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How should resources be reallocated between physicians and nurses in Africa and Latin America?

This paper examines ways in which health resources could be reallocated between physicians, nurses and other medical inputs in Africa and Latin America, according to their cost-effectiveness. An underlying question concerns whether countries in Africa and Latin America with decreasing health budgets in the 1980s should reduce the number of highly trained and more expensive workers, i.e. physicians, and redirect resources to less trained and less expensive workers, i.e. nurses. This paper designs a methodology for quantifying the cost-effectiveness of physicians, nurses and government health expenditure in relation to improvements in the population's health status. Direct estimation of the professionals' effectiveness is unsuitable in this 45-country study. Instead, for measuring the unobserved effectiveness of health providers and health expenditures, infant mortality rate has been chosen as the indicator. Infant mortality is an accepted indicator of the health status in a given population. From another viewpoint, neonatal health is dependent on contact with health care services; this means that inappropriate care may increase the likelihood of infant mortality. Therefore, at the same time infant mortality is an indicator of the effectiveness of services. We used a general linear model as a way of estimating the relationship between infant mortality, health manpower and health expenditures. Forty-five countries were examined over three years and 135 observations were included in the final sample. Three scenarios were estimated: (1) African and Latin American countries, or low and middle-income countries, (2) only middle-income and (3) only low-income countries.(ABSTRACT TRUNCATED AT 250 WORDS)

Africa↗

Supply and use of essential drugs in sub-Saharan Africa: some issues and possible solutions.

The paper describes drug supply systems in Africa, both public and private, and concludes that the 'private sector' may have serious drawbacks. Many opportunities exist for improving efficiency and reducing waste; the paper gives evidence for the savings to be made. Finally, there are several issues of specific importance to Africa, namely, geographic and spatial constraints to improving logistics, which are much more severe than elsewhere in the world; the problem of counterfeit drugs; financing of drug supplies and cost recovery; and the impact of the HIV/AIDS epidemic on supply and use of essential drugs.

Acquired Immunodeficiency Syndrome↗

Pioneer medical missions in colonial Africa.

Protestant and Roman Catholic missions pioneered Western medicine and public health in much of Africa decades in advance of health services provided by colonial governments. A century later church-based hospitals and health care programs continue to account for 25% to 50% of available services in most African countries. In view of the important historical and continuing role of medical missions it is remarkable that there have been no systematic scholarly studies of the impacts of these pioneer institutions on the geography of health and social change in colonial Africa. How, for example, was the health of African populations and the areas they inhabited changed by the activities of medical missions? And how did Africans respond to Western medicine and its alien institutional social and technological structures and relations? This paper develops the historical context and conceptual framework for investigating such topics. It presents a detailed research agenda organized around nine themes, each of which suggests a series of interrelated questions. The methodology employs the techniques of medical and historical geography, and is based on comparative, longitudinal case-studies of medical missions at the local level coupled with archival study.

Africa↗

Is paying for health care culturally acceptable in Sub-Sahara Africa? Money and tradition.

In 1987 UNICEF launched the so-called Bamako Initiative, which has as its main objective to improve the sustainability of primary health care in Africa by making people pay for it. The question is raised whether paying for health care is culturally acceptable in African communities. The author argues that 'money' is not a new phenomenon in Africa and that paying for goods and services does not need to conflict with existing traditions of reciprocity in the field of health care. Money is an artifact which is culturally incorporated in a creative manner to satisfy specific needs. Cultural objections to paying for health care, therefore, are unlikely to exist, but how payment should be realised in an effective and just way is another question.

Africa↗

AIDS: conceptual and methodological issues in researching sexual behaviour in sub-Saharan Africa.

This paper describes some of the conceptual and methodological issues encountered in the course of a study of mainly anthropological secondary source materials on sexual behaviour in sub-Saharan Africa. Its aim was to survey and review existing literature and other secondary sources available both outside and within Anglophone sub-Saharan Africa and to evaluate their usefulness to AIDS research and prevention. The review cautioned against the uncritical use of anthropological sources without due regard for their conceptual and methodological status. At the same time it demonstrated important ways in which anthropological insights can inform AIDS research.

Acquired Immunodeficiency Syndrome↗

Underreaction to AIDS in Sub-Saharan Africa.

In those parts of Sub-Saharan Africa most affected by the HIV/AIDS epidemic both public and private reaction to the seriousness of the epidemic have been less than might have been anticipated. This limited reaction weakens national, community and family responses to the epidemic and also reduces the pressure on international donors to provide adequate support. The paper first examines the reasons for underreaction by governments. These reasons include an assessment that successes will not be easily achieved, a reluctance to give leadership in areas of private sensitivity, an awareness of the fragility of the data base, a persistent feeling that it is a disease of foreign origin with a foreign overreaction to the situation in Africa, and the nature of the disease itself with a long latency period, obscure symptoms and an urban bias. Nevertheless, the paper argues that the more fundamental underreaction, shaping the reactions of governments, is that from the community itself. This arises partly from the demonstration that it is a sexually transmitted disease in societies where the discussion of sexual relations between the generations and the sexes has always been difficult and where new religions have in some societies reinforced older attitudes towards the shame of being discovered to have had illicit relationships. However, the main reasons lie in continuing aspects of the cultures which emphasize the multiple antecedents of misfortune and plural explanations of death, an element of predestination in when death takes place, a concept of good fortune--sometimes arising from or demonstrated by sexual activity--which renders misadventure unlikely, and a courage when facing death which is partly attributable to belief about survival beyond this event.

Acquired Immunodeficiency Syndrome↗

Planning health care in South Africa--is there a role for traditional healers?

Developing health policies for the 'post-apartheid' era has become an urgent task of the early 1990s in South Africa. A neglected policy issue thus far has been the question of whether traditional healers have a role to play in future health care, and if so what this should be. Rather than developing positions on these questions, this paper sets out the main debates which need the consideration of health care planners. Arguments for and against traditional healers in health care are presented, and alternatives which could be chosen are outlined. Options adopted by countries on South Africa's borders, Zimbabwe, Mozambique and Swaziland are briefly considered.

Health Planning↗

Professional constructions of a 'lay' illness: 'nerves' in a rural 'coloured' community in South Africa.

As part of a larger study, medical practitioners working in Mamre, a 'coloured' village close to Cape Town, South Africa, were interviewed concerning their use of the term 'nerves' in interaction with their patients. Contrary to the initial perception of researchers and some clinicians, the term is not simply a folk category. It does, however, represent a medium through which psychosocial issues are discussed in the clinical encounter. Differences in the usage of the term by different practitioners seemed to indicate different attitudes towards patient care. The data are presented and discussed in the context of debates concerning the development of more accessible and responsive health services in a future South Africa, and the information gleaned has implications for future training of clinicians.

Black or African American↗

Serological relationships and epitope profiles of isolates of okra leaf curl geminivirus from Africa and the Middle East.

A panel of seven murine monoclonal antibodies (mAbs) was raised against particles of okra leaf curl virus (OLCV), a whitefly-transmitted geminivirus which is prevalent in West Africa. The mAbs detected at least six distinguishable epitopes, two continuous and four discontinuous. In tests with these mAbs, relatively little antigenic variation was found among 24 OLCV isolates from Burkina Faso, Chad, Ghana, Ivory Coast, Nigeria, Oman and Saudi Arabia, each virus isolate reacting with at least five of them. However, on the basis of their reactions with 17 mAbs raised against particles of a group A isolate of African cassava mosaic virus (ACMV), the OLCV isolates could be assigned to two groups, which have geographical distributions that overlap in West Africa. A network of antigenic relationships was revealed by reactions between the OLCV mAbs and other whitefly-transmitted geminiviruses from six plant species in 12 countries. OLCV shared the most epitopes with tobacco leaf curl (African isolates) virus, ACMV, Indian cassava mosaic virus and bean golden mosaic virus. Selected OLCV mAbs are suitable for routine detection of OLCV, and a panel of three mAbs can be used to identify it.

Africa, Western↗

The possible role of tropical medicinal preparations in human carcinoma in Africa.

It is suggested that apart from aflatoxins, plant medicinal preparations containing active compounds imperatorin, dictamine, marmesin and heraclenin may be responsible for some human cancers in Nigeria and perhaps other parts of Africa. Therefore, in this paper, a hypothesis is put forward that these compounds or their reactive (metabolized) types may form epoxides from the 2,3-furan double bonds which may bind tissue macromolecules, DNA, RNA and protein leading to one of the vital steps of environmental carcinogenesis in mammals. This hypothesis has far reaching implications for, besides the examples given, unanalysed plant preparations are widely used in various parts of Africa within traditional methods of healing. Our observation is based on information we now have about AFB1 and is not intended to confirm the roles of double bonds in a vinyl ether system of the active compounds.

Adolescent↗

An overview of cancer management by radiotherapy in Anglophone West Africa.

The problems associated with cancer management particularly by radiotherapy in the developing countries are well known. This paper attempts to present the case as it is in Anglophone West Africa, and to quantify the severity of the problem through a critical analysis of available data based on the experience at the oldest radiotherapy center in West Africa between January 1981 and December 1988. In the whole of the Anglophone West African states with a population estimated at 140 million people, there was only one functional radiotherapy center until 1986 when another unit was commissioned. The paper analyzes the types of tumors managed, radiotherapy facilities available, staffing, and the other operational problems encountered by the Radiotherapy Department of the Lagos University Teaching Hospital in Nigeria. Suggestions are made for the overall improvement of radiotherapy services in the region.

Africa, Western↗

Perspectives in the treatment of mental disorders in developing countries: Africa.

1. Although many parts of Africa are "catching up" with the technological advances of the developed world in many spheres, including medical practice, traditional forms of treatment conspicuously exist side by side with orthodox treatment. 2. None of the few reports of clinical trials from different parts of Africa have taken into account the variations in the clinical presentation of mental disorders, the nutritional status and general physical health of African patient populations in their discussions of the effectiveness of psychotropic agents. 3. Research into traditional forms of treatment and the effectiveness of psychotropic agents in populations in different states of general health and nutrition is seen as a priority.

Adult↗

Peptide mapping of the group-specific antigens from the Australian bluetongue virus (BTV-20) and serotypes from southern Africa and North America.

The Australian bluetongue virus (BTV-20) was compared with six serotypes isolated in southern Africa and North America by peptide mapping of the virus proteins with group antigen properties. The p7 group antigens from each of the seven serotypes analysed did not have identical primary structures and a comparison of shared and unique tryptic peptides has been used as a means of estimating virus relationships. Whereas serological studies have suggested that BTV-20 is closely related to BTV serotypes 4 and 17, comparative peptide mapping of p7 indicates a different set of relationships with viruses from both southern Africa and North America. In contrast with cross-immune precipitation results, peptide mapping of p3 suggest that this protein is not a group specific antigen.

Antigens, Viral↗

The knowledge of medicinal plants in Africa today.

The oral tradition for communication in Africa is stressed as well as the secrecy of the treatments with plants by traditional medicine-men. This makes it difficult to obtain more exact information on all the different aspects of traditional medicine. Nevertheless, some data have been collected in the Francophone countries. In English-speaking Africa efforts to gather information have also been made and a number of valuable reports and books published. A number of books report our present knowledge in the African regions south of the equator, mainly in Zambia.

Africa↗

The inappropriate use of traditional medicines in South Africa.

Traditional medicines are culturally very important to the Zulu population of Southern Africa. The inappropriate use of herbs has however, resulted in numerous fatalities, invariably in children. This paper briefly summarises the belief of the Zulu population in traditional remedies, together with an outline of the problems at present being experienced in South Africa. A further note on the personal impressions and experiences of the authors and description of one such toxic herbal remedy, including use, toxic action and research carried out to date, are also given.

Child↗

Mapping the potential distribution of Phlebotomus martini and P. orientalis (Diptera: Psychodidae), vectors of kala-azar in East Africa by use of geographic information systems.

The distribution of two principal vectors of kala-azar in East Africa, Phlebotomus martini and Phlebotomus orientalis were analysed using geographic information system (GIS) based on (1) earth observing satellite sensor data: Normalized Difference Vegetation Index (NDVI) and midday Land Surface Temperature (LST) derived from advanced very high resolution radiometer (AVHRR) of the global land 1km project of United States Geological Survey (USGS), (2) agroclimatic data from the FAO Crop Production System Zone (CPSZ) of the Intergovernmental Authority on Development (IGAD) sub-region, and (3) the FAO 1998 soils digital map for the IGAD sub-region. The aim was to produce a predictive risk model for the two vectors. Data used for the analysis were based on presence and absence of the two species from previous survey collections in the region (mainly Ethiopia, Kenya and Somalia). Annual, wet season and dry season models were constructed. Although all models resulted in more than 85% positive predictive values for both species, the best fit for the distribution of P. martini was the dry season composite (NDVI 0.07-0.38 and LST 22-33 degrees C) with a predictive value of 93.8%, and the best fit for P. orientalis was the wet season composite (NDVI -0.01 to 0.34 and LST 23-34 degrees C) with a predictive value of 96.3%. The two seasonal composites models derived from satellite data were largely similar with best fit models developed based on the CPSZ climate data: average altitude (12-1900m), average annual mean temperature (15-30 degrees C), annual rainfall (274-1212mm), average annual potential evapotranspiration (1264-1938mm) and readily available soil moisture (62-113mm) for P. martini; and average altitude (200-2200m), annual rainfall (180-1050mm), annual mean temperature (16-36 degrees C) and readily available soil moisture (67-108mm) for P. orientalis. Logistic regression analysis indicated LST dry season composite of the satellite data, average altitude, mean annual temperature and readily available soil moisture of the CPSZ data as the best ecological determinants for P. martini while LST annual composite was the only important ecological determinant for P. orientalis. Spearman's rank correlation revealed several factors to be important determinants for the distribution of the two vectors. None of the soil types analysed appeared to be important determinant for the two species in East Africa, unlike in Sudan where P. orientalis is mainly associated with eutric vertisol (black cotton clay soil).

Africa, Eastern↗

Risk factors for childhood mortality in sub-Saharan Africa. A comparison of data from a Demographic and Health Survey and from a Demographic Surveillance System.

OBJECTS: In a comparative analysis, the effect of risk factors for childhood mortality in Burkina Faso, sub-Saharan Africa, were computed from Demographic and Health Survey (DHS) and Demographic Surveillance System (DSS), two very different sources. While most analyses so far determined levels of risk factors, this analysis focuses on the effects of those risk factors. METHODS: Mortality levels are often calculated by strata of risk factor levels separately for each factor. In this publication, their effect was modelled jointly by survival analysis, using all-cause childhood mortality as outcome variable. All live births in rural Burkina Faso in the period of 1994-1998 recorded by the DHS survey Burkina Faso 1998-1999 (5018 births) and the Demographic Surveillance System based in Nouna, western Burkina Faso (6196 births) were included. RESULTS: A simultaneous estimation of hazard rate ratios by a Cox regression model yielded similar estimates for the DHS and DSS data, in line with previous findings based on the Nouna DSS alone. Although DHS surveys do not include children whose mothers had died, ignoring the strong risk factor "death of the mother" does not strongly affect DHS-based results. CONCLUSIONS: Despite the different nature of survey (DHS) and longitudinal (DSS) data, these findings demonstrate that, despite some limitations, results derived from DHS surveys are broadly comparable to DSS data. Both are valuable tools for assessing the importance of risk factors for childhood mortality in sub-Saharan Africa, and they could be combined for better predictions.

Adolescent↗

Substance use and multiple victimisation among adolescents in South Africa.

The aims of the study were to examine the relationship between multiple victimisation and drug use, and the role of drug use and other intra-personal, peer, parental and environmental factors in predicting multiple victimisation among adolescents in South Africa. A cross-sectional design was employed. The participants comprised 1474 male and female adolescents aged between 12 and 17 years, from Durban and Cape Town. They completed questionnaire measures assessing demographic characteristics; self, peer and parental drug use; self and peer delinquency; parental child-centredness and rules; and community drug availability and exposure to violence on television. A measure of multiple victimisation assessed whether or not the respondents had experienced two or more different types of violence in their lifetime. There was a significant association between frequency of tobacco, alcohol and marijuana use and multiple victimisation. Significant predictors of multiple victimisation in multiple logistic regression analyses were variables within intra-personal, peer, parental and environmental domains. Victimisation prevention programmes in South Africa should be comprehensive and target adolescents' drug use as well as their other psychosocial risk factors.

Adolescent↗