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PubMed1988

[Dura mater healing after repair with aponeurotic plasty. Comparison of results between classical sutures and fibrin adhesive glue. Fibrin adhesive in frontobasal injuries. An experimental study].

The aim of the present experimental study was to compare the quality of the healing obtained with fibrin glue or with classical sutures to repair post-traumatic fronto-basal fistulae. The anterior part of the cranial base and a piece of dura mater are removed. The first group of rabbits (n = 26) is repaired with fibrin glue; the second group with separate sutures. The postoperative controls are realised by injection of 1 ml patent blue in the cisterna magna to detect C.S.F. rhinorrhea, x-ray study of the cranial bases and histological samples of transversal slices of the cranial base. The different biological findings seem to be important arguments to confirm the useability and trustworthiness of human origin fibrin glues to close meningeal wounds.

Animals↗