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[Airbone contact dermatitis caused by latex exposure: a clinical case].

We describe the case of a nurse who showed eczematous lesions wide-spread over the neck and face. She worked as a attendant to a surgical chamber and wore vinyl gloves because of previous episodes of contact dermatitis caused by rubber gloves. The allergologic examination demonstrated that total IgE was 69.8 kU/1, both the Skin prick tests and the patch test for latex were positive. Persisting her dermatological symptomatology, in the suspicion of a airborne contact dermatitis, the nurse was removed and addressed to administrative functions for detecting the clinical follow-up. Fortunately, the eczematous manifestations spontaneously disappeared immediately after her transfer. In this case the presence of eczema mainly on air-exposed areas was interpreted as a sign of airborne contact dermatitis to latex. The case is reported in that the clinical picture is not very common.

Adult↗
PubMed1975

Allergic contact dermatitis caused by haloprogin.

Haloprogin therapy has been used for years, but no cases of allergic contact dermatitis have been observed. On the basis of the results from several series of patch tests and biopsy findings, the first documented case, to my knowledge, of allergic contact dermatitis caused by haloprogin is reported.

Adult↗
PubMed1997

Acute irritant contact dermatitis: recovery time in man.

Our understanding of the details of the recovery time of acute irritant contact dermatitis (ICD) is limited. We examined skin reactivity to a model surfactant, sodium lauryl sulfate (SLS), on previous acute ICD and normal sites over time with visual grading and noninvasive instruments. Acute ICD was induced on the upper arms of 18 volunteers (aged 30 to 51 years) by occluded application of 1% SLS for 24 h. Previous ICD and normal sites were provoked by occluded application of 2% or 7.5% SLS 30 min daily 4 consecutive days. Skin reactivity was assessed daily by visual erythema scoring (VES), transepidermal water loss (TEWL), skin color reflectance (SCR) and electrical capacitance (EC). Skin function of previous ICD sites assessed by VES, TEWL, SCR, and EC did not normalize until 2 weeks later; all parameters of previous ICD returned to normal after 3 weeks. While skin reactivity to 2% and 7.5% SLS showed no differences between previous ICD and normal sites at 4 weeks, differences of irritant reactivity especially 7.5% SLS between previous ICD and normal sites were significant at 3 weeks post-provocation. Our results demonstrate that irritation evaluated with irritant provocation was long-lasting, even though skin functional parameters assessed by various bioengineering instruments returned to normal. Complete recovery of skin function including irritability after acute ICD induced by 1% SLS was achieved approximately 4 weeks later. The date were generated with a model surfactant; it remains to be determined whether similar responses will be noted with chemicals of different physiochemical properties.

Acute Disease↗
PubMed1985

[Allergic contact dermatitis due to Asteraceae (Compositae). Cross reaction with Liatris spicata].

Case reports of 2 florists suffering from contact dermatitis to Asteraceae, especially to Chrysanthema are described. In addition, in both patients allergic patch-test reactions to another Asteraceae species (Liatris spicata) could be demonstrated. This Asteraceae species is a native flower (Blazing Star) in the USA, but in Germany we find the flower in shops, and sometimes in parks and gardens. Genus Liatris contains about 30 species. Numerous sesquiterpene lactons are isolated from Liatris species which are probably cross reactive with sesquiterpene lactons from Asteraceae native to Europe.

Agriculture↗
PubMed1990

Variability in transepidermal water loss of the skin: evaluation of a method to assess susceptibility to contact dermatitis in epidemiological studies.

Transepidermal water loss (TEWL) has been suggested to be a measure which can be used to identify subjects at risk for the development of contact dermatitis. Transepidermal water loss is high when the barrier function of the skin is impaired. It is assumed that subjects with a high TEWL have skin which is more permeable to substances causing contact dermatitis. The inter-individual and intra-individual variability of simultaneous TEWL measurements and TEWL measurements over a period of three weeks were estimated in healthy individuals. The intra-individual coefficient of variation (CV) of simultaneous measurements was 13.5%. The intra-individual coefficient of variation of the measurements on consecutive days was somewhat higher (15.1%). The intra-individual coefficients of variation were low compared to the inter-individual coefficients of variation. The results indicate that transepidermal water loss is a stable personal characteristic, which can be studied as a risk factor in epidemiologic studies on contact dermatitis.

Adult↗