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At least 1,153 records · Page 64Linked to original sources
PubMed1990

New analogues of rosaramicin isolated from a Micromonospora strain. I. Taxonomy, fermentation, isolation and physico-chemical and biological properties.

Antibiotics 6108 A1, B, C and D, a new series of analogues of rosaramicin, were found together with rosaramicin, juvenimicin A4 and M-4365 A1 from the cultured broth of strain BA06108 which was assigned to be a new species of Micromonospora. 6108 A1 and C showed inhibitory activity against Gram-positive and some Gram-negative bacteria as potent as rosaramicin and exhibited low acute toxicity in mice. However, 6108 B showed less potent antimicrobial activity and 6108 D showed higher toxicity than those two antibiotics.

Animals↗
PubMed1992

Dethymicin, a novel immunosuppressant isolated from an Amycolatopsis. Fermentation, isolation, physico-chemical properties and biological activities.

In the course of screening for immunomodulators inhibiting the mixed lymphocyte culture reaction (MLCR), we found a novel immunosuppressant, dethymicin in mycelium of Amycolatopsis mediterranei MI710-51F6. From physico-chemical properties and biological activity it is different from immunosuppressants produced by microorganisms such as cyclosporins, FK506 and rapamycin. It inhibited immune responses in vitro and in vivo, and prolonged skin allograft in rats.

Actinomycetales↗
PubMedDate not supplied

Isolation, purification and characterization of polypeptides of influenza and parainfluenza viruses. Note III. Polypeptides of three influenza virus strains isolated in Romania.

An analysis is presented of the nature, number and relative molecular mass of the polypeptides of three influenza virus strains-A/Romania 1/73 (H3N2), A/Romania 1/75 (H3N2), and B/Romania 34/74-isolated during different epidemic outbreaks. The results obtained indicate some similarities between the protein subunits of the two influenza A virus strains (as concerns virus surface and nucleocapsid components) and point out the particular properties of the influenza B strain.

Orthomyxoviridae↗