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At least 1,171 records · Page 65Linked to original sources
PubMed1983

Skin variations in blacks.

There are several skin variations normally found in blacks. These variations include Voigt's or Futcher's lines, midline hypopigmentation, pigmentation of the nails, oral pigmentation, plantar hyperpigmented macules, leukoedema of the oral mucosa, pearly penile papules, punctate pits and keratoses of the palms. It is important for health care providers in general and dermatologists in particular to recognize these variations in black skin. In the past, these skin variations have been viewed by physicians and sometimes patients as being abnormal and/or pathologic. Recognition of these benign variations in black skin will aid in correct identification and avoidance of sometimes unnecessary treatment.

Black People↗
PubMedDate not supplied

[Note on the mixed nature, hematic and melanic, of pigmentations in phlebology].

Venous pigmentations are not only tissue deposits of extravasated haemosiderin. Histology reveals that these deposits are often accompanied by excessive melanocyte activity. This combination of various sorts of pigmentation, haematic and melanic, is also found in other non-phlebological ferric hyperchromias. The excess of iron appears to be responsible for the hypermelanosis, but the mechanism is not understood.

Biopsy↗
PubMedDate not supplied

[Apropos of the Mali syndrome].

The authors report two original cases of profuse pigmentation associated with proliferative lesions of the lower limbs, in patients with venous incompetence, suggestive if the syndrome described by Mali and al. in 1963. One case was in fact of Kaposi's disease associated with severe thrombocytopenia which was the cause of death, despite the use of Chloraminophene-Cortancyl. The other case was a woman with profuse pigmentation of the lower limbs associated with multiple disseminated lesions of allergic vasculitis, probably of drug origin. Suppression of the drug and rest led to a marked improvement in the lesions. Although very different from each other, both of these cases are suggestive of Mali's syndrome, but their treatment was totally opposite. The first case, a real vascular neoplasia, required the combination of antimitotic-steroid ; the second case, on the contrary, resolved with rest and a simple elastic bandage, like allcutaneous venous lesions, in particular Mali's syndrome.

Aged↗
PubMed1982

[Incontinentia pigmenti achromians (systematized depigmented nevus)].

Two girls of 1 1/2 und 4 years age and described with linear, arch-like depigementations which appeared in early childhood. In both children no additional abnormalities could be found. The problem of terminology is briefly discussed, and it is proposed to interpret this syndrome as a variant of a systematized naevus depigmentosus. There seems to be no justification for turning this clinical entity into a new syndrome, when the only clinical signs are the characteristic depigmentations without any additional abnormalities.

Child, Preschool↗
PubMed1977

Hypomelanotic canopy of sarcoidosis.

A case of cutaneous hypopigmented macules localized above deep dermal and subcutaneous sarcoid granulomas in a patient with systemic sarcoidosis is presented. Melanin was only sparsely distributed in the upper stratum malpighii. Hypopigmentation is an unusual manifestation of sarcoidosis. With an armamentarium of clinical observation, dermatologists may suspect a hypomelanotic cutaneous diadem overlying a palpable dermal mass to be a visual vignette of a sarcoidal montage requiring diagnostic biopsy.

Adult↗
PubMed1997

[A case of vitamin B12 deficiency with broad neurologic disorders and canities].

The patient was a 48-year-old woman with gait disturbance as her initial symptom. Two years after the onset of the gait disturbance, she developed motor weakness and a sensory disturbance in her limbs, and dementia. On admission to our hospital, the patient's serum vitamin B12 and folic acid levels were low, and she was found to have normochromic anemia. She also had widespread coarse hair and canities was diagnosed. The patient's paresthesia resolved in response to injection of 500 micrograms mecobalamin every other day, and the Hasegawa dementia scale score and the patient's hand grip strength improved. Her gait also improved, and she became able to walk on tiptoe. Her hair returned to normal. Supplementation with high-dose methyl B12 appeared to be effective to some extent in treating a broad range of neurologic disorders besides subacute combined degeneration of the spinal cord. In addition, the hair abnormality may be a marker of vitamin B12 deficiency.

Dementia↗
PubMed1997

Albinism: an update.

Albinism connotes a large group of genetic disorders that are characterized by diminished ocular and oftentimes cutaneous pigmentation. These disorders are generally subclassified as oculocutaneous albinism (OCA) or ocular albinism (OA) based on the extent of their effects on the pigmentation of the skin and hair. Sometimes, different mutations in the same gene can cause OCA or OA.

Albinism↗