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[Total cholesterol and high-density lipoprotein cholesterol in sensorineural deafness].

In order to verify an assumed hypothesis of a correlation between sensorial hearing loss and arteriosclerosis type injuries, these parameters were studied: total cholesterol and cholesterol associated to high density lipoproteins in order to evaluate the risk of developing coronary heart disease in patients with cochleopathy as compared to control patients. It proved impossible to point out any significant difference between results obtained in the two groups for any of the analytical parameters considered.

Adult↗

[Facial paralysis during progressive chronic otitis. Reflections apropos of 32 cases].

The authors report their experience of 32 cases of facial paralysis occurring during progressive chronic otitis. Twenty were pre-operative. The conclusions which may be drawn are as follows: 1) It occurs in general in cases of severe chronic otitis with large destructive cholesteatomatous and osteitic lesions. 2) Surgery is often difficult, long full of unexpected findings and risks. 3) The development of facial paralysis in a case of progressive chronic otitis is an indication for immediate surgery, on the same basis as a fistula of the H.S.C.C., which is, in fact, oftan present in association. 4) The lesions encountered are much more extensive at the time of secondary (11) rather than at primary surgery (9). 5) The extent of the lesions (13 cases of fistula or laybrinthine destruction) and auditory impairment (16 cophoses or sub-cophoses) are such that tympanoplasty is useless. The authors report their long term results: 13 cases of complete recovery, 4 nil, 3 partial (2 as a result of a superficial cervical plexus graft). They raise the problem of the management when a markedly contused nerve is discovered: simple liberation with incision of its sheath or immediate graft? The other twelve were postoperative. Five were cases operated upon by the autor. There was 100% recovery in all cases, but one patient, in whom the nerve followed an atypical course, required decompression surgery. In the other seven, the autors performed 3 decompressions followed by an excellent result, apart from in one case in which the nerve was markedly contused. In 2 cases a superficial cervical plexus graft and a XII-VII anastomosis proved necessary.

Adolescent↗

Laser applications in inner ear surgery.

Argon and carbon dioxide lasers can cause heat shrinkage of the membranous labyrinth without injury to hearing. The argon laser can penetrate the membranous labyrinth and cause destruction of targeted vestibula special sensory epithelium also without injury to hearing. Consequently, these lasers have been used successfully in two treatment techniques for benign paroxysmal positional vertigo, which are discussed in detail. The early techniques for laser assisted resection of the pars superior portion of the inner ear with hearing preservation are discussed.

Animals↗

[Neurologic manifestations in hereditary Osler-Rendu hemorrhagic telangiectasia].

The neurological manifestations of Osler-Rendu's syndrome observed in 10 patients were characterized by polymorph permanent of transient clinical pathology in the forms of subarachnoidal hemorrhages, ischemic disturbances of cerebral circulation, symptoms on the part of the brain stem, headaches, vestibular and convulsive disturbances. The cerebral disorders were caused by teleangiectases in the cerebral vessels, the fact, that was confirmed in 2 cases on autopsy. The cerebral teleangiectases may be the cause of a number of etiologically vague neurological syndromes (spontaneous subarachnoidal hemorrhages, etc.). While diagnosing the cerebral form of Osler-Rendu's syndrome one should take into consideration both neurological and somatic manifestations.

Adolescent↗

The vestibular system in the elderly.

Aging in the peripheral vestibular apparatus is shown to consist of processes similar to those occurring in other parts of the nervous system. Sensory epithelium and primary efferents degenerate and are not replaced. Type I hair cells and elements of the pars inferior are most susceptible. Remaining cells show a build-up of lipofuscin and microstructural changes suggesting compromised metabolism. Rupture of the saccular membrane and microfractures of the otic capsule are frequently seen. Otoconia undergo degeneration, and the tissue between the endolymphatic duct and bony vestibular aqueduct becomes fibrotic. The recognition of these findings is a first step in the clinical delineation of the "dysequilibrium of aging" from symptoms related to specific disease processes. Further clinical correlation will remain difficult until changes in the central vestibular pathways and their connections with the optic and locomotor systems are better understood.

Aging↗