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Is the organisation of goal-directed action modality specific? A common temporal structure.

With the help of kinematic analysis, the temporal organization of the complex daily activity 'drinking from a bottle with a glass' was described in detail. The analysis focused on the sequential action structure, the prehensile acts, and the bimanual coordination as well as on the effect of different instruction modalities on these parameters to explore the underlying representation for this complex action. Movements of the two arms were recorded in three-dimensional space with the help of an optoelectronic device in 12 normal subjects under four conditions: (1) action pantomime after verbal instruction; (2) action imitation after observation of the action performed by the experimenter without the objects; (3) action pantomime while seeing, but not touching the objects; and finally (4) action execution with objects. Despite high execution variability, the temporal structure of the action could be precisely described by the relative duration and peak velocity of action segments, by the MGA-object size-correlation, and by linear regression analysis between the onsets of functionally related action segments. A similar structure of the action as characterized by these kinematic parameters was retained across different instruction modalities. Only when the action was executed with the objects, the interval between the movement onsets of either hand and the peak velocity of the manipulative acts were reduced, while no change was observed across the other three instruction modalities. This stability of the temporal structure suggests the existence of a level in the representation of an action where all the modalities converge.

Attention↗

Recognition and imitation of pantomimed motor acts after unilateral parietal and premotor lesions: a perspective on apraxia.

We compared gesture comprehension and imitation in patients with lesions in the left parietal lobe (LPAR, n=5) and premotor cortex/supplementary motor area (LPMA, n=8) in patients with damage to the right parietal lobe (RPAR, n=6) and right premotor/supplementary motor area (RPMA, n=6) and in 16 non-brain damaged control subjects. Three patients with left parietal lobe damage had aphasia. Subjects were shown 136 meaningful pantomimed motor acts on a videoscreen and were asked to identify the movements and to imitate the motor acts from memory with their ipsilesional and contralesional hand or with both hands simultaneously. Motor tasks included gestures without object use (e.g. to salute, to wave) pantomimed imitation of gestures on one's own body (e.g. to comb one's hair) and pantomimed imitation of motor acts which imply tool use to an object in extrapersonal space (e.g. to hammer a nail). Videotaped test performance was analysed by two independent raters; errors were classified as spatial errors, body part as object, parapraxic performance and non-identifiable movements. In addition, action discrimination was tested by evaluating whether a complex motor sequence was correctly performed. Results indicate that LPAR patients were most severely disturbed when imitation performance was assessed. Interestingly, LPAR patients were worse when imitating gestures on their own bodies than imitating movements with reference to an external object use with most pronounced deficits in the spatial domain. In contrast to imitation, comprehension was not or only slightly disturbed and no clear correlation was found between the severity of imitation deficits and gesture comprehension. Moreover, although the three patients with aphasia imitated the movements more poorly than non-aphasic LPAR patients, the severity of comprehension errors did not differ. Whereas unimanual imitating performance and gesture comprehension of PMA patients did not differ significantly from control subjects, bimanual tasks were severely disturbed, in particular when executing different movements simultaneously with the right and left hands.

Adult↗

Imitation of gestures by disconnected hemispheres.

PU's corpus callosum was severed as a sequel of bleeding from an arteriovenous malformation. The lesion affects the truncus and the splenium and caused somatosensory and visual disconnection of the hemispheres. On clinical testing PU's left hand was apraxic for pantomime of object use but not for imitation. By contrast, when stimuli for imitation of meaningless hand and finger postures were presented tachistocopically to either the left or the right visual field, both hemispheres turned out to be apraxic in different ways. Imitation of hand postures was perfect for right-handed imitation of stimuli presented to the left hemisphere but defective in all other conditions. Imitation of finger postures was below the normal range in all conditions initially, but improved to normality for right-hand imitation of stimuli presented to the left hemisphere after repeated testing. After successful imitation of gestures presented to the left hemisphere PU commented that he imitated without really seeing the stimulus by "formulating the unseen", whereas after presentation to the right hemisphere he felt that he saw the stimulus but could not imitate. We propose that imitation of meaningless gestures affords a coding of gestures with reference to knowledge about body parts which can be applied only by the left hemisphere. Imitation of finger postures puts additional demands on fine grained visuospatial discrimination which necessitates a contribution by the right hemisphere.

Adult↗

The meaning of meaningless gestures: a study of visuo-imitative apraxia.

In two patients with damage to the inferior portion of the left angular gyrus severely defective imitation of meaningless gestures contrasted with preserved performance of meaningful gestures to verbal command and with preserved imitation of meaningful gestures. In one patient the imitation deficit was restricted to the imitation of hand positions while imitation of finger configurations was normal. In both patients replication of the hand positions on a mannikin was as defective as imitation on themselves. This pattern of preserved and impaired performances is incompatible with two-stage models of apraxia which posit that defective imitation stems from damage to an executional stage of gesture production. Interruption of a direct route from perception to execution of action could account for the dissociation between defective imitation of meaningless and preserved performance of meaningful gestures. We propose that functioning of this route requires the integrity of general knowledge about the structure of the human body.

Aged↗

Lexicon size and its relation to foot preference in the African grey parrot (Psittacus erithacus).

To study footedness in parrots, an international survey of parrot owners was conducted. Responses were obtained from 524 individuals, including 70 owners of African Grey parrots (all animals > or = 10 months old). All respondents were given a 10-item questionnaire and a standard method for testing foot preference in their pets, and they were asked to count the number of separate words in their pets' lexicons of human speech sounds. Right-footed African Greys (N = 36) had significantly larger lexicons than left-footed African Greys (N = 34; P = 0.01). This difference could not be accounted for by group differences in training efforts or socialization/housing with conspecifics. A non-significant trend in the same direction was found in a comparison sample of Amazon parrots, although these genera are less adept than African Greys at learning human speech sounds. Other investigators have provided convincing evidence of lateralization, in the avian brain, for the analysis and memory of differing types of stimuli. In addition, there appears to be preferential left hypserstriatal activation for long-term memory consolidation. Our results suggest a relationship between lateral asymmetry for motor preference and asymmetric CNS mediation of a 'higher cognitive' function (i.e. the categorization and long-term mnestic processing of human speech sound.

Animals↗

The left parietal cortex and motor attention.

The posterior parietal cortex, particularly in the right hemisphere, is crucially important for covert orienting; lesions impair the ability to disengage the focus of covert orienting attention from one potential saccade target to another (Posner, M. I. et al., Journal of Neuroscience, 1984, 4, 1863-1874). We have developed a task where precues allow subjects to covertly prepare subsequent cued hand movements, as opposed to an orienting or eye movement. We refer to this process as motor attention to distinguish it from orienting attention. Nine subjects with lesions that included the left parietal cortex and nine subjects with lesions including the right parietal cortex were compared with control subjects on the task. The left hemisphere subjects showed the same ability as controls to engage attention to a movement when they were forewarned by a valid precue. The left hemisphere subjects, however, were impaired in their ability to disengage the focus of motor attention from one movement to another when the precue was incorrect. The results support the existence of two distinct attentional systems allied to the orienting and limb motor systems. Damage to either system causes analogous problems in disengaging from one orienting/movement target to another. The left parietal cortex, particularly the supramarginal gyrus, is associated with motor attention. All the left hemisphere subjects had ideomotor apraxia and had particular problems performing sequences of movements. We suggest that the well documented left hemisphere and apraxic impairment in movement sequencing is the consequence of a difficulty in shifting the focus of motor attention from one movement in a sequence to the next.

Adult↗

A new model of sensorimotor coupling in the development of speech.

We present a computational model that learns a coupling between motor parameters and their sensory consequences in vocal production during a babbling phase. Based on the coupling, preferred motor parameters and prototypically perceived sounds develop concurrently. Exposure to an ambient language modifies perception to coincide with the sounds from the language. The model develops motor mirror neurons that are active when an external sound is perceived. An extension to visual mirror neurons for oral gestures is suggested.

Artificial Intelligence↗

The mirror neuron system and action recognition.

Mirror neurons, first described in the rostral part of monkey ventral premotor cortex (area F5), discharge both when the animal performs a goal-directed hand action and when it observes another individual performing the same or a similar action. More recently, in the same area mirror neurons responding to the observation of mouth actions have been also found. In humans, through an fMRI study, it has been shown that the observation of actions performed with the hand, the mouth and the foot leads to the activation of different sectors of Broca's area and premotor cortex, according to the effector involved in the observed action, following a somatotopic pattern which resembles the classical motor cortex homunculus. These results strongly support the existence of an execution-observation matching system (mirror neuron system). It has been proposed that this system is involved in action recognition. Experimental evidence in favor of this hypothesis both in the monkey and humans are shortly reviewed.

Animals↗

Family correlates of female adolescents' ego-identity development.

Past research has suggested that parents may contribute to the positive development of their daughter's identity formation. Theoretical notions from both social learning and symbolic interaction indicate that parents can either facilitate or hinder positive growth. Therefore, to test the predictions that (a) more mature (moratorium and achieved) identity status parents would have daughters with more mature identities, and (b) that both positive and negative parenting styles can be detected to differentiate between less (diffused and foreclosed) and more mature identity status youths, 45 families (145 subjects) were assessed on parent-child relations and identity status formation. In contrast to much past research, parent-child relations were assessed from both the adolescents' and the parents' perspectives. The findings indicate that parental identity status formation may have an effect on the adolescent's identity formation and that parent-child relations differentiate between less and more mature female adolescent identities.

Adolescent↗