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Jaw fractures in Stockholm 1988-90. Changing trends in injury dynamics over a 10 year interval.

This paper presents a review of injury dynamics of jaw fractures sustained by 1374 patients in the county of Stockholm during 1978-1980 = M1 (795 patients) and 1988-1990 = M2 (579 patients). The material comprised 1620 mandibular (M1 = 904, M2 = 716) and 439 maxillary (M1 = 249, M2 = 190) fractures. Forty-three per cent of the mandibular fractures and 40% of the maxillary fractures were single fractures in M1. The corresponding figures for M2 were 35% and 43%. During both periods the anatomical region most frequently fractured was the mandibular condyle (M1 = 35%, M2 = 29%). Violence was the cause in 39% of all fractures and 42% of the mandibular fractures (M2). This compared to M1 confirms other reports of altered trends in jaw fractures related to violence during the 1980's. The proportion of jaw fractures caused by traffic increased slightly between the periods.

Accidental Falls↗

Masticatory muscle function in patients treated for condylar fractures of the mandible.

The activity of the temporal and masseter muscles and of the upper lip was examined by electromyography in five adults and in five children who had sustained uni- and bilateral fractures of the mandibular condyle. Electromyographic recordings were done in the postural position of the mandible, during maximal bite in the intercuspal and retruded mandibular positions, during chewing and swallowing of peanuts and during swallowing of water. In the children, who were examined on three occasions after the trauma, a reduced muscle activity was found shortly after the trauma, but it had normalized at follow-up examination 1 year after the injury. The adults, who were examined 4-6 years after the trauma, had, in general, normal muscle function. In subjects with a unilateral fracture, no difference in muscle activity was found between the two sides. An enlarged distance between the retruded and intercuspal positions of the mandible did not, in these subjects, seem to influence the muscle activity during the functions studied.

Adolescent↗

Growth changes and orthodontic treatment in a patient with condylolysis.

A patient with acquired bilateral degeneration of the mandibular condyles was treated orthodontically. The flattening of condyles and the shortening of the ramus began at adolescence. The facial profile changed to a convex type, with a marked mandibular retrognathia and severe Class II malocclusion. The cause seems to be due to a condylolysis of the mandible.

Child↗

Gas in the temporomandibular joint: computed tomography findings. Report of 3 cases.

In each of 3 patients referred for computed tomographic examinations of the temporomandibular joint, a gas collection was observed in the inferior space of the joint. The gas was observed on the posterosuperior surface of the mandibular condyle in the open mouth position in each patient. Each of 2 patients had saucer-shaped bone resorption of the mandibular condyle adjacent to the gas; 1 patient had no remarkable bone abnormality. A history of temporomandibular joint puncture or facial trauma was denied by all 3 patients.

Adult↗

Arrangement of D-periodic collagen fibrils and association of proteoglycans with fibrils in the synovium of the mouse temporomandibular joint.

The present study was performed to examine changes in the arrangement of D-periodic collagen fibrils in the synovium of the growing temporomandibular joint in mice. At 1 week of age, the mandibular condyle was undeveloped, and only a few collagen fibrils were recognizable in the subintimal layer of the synovium. At 8 weeks, the mandibular condyle was structurally developed with an increase of collagen fibrils in the synovium; a fully mature condyle was observed at 6 months of age. The close association of proteoglycans with collagen fibrils in the synovium of the growing joint was examined by both conventional and energy-filtering transmission electron microscopy of cupromeronic blue-stained specimens. Proteoglycans were associated with D-periodic collagen fibrils in the short filamentous form in random fashion at 1 week of age, but in a regular pattern with D-periodicity at 6 months. These associations in the synovium could be correlated with the mechanical character of the temporomandibular joint.

Age Factors↗

Hodgkin's disease of the jaws. Review of the literature and report of a case.

Hodgkin's disease of the jaws is extremely rare. A review of the literature has revealed only seven previously reported cases, five in the mandible and two in the maxilla. A new case of Hodgkin's disease of the mandible is reported. The patient had features of chronic osteomyelitis of the mandible. After resection, a Hodgkin's type of infiltrate was found in the mandibular condyle. The histologic subtype was lymphocyte-depleted, and the clinical staging was IV-B. The patient died 7 months after the mandibular lesion was discovered. From previous reported cases and this additional case, it appears that the prognosis for patients with Hodgkin's disease of the mandible is very poor.

Adult↗

Shape-coordinate analysis of skeletal changes induced by rapid maxillary expansion and facial mask therapy.

The aim of this study was to evaluate maxillary and mandibular shape/size changes by means of Bookstein's shape-coordinate and tensor analysis in children with Class III malocclusions treated with rapid maxillary expansion and a facial mask in order to define optimum timing of intervention for this type of therapy. The treated group (46 subjects, 26 females and 20 males) was divided into two subgroups according to the stage of dentitional development. The early-treated group consisted of 23 subjects treated in the early mixed dentition (mean age at Time 1, 6 years 9 months +/- 7 months); the late-treated group included 23 subjects treated in the late mixed dentition (mean age at Time 1, 10 years 3 months +/- 1 year). The mean treatment period was about 11 months. The control group (32 subjects with untreated Class III malocclusion, 18 females and 14 males) also was divided into two subgroups (an early control group, 17 subjects in the early mixed dentition, and a late control group, 15 subjects in the late mixed dentition). Maxillary triangles (point T, the most superior point of the anterior wall of sella turcica, point FMN, the fronto-maxillary-nasal suture, and point A) and mandibular triangles (point Condylion, point Gonion, and point Pogonion) were digitized on cephalograms in both groups at Time 1 and Time 2. Combined facial mask and rapid maxillary expansion therapy produced a significant enhancement of the forward growth of the maxilla and significantly more upward and forward direction of growth of the mandibular condyle (leading to smaller increments in mandibular total length, Co-Pg) in the early-treated group when compared with controls and to the late-treated group. Both maxillary size and mandibular size were significantly affected by treatment in the early mixed dentition. The results of this study indicate that orthopedic treatment of Class III malocclusion induces favorable size and shape changes both in the maxilla and mandible, and that this combined treatment approach is more effective in the early mixed dentition than in the late mixed dentition.

Age Factors↗

Tissue-engineered osteochondral constructs in the shape of an articular condyle.

BACKGROUND: An entire articular condyle engineered from stem cells may provide an alternative therapeutic approach to total joint replacement. This study describes our continuing effort to optimize the chondrogenic and osteogenic differentiation from mesenchymal stem cells toward engineering articular condyles in vivo. METHODS: Primary rat bone-marrow mesenchymal stem cells were induced to differentiate into chondrogenic and osteogenic lineages in vitro and were suspended in polyethylene glycol-based hydrogel. The hydrogel cell suspensions, each at a density of 20 x 10(6) cells/mL, were stratified into two separate layers that were molded into the shape and dimensions of an adult human cadaveric mandibular condyle by sequential photopolymerization. The osteochondral constructs fabricated in vitro were implanted in the dorsum of immunodeficient mice for twelve weeks. RESULTS: De novo formation of articular condyles in the shape and dimensions of the adult human mandibular condyle occurred after a twelve-week period of in vivo implantation. Histological evaluation demonstrated two stratified layers of cartilaginous and osseous tissues, and yet there was mutual infiltration of cartilage-like and bone-like tissues into each other's territories. The cartilaginous portion was stained intensively to safranin O and expressed immunolocalized type-II collagen. Chondrocytes adjacent to the tissue-engineered osteochondral junction were enlarged and expressed type-X collagen, typical of hypertrophic chondrocytes. The osseous portion contained bone trabeculae-like structures and expressed immunolocalized type-I collagen, osteopontin, and osteonectin. CONCLUSIONS: A cell encapsulation density of 20 million cells/mL with in vivo incubation for twelve weeks yields further tissue maturation and phenotypic growth of both cartilage-like and bone-like tissues in the tissue-engineered articular condyle.

Animals↗

Dental devices; effective date of requirement for premarket approval; temporomandibular joint prostheses--FDA. Final rule.

The Food and Drug Administration (FDA) is issuing a final rule to require the filing of a premarket approval application (PMA) or a notice of completion of a product development protocol (PDP) for certain devices, namely, the total temporomandibular joint (TMJ) prosthesis, the glenoid fossa prosthesis, the mandibular condyle prosthesis (for permanent reconstruction), and the interarticular disc prosthesis. At a later date, FDA will propose reclassifying from class III into class II the generic type of temporary mandibular condyle prosthesis intended for temporary reconstruction following surgical ablation of malignant and benign tumors. This action establishing the effective date of the premarket approval requirement for certain devices is being taken under the Federal Food, Drug, and Cosmetic Act (the act), as amended by the Medical Device Amendments of 1976 (the 1976 amendments), the Safe Medical Devices Act of 1990 (the SMDA), and the FDA Modernization Act of 1997 (FDAMA).

Device Approval↗

Transoral resection of a condylar osteochondroma: report of case.

A rare case of osteochondroma (osteocartilaginous exostosis) of the mandibular condyle is described; this represents the seventh documented case in the English language literature. Treatment consisted of transoral surgical resection which maintained condylar integrity. No maxillomandibular fixation was placed and the patient's mandibular function was undisturbed. Postoperatively, mandibular deviation was minimal.

Aged↗

[The contribution of standard radiographs in the evaluation of masticatory system dysfunction].

Conventional x-ray films (orthopantomogram, teleradiogram) visualize many signs of dysfunction of the manducatory apparatus (DAM). Progress in our knowledge of the pathophysiology of DAM has brought new light to these radiographic signs. The orthopantomogram allows an assessment of modifications in muscle insertion zones secondary to their dysfunction and, more difficulty, the articular remodeling of the TMJ, mainly of the mandibular condyle and the articular space. The lateral teleradiogram studied by architectural and structural analysis provides information on the biomechanical balance of the cranio-facial structures and, especially, on the position of the mandibular rami. These standard radiograms are indispensable in the differential diagnosis, useful in the etiological diagnosis and are preliminary examinations prior to using other imaging techniques (MRI, CT). Standard films are easily reproducible for post-therapy follow-up.

Biomechanical Phenomena↗

Histological changes in the articular eminence and mandibular fossa during growth of the rhesus monkey (Macaca mulatta).

Unlike the mandibular condyle, the temporal component of the temporomandibular joint (TMJ) has been the object of relatively few investigations concerning its growth and remodeling. This report provides qualitative and quantitative documentation of microanatomical changes in the mandibular fossa and articular eminence during growth of the rhesus monkey (Macaca mulatta). The thickness of the fibrous articular tissue and the presence of cartilage cells in its deeper layers were examined histologically in 43 rhesus monkeys at five maturational levels (neonate, infant, juvenile, adolescent, and young adult). Absolute thickness of the articular tissue increased with maturational level in all areas studied, with the increase somewhat more pronounced on the posterior slope and crest of the articular eminence than in the roof of the mandibular fossa. Relative to condylar size, an increase in articular-layer thickness characterized the first three maturational levels, and was followed by a decrease during adolescent and young-adult stages. Articular tissue in the fossa roof constituted a steadily decreasing fraction of the total articular-tissue thickness with age, while relative thickness of the tissue on the posterior slope and crest of the eminence increased with age. These results parallel those obtained for the mandibular condyle, and they are best interpreted to indicate that forces delivered to the joint become directed more anteriorly with age. The overall pattern of topographical variation in articular-tissue thickness and cartilage-cell distribution suggests that greater loading of the lateral aspect of the TMJ, postulated in the human TMJ by various workers, may not be as pronounced in the monkey.

Animals↗

Long-standing bilateral dislocation of the mandible in the elderly.

The aetiology of long-term bilateral dislocation of the mandibular condyle in the elderly patient is discussed. Two of the author's cases are used to illustrate the different ways in which the above condition may arise. The treatment of the above cases is discussed, one form of treatment being a modification by the author of a technique described by Archer & Gould, in which Gunning's splints fitted with a fulcrum were wired into the edentulous jaws. The dislocated mandible was then subjected to elastic traction. A second case of 5 year's duration had bilateral condylectomies performed, using a different surgical approach on each side in order to try and find a technique which would afford better access to the condyle when it is in the temporal fossa than the more usual pre-auricular approach.

Aged↗

[The morphogenesis of the temporomandibular joint considered in its phylogenic aspects in vestibular orientation].

Comparative phylogenic movements of skull points can be obtained using vestibular orientation and skulls from various mammals after reducing the bimediocondyle distance to approximately 100 mm (as in man). With this method, the condyle is seen to move backwardly and rise in a very thin bony area which will be covered by the increasing volume of the encephalus. A "mandibulocerebral" index of less than 100 is a criteria of humanoid species. A part posterior to the fixed zone in primate which will become the temporal condyl in man is eroded by the mandibular condyle. The tympanum migrates upwardly and posteriorly in primates and turns forwardly in man, contributing to limit the glenoid cavity posteriorly. The anterior limit to mandibular propulsion in primates is the intercanine bite; this disappears in man as does the post-glenoid apophysis which is reduced to a tubercle with no limiting effect. In man, function of the temporomandibular joint depends on its more delicate construction than in primates. The major humanoidizing processes alone, i.e. posterior movement of the jaws and their reduced volume, bipedism, and amplification of the cerebral volume, are sufficient to explain this situation which results from the effect of phylogenic evolution.

Animals↗

Uncommon manifestations of histiocytosis X.

Histiocytosis X is a group of disorders of uncertain etiology with a variety of manifestations that are usually related to the age of the patient. Treatment consists of local curettage, irradiation and chemotherapy. The prognosis depends on the systems involved. The oral and perioral tissues are occasionally involved and often lead to the diagnosis. We report a case with spinal cord involvement and a case of facial nerve paralysis secondary to involvement of the petrosal bone. Also included is a case of involvement of the mandibular condyle.

Bone Diseases↗

Intensive treatment of severe Class II malocclusions with a headgear-Herbst appliance in the early mixed dentition.

In the correction of large sagittal discrepancies in the relationship between the maxilla and the mandible, the orthopedic effect of treatment is often of small magnitude when compared with the dentoalveolar changes. A group of patients with severe Class II malocclusions were treated to assess the effects of a therapeutic approach which specifically took into consideration important factors such as type of anchorage, amount of force, age at start of treatment, and intensity of treatment to obtain the maximal orthopedic improvement. A special headgear-Herbst appliance was designed and short intensive treatment, lasting 5 months, was performed in the very early mixed dentition. Comparison with an untreated control group revealed the dramatic effects of treatment. The overall average change in the sagittal relationship between the maxillary and mandibular teeth was 7.5 mm after active treatment. The posteriorly directed effect on the maxilla of 3.1 mm was due to a combination of distal movement of the dentoalveolar arch and of posterior translation of the basal portion of the maxilla. The anteriorly directed effect upon the mandible of 4.4 mm was due mostly to anterior movement of the basal part of that bone, with a small part resulting from labial movement of the lower incisors. This appeared to be the result of a stimulation of growth of the mandibular condyles, a change in mandibular morphology, and an anteroinferior change in position of the condyles with a possible anterior translation of the glenoid fossa. After a 10-month posttreatment period during which an activator was used during the initial 6 months, a new comparison between the treated group and the control group was made. Growth continued to the same extent in the treated group as in the control group. However, a tendency toward relapse in overjet of 2.3 mm was observed, leading to some modifications in the treatment approach in recently started cases. A short period of interceptive orthopedic treatment in the very early mixed dentition may be indicated to correct skeletal deviations and establish a normal relationship between the maxilla and the mandible. Treatment could then be followed by a period without appliance wear until final dentoalveolar adjustments, if necessary, are made in the permanent dentition.

Activator Appliances↗

Computerized tomographic findings in the temporomandibular joint in patients with psoriatic arthritis.

Three male patients with psoriatic arthritis of the temporomandibular joint (TMJ) were evaluated by computerized tomography (CT). Only one patient showed changes of the mandibular condyle on the panoramic view, which failed to show the condition in the other 2 patients. All 3 had normal conventional radiographs of the affected TMJ. In all 3 cases the high resolution CT scan demonstrated significant changes of the mandibular condyle and glenoid fossa, which were consistent with the clinical diagnosis of psoriatic arthritis of the TMJ.

Adult↗