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Ethnic differences in self reported health in Malmö in southern Sweden.

STUDY OBJECTIVE: The aim of this study was to investigate ethnic differences in self reported health in the city of Malmö, Sweden, and whether these differences could be explained by psychosocial and economic conditions. DESIGN/SETTING/PARTICIPANTS: The public health survey in Malmö 1994 was a cross sectional study. A total of 5600 people aged 20-80 years completed a postal questionnaire. The participation rate was 71%. The population was categorised according to country of origin: born in Sweden, other Western countries, Yugoslavia, Poland, Arabic speaking countries and all other countries. The multivariate analysis was performed using a logistic regression model in order to investigate the importance of possible confounders on the differences by country of origin in self reported health. Finally, variables measuring psychosocial and economic conditions were introduced into the model. MAIN RESULTS: The odds ratios of having poor self reported health were significantly higher among men born in other Western countries, Yugoslavia, Arabic speaking countries and in the category all other countries, as well as among women born in Yugoslavia, Poland and all other countries, compared with men and women born in Sweden. The multivariate analysis including age and education did not change these results. A huge reduction of the odds ratios was observed for men and women born in Yugoslavia, Arabic speaking countries and all other countries, and for women born in Poland after the introduction of the social network, social support and economic factors into the multivariate model. CONCLUSIONS: There were significant ethnic group differences in self reported health. These differences were greatly reduced by psychosocial and economic factors, which suggest that these factors may be important determinants of self rated health in certain minority groups.

Adult↗

[Thermostability and immunogenicity of trivalent oral poliovirus vaccine produced by different countries].

Hep-2 cell-based microtiter assay system was used to test the titer of TOPV(Sabin strain). Before immunization, the overall potency results of TOPV produced by China, Yugoslavia, and Belgium were 6.38, 6.25, and 5.75 log TCID 50/0.1 ml, respectively. After storage at 37 degrees C for 2 days or after 5 cycles of freezing and thawing, the overall titer of each TOPV reduced less than 0.5 log TCID 50/0.1 ml. A randomized study was conducted in Anhui Province to test the serological difference among the TOPV which were produced by China, Yugoslavia and Belgium. The formulations of the TOPV produced by China and Yugoslavia were 6.0, 5.0, and 5.5 log TCID 50/0.1 ml of Sabin types 1, 2, and 3, respectively. All of the children in this study were divided into three groups, and children in group A, B, and C received TOPV produced by China, Yugoslavia, and Belgium, respectively. Three doses of TOPV were given to the children in the group at 2, 3, and 4 months of age. The seroconversion rates and geometric mean titers had no significant differences among these groups before immunization. At the end of one month following the 2nd dose, the rates of seroconversion to type 1-3 poliovirus in group A, B, and C were 88%, 98%, 98%; 92%, 98%, 92%; 100%, 100% and 96%, respectively. The rate of seroconversion to type 1 poliovirus in group C was higher than those in group A and B.(ABSTRACT TRUNCATED AT 250 WORDS)

Antibodies, Viral↗

Epidemiology and treatment of renal pelvic and ureteral tumors.

Throughout the world the number of cases of renal pelvic and ureteral tumors has increased considerably during the last 2 decades. In Yugoslavia this increase has been exceptionally high since about 1953 or 1954. Many of our patients with these tumors come from regions where the population is affected by endemic nephropathy, the frequency of tumors in these regions being about 100 times higher than it is in other parts of Yugoslavia. In many cases these patients have renal failure and, therefore, conservative procedures are undertaken. Herein are reported the causes and results of therapy in 972 cases of renal pelvic and ureteral tumors collected in Yugoslavia. Particular attention has been paid to conservative operations (37 cases of renal pelvic and 64 cases of ureteral tumors), including their indications and possibilities. That many patients with renal pelvic and ureteral tumors have favorable conditions for a conservative procedure is confirmed by the comparatively good followup. However, in other cases a conservative operation is unreasonable and nephroureterectomy is mandatory.

Acute Kidney Injury↗

Attitude of involved epidemiologists toward the first European outbreak of rhinosporidiosis.

Rhinosporidiosis occurs extremely seldom in Europe. Until recently, the disease was unknown in Serbia (Yugoslavia). An outbreak that began in January 1992, affected 21 individuals. All of them had been exposed to the same source of stagnant water. The purpose of this study was to assess which control measures would be selected by epidemiologists potentially involved in the control of the disease. Most respondents (20 of 32 or 62.5%) opted only for an information release as the most appropriate control measure. The reasons listed by the epidemiologists to justify their choice of optimal control measures showed that the political and economic hardships, including an embargo imposed upon rump Yugoslavia, did not hamper their judgment. The turmoil associated with the disintegration of Yugoslavia, however, appears to have significantly affected the information level of the participants.

Attitude of Health Personnel↗

Western personality models applied in Eastern Europe: Yugoslav data.

In this study, two leading "Western" models of personality developed in the United States are tested in Eastern Europe, specifically in Yugoslavia. First, the models were tested psychometrically, for their construct validity and cross-cultural applicability. Next, these Western personality models were used to explore the underlying structure of axis II syndromes of personality disorder as observed in Yugoslav patients. Finally, the models were tested regarding their ability to diagnose and discriminate categorical diagnoses of axis I mental disorders (e.g., depression, anxiety, and psychoses). The Five Factor Model of personality and the Seven Factor Model of temperament and character were applied to normal subjects and clinical patients with categorical axis I and axis II diagnoses (depression, anxiety, psychosis, and personality disorder), at the Institute for Psychiatry, University of Belgrade, Yugoslavia. The sample included 120 subjects: 90 hospitalized psychiatric patients and 30 normal subjects. The patients were females, from 20 to 45 years of age, classified into three groups: 30 with depression, 30 with various anxiety syndromes, and 30 with psychosis (primarily patients with schizophrenia, paranoid type in remission). The results indicated solid psychometric validity of the two Western personality models in the ethnically and culturally different setting of Yugoslavia. Important diagnostic and structural relationships between dimensions of personality and axis I and II categorical diagnoses were observed. As expected, certain combinations of personality traits allowed for diagnosis, description, and discrimination of personality disorder subtypes. As a novel finding, personality traits discriminated anxious, depressive and psychotic axis I disorders.

Adult↗

Obesity among female adolescents in Vienna, Austria--the impact of childhood weight status and ethnicity.

OBJECTIVE: The objective of the study was to analyse prevalence of overweight and obesity among migrant girls in Vienna, Austria, starting at the age of 6 years up to the age of 15 years. DESIGN: In a longitudinal study, the prevalence of overweight and obesity among migrant girls from Turkey and former Yugoslavia was documented and compared with that among Austrian girls in Vienna. SETTING: Medical investigation of medical school authority in Viennese schools. SAMPLE: Seven hundred and ninety girls of low socio-economic status were included in the study. METHODS: Anthropometric data were collected at the age of 6, 10 and 15 years. Body mass was estimated by means of the body mass index (BMI), and percentile curves were used for determining the weight status. MAIN OUTCOME MEASURE: Stature, body weight, BMI, weight status. RESULTS: The prevalence of overweight and obesity was significantly higher among migrant girls at all age groups. The highest percentage of overweight was found among 10-year-old girls from Yugoslavia (nearly 35%) and the lowest percentage of overweight was exhibited in 6-year-old Austrian girls (20%). Being overweight or obese at the age of 6 years increased the risk of being overweight at 10 and 15 years significantly (P < 0.001). Among migrants, this risk was significantly higher than among Austrian girls (P < 0.001). Only 64.8% of Austrian girls, who were overweight/obese at the age of 6 years, were still classified as overweight at the age of 15 years. Among migrant girls, who were overweight at the age of 6 years, 72.0% (Turkish girls) and 78.3% (Yugoslavian girls) remained overweight until the age of 15 years. CONCLUSIONS: Especially girls from former Yugoslavia but also Turkish girls exhibited high rates of overweight and obesity. Prevention should start as early as possible since overweight tends to persist from childhood into adolescence.

Adolescent↗

Infectious diseases mortality in central Serbia.

STUDY OBJECTIVE: To determine the influence and the effect of the war in the former Yugoslavia and of the United Nations economic sanctions on mortality from infectious diseases. DESIGN: This was a descriptive study analysing mortality data time series. SETTING: Central Serbia, Yugoslavia. PARTICIPANTS: The population of central Serbia was the subject of the study (about six million inhabitants). MEASUREMENTS: Mortality rates were standardised directly, using the "European population" as the standard. Regression analysis and analysis of covariance were undertaken. MAIN RESULTS: During the period 1973-93, mortality from infectious diseases showed a decreasing trend. From 1987-90, and infectious diseases was significantly higher than expected on the basis of the trend for the preceding period (p = 0.020 and p = 0.00). In addition, there was a statistically significant departure from the preceding trend (p = 0.036) in men between 1991 and 1993 (the period of the war and UN sanctions)--the main effect being in younger age groups. CONCLUSION: The economic crisis in the former Yugoslavia during the 1980s followed by the outbreak of the war and the damaging effects of UN economic sanctions had a distinctly adverse effect on mortality from infectious diseases.

Adolescent↗

[Deliveries in the outpatient birthing facility in Ruma during 1989 and between 1992 and 1995].

INTRODUCTION: The outpatient maternity home in Ruma offers health care to women during normal delivery. On the occasion of patient's admittance into the maternity home, indications for hospitalization during the delivery are strictly observed. Ruma community is a bordering area of SR Yugoslavia and, in the period of the war in ex Yugoslavia, it gave shelter to a great number of refugees and exiles. Health care was offered to pregnant women and to the ones who were giving birth and to the refugees in the Health Centre Ruma. The period from 1992-1996 is characterized by war, migration of people, UN sanctions imposed on Yugoslavia and low standard of living. PURPOSE: The purpose of this paper was to find out if there was a difference in indices regarding pregnancy and course of delivery in 1989 and in the period 1992-1996 in the Ruma and Irig communities population and in refugees and exiles. MATERIAL AND METHODS: The data were collected from the obstetrical records in outpatient maternity home Ruma in 1989 and 1992-1996. By data processing the following parameters were obtained: number of deliveries, percentage of spontaneous miscarriages and premature births, percentage of pregnancy-induced hypertension (PIH) and anemia in pregnancy, the rate of early neonatal morbidity and mortality; weight, length, circumferences of head and chest with the newborn infants. RESULTS: There were 321 deliveries in 1989; 12 women gave birth with PIH (3.73%). 37 women had a spontaneous miscarriage (11.52%). Anemia was corrected with 12 women after delivery (3.73%). There was one premature birth in 1989 (0.3%). 4 newborn infants were hospitalized after delivery (12.46 promiles). There was no mortality of the newborn infants and mothers. The following has been established for women giving birth in the period 1992-1996 from the territory of Ruma and Irig communities: number of deliveries (in 1992--563, in 1993--503, in 1994--481, in 1995--418) constantly falls. The percentage of PIH in pregnancy was 19.54% in 1992 (110 women) and 0.18% eclampsia (1 case), 11.3% (56 women) in 1993, 5.61% (27 women) in 1994, 5.82% (31 women) in 1995. In 1992 80 women giving birth had spontaneous miscarriages in their previous pregnancies (14.2%), in 1993--44 women (8.74%), in 1994--38 women (7.9%) in 1995--45 women (8.45%). An anemia correction after delivery was with 31 women (5.5%) in 1992, in 1993 with 24 women (4.26%), in 1994 with 18 women (3.74%) and in 1995 with 30 women (6.24%). There were 22 premature births in 1992 (3.9%), in 1993--7 (1.39%), in 1994--10 (2.07%) and in 1995--9 (1.69%). 14 children were hospitalized after delivery in 1992 (24.86 promiles), in 1993--20 children (39.76 promiles), in 1994--18 children (37.42 promiles), in 1995--35 children (65.7 promiles). In 1992 one child died after delivery because of left heart hypoplasia and pneumonia; in 1993 one woman delivered fetus mortus: one child died, in 1994, with diaphragmatic hernia and lung hypoplasia; in 1995 there were no deaths after delivery. Mothers' mortality was 0. In the period from 1992-1996, 62 women from Republic of Serb Krajina (hereinafter referred as RSK) were delivered and 67 women from Serb Repubic (hereinafter referred as SR). 5 women from RSK had a spontaneous misciarriage (8.06%), and 4 women from SR (5.97%). 8 women (12%) from RSK had PIH, and 5 women (7.46%) from SR. There were premature births with 3 women (4.82%) from RSK and with 2 women (2.98%) from SR. 2 newborn infants (32.25 promiles) from RSK were hospitalized after delivery and 3 (29.8 promiles) from RS. In 1995 one women delivered fetus mortus in utero (diabetica fetopathy) (14.9 promiles) from RSK. DISCUSSION: By analyzing the deliveries in the course of 1989 and in the period 1. 01. 1992 to 31. 12. 1995 the following has been established: the number of deliveries is greater in the period 1992-1996 in relation 1989, but there is a constant fall from 1992-1996. (ABSTRACT TRUNCATED)

Ambulatory Care Facilities↗

[Trends in mortality in Serbia, excluding the provinces, 1973-1994].

The war and break up of former Yugoslavia began in 1991. In May 1992 the United Nations imposed economic sanctions on Serbia and Montenegro which were suspended only in November 1995. The purpose of this study was to assess the effects of the war and UN sanctions on health of the population of Serbia without the provinces of Vojvodina and Kosovo. The period 1973-1994 was studied. Mortality data were derived from unpublished and published materials of the Federal Institute of Statistics [1]. Refugees, who, because of civil war, came to Serbia and Montenegro from other parts of former Yugoslavia, were not counted as a part of the population when mortality rates were calculated. Mortality rates were standardized directly using the "European population" as the standard [2]. The least square method was used to fit mortality rates to different trend curves. Linear trend was used whenever it significantly (p < 0.05) demonstrated the existing mortality rates. To measure the possible effect of the war and sanctions (WAS) on mortality between 1991 and 1994, dummy variable (variable WAS) consisting of 0's and 1's was made to signify the passage from the period before and the period after the beginning of the war and sanctions [3]. Over the period 1991-1994, characterized by the war and UN sanctions, in women aged 25-34, 35-44 and 75-84, total mortality was significantly higher than expected on the basis of the trend for the preceding period (p = 0.006, p = 0.000 and p = 0.015 respectively). The opposite effect was found in the age group 85+ (p = 0.012)/Table 2. Of major causes of death, in age group 25-34, mortality from endocrine diseases increased more rapidly in both sexes (p = 0.000) and mortality from urogenital diseases in women decreased more slowly than expected (p = 0.006). On the other hand, in age group 85+ mortality was significantly lower for cardiovascular diseases in both sexes (p = 0.035 and p = 0.006), for respiratory diseases in men (p = 0.011) and for neoplasms in women (p = 0.006)/Table 4. In addition, in the years 1991 and 1992 the increase in mortality from injuries and poisoning was evident in men aged 15-24, 25-34 and 85+ years (Graph 5). Our results show that over the period 1991-1994 changes in mortality were present in some age groups and were caused by certain groups of diseases. In men, besides mortality of infectious disease which decreased more slowly during 1991-1993 than expected, [4], the main departures were found in the mortality from injuries and poisoning and in mortality from endocrine diseases. The excess of death due to injuries and poisoning in the age group 15-34 can be explained as a direct consequence of the war. There were no military operations on the territory of Serbia, but young men from Serbia were nevertheless engaged in the war in other republics of former Yugoslavia. The outstanding increase in mortality caused by injuries and poisoning in men aged 85+ has two explanations. The first is the fact that suicide rate which was on an average of 86 per 100,000 over the period 1984-1990 rose to 140 per 100,000 during the period 1991-1993. In the year 1994 it fell to 92 per 100,000. Since there were no great differences in percent distribution of suicides among all deaths caused by injuries and poisoning in the two periods (27% in 1984-1990 and 20% in 1991-1993), it is clear that the rise of suicidal rate cannot be the only explanation for increased mortality from injuries and poisoning. In a situation when medical services were badly overextended (lack of medical equipment and proper maintenance of the existing equipment, lack of drugs and other medical inputs, a large number of wounded coming from Bosnia as well as numerous refugees) [5, 6], priority had to be given to younger age groups. Higher mortality due to endocrine diseases in men and women aged 25-34 years and higher mortality due to urogenital diseases in women of the same ages can be most probably attributed to poor medical supplies. Although formally excluded from the international economic blockade medical supplies were in practice badly affected by the fact that the dinar was rendered almost worthless and the Ministry of Health could no longer pay the medical inputs. In addition, bureaucratic hurdles of getting clearance from the UN added months of delay and made foreign companies unwilling to trade [5, 7]. The supply and distribution of drugs within the country was also irregular because communication lines were cut and local companies were not prepared to risk distributing drugs that nobody could pay for [7]. Higher than expected mortality in women aged 25-44 over the period 1991-1994 could be probably explained by their higher vulnerability (period of fertility) and the fact that the main burden of family survival was on them, so they had no time to think and to take care of their health. (ABSTRACT TRUNCATED)

Adolescent↗

[Total and natural population increase in Croatia].

Population developments in Croatia are examined over the period 1857-1981. The main focus is on trends since World War II. The authors note that from 1948 to 1981 "the population in Croatia grew more slowly than in other republics and provinces of Yugoslavia: it increased by 21.7% (in Yugoslavia by 41.6%) and the participation of Croatia's population in the total population of Yugoslavia decreased from 23.9% to 20.5%." Regional differences within Croatia are also analyzed. (SUMMARY IN ENG AND RUS)

Demography↗

[Critical review of drugs in 1990].

New chemical entities approved abroad (43) and in Yugoslavia (37) were presented. Discussions on several "old" drugs (41) open at the Yugoslav Federal Drug Committee for any reason (new formulation, new dose, new packaging, dosage regimen or indication) and renewal of registration (114) were also included. Special attention was given to the drugs which had been refused the renewal of registration (8). Critical drug re-evaluation as an important element of the improvement of pharmacotherapy was emphasized. A total of 78 drugs was discussed or registered in 1990-1.28% of drugs from the group A (vancomycin), 10.2% from the group B (aclarubicin, dexfenfluramine, warfarin, alprazolam, colestipol, lovastatin, combination: cetrimonium + lidocain and estradiol vag.), 87.1% (the greatest number so far!) from the group C and 1.28% from the group D. Surveys of the most prescribed drugs in Zagreb, in Yugoslavia and in the world were also given having proved largely non-rational drug prescribing in this country. Further development of drug formulary concept was discussed, primarily for the drugs paid by the Health Insurance, as well as the unsatisfactory ADR reporting in Yugoslavia. Presented were also the activities of the Committee for Diagnosis, Pharmacotherapy and ADR of the Yugoslav Federal Institute for Health Protection. Publishing of Yugoslav daily defined doses is, according to the authors essential for further systematic monitoring of drug consumption on different levels in this country. It would be impossible to rationalize pharmacotherapy without these data.

Pharmaceutical Preparations↗

[Review of the present status of prevention, prophylaxis and therapy of pertussis and parapertussis].

Whooping cough is endemic throughout the world. It becomes epidemic every 4-5 years (Yugoslavia 3-4 yrs). In Europe its incidence ranges from 0.4 (Hungary) to even 59/100.000 inhabitants (Rumania; Yugoslavia 28), with a general letality of 0.1% (infants: 1%; 75% children who die are younger than one yr). Only 5-10% cases are supposed to be registered. A low socioeconomic status is more and more emphasized as the principal risk factor. Its transmission rate is high (home contacts: 80-100%); infectivity lasts five weeks, disease from the beginning of incubation to the sanation lasts 50-60 days. Female children are more frequently affected. The term "Pertussis syndrome" is more end more used because a similar disease can be caused by various agents (B. pertussis; B. parapertussis: 5%-20%-30% cases; B. bronchiseptica rarely; adenoviruses, RS virus, parainfluenza virus, influenza A and B virus, HSV, CMV, EBV, entero-, adeno-, corona-, rota-viruses; chlamydiae and mycoplasmae). Prior to introducing vaccination, 95% of population have had a typical or atypical form of pertussis. Its differential diagnosis includes pneumonias of various etiology, bronchitis, bronchiolitis during an acute respiratory infection, bronchial asthma, cystic fibrosis, tuberculosis and lymphadenopathy. Morbidity in USA was reduced by vaccination from 157 to 0,5-1,5/100,000 inhabitants; in SR Croatia it was six times reduced in period 1959-1970. According to the official sources 81% of children in Croatia and Yugoslavia get primovaccinated; the 80% level is generally accepted as a rational goal. Immunization schedules differ from country to country. Local and general reactions after combined vaccines are mostly caused by pertussis component.(ABSTRACT TRUNCATED AT 250 WORDS)

Humans↗

[Administration of the "Healthy School" project].

INTRODUCTION: The term of project management is commonly used to describe the work of a team that is handling a special program. In this type of management, a form of leadership which creates environment, enables fast movement of participants through different work phases achieving the common aims, is used [1-4]. The "Healthy School" Project, launched in almost all European countries, has been taking place in Yugoslavia since the end of 1991 [5]. The project developed within the country designed as a health promotion-education intervention study in primary schools. The network of 13 schools on 11 locations representing typical economic, cultural and social environments, was established to cover the country. Although the proposed methodological approach from WHO was followed [6], the specific situation in the country (economic crisis, break down of Yugoslav Federation, the war and international blockade) distated the particular modification. The management of the Healthy School Project in general, and in Yugoslavia particularly, is based upon project management structure (Scheme 1). The objective of this research was to assess the Healthy School project management in Yugoslavia, by measuring causal, intervening and output variables. METHOD: In the process of assessing the management in general, three groups of criteria are commonly used: (a) causal (those that influence the course of developments in the Project), (b) intervening (representing the current condition of the internal state of the Project), and (c) output (that reflect the Project achievements). (a) For the purpose of this study the causal criteria were measured by analyzing the overall management strategy and the level of agreement in objectives of the Project itself, the Project Coordinators and main participants in the Project. (b) The intervening criteria used in this assessment were: the time spent on different project activities, the estimate of the severity of the problems in different aspects of project management, the level of personal influence on different aspects of Project development and overall work motivation and satisfaction of all participants. (c) The outcomes of the given management attempts were analyzed by the following output variables: the number of different types of meetings held, the number of seminars, mass media presentation and articles, the amount of money raised and the number of questionnaires administered. Triangular method was used to gather the data: (1) direct observation, (2) four types of questionnaires and (3) project reports and documentation. Four types of specially designed questionnaires were used to examine four groups of participants (Project Coordinators, School Project Managers, Directors and Project Co-operators). The questionnaires were different in the questions concerning examinees' project tasks and types of external communication, while the questions referring to personal characteristics, general features of the project (goals, common jobs, participation in decision making, motivation and satisfaction) were the same for all groups. RESULTS: The average age of the project participants was 45.50 ranging from 25 to 60 years of age. The oldest group was the group of School Directors, while the youngest were School Co-operators. The project has been run mostly by women, while men were predominantly represented in the group of School Directors. The teaching occupation is presented by 61.8%, the rest being health professionals, mostly of preventive orientation. The analysis and classification of participants goals verify that the personal goals of all participants correspond with the main Project goals. Certain groups have also some additional motives which support their successful and affective movement towards the overall Project goals. The largest problem in all groups appear to be in the field of financing the Project activities (Figure 1). (ABSTRACT TRUNCATED)

Administrative Personnel↗

Practical and legal aspects of forensic autopsy expert team operations.

Finnish forensic experts have investigated remains of the victims of alleged mass violence in the former Yugoslavia in 1996 under the mandate of the United Nations, and in 1998 and 1999 under the mandate of the European Union. The investigative documents later were surrendered to the International Criminal Tribunal for the former Yugoslavia (ICTY). The indictments issued by the ICTY include charges even against the highest authorities of the Federal Republic of Yugoslavia. This study describes the experience gained in organising forensic expert team operations in a foreign state by the Finnish team. The establishment and operation of a forensic expert team in a foreign state involve, among other things, legal issues, often related to differing legal systems. From an independent forensic expert team, great objectivity and self-constraint are expected. Moreover, a clear and sufficiently detailed agreement on the mandate of the team and on the possibility for unhindered and safe access of the experts to the alleged mass graves, as well as the assembling and briefing of the team members and provision of the necessary equipment should be completed before the beginning of the mission. Furthermore, the application of adequate and internationally recognised methods for processing and documenting the examination is essential for team's credibility.

Journal Article↗

Intraspecific diversity within Diaporthe helianthi: evidence from rDNA intergenic spacer (IGS) sequence analysis.

Diaporthe helianthi is the causal agent of sunflower stem canker, a serious pathogen of sunflower in Europe but recorded sporadically in Italy. The genetic diversity of D. helianthi isolates from different geographic origins (Argentina, France, Italy, Yugoslavia, Romania) was investigated using IGS sequences. A 400 bp fragment of the portion of the IGS region flanking the 5' end of the 18S gene was amplified from each isolate. The aligned nucleotide sequences showed intraspecific sequence homology from 99-100% among French/Yugoslavian isolates to 95-100% among Italian isolates. French/Yugoslavian isolates shared 90-92% sequence homology with Italian isolates. The phylogenetic tree obtained from the aligned data revealed three separate groups. Group 1 included all isolates from France and former Yugoslavia and one isolate from Argentina; Group 2 included all Italian isolates and one isolate from Argentina. The most distantly related isolate was that from Romania (Group 3). The average genetic distances among isolates within Group 1 and within Group 2 were 0.22 and 3.29 respectively. The analysis showed that all isolates originating from countries where severe outbreaks of the disease are reported annually (France and former Yugoslavia) form a well defined taxon characterized by relatively low variability. This group is distinct from the group formed by isolates originating from Italy, whose variability is relatively much higher. Results obtained revealed a marked differentiation among pathogen isolates, and members of Group 1 seem not yet to have spread into Italian sunflower-growing areas.

Ascomycota↗

HIV/AIDS in Yugoslavians Infected Abroad.

Retrospective studies have shown that the first HIV positive patient in the Federal Republic (FR) of Yugoslavia (Serbia and Montenegro) was detected among intravenous drug users (IDUs) in 1981. The first two cases of AIDS in Yugoslavia were registered in 19851; one of them was infected in subSaharan Africa. The objective of this paper is to compare the frequency of HIV/AIDS among Yugoslavians infected during their occupational engagement abroad with all other cases of HIV/AIDS in Yugoslavia.

Journal Article↗

Coping strategies in civilians during air attacks.

BACKGROUND: Coping strategies may influence the psychological outcome after a stressful event, both as coping at the time of the event and as strategies of dealing with its consequences after the event. The aim of the study was to investigate coping strategies used by civilians during the air attacks in Yugoslavia in 1999, and their association with the level of exposure, gender and psychological symptoms 1 year later. METHOD: The sample is a non-selective group of 139 medical students from the University of Belgrade, Yugoslavia. Open questions and content analysis were used to assess coping strategies. Symptoms of intrusion and avoidance were assessed, as well as general psychological symptoms. RESULTS: Content analysis of answers to open questions revealed nine categories of coping strategies (sport and walks, leisure activities, talking and gathering, humor, avoidance, philosophical approach, getting information, work, and substance abuse). A cluster analysis identified three groups of students with different styles of coping. Students that used dominantly 'talking and gathering' had the highest, and the ones that mostly used 'leisure activities' the lowest scores on intrusion. There were significant gender differences in how coping strategies were associated with intrusive symptoms. CONCLUSION: The type of coping strategies used during the air attacks may contribute to the level of intrusive symptoms 1 year after the event. Different coping strategies might be effective in men and women to reduce intrusive symptoms. Longitudinal and prospective studies are needed to draw definite conclusions on causal relationships between coping strategies and levels of posttraumatic stress.

Adaptation, Psychological↗

Analysis of recombinant Plum pox virus (PPV) isolates from Serbia confirms genetic homogeneity and supports a regional origin for the PPV-Rec subgroup.

The recent observation of the frequent occurrence of natural recombinant Plum pox virus (PPV) isolates has led to the identification of a distinct PPV subgroup, named PPV-Rec. The diversity, origin and geographical spread of the recombinant PPV isolates belonging to this subgroup remain, however, relatively poorly known. In an effort to further our understanding of these isolates, eight PPV isolates from Serbia, the country from which the first such recombinant (PPV-o6) originated, were characterized. Depending on the genomic region targeted by different typing assays, seven of the eight isolates tested presented discrepancies in their typing behavior. Sequence analysis of the (Cter)NIb-(Nter)CP region confirmed the recombinant nature of these seven isolates which all presented an identical recombination breakpoint identical to previously characterized PPV-Rec isolates. Biological indexing and immunoblot analysis provided indications that asymptomatic infection of the GF305 peach indicator and migration of the coat protein as a double-band in immunoblots may represent conserved and discriminating properties of PPV-Rec isolates. The genetic diversity of PPV-Rec isolates from former Yugoslavia (Serbia, Bosnia and Herzegovina) was estimated to be twice as large as that of the PPV-Rec isolates obtained from all other countries to date (Albania, Bulgaria, Czech republic, Germany, Hungary and Slovakia). These last results are consistent with the hypothesis that former Yugoslavia is the center of dispersion of PPV-Rec. Taken together, the results presented here provide further evidence for the wide distribution and temporal genetic stability of these natural PPV recombinant isolates and provide for the first time a possible scenario for their dispersion throughout central and eastern Europe.

Base Sequence↗