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Results for “Thyroid Function Tests”

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At least 1,153 records · Page 64Linked to original sources
PubMed1982

The oral TRH stimulation test. A new diagnostic tool in "non-toxic" multinodular goitre.

We have developed a 28-hour TRH stimulation test based on the FT3I response to repeated oral TRH stimulation. The normal FT3I response in 15 controls was greater than or equal to 40 arb.U. Twenty-five euthyroid patients with multinodular goitre were studied. Fourteen had normal FT3I responses and normal basal levels of serum T4, FT4I, serum T3 and FT3I. Eleven patients had FT3I responses below 20 arb.U. Although the patients' individual basal values of serum T4, FT4I, serum T3 and FT3I were within the normal range, the median values of FT4I, serum T3 and FT3I were significantly elevated compared to the controls, suggesting that these patients were in a "pretoxic" condition. This assumption seems to be supported by the fact that 3 of these patients subsequently became frankly hyperthyroid, whereas all patients with normal FT3I response remained euthyroid. A comparison between the TSH response to i.v. TRH and the FT3I response to oral TRH showed concordance in 21 of the 25 patients studied.

Administration, Oral↗
PubMed1993

[Reversibility of dementia in hypothyroidism].

Thirteen percent of all dementia disorders are potentially reversible. Hypothyroidism is among the most frequent causes of reversible dementias. Although it is generally accepted that dementia symptoms in hypothyroidism can be significantly reduced, many questions about the therapeutic efficacy are unexplained. It has not been systematically investigated which psychopathological symptoms respond well to thyroid hormone substitution, how long the treatment should last and whether duration of symptoms or severity of dementia have an influence on the degree of remission of psychopathological impairment. We investigated these questions in two prospectively studied cases with dementia in hypothyroidism.

Dementia↗