Relationship of selected cognitive abilities to concept attainment and information processing.
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In this paper, a variant of the categorization-and-learning-module (CALM) network is presented that is not only capable of categorizing sequential information with feedback, but can adapt its resources to the current training set. In other words, the modules of the network may grow or shrink depending on the complexity of the presented sequence-set. In the original CALM algorithm, modules did not have access to activations from earlier stimulus presentations. To bypass this limitation, we introduced time-delay connections in CALM. These connections allow for a delayed propagation of activation, such that information at a given time will be available to a module at a later timestep. In addition, modules can autonomously add and remove resources depending on the structure and complexity of the task domain. The performance of this ontogenic CALM network with time-delay connections is demonstrated and analyzed using a sample set of overlapping sequences from an existing problem domain.
A fundamental problem in studying the neural mechanisms of odor recognition and discrimination in the olfactory system lies in determining the features or "primitives" of an odor stimulus that are analyzed by glomerular circuits at the first level of processing in the brain. Several recent studies support the idea that it is not simply the molecular features of odors that contain important information, but also the intermittent pattern of their presentation to the olfactory epithelium that helps determine the behavioral response to odor.
A computer network system has been developed in the Orthodontic Clinic, Osaka University Dental Hospital, to improve treatment efficiency and patient service. The system consists of a 32-bit host computer, its peripheral units, and personal computers connected to the host computer by data-transmission circuits, making up a local area network (LAN). It is possible in this system to integrate various types of data, such as the patient's basic information, treatment records, image data, and diagnostic analysis results to construct a relational database. It has been shown that the computer system developed in the orthodontic clinic has various clinical advantages.
The versatility of Ca2+ as a second messenger lies in the complex manner in which Ca2+ signals are generated. How information contained within the Ca2+ code is interpreted underlies cell function. Recently, we identified CAPRI and RASAL as related Ca2+-triggered Ras GTPase-activating proteins. RASAL tracks agonist-stimulated Ca2+ oscillations by repetitively associating with the plasma membrane, yet CAPRI displays a long-lasting Ca2+-triggered translocation that is refractory to cytosolic Ca2+ oscillations. CAPRI behavior is Ca2+- and C2 domain-dependent but sustained recruitment is predominantly Ca2+ independent, necessitating integration of Ca2+ by the C2 domains with agonist-evoked plasma membrane interaction sites for the pleckstrin homology domain. Using an assay to monitor Ras activity in real time, we correlate the spatial and temporal translocation of CAPRI with the deactivation of H-Ras. CAPRI seems to low-pass filter the Ca2+ signal, converting different intensities of stimulation into different durations of Ras activity in contrast to the preservation of Ca2+ frequency information by RASAL, suggesting sophisticated modes of Ca2+-regulated Ras deactivation.
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