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The practical effect of obesity on the insured life--relative risks associated with obesity and various disease states--"the imparied life".

The 1979 Build and Blood Pressure Study was based on 4,200,000 North American life assurance policies issued after medical examinations between 1950 and 1971 and studied over the period of 1954 to 1972. The experience included 106,000 deaths. The study investigated the mortality experience of overweight lives assured by cause of death. Actual mortality was significantly above that expected for the following causes: diabetes mellitus, cerebrovascular disease, coronary artery disease and hypertensive heart disease. The implications of these observations are discussed.

Actuarial Analysis↗

[Chronotherapy of obesity. II. Variations in eating behavior in the obese after fenfluramine treatment in relation to time of administration].

The administration of Fenfluramine (F.) in a single dose in the morning provokes a different effect on eating behavior (E.B.) in comparison with the administration of the same dose three times/day. It is observed a shorter duration of eating (p less than 001); a decrease of total kcalories ingested during the day, and hunger feeling. These results are reviewed on the basis of present knowledge on drug-kinetic and on previous work in our laboratory which documented higher decrease of body weight and adipose mass when the F. was administered in a single dose in the morning than in the afternoon or three times a day.

Adult↗