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At least 1,189 records · Page 66Linked to original sources
PubMed1990

Prevalence and clinical importance of Entamoeba histolytica in two high-risk groups: travelers returning from the tropics and male homosexuals.

This study was undertaken to learn the prevalence of amebiasis and to assess the clinical importance of Entamoeba histolytica in two high-risk groups: 2700 travelers returning from the tropics and 320 male homosexuals. Some 16.3% of the homosexual men and 4.0% of the travelers had E. histolytica infections. Only five travelers showed a pathogenic zymodeme of E. histolytica, which correlated closely with invasive amebiasis with positive amebic serology and clinical symptoms with diarrhea. The homosexual group had neither a pathogenic isoenzyme pattern nor positive amebic serology. Currently, travelers to the tropics have a risk of 0.3% (1:340) of acquiring invasive amebiasis; 92.5% of all E. histolytica infections in travelers remain asymptomatic and are confirmed by serology and zymodeme status. No homosexual presented with invasive amebiasis.

Adult↗
PubMed1983

Sexually transmitted diseases in homosexual men.

Due to the number of sexual encounters and variety of practices, men who have homosexual experiences have increased incidence and prevalence rates of many diseases. Diseases that are covered here include hepatitis A and B, syphilis, gonorrhea, condylomata accuminata, herpes simplex, AIDS (acquired immune-deficiency syndrome) and several enteric diseases, namely amebiasis, giardiasis, shigellosis and salmonellosis. An overview of each disease is included along with diagnostic testing and treatment regimens. This report concludes with a system of risk assignment and recommendations for frequency of sexually transmitted disease screening.

Amebiasis↗
PubMed1977

Isolation and experimental infection of free-living amebae in freshwater fishes.

Twenty-three species of fish from nine southeastern states were screened for the presence of small, free-living amebae. Organs from 11 species of fish contained amebae of the genera Acanthamoeba, Naegleria, and Vahlkampfia. Three strains of Acanthamoeba were injected into fish to determine infectivity and pathogenicity of the amebae. Strains used were an A. polyphaga MC-1 isolated from the spleen of a bass, the pathogenic A-5 strain of A. culbertsoni, and the pathogenic Lilly A-1 strain of A. culbertsoni. The MC-1 strain established systemic infections in many organs of the test fish. The 2 strains of A. culbertsoni did not produce any infection in fish under the laboratory conditions.

Amebiasis↗
PubMed1997

Ileal amoebiasis.

Whilst colonic amoebiasis and its complications are well-documented, ileal amoebiasis has not been described in the literature. We report the cases of two patients with ileal amoebiasis and outline their management and outcome. It is important that surgeons working in areas endemic for amoebiasis be mindful of this entity.

Adult↗
PubMed1984

Caerulomycin, an antifungal antibiotic with marked in vitro and in vivo activity against Entamoeba histolytica.

The anti-amoebic action of the bipyridyl antibiotic caerulomycin was assessed in vitro and in vivo using various strains of Entamoeba histolytica from polyxenic, axenic and monoxenic cultures. Minimum inhibition concentrations of caerulomycin (metronidazole) were 7.5 (5), 15.6(1.95) and 60 (2.5) micrograms/ml against polyxenic, axenic and monoxenic cultures of E. histolytica, respectively. The ED50 values ascertained in golden hamsters (extraintestinal amoebiasis) and rats (intestinal amoebiasis) after the oral route were 136 and 199 mg/kg (X4), respectively. Metronidazole proved to be approximately four times more active against tissue forms of E. histolytica than caerulomycin [ED50 of metronidazole: less than 40 mg/kg (X4)]. The antibiotic was slightly superior to metronidazole in its action on lumen forms of E. histolytica [ED50 of metronidazole: 233 mg/kg (X4)]. The antibiotic was in some cases toxic to hamsters and rats within the therapeutic range.

2,2'-Dipyridyl↗
PubMed1983

Entamoeba histolytica causes intestinal secretion: role of serotonin.

Lysates of the protozoan parasite Entamoeba histolytica altered active electrolyte transport when present on the serosal surface of rabbit ileum and rat colon. The lysate-induced effects on electrolyte transport were similar to those caused by serotonin, and were blocked by bufotenine, an analog known to inhibit the action of serotonin. The transport effects were partially inhibited by antibody to serotonin. The amebic lysates were shown to contain serotonin by radioimmunoassay, high-performance liquid chromatography, and thin-layer chromatography. These results suggest that the serotonin present in Entamoeba histolytica may be important in the diarrhea seen in amebiasis.

Amebiasis↗