ZPEP: an interactive protein sequence analysis program designed for microcomputers.
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This investigation looked at the vocabulary learning and use, and social and communication growth of 8 severely handicapped toddlers under two different language conditions. A computer-based approach was compared to traditional intervention techniques. Treatment conditions were administered in randomized order by two graduate student clinicians. Communication growth was assessed by using a standard set of measures administered before the intervention, at midpoint between the two treatment conditions, and at the end. The results from this study indicated that the subjects made notable progress regardless of the treatment condition received.
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An IBM Personal Computer was used to collect digitally fetal heart rate and uterine contraction data from an electronic fetal monitor. Patient history, physical examination, and pertinent clinical data were also stored electronically. The information was reviewed in an educational format including prospective clinical assessment and patient management. In addition, questions, graded responses and text discussion with references were presented during prospective patient management.
This program provides the nonprogrammer a tool to develop easily modified computer assisted tutorials, tests, and simulations with a word processor. In addition, by using the branching and query features of this program, one can easily develop text files that provide rapid access to information related to patient care such as neonatal formularies and patient care algorithms.
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Recent disasters have focused attention on performance problems due to the use of alcohol and controlled substances in the workplace. Environmental stressors such as thermal extremes, mixed gases, noise, motion, and vibration also have adverse effects on human performance and operator efficiency. However, the lack of a standardized, sensitive, human performance assessment battery has probably delayed the systematic study of the deleterious effects of various toxic chemicals and drugs at home and in the workplace. The collective goal of the research reported here is the development of a menu of tests embedded in a coherent package of hardware and software that may be useful in repeated-measures studies of a broad range of agents that can degrade human performance. A menu of 40 tests from the Automated Performance Test System (APTS) is described, and the series of interlocking studies supporting its development is reviewed. The APTS tests, which run on several versions of laptop portables and desktop personal computers, have been shown to be stable, reliable, and factorially rich, and to have predictive validities with holistic measures of intelligence and simulator performances. In addition, sensitivity studies have been conducted in which performance changes due to stressors, agents, and treatments were demonstrated. We believe that tests like those described here have prospective use as an adjunct to urine testing for the screening for performance loss of individuals who are granted access to workplaces and stations that impact public safety.
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The Austin (or Milner) Maze consists of a 10 x 10 array of electrical contacts through which the subject must discover a hidden pathway by touching successive points in the matrix. Trials needed to reach 3 consecutive errorless performances, errors committed, and time taken to reach this criterion are commonly regarded as indicators of frontal lobe function. This study evaluated the equivalence of a computer-based version of this task. Thirty-two male computer science students completed both forms of the maze in counterbalanced order, separated by an interval of 4 weeks. In a 2-year follow-up, 25 remaining subjects completed the tasks in reverse order, again separated by a 4-week interval. Correlational data and analysis of variance supported the proposition that the computer-based version could act as a substitute for the more tediously administered traditional form. Although the sample characteristics may limit the generalizability of this conclusion, the application and development of the software by independent investigators may facilitate its clinical application and allow a more efficient resolution of relevant theoretical issues.
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Some methods proposed for evaluation of predictable long-term exposure by statistical treatment of workshift exposure values are considered. Predictable long-term exposure is a useful parameter for risk assessment procedures, as it allows the evaluation of workplace hazards by taking into account interday variability of exposure to air contaminants. Statistical calculations required for evaluating predictable long-term exposure may be performed easily by hand-held programmable calculators. The programs reported here are for use with a Texas Instruments TI-59 hand-held programmable calculator equipped with a PC-100 C thermal printer. They are designed for users inexperienced in programming, since an interactive approach has been adopted that helps communication between user and computer.
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