named after Steinhäuser should only be considered in cases with severe deformation and disabling pain.

Adult↗
PubMed1975

Relationship between morphologic features and hardness of the subchondral bone of the medial tibial condyle in the normal state and in osteoarthritis and rheumatoid arthritis.

In osteoarthritis and rheumatoid arthritis the hardness of the subchondral bone of the medial tibial plateau is lower than in normals. In order to further analyse this study of the morphologic characteristics in bone from the mentioned region was carried out in 22 normals, 14 osteoarthritis and 12 rheumatoid arthritis. Specimens from these groups were subjected to a radiologic assay, a light microscopic investigation and an evaluation of the occurrence of intraosseous lipids. The normals showed a remarkable integrity of the subchondral trabecular network with advancing age only with slight osteoporosis and occasional sclerosis. In osteoarthritis there were osteoporosis, osteolysis, sclerosis and osteophytes all in good correlation to the grade of osteoarthritis present. In rheumatoid arthritis there were areas of rarefaction, fractures of the trabeculae, sclerosis and invasion of granulation tissue. The radiologic appearance corresponded well with the morphologic observation. No abnormal presence of lipids was encountered. This investigation supports the concept that the hardness of the subchondral bone of the medial tibial plateau much depends on the morphologic structure of the bone.

Adult↗