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At least 1,189 records · Page 66Linked to original sources
PubMed2005

A review of the effect of occlusive dressings on lamellar bodies in the stratum corneum and relevance to transdermal absorption.

Transdermal drug delivery is becoming a widely used tool in the pharmaceutical industry. Many factors can influence the transdermal flux of medication from a transdermal drug delivery system. The recently described skin physiology of lamellar bodies and skin responses to occlusive dressings provide new insights into transdermal drug delivery. This paper reviews the literature on occlusive dressings and lamellar bodies as it relates to transdermal drug delivery. An understanding of the physiology of lamellar bodies is important to understand and improve transdermal drug delivery.

Absorption↗
PubMed1991

Wound dressings of the nineties: indications and contraindications.

A revolution in wound management has occurred over the past 3 decades. A plethora of wound care dressings appear to enhance the wound repair process in acute and chronic wounds. However, extensive research is needed to discriminate between the beneficial effects of increased attention to all aspects of patient care, including wound management, and the salutary effects of dressing materials.

Algorithms↗
PubMed1991

A hydrocolloid occlusive dressing plus triamcinolone acetonide cream is superior to clobetasol cream in palmo-plantar pustulosis.

The purpose of this study was to compare the therapeutic efficacy of a hydrocolloid dressing (Actiderm) over a medium strength corticosteroid (triamcinolone acetonide (TAA) 0.1% cream) with that of a highly potent corticosteroid (clobetasol propionate 0.05% cream) in palmo-plantar pustulosis and localized pustular psoriasis. It was a randomized, open, prospective, right-left comparative trial in 19 patients. The Actiderm dressing and the TAA cream were applied every third day, whereas the clobetasol cream was applied twice daily for 4 weeks. Both treatments resulted in a significant improvement. On completion of treatment, complete clearance was found in 13 patients (63%) with Actiderm plus TAA, but in only 3 patients (21%) with clobetasol (p = 0.001). Four weeks after stopping therapy, the clinical parameters had returned to their pre-treatment level, except for erythema on the Actiderm plus TAA treated lesions (p less than 0.05). No clinically important adverse effects were reported or observed; in particular there was no sign of skin atrophy at the end of study. The results of this study demonstrate that Actiderm applied over a medium strength corticosteroid every third day is highly effective against palmoplantar pustulosis and localized pustular psoriasis. However, it is necessary to develop treatment regimens to maintain the improvement achieved.

Adolescent↗
PubMed2006

Use of negative-pressure dressings to manage a difficult surgical neck wound.

We used negative-pressure dressings to treat a poorly healing cervical rotation flap following radical neck dissection in an elderly man. The wound had failed to heal properly after 2 weeks of conservative management. Following application of the negative-pressure dressings, the wound granulated quickly and healed well by secondary intention.

Aged↗
PubMedDate not supplied

Use of semiocclusive, transparent film dressings for surgical wound protection: experience in 3637 cases.

During an eight-year period, the author used a semiocclusive, transparent film surgical dressing as a protective cover for 3637 surgical incisions. The wet environment facilitated healing, and no patient exhibited any symptoms of wound infection. Compared with traditional methods, the semiocclusive dressing resulted in faster wound healing, decreased pain, and less scarring. It also permitted visual assessment of wound healing, as well as promoting patient mobility and hygiene.

Bandages↗
PubMed1990

Effects of placental dressing indolent ulcers.

Fifteen cases of indolent ulcers of varying aetiology were treated by human placental dressing. An equal number of patients treated with antibiotics were taken as control. Human placental dressing for chronic ulcers was found to be effective in wound healing, inexpensive, freely available and devoid of side-effects. The immunological response which produces the clinical results by the use of human placenta has been studied. The raised level of immunoglobulins in the form of IgG and IgM was also seen.

Adolescent↗
PubMed1990

[Does the elastic rapid wound dressing Ankerplast Spray modify wound healing?].

It had been tested if the elastic wound-dressing Ankerplast Spray reduces the risk of an infection of wounds, and if any influences could be observed on the formation of scars after spray-sealing of fresh surgical wounds. In a prospective, controlled study of 597 patients 567 could be postoperatively surveyed at all fixed terms of control up to the 56th day. The infection rate of wounds after general surgical operations amounted to a total of 7 per cent. The rate of hypertrophic scars within the control group was with 11 per cent respectively 7 per cent significantly below the rate of 34 per cent of hypertrophic scars within the Spray group. Are fresh surgical operation wounds being sealed with the elastic wound-dressing Ankerplast Spray no influence can be observed on the postoperative risk of wound infections. Hypertrophic scars must be taken in consideration in about 34 per cent.

Acrylates↗
PubMed1990

Clinical evaluation of a polymeric membrane dressing in the treatment of pressure ulcers.

The healing effects of the Ferris polymeric membrane dressing were tested in a 70-day evaluation of 18 ulcers on 13 elderly subjects with Stage I, II, and III pressure ulcers. The mean length of time these ulcers had been present prior to the trial dressing was 144 days with 50% of the ulcers (n = 9) present for 75 days or longer. Over 60% of the ulcers were completely healed and over 94% were improved during the study.

Aged↗
PubMedDate not supplied

[Treatment with Varihesive dressings of various types of leg ulcers].

Fourteen patients with leg ulcers of different aetiology are evaluated. The risk factors are analyzed and a complete vascular exploration of their extremities is performed and local exploration of the ulcer is carried out. Our study confirms the general opinion that healing of the foot in patients with ankle pressures of less than 50 mmHg or 70 mmHg in diabetics is very unlikely. Although, the results achieved after treatment have shown that trophic problems are not only related to arterial insufficiency. Other aspects interact with the tissue regeneration and as a consequence in the prognostic of the ulcer. It has been proved that occlusive treatment with hydrocolloid dressings has important advantages over other similar products, or compared to the conventional dressings, in the local treatment of vascular aetiological ulcers.

Adult↗
PubMed1987

The newer surgical dressings and wound healing.

In summary, there are a variety of new synthetic surgical dressing materials available today. Although individual physician preferences and differences in the type of injury may determine which of these membranes is utilized in a given clinical situation, they all serve to speed the rate of epithelialization, to decrease motion within the healing wound, to decrease postoperative pain, and to minimize the potential for bleeding and infection. For all of these reasons, a complete knowledge of these dressings and their uses will greatly enhance the surgeon's ability to care more satisfactorily for the patient with a cutaneous wound.

Bandages↗
PubMed1987

Management of psoriasis vulgaris with a hydrocolloid occlusive dressing.

Because clinical improvement of psoriasis vulgaris was recently observed after the prolonged application of tape, 26 patients with symmetric plaque-type psoriasis were enrolled in a prospective bilateral comparison study evaluating the clinical efficacy of the adhesive hydrocolloid occlusive dressing (HCD). The majority of localized plaques of psoriasis achieved improvement (41%, 14/34) or resolution (47%, 16/34) with the prolonged application of HCD; also, HCD was therapeutically superior to twice-daily applications of fluocinolone acetonide cream, and was comparably effective as erythemogenic ultraviolet B treatment. Although the therapeutic mechanism is not completely understood, occlusive dressings have great potential in the management of limited psoriasis vulgaris.

Adhesives↗
PubMed1987

Occlusive dressings.

Occlusive dressings reduce or eliminate wound pain, increase the speed of reepithelialization in acute wounds and stimulate debridement and healing of chronic ulcers. During the first 10 to 14 days, a large amount of fluid may accumulate under the dressing, but this fluid is seldom the result of infection. Films, foams, hydrocolloids and hydrogels have different properties that commend them in different settings.

Colloids↗
PubMed1985

Multicenter clinical evaluation of a hydrocolloid dressing for leg ulcers.

The need for a moist environment for the normal healing process led to the development of occlusive dressings. Results from this study support the contention that a moist wound environment is favorable to the healing process in humans as well as in animal models. Hydrocolloid dressings are effective in the practical daily management of chronic and even refractive ulcerations of the lower extremities and offer a time-saving treatment alternative with a high degree of patient acceptability.

Adolescent↗
PubMed1985

Clinical evaluation of a new occlusive hydrocolloid dressing.

Eighteen patients with a total of twenty-four dermal ulcers of varying causes and unresponsive to other conservative treatment were treated with a new hydrocolloid dressing. All lesions healed in less time than with other modalities. This hydrocolloid dressing is more effective than others presently available for the treatment of noninfected dermal ulcers.

Aged↗
PubMed1983

Use of a semi-permeable membrane dressing in donor sites in Nigerians.

Most published studies on the use of a semi-permeable membrane dressing (opsite) on split-skin donor sites have been on Caucasians. To assess this new method on the black population of a developing country where donor sites are notoriously slow to heal, a study was conducted on fifty Nigerians of varying age groups in whom split-skin grafts of identical thickness were taken from both thighs by the same surgeon: 100 donor sites were studied. In all the patients one thigh was dressed with the conventional sofratulle and the other with opsite. The allocation was made randomly. Twenty-five donor sites (53.4%) treated with sofratulle healed by the 13th postoperative day. By contrast, thirty donor sites (62.5%) treated with opsite healed by the 7th postoperative day. All opsite treated wounds were completely healed by the 11th day but it took nearly four weeks for the sofratulle treated thighs to heal. Minimal discomfort was experienced by 10% of the patients treated with opsite but about 80% of those treated with sofratulle required mild analgesics on ambulation during the first 48 hours on account of pain. Opsite effectively reduces healing time in donor sites, is easy to apply, less bulky to use, painfree and well tolerated by patients.

Adolescent↗
PubMed1984

Amniotic membranes as a temporary wound dressing in necrotizing fasciitis.

A diabetic patient was seen at Magee-Womens Hospital with a vulvar abscess extending to the abdomen. Necrotizing fasciitis was diagnosed at operation, and the involved tissue was widely excised. The authors describe the successful use of amniotic membranes as a temporary wound dressing. The benefits of this method over conventional gauze dressings are easy availability, better adherence to the wound, less pain, and negligible cost to the patient.

Abscess↗
PubMed1981

Foam elastomer dressings in surgery.

A wound dressing prepared from silicone which is catalysed by a gas-producing activatory is described. The resultant foam elastomer is soft, comfortable and easy to prepare, and can be removed, cleaned and reinserted by the patient with minimal instruction and formality. It promises to be a highly cost-effective dressing, with a particularly wide range of potential applications.

Adult↗