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Observations on a new collagen barrier membrane in 16 consecutively treated patients. Clinical and histological findings.

BACKGROUND: Space-maintaining capacity, cell disclusive potential, and stability over time are crucial factors to achieving sufficient bone augmentation with membrane barriers. The case series presented here assessed a new collagen barrier used in bone augmentation. Clinically, the healing pattern, especially in cases of secondary healing, was studied. METHODS: Soft tissue healing was documented by photographs, and the size of the dehiscences calculated by image analysis. The measurements were performed on digitized photographs. During reentry, barrier remnants were dissected and histologically evaluated. RESULTS: The mean value for dehiscences was 35.5 mm2; all dehiscences healed within 4 weeks after the exposure became evident. The difference was statistically significant between the week 2 and week 6 visits (P = 0.008) for each previously exposed site. The histologic observation of barrier remnants revealed direct apposition of fibrous and bone tissues on the membrane surface. CONCLUSION: In cases of membrane exposure, gingival dehiscences always disappeared in the following weeks without affecting the healing process. Histologic results showed barrier stability over a 6-month period, promoting bone regeneration.

Adult↗

Moving an ankylosed central incisor using orthodontics, surgery and distraction osteogenesis.

When a dentist replants an avulsed tooth, the repair process sometimes results in the cementum of the root and the alveolar bone fusing together, with the replanted tooth becoming ankylosed. When this occurs, the usual process of tooth movement with bone deposition and bone resorption at the periodontium cannot function. If dental ankylosis occurs in the maxillary incisor of a growing child, the ankylosed tooth also cannot move vertically with the subsequent vertical growth of the alveolar process. This results in the ankylosed tooth leaving the plane of occlusion and often becoming esthetically objectionable. This report describes a 12-year-old female with a central incisor that was replanted 5 years earlier, became ankylosed, and left the occlusal plane following subsequent normal vertical growth of the alveolar process. When growth was judged near completion, the tooth was moved back to the occlusal plane using a combination of orthodontics, surgical block osteotomy, and distraction osteogenesis to reposition the tooth at the proper vertical position in the arch. This approach had the advantage of bringing both the incisal edge and the gingival margin of the clinical crown to the proper height in the arch relative to their antimeres. Previous treatment procedures for ankylosed teeth have often involved the extraction of the affected tooth. When this is done, a vertical defect in the alveolar process results that often requires additional bone surgery to reconstruct the vertical height of the alveolar process. If the tooth is then replaced, the replacement tooth must reach from the final occlusal plane to the deficient ridge. This results in an excessively long clinical crown with a gingival height that does not match the adjacent teeth.

Alveolar Process↗

Microvessel density and vascular endothelial growth factor expression in sinus augmentation using Bio-Oss.

AIM: The aim of this study was to evaluate microvessel density (MVD) and vascular endothelial growth factor (VEGF) expression in sinus augmentation with Bio-Oss. METHODS: Twenty patients participated in this study. The sinuses were filled with 100% Bio-Oss. Implants were inserted after 3 months in group A, and 6 months in group B. A trephine was used to harvest bone cores. As control, the pre-existing subantral bone was used. RESULTS: The mean MVD in control bone was 23.6 +/- 1.8. In the sites augmented with Bio-Oss, at 3 months, the MVD was 23.3 +/- 2.1, while in the sites retrieved at 6 months the MVD was 29.5 +/- 2.4. The difference in MVD between the control bone and group A was not statistically significant. The difference between the control bone and group B was statistically significant (P < 0.05). The statistical analysis showed that the difference in MVD between group A and group B was statistically significant (P < 0.05). CONCLUSIONS: Bio-Oss seemed to induce an increase in MVD that reached a higher value after 6 months. The percentage of vessels positive to VEGF was higher in group A than in group B. Our data also showed a higher percentage of vessel and stromal cells positive to VEGF and higher MVD values in areas where there was newly formed bone compared with areas where maturation processes were occuring, and this fact could point to a close spatial relationship between angiogenesis and osteogenesis.

Adult↗

Alveolar cavitational osteopathosis. Manifestations of an infectious process and its implication in the causation of chronic pain.

A recently discovered oral disease process of infectious origin, characterized by nonradiographically detectable, hollow, pathologic, alveolar cavitational lesions of significant size, is described. This oral infectious disease process, termed alveolar cavitational osteopathosis, is causally implicated not only in the genesis of certain craniofacial pain syndromes, among them idiopathic trigeminal neuralgia and atypical facial pain, but also in chronic pain syndromes remote from the craniofacial region including the back, chest, arms, legs and cervical areas. A diagnostic process is presented which serves to define the locus of nonradiographically detectable alveolar cavitational osteopathosis and correlates a given pathological site to a given area of pain. Comprehensive schematics have been developed defining the pain pathways emanating from the oral cavity and their specific relationship to sites of perceived pain both in the craniofacial region and other areas of the body. The treatment modality described serves to induce bone growth within the cavitational lesions, resulting in the subsequent eradication of the cavity. The abolition of osteopathosis results in significant or total disappearance of pain symptomatology.

Alveolar Process↗

[The effect of radiation on the chronology of extraction wound healing. Histomorphologic study in rats].

The purpose of this study was to analyse histomorfologically the X-radiation influence on the chronology of wound healing of tooth extraction. Sixth young albino rats were used. After extracting the maxillary right incisors all the rats, three experimental groups were formed: the control (I) and the groups that received 1.25 Sv (II) and 1.75 Sv (III). The rats were killer at 3, 7, 14 and 28 post-operative days following the teeth extraction. The pieces obtained were submitted to routine laboratorial procedures until getting pieces stained with hematoxylin and eosin. It was concluted that: 1) there was a delay in the epithelial proliferation of the gengival mucosa o the animals submitted to X-rays, in a similar way in the two irradiated groups: 2) there was a considerable delay in the alveolar repair process in dental extraction wound; 3) this delay was more proeminent when the X-ray action was more intense.

Alveolar Process↗