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At least 1,153 records · Page 64Linked to original sources

[Severe cytomegalic inclusions disease in the fetus of a woman immunized before pregnancy].

After detection of a fetal microcephaly at 24 weeks gestation, we performed an amniocentesis at 29 weeks with chromosomal and polymerase chain reaction (PCR) search for viral contamination. Cytomegalovirus (CMV) infection was confirmed by PCR although the mother had previously been tested as immunized for CMV prior to conception. Abortion was induced; the fetus presented clinical CMV injuries confirmed by positive tissue culture (liver, brain and lungs). Recent publications have reported similar observations with variable viral strains. These findings point out the importance attentive search for ultrasonographic signs suggestive of fetal CMV infection.

Abortion, Induced↗

Exposure of sero-positive gilts to swine influenza virus may cause a few stillbirths per litter.

Six pregnant gilts were purchased from a high health herd and were found to be serologically positive for swine influenza virus (SIV) subtype H3N2. Three of the gilts, at 80 to 82 days of gestation, were experimentally exposed a second time to the same SIV subtype--H3N2. No clinical signs resulted from the second exposure to SIV and hemagglutination-inhibition (HI) titers for SIV at 4 weeks postexposure were unchanged suggesting that the gilts had not been reinfected. However, the second exposure to SIV affected the number of pigs born alive. Each of the 3 litters from the twice exposed gilts suffered 2 or 3 stillborn piglets per litter. In contrast the 3 matched, sero-positive gilts that were not exposed to SIV (controls) had no stillborn piglets. These differences were statistically significant using a t-test for unequal variances (P = 0.0086). Sera from 2 of the stillborn piglets were negative for HI antibodies and there was no indication from the pigs born alive that the H3N2 virus had crossed the placenta.

Abortion, Veterinary↗

[HIV-infected women's decision to continue or terminate pregnancy].

Our purpose was to determine how women's knowledge of HIV seropositivity influenced their decision on whether to continue pregnancy. The study included 2,023 pregnant women from 220 maternities through France, 595 in 1987, 691 in 1988 and 737 in 1989. Approximately one half decided to continue pregnancy. This proportion was higher in the Paris region (58.9 percent) than in the other regions of France (38.2 percent). Motivations for continuing pregnancy included a visceral desire to have a child, a means of transcending one's mortality, a gift to the partner, a means of rehabilitation, a denial of the pathologic state or the conviction that the infant will be unaffected. Motivations for terminating pregnancy included fear of contaminating the infant, fear that pregnancy could accelerate their own disease progression and fear that the infant will become orphaned. The attitude of physicians towards pregnancy in HIV infected women is discussed. The discovery of an effective treatment decreasing materno-fetal transmission and/or an approach to prenatal diagnosis could offer solutions to this difficult dilemma.

Abortion, Induced↗

Fifth disease: role for nurses in pediatric practice.

Parvovirus B19 infection is a common childhood disease. Infection is usually mild but may have serious consequences in pregnant women. Nurses in pediatric practice may be the only health professionals in a position to recognize and intervene in this potentially serious condition in certain high risk individuals.

Abortion, Spontaneous↗

Beware sheep!

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Abortion, Spontaneous↗

[Toxoplasmosis and abortion in patients at the O'Horan Hospital of Merida, Yucatan].

The relationship between abortion and infection by Toxoplasma gondii was analyzed in 100 cases of spontaneous abortions, 51 of which corresponded to single abortions and 49 to cases with a history of repeated abortions. The Sabin-Feldman test was used for the detection of specific antibodies. Parasites were identified and isolated in the aborted material; sections were stained by Hematoxilin-Eosin, processed for indirect immunofluorescence and inoculated into mice. Antibodies to Toxoplasma were detected in 47 percent of the total study population. Positive identification of parasites in the decidua and corionic villae was established in 2 percent of the patients studied. Parasites could only be isolated in one of these patients. Both cases belonged to the group with positive serology and antibody titers of 1:64 and 1:128, and having experienced a single abortion. There was no significant statistical difference with regard to antibody titers between the single abortion and repeated abortion groups. Our results indicate an important causative relationship between toxoplasmosis and abortions in Mérida, Yucatán, México.

Abortion, Habitual↗

[Complex treatment of toxoplasmosis in women with a history of severe obstetric problems].

A total of 43 females with chronic required toxoplasmosis and habitual abortion were exposed to comprehensive investigation and etiological treatment with regard to toxoplasmosis. In the majority of cases combined involvement of various organs and systems was revealed. Treatment of 14 pregnant women in presence of threatened abortion positively affected not only the course and outcomes of advancing pregnancies but the development of future pregnancies as well.

Abortion, Habitual↗

Ovine enzootic abortion: experimental studies of immune responses.

Eight pregnant and four non-pregnant ewes were exposed to experimental oral infection with the chlamydial agent of ovine enzootic abortion. Four non-pregnant ewes received a sham inoculum. Immune responses were investigated using a complement fixation test (CFT), a delayed-type hypersensitivity (DTH) skin test and a lymphocyte transformation assay (LTA). When these responses were correlated with clinical observations it was concluded that fetopathy occurred in those ewes which failed to mount or mounted only weak DTH responses. High antibody titres were not an indication of protective immunity; in pregnant animals there was evidence of an inverse correlation between DTH and humoral responses as detected by the CFT. In the LTAs, chlamydia specific blastogenesis was recorded in all infected sheep but there was little correlation with clinical findings.

Abortion, Veterinary↗

Deaths due to sexually transmitted diseases. The forgotten component of reproductive mortality.

Reproductive mortality has three principal components: deaths related to pregnancy, contraception, and sexually transmitted diseases (STDs). The last component is usually overlooked. In 1955, deaths due to STDs constituted a minimum of 32% of all reproductive mortality in the United States; in 1965 and 1975, the percentages were 32% and 20%, respectively. Pelvic inflammatory disease and syphilis account for most deaths due to STDs. In 1979, the mortality rate due to pelvic inflammatory disease was 0.29 deaths per 100,000 women aged 15 to 44 years; the corresponding figure for syphilis was 0.17. If cervical cancer is viewed as an STD, then deaths due to this cause alone (approximately 6,800 per year) would far outnumber deaths due to all other reproductive causes combined. Surveillance of reproductive mortality in the United States should be expanded to encompass deaths due to STDs.

Abortion, Legal↗